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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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National NeuroAIDS Tissue Consortium Resource Report Resource Website 10+ mentions |
National NeuroAIDS Tissue Consortium (RRID:SCR_007323) | NNTC | biomaterial supply resource, brain bank, material resource, tissue bank | Collects, stores, and distributes samples of nervous tissue, cerebrospinal fluid, blood, and other tissue from HIV-infected individuals. The NNTC mission is to bolster research on the effects of HIV infection on human brain by providing high-quality, well-characterized tissue samples from patients who died with HIV, and for whom comprehensive neuromedical and neuropsychiatric data were gathered antemortem. Researchers can request tissues from patients who have been characterized by: * degree of neurobehavioral impairment * neurological and other clinical diagnoses * history of drug use * antiretroviral treatments * blood and CSF viral load * neuropathological diagnosis The NNTC encourages external researchers to submit tissue requests for ancillary studies. The Specimen Query Tool is a web-based utility that allows researchers to quickly sort and identify appropriate NNTC specimens to support their research projects. The results generated by the tool reflect the inventory at a previous time. Actual availability at the local repositories may vary as specimens are added or distributed to other investigators. | human immunodeficiency virus, nervous tissue, cerebral spinal fluid, blood, tissue, brain, neuromedical data, neuropsychiatric data, tissue, plasma, peripheral blood mononuclear cell, serum, urine, spinal cord, nervous tissue, pituitary gland, trigeminal ganglia, dorsal root ganglion, peripheral nerve, lymph node, liver, spleen, adipose tissue, bone marrow, muscle, hair, heart, thymus, kidney, lung, eye, brain, ante-mortem, post-mortem, normal, subsyndromic, minor cognitive motor disorder, hiv - associated dementia, cytomegalovirus encephalitis, neurological impairment, traumatic brain injury, neurocognitive disease, frozen, fixed, aids, one mind tbi, asymptomatic neurocognitive impairment, minor cognitive disorder, gene array, snp |
is listed by: One Mind Biospecimen Bank Listing is related to: Manhattan HIV Brain Bank is related to: CHARTER - CNS HIV Antiretroviral Therapy Effects Research |
Human immunodeficiency virus, Neurocognitive disease, Normal, Subsyndromic, Minor Cognitive Motor Disorder, HIV - Associated Dementia, Cytomegalovirus Encephalitis, Neurological impairment, Infectious disease | NIMH ; NINDS ; NIH Blueprint for Neuroscience Research |
Public: The NNTC encourages external researchers to submit tissue requests for ancillary studies. | nif-0000-00193 | SCR_007323 | nntc.org, nntc | 2026-08-04 09:41:50 | 11 | |||||
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Neuropathology of CTE and Delayed Effects of TBI: Toward In-Vivo Diagnostics Resource Report Resource Website |
Neuropathology of CTE and Delayed Effects of TBI: Toward In-Vivo Diagnostics (RRID:SCR_012951) | Neuropathology of CTE and Delayed Effects of TBI: Toward In-Vivo Diagnostics | portal, topical portal, research forum portal, disease-related portal, data or information resource | A multi-center and multi-disciplinary study designed to dramatically increase understanding of chronic traumatic encephalopathy (CTE) and other late effects of traumatic brain injury (TBI). Overlapping clinical features, postmortem pathologies and patterns of involvement exist in TBI, CTE, and Alzheimer''s disease pose challenges to accurate diagnosis. Premortem diagnosis of CTE is currently impossible. The neuropathological consequences of single mild or moderate-severe TBI and its relationship with CTE and known dementias are unclear. The proposed project will leverage extensive resources from an ongoing population-based prospective cohort study of brain aging (Adult Changes in Thought; ACT, n=2,305) which includes excellent medical, behavioral, and genetic characterization of a cohort (20% of whom have a history of mild-moderate TBI) in addition to state-of-the-art neuropathology workup upon death. Neuropathological study of TBI effects can begin immediately in the existing ACT autopsy sample (n=489, 20% with TBI exposure). Additional cohorts of TBI- exposed individuals will come from the Brain Injury Research Center at Mount Sinai (n=150 individuals with moderate-severe TBI), the University of Texas Southwestern (n=50 retired boxers with repetitive TBI exposure), and the National Football League (n=76 retired players with repetitive TBI exposure). All participants in the proposed study (ACT and other sites) will undergo uniform harmonized neurobehavioral assessment (chosen to maximize correspondence with existing large-scale TBI and dementia studies), MRI scan, and genomic analysis. Those individuals who expire during the course of the study will undergo ex-vivo neuroimaging and extensive neuropathological exam using state-of-the-art techniques (such as Histelide) designed to quantify tau and A�� in whole brain specimens. Only by examining postmortem pathology in a sample of individuals with varying levels of TBI exposure who are well characterized during life (as proposed herein) can postmortem pathology facilitate identification of in-vivo biomarkers that can act as diagnostic tools. This project represents the most systematic and scientifically rigorous effort to date to develop a more complete understanding of the long-term clinical and neuropathological sequelae of single and multiple TBI. | cognitive decline, health decline, dementia, symptom, incidence, prevalence, risk factor, causal role, multifocal tauopathy, neuropathology, neuroimaging, brain, biomarker, diagnosis, clinical | has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA | Chronic traumatic encephalopathy, Traumatic brain injury, Aging | nlx_156787 | SCR_012951 | Neuropathology of CTE and Late Effects of TBI: Toward In-Vivo Diagnostics, Neuropathology of Chronic Traumatic Encephalopathy (CTE) and Late Effects of Traumatic Brain Injury (TBI): Toward In-Vivo Diagnostics | 2026-08-04 09:43:06 | 0 | |||||||
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Northwestern CNADC Tissue Bank / Neuropathology Core Resource Report Resource Website |
Northwestern CNADC Tissue Bank / Neuropathology Core (RRID:SCR_013178) | biomaterial supply resource, brain bank, material resource, tissue bank | Tissue bank for collecting, cataloging and storing postmortem brain tissue samples from subjects with and without neurological disorders. Specimens are available for research on cognitive impairment, Alzheimer's, dementia and other disorders along with clinical data such as demographic information, health and family history and neuropsychological test scores. The bank provides services to distribute postmortem brain tissue and other samples to investigators for use in research that will provide qualitative and quantitative diagnostic information to physicians, families, and researchers. | brain tissue, brain, tissue, plasma, blood, dna, cerebral spinal fluid, paraformaldehyde-fixed, frozen, paraffin block, unfixed, late adult human, autopsy, post-mortem, clinical dementia rating scale, mini mental state examination, neuropathology, clinical data, alzheimer's disease, dementia, normal control, non-demented control, dementia with lewy body, frontotemporal lobar degeneration, pick disease, corticobasal degeneration, tauopathy, progressive supranuclear palsy, tangle-predominant senile dementia, amyotrophic lateral sclerosis, motor neuron disease, vascular dementia, mild cognitive impairment, research, brain bank, tissue |
is listed by: One Mind Biospecimen Bank Listing has parent organization: Northwestern University Cognitive Neurology and Alzheimers Disease Center |
Alzheimer's disease, Dementia, Dementia with Lewy body, Frontotemporal lobar degeneration, Pick disease, Corticobasal degeneration, Tauopathy, Progressive Supranuclear Palsy, Tangle-predominant senile dementia, Amyotrophic Lateral Sclerosis, Motor Neuron Disease, Vascular dementia, Mild cognitive impairment, Aging | NIA P30 AG13854 | Available to the research community | nlx_144054 | http://www.brain.northwestern.edu/mdad/neuropathology.html | SCR_013178 | Northwestern University Cognitive Neurology and Alzheimer's Disease Center Tissue/Neuropathology Core, Northwestern University CNADC Tissue/Neuropathology Core, Northwestern's Cognitive Neurology and Alzheimers Disease Center Tissue/Neuropathology Core, Northwestern Tissue/Neuropathology Core, Northwestern Neuropathology Core of CNADC, Northwestern Cognitive Neurology and Alzheimer's Disease Center Tissue/Neuropathology Core, Northwestern Cognitive Neurology Alzheimer's Disease Center Tissue/Neuropathology Core, Northwestern CNADC Tissue / Neuropathology Core, Northwestern University CNADC Tissue / Neuropathology Core | 2026-08-04 09:43:09 | 0 | |||||
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Djavad Mowafaghian Centre for Brain Health Resource Report Resource Website 1+ mentions |
Djavad Mowafaghian Centre for Brain Health (RRID:SCR_013149) | Brain Research Centre | topical portal, portal, data or information resource | Research facility for research on neurological and psychiatric disorders on the learning brain and the aging brain. The Centre utilizes a multidisciplinary approach to explore the causes and potential treatments of disorders like Alzheimer's disease, mental health and addiction, stroke and neurotrauma. The Centre focuses on translating research into patient care and therapies. | neurodegeneration, neurological disorder, mental disease, neuroscience, research, alzheimer's disease, parkinson's disease, amyotrophic lateral sclerosis, multiple sclerosis, mental health, addiction, stroke, neurotrauma, neuroimaging, genomics, peptide synthesis, purification, learning, pain, synaptic function, plasticity, traumatic brain injury, spinal cord injury, eye, brain, research, psychiatry, aging | has parent organization: University of British Columbia; British Columbia; Canada | Psychiatric disorder, Neurodegeneration, Neurological disorder, Alzheimer's disease, Parkinson's disease, Amyotrophic Lateral Sclerosis, Multiple Sclerosis, Addiction, Stroke, Neurotrauma, Aging, Learning, Pain, Traumatic brain injury | Public, Available to the research community | nlx_144253 | http://www.brain.ubc.ca/Home.htm | SCR_013149 | Brain Research Centre | 2026-08-04 09:43:09 | 1 | |||||
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HED Tags Resource Report Resource Website 1+ mentions |
HED Tags (RRID:SCR_014074) | HED | narrative resource, standard specification, data or information resource | Strategy guide for HED Annotation. Framework for systematically describing laboratory and real world events.HED tags are comma separated path strings. Organized in forest of groups with roots Event, Item, Sensory presentation, Attribute, Action, Participant, Experiment context, and Paradigm. Used for preparing brain imaging data for automated analysis and meta analysis. Applied to brain imaging EEG, MEG, fNIRS, multimodal mobile brain or body imaging, ECG, EMG, GSR, or behavioral data. Part of Brain Imaging Data Structure standard for brain imaging. | Data, structure, standard, EEG, brain, imaging, comma, separated, path, string, analysis, MEG, fNIRS, multimodal, ECG, EMG, GSR, behavioral, BRAIN Initiative |
is used by: NIMH Data Archive is used by: HeadIT is used by: OpenNeuro is recommended by: BRAIN Initiative has parent organization: University of California at San Diego; California; USA |
Swartz Foundation ; Army Research Laboratory Cooperative Agreement ; NIMH R01MH084819; NINDS R01 NS047293 |
PMID:27799907 | Free, Freely available | SCR_017630 | SCR_014074 | Hierarchical Event Descriptor Tags, Hierarchical Event Descriptor, HED, HED tags | 2026-08-04 09:43:19 | 7 | |||||
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FluoRender Resource Report Resource Website 100+ mentions |
FluoRender (RRID:SCR_014303) | data processing software, data analysis software, software resource, software application, data visualization software | Interactive rendering tool for confocal microscopy data visualization. Combines rendering of multi-channel volume data and polygon mesh data, where properties of each dataset can be adjusted independently and quickly. Designed for neurobiologists, allowing them to better visualize confocal data from fluorescently-stained brains, but it is also useful for other biological samples. Features include feature tracking, 3D measurement tools, multiple render modes for multi-channel confocal data, and volume paint selection and segmentation. | rendering tool, confocal microscopy data visualization, neurobiology, fluorescent stain, brain, bio.tools |
is used by: VVD Viewer is listed by: bio.tools is listed by: Debian has parent organization: University of Utah; Utah; USA |
Free, Available for download, Freely available | biotools:fluorender | https://bio.tools/fluorender | SCR_014303 | FluoRender Visualization | 2026-08-04 09:43:23 | 127 | |||||||
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Data Archive BRAIN Initiative Resource Report Resource Website 10+ mentions |
Data Archive BRAIN Initiative (RRID:SCR_017114) | DABI | storage service resource, data repository, data or information resource, service resource | Organize, Store, Disseminate, Analyze and Visualize Invasive Neurophysiology Data. Shared archive and resource for human invasive neurophysiology data that have been established by Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative along with software tools for data uploading, visualization and analysis. Users can view and query datasets through online interface but cannot access raw data. Platform utilizes centralized and federated model. Investigators may upload data to central archive or house it themselves. | shared, archive, human, invasive, neurophysiology, data, brain, neurotechnology, dataset, BRAIN Initiative |
is recommended by: National Library of Medicine is recommended by: BRAIN Initiative has parent organization: University of Southern California; Los Angeles; USA has parent organization: BRAIN Initiative |
BRAIN Initiative | Restricted | SCR_017114 | Data Archive Brain Initiative, DABI | 2026-08-04 09:44:05 | 14 | |||||||
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MeshView Resource Report Resource Website 10+ mentions |
MeshView (RRID:SCR_017222) | data access protocol, software resource, web service | Web application for real time 3D display of surface mesh data representing structural parcellations and generation of user defined cut planes from volumetric atlases. | real, time, 3D, display, surface, mesh, data, structural, parcellation, generation, defined, cut, plane, volumetric, atlas, brain |
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) is related to: LocaliZoom is related to: Allen Institute for Brain Science has parent organization: University of Oslo; Oslo; Norway works with: Waxholm Space Atlas of the Sprague Dawley Rat Brain works with: Allen Mouse Brain Reference Atlas works with: Waxholm Space |
European Union Horizon 2020 Human brain project | DOI:10.1371/journal.pone.0216796 | Free, Freely available | https://localiview.apps.ebrains.eu/, https://meshview-for-brain-atlases.readthedocs.io, https://github.com/Neural-Systems-at-UIO/MeshView-for-Brain-Atlases | SCR_017222 | MeshView for brain atlases | 2026-08-04 09:44:06 | 11 | ||||||
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Neuroreader Resource Report Resource Website 10+ mentions |
Neuroreader (RRID:SCR_017309) | NeuroreaderTM | data processing software, software application, image processing software, software resource | Software application as image segmentation tool. Brain volumetry assessment software. Processes MRI scans and provides self explanatory patient report with total brain volume, hippocampal volume and volumetric data on key segments of brain measured against healthy database. | Brain, volumetry, assessment | is affiliated with: Brainreader | PMID:26484924 | Restricted | https://brainreader.net/p/product/neuroreader | SCR_017309 | Neuro Reader, Neuroreader | 2026-08-04 09:44:08 | 11 | ||||||
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Knowing what you know (kwyk) - Bayesian Brain Parcellation Resource Report Resource Website |
Knowing what you know (kwyk) - Bayesian Brain Parcellation (RRID:SCR_017470) | kwyk | segmentation software, data processing software, software resource, software application, image analysis software | Software tool as deep neural network for predicting FreeSurfer segmentations of structural MRI volumes. This tool is implemented as both Docker and Singularity containers. Used for brain parcellation and uncertainty estimation. | Deep, neural, network, prediction, FreeSurfer, segmentation, structural, MRI, volume, brain, parcellation, uncertainty, estimation | is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) | Free, Available for download, Freely available | https://github.com/neuronets/kwyk | SCR_017470 | knowing what you know | 2026-08-04 09:44:10 | 0 | |||||||
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StimVision Resource Report Resource Website 1+ mentions |
StimVision (RRID:SCR_017457) | data processing software, data visualization software, software application, software resource | Software tool to facilitate tractography based deep brain stimulation (DBS) electrode targeting within patient specific stereotactic coordinate system used in operating room. | Tractography, deep, brain, stimulation, BRAIN Initiative | is recommended by: BRAIN Initiative | NIMH R01 MH102238; NIMH R01 MH106173 |
PMID:28653482 | SCR_017457 | Stim Vision, StimVision | 2026-08-04 09:44:09 | 1 | ||||||||
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The Decoding Toolbox Resource Report Resource Website 10+ mentions |
The Decoding Toolbox (RRID:SCR_017424) | TDT | data processing software, software application, software resource, data analysis software | Software Matlab toolbox for multivariate analysis of functional and structural MRI data. Software package for multivariate analyses of functional imaging data. | Multivariate, analysis, structural, MRI, data, functional, imaging, brain | German Ministry of Education and Research ; German Research Foundation |
PMID:25610393 | Free, Available for download, Freely available | SCR_017424 | 2026-08-04 09:44:13 | 13 | ||||||||
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MonkeyCBP Resource Report Resource Website 1+ mentions |
MonkeyCBP (RRID:SCR_017640) | MonkeyCBP | software toolkit, software resource, algorithm resource | Software toolbox for connectivity based parcellation of monkey brain. Integrated pipeline realizing tractography based brain parcellation with automatic processing and massive parallel computing. Highly automated process and high throughput performance supported by GPU option makes toolbox ready to be used by research community. | MonkeyCBP, Atlas, Parcellation Atlas, neuroimaging pipeline, brain, | is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) | Free, Freely available | SCR_017675 | http://www.nitrc.org/projects/monkey-cbp/ | SCR_017640 | Monkey Connectivity Based Parcellation; MonkeyCBP: A toolbox for connectivity-based parcellation of monkey brain | 2026-08-04 09:44:12 | 1 | ||||||
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Allen Software Development Kit Resource Report Resource Website 10+ mentions |
Allen Software Development Kit (RRID:SCR_018183) | AllenSDK | data processing software, software application, software resource, data analysis software | Software tool as code for processing and analyzing data in Allen Brain Atlas. Source code for reading and processing Allen Brain Atlas data. Allen SDK focuses on Allen Brain Observatory, Cell Types Database, and Mouse Brain Connectivity Atlas. | Data analysis, data processing, Allen Brain Atlas, data, brain |
is related to: Allen Brain Atlas is organization facet of: BICCN |
Free, Freely available | SCR_018192 | https://allensdk.readthedocs.io/en/latest/ | SCR_018183 | 2026-08-04 09:44:21 | 28 | |||||||
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BrainMaker Resource Report Resource Website 1+ mentions |
BrainMaker (RRID:SCR_017666) | data processing software, image reconstruction software, software resource, software application, image analysis software, 3d visualization software, data visualization software | Software tool to automatically align sections to visualize brains in 3D. Assists with cell mapping, cytoarchitectonics and other areas requiring characterization of neuronal circuitry to create comprehensive anatomical reference. Automatically creates full resolution, 3D reconstructions of entire brain or any organ from serial sections of whole slide images. Allows to view cells, structures, and lesions, locate neurons expressing particular gene or visualize axonal projections of specific neurons with full anatomical context. | BMF Bioscience, align, section, visualize, brain, 3D, cell, mapping, cytoarchitectonics, neural, circuitry, anatomical, reference, brain, organ, serial, slide, image | Restricted | SCR_017666 | 2026-08-04 09:44:11 | 1 | |||||||||||
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DOTS WM tract segmentation Resource Report Resource Website 100+ mentions |
DOTS WM tract segmentation (RRID:SCR_009459) | DOTS | segmentation software, data processing software, software resource, software application, image analysis software | A fast, scalable tool developed at the Johns Hopkins University to automatically segment the major anatomical fiber tracts within the human brain from clinical quality diffusion tensor MR imaging. With an atlas-based Markov Random Field representation, DOTS directly estimates the tract probabilities, bypassing tractography and associated issues. Overlapping and crossing fibers are modeled and DOTS can also handle white matter lesions. DOTS is released as a plug-in for the MIPAV software package and as a module for the JIST pipeline environment. They are therefore cross-platform and compatible with a wide variety of file formats. | magnetic resonance, diffusion tensor mr imaging, dti, fiber tract, brain |
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) is related to: MIPAV: Medical Image Processing and Visualization is related to: JIST: Java Image Science Toolkit has parent organization: Johns Hopkins University; Maryland; USA |
NIDA K25DA025356 | PMID:21718790 | Free | nlx_155605 | SCR_009459 | Diffusion-Oriented Tract Segmentation White Matter tract segmentation, Diffusion-Oriented Tract Segmentation | 2026-08-04 09:42:23 | 115 | |||||
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Baby Brain Toolkit Resource Report Resource Website |
Baby Brain Toolkit (RRID:SCR_009440) | BTK | data processing software, software resource, software application, image processing software, image analysis software, software toolkit | Software toolkit developed for the fbrain project that consists of several image processing tools: image reconstruction, image denoising, image segmentation, tractography etc., for a better understanding of fetal brain development. | computational neuroscience, magnetic resonance, fetus, brain, development, mri | is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) | ERC | PMID:23036854 | CeCILL license, v2 | nlx_155584 | SCR_009440 | BTK : Baby Brain Toolkit | 2026-08-04 09:42:23 | 0 | |||||
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UC Davis Alzheimers Disease Center - Resources Resource Report Resource Website |
UC Davis Alzheimers Disease Center - Resources (RRID:SCR_010699) | UCD ADC Resources | biomaterial supply resource, brain bank, material resource, tissue bank | THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. Support research in Alzheimer's disease (AD) offering pilot grants, recruitment of research subjects, access to database, tissue samples, and statistical and research study design consultation for investigators. The scientific effort of the program seeks to: promote research directed at understanding factors that influence the expression and progression of Alzheimer's disease; develop and maintain cohorts of carefully diagnosed and well characterized research subjects available for research studies on Alzheimer's disease and dementia; provide support to investigators in subject recruitment, clinical research, experimental design, and statistical analysis of data; and maintain a variety of samples (brain, DNA, serum) and an extensive electronic database suitable for developing new research and supporting existing programs. | brain, dna, serum, brain tissue, tissue |
is listed by: One Mind Biospecimen Bank Listing has parent organization: UC Davis Alzheimer's Disease Center |
Alzheimer's disease, Aging | State of California's Department of Public Health ; Martinez Veterans Health Administration ; NIA |
THIS RESOURCE IS NO LONGER IN SERVICE | nlx_82710 | SCR_010699 | University of California Davis Alzheimer's Disease Center - Resources | 2026-08-04 09:42:46 | 0 | |||||
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Brain Atlas Database of Japanese Monkey for WWW Resource Report Resource Website 1+ mentions |
Brain Atlas Database of Japanese Monkey for WWW (RRID:SCR_006104) | Brain Atlas Database of Japanese Monkey | data set, atlas, data or information resource, image collection | Atlas of magnetic resonance images and histological sections of a Japanese monkey brain, Rhesus monkey and human. The Brain Explorer allows for display, magnification, and comparison these images. Other formats include a collection of .jpg images, Quicktime VR (allow user to zoom in), and EmonV, a voxel viewer for MacOS X. | magnetic resonance image, histological section, brain, cerebellum, brain explorer, male, adult, neuroanatomy | has parent organization: RIO-DB - Research Information Database | Exclusive property of the AIST. Unauthorized reproduction or use of all or part of these materials is prohibited. http://riodb.ibase.aist.go.jp/copyrighte.html | nlx_151575 | SCR_006104 | Brain Atlas Database of Japanese Monkey for WWW. | 2026-08-04 09:41:30 | 1 | |||||||
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MICe - Mouse Imaging Centre Resource Report Resource Website 1+ mentions |
MICe - Mouse Imaging Centre (RRID:SCR_006145) | MICe | portal, topical portal, reference atlas, production service resource, service resource, atlas, data or information resource | A unique resource and comprehensive imaging facility combining the latest state-of-the-art digital medical imaging technologies for the characterization of mouse functional genomics. The goals of the Mouse Imaging Centre are: * To provide a variety of medical imaging technologies adapted to studying genetically modified mice. These technologies include magnetic resonance (MR) imaging, micro computed tomography (micro-CT), ultrasound biomicroscopy (UBM), and optical projection tomography (OPT). * To screen large numbers of mice for models of human diseases. * To image an individual mouse over time to observe development, disease progression and responses to experimental treatment. * To develop an exciting team of investigators with expertise in imaging techniques, computer science, engineering, imaging processing, developmental biology and mouse pathology. * To work by collaboration with researchers throughout the world. When we look for human diseases in the human population, we make extensive use of medical imaging. Therefore, it makes sense to have available the same imaging capabilities as we investigate mice for models of human disease. The Mouse Imaging Centre (MICe) has developed high field magnetic resonance imaging microscopy, ultrasound biomicroscopy, micro computed tomography, and optical techniques. With these imaging tools, MICe is screening randomly mutagenized mice to look for phenotypes that represent human diseases and is taking established human disease models in mice and using imaging to follow the progression of disease and response to treatment over time. It is clear that imaging has a major contribution to make to phenotyping genetic variants and to characterizing mouse models. MICe is staffed by an exciting new team of about 30 investigators with expertise in imaging techniques, computer science, engineering, imaging processing, developmental biology and mouse pathology. The Mouse Imaging Centre (MICe) is not a fee-for-service facility but works through collaborations. Services include: * Projects involving MicroCT are available as a fee for service. * We will eventually move to the same model above with MRI. * Ultrasound Biomicroscopy is used for cardiac, embryo and cancer studies and is available as fee for service at $100 per study or in some cases on a collaborative basis. * Optical Projection Tomography has only limited availability on a collaborative basis. Mouse Atlas As our images are inherently three-dimensional, we will be able to make quantitative measures of size and volume. With this in mind, we are developing a mouse atlas showing the normal deviation of organ sizes. This atlas is an important resource for biologists as it has the potential to eliminate the need to sacrifice as many controls when making comparisons with mutants. Mouse Atlas Examples: * Variational Mouse Brain Atlas * Cerebral Vascular Atlas of the CBA Mouse * Neuroanatomy Atlas of the C57Bl/6j Mouse * Vascular Atlas of the Developing Mouse Embryo * Micro-CT E15.5 Mouse Embryo Atlas | imaging, functional genomics, mutant mouse, mri, micro computed tomography, ultrasound biomicroscopy, optical projection tomography, phenotype, genetic variant, brain, image | has parent organization: Toronto Centre for Phenogenomics | Human disease | Burroughs Wellcome Fund ; Canada Foundation for Innovation ; Canada Research Chairs ; Canadian Institutes of Health Research ; National Cancer Institute of Canada ; NIH ; Ontario Innovation Trust ; Ontario Research and Development Challenge Fund ; commercial partners |
nlx_151635 | SCR_006145 | Mouse Imaging Centre, Mouse Imaging Center, Mouse Imaging Centre (MICe) | 2026-08-04 09:41:31 | 3 |
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