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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
False Discovery Rate Weighted
 
Resource Report
Resource Website
1+ mentions
False Discovery Rate Weighted (RRID:SCR_009473) False Discovery Rate Weighted software application, software resource Simple and efficient, this application performs the Weighted False Discovery Rate procedure of Benjamini and Hochberg (1997) to correct for multiple testing. The good think is that you can test virtually any number of p-values (even millions) obtained with any test-statistics for any data set. The bonus is that you can assign a-priori weights to give a better chance to those variables that you deem important. In practice, this procedure is powerful only with a relatively small number of p-values. magnetic resonance is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) nlx_155620 SCR_009473 2026-08-09 09:05:02 1
LDDMM
 
Resource Report
Resource Website
10+ mentions
LDDMM (RRID:SCR_009590) LDDMM software application, software resource Software application which aims to assign metric distances on the space of anatomical images in Computational Anatomy thereby allowing for the direct comparison and quantization of morphometric changes in shapes. As part of these efforts the Center for Imaging Science at Johns Hopkins University developed techniques to not only compare images, but also to visualize the changes and differences. For additional information please refer to: Faisal Beg, Michael Miller, Alain Trouve, and Laurent Younes. Computing Large Deformation Metric Mappings via Geodesic Flows of Diffeomorphisms. International Journal of Computer Vision, Volume 61, Issue 2; February 2005. M.I. Miller and A. Trouve and L. Younes, On the Metrics and Euler-Lagrange Equations of Computational Anatomy, Annual Review of biomedical Engineering, 4:375-405, 2002. Software developed with support from National Institutes of Health NCRR grant P41 RR15241. analyze, c++, console (text based), linux, microsoft, magnetic resonance, posix/unix-like, shape analysis, win32 (ms windows), windows is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Johns Hopkins University; Maryland; USA
nlx_155780 http://www.nitrc.org/projects/lddmm-volume SCR_009590 Large Deformation Diffeomorphic Metric Mapping 2026-08-09 09:05:24 31
GMAC: A Matlab toolbox for spectral Granger causality analysis of fMRI data
 
Resource Report
Resource Website
1+ mentions
GMAC: A Matlab toolbox for spectral Granger causality analysis of fMRI data (RRID:SCR_009581) GMAC software toolkit, software resource Open-source software toolbox implemented multivariate spectral Granger Causality Analysis for studying brain connectivity using fMRI data. Available features are: fMRI data importing, network nodes definition, time series preprocessing, multivariate autoregressive modeling, spectral Granger causality indexes estimation, statistical significance assessment using surrogate data, network analysis and visualization of connectivity results. All functions are integrated into a graphical user interface developed in Matlab environment. Dependencies: Matlab, BIOSIG, SPM, MarsBar. analyze, computational neuroscience, connectivity analysis, matlab, magnetic resonance, nifti, os independent, fmri, connectivity, granger causality, network analysis is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Polytechnic University of Milan; Milan; Italy
NIH Blueprint for Neuroscience Research PMID:22925560 nlx_155764 http://www.nitrc.org/projects/gmac_2012 http://selene.bioing.polimi.it/BBBlab/GMAC/ SCR_009581 Granger Multivariate Autoregressive Connectivity 2026-08-09 09:05:04 1
TAGGER
 
Resource Report
Resource Website
50+ mentions
TAGGER (RRID:SCR_009419) software application, software resource Software application (entry from Genetic Analysis Software) gene, genetic, genomic, web-based is listed by: Genetic Analysis Software
is listed by: SoftCite
nlx_154669 SCR_009419 2026-08-09 09:05:19 93
SPLINK
 
Resource Report
Resource Website
10+ mentions
SPLINK (RRID:SCR_009414) software application, software resource Software application for linkage analysis using affected sib pairs (entry from Genetic Analysis Software) gene, genetic, genomic, c++, unix, sunos, ms-dos is listed by: Genetic Analysis Software nlx_154659 http://www-gene.cimr.cam.ac.uk/clayton/software/ SCR_009414 affected Sib Pairs LINKage analysis 2026-08-09 09:05:02 49
SSAHASNP
 
Resource Report
Resource Website
1+ mentions
SSAHASNP (RRID:SCR_009415) SSAHASNP software application, software resource A polymorphism detection tool that detects homozygous SNPs and indels by aligning shotgun reads to the finished genome sequence. Highly repetitive elements are filtered out by ignoring those kmer words with high occurrence numbers. For those less repetitive or non-repetitive reads, we place them uniquely on the reference genome sequence and find the best alignment according to the pair-wise alignment score if there are multiple seeded regions. From the best alignment, SNP candidates are screened, taking into account the quality value of the bases with variation as well as the quality values in the neighbouring bases, using neighbourhood quality standard (NQS). For insertions/deletions, we check if the same indel is mapped by more than one read, ensuring the detected indel with high confidence. (entry from Genetic Analysis Software) gene, genetic, genomic is listed by: Genetic Analysis Software nlx_154661 SCR_009415 Sequence Search and Alignment by Hashing Algorithm for SNP detection 2026-08-09 09:05:11 4
BrainGraph Editor
 
Resource Report
Resource Website
1+ mentions
BrainGraph Editor (RRID:SCR_009536) BrainGraph Editor software application, software resource A JAVA application designed to create taxonomies or hierarchies in order to classify and organize information. gnome, information resource, information specification, java, kde, ontology, os independent, visualization, win32 (ms windows), taxonomy, hierarchy, classify, organize is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Laboratory of Neuro Imaging
BIRN License, LONI Software License nlx_155713 http://www.nitrc.org/projects/braingrpheditor SCR_009536 2026-08-09 09:05:03 3
SEQUENCE LD/SEQUENCE LDHOT
 
Resource Report
Resource Website
SEQUENCE LD/SEQUENCE LDHOT (RRID:SCR_009379) software application, software resource Software program that analyzes sequence data. It obtains an approximation to the likelihood of a summary of the data (as such it can be thought of as a marginal likelihood approach). It does not use all the information in the data, but computationally it can be substantially more efficient than the full-likelihood methods (and hence able to analyze larger data sets). (entry from Genetic Analysis Software) gene, genetic, genomic is listed by: Genetic Analysis Software nlx_154614 http://www.maths.lancs.ac.uk/~fearnhea/Software.html SCR_009379 2026-08-09 09:05:01 0
SDMINP
 
Resource Report
Resource Website
SDMINP (RRID:SCR_009377) SDMINP software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 24,2023. Software program for fast calculation of empirical and adjusted p-values for correlated and uncorrelated hypotheses in multiple testing experiments. It is based on the Free Step-Down Resampling Method for controlling the Family Wise Error Rate, originally proposed by Westfall and Young (1993), and implements a variation of the efficient algorithm of Ge et al. (2003), in which the originally necessary re-sampling effort was reduced considerably and the method made computationally more feasible. The program is independent of the underlying test statistic and works with provided observed and permutation test statistics. (entry from Genetic Analysis Software) gene, genetic, genomic, python 2.3.5, unix, linux, ms-windows is listed by: Genetic Analysis Software THIS RESOURCE IS NO LONGER IN SERVICE nlx_154612 http://www.dkfz.de/SDMinP/ SCR_009377 Step-Down MIN P-value 2026-08-09 09:05:10 0
SPIP
 
Resource Report
Resource Website
100+ mentions
SPIP (RRID:SCR_009410) software application, software resource Software application that simulate pedigrees and genetic data in age-structured populations (entry from Genetic Analysis Software) gene, genetic, genomic, c is listed by: Genetic Analysis Software nlx_154657 SCR_009410 Simulate Pedigree In Population 2026-08-09 09:05:19 433
SPLAT
 
Resource Report
Resource Website
10+ mentions
SPLAT (RRID:SCR_009411) SPLAT software application, software resource Software application that can calculate virtually any linkage test statistic under several sib pair study designs: affected, discordant, unaffected, and pairs defined by threshold values for quantitative traits, such as extreme discordant sib pairs. It uses the EM algorithm to compute maximum likelihood estimates of sharing (subject to any user-specified domain restrictions or null hypotheses) and then plots lod scores versus chromosomal position. It includes a novel grid scanning capability that enables simultaneous visualization of multiple test statistics. Phenotype definitions can be modified without recalculating inheritance vectors, thereby providing considerable analytical flexibility. (entry from Genetic Analysis Software), THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, genetic, genomic, c++, qt, unix, sunos, linux, macos, ms-windows, (2000/xp) is listed by: Genetic Analysis Software THIS RESOURCE IS NO LONGER IN SERVICE nlx_154658 SCR_009411 Sib Pair Linkage Analysis Testing 2026-08-09 09:05:01 19
R/METASIM
 
Resource Report
Resource Website
1+ mentions
R/METASIM (RRID:SCR_009370) software application, software resource An R package that uses an individual-based approach to simulate distributions of genotypes that result from arbitrary within and among population demographies (including extinction/recolonization). These distributions can be used to test new or existing population-genetics summary statistics or develop null distributions under various demographies. (entry from Genetic Analysis Software) gene, genetic, genomic, r, c++, unix, ms-windows, macos is listed by: Genetic Analysis Software nlx_154592 http://linum.cofc.edu/software.html SCR_009370 METApopulation SIMulation 2026-08-09 09:05:01 1
SPERM
 
Resource Report
Resource Website
10+ mentions
SPERM (RRID:SCR_009409) software application, software resource Software application for analysis of sperm typing data. (entry from Genetic Analysis Software), THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, genetic, genomic, fortran77 is listed by: Genetic Analysis Software THIS RESOURCE IS NO LONGER IN SERVICE nlx_154656 SCR_009409 2026-08-09 09:05:10 16
Solar Eclipse Imaging Genetics tools
 
Resource Report
Resource Website
10+ mentions
Solar Eclipse Imaging Genetics tools (RRID:SCR_009645) Solar Eclipse Imaging Genetics tools software application, software resource Software tools optimized for performing univariate and multivariate imaging genetics analyses while providing practical correction strategies for multiple testing. The goal of this project is to merge two important research directions in modern science, genetics and neuroimaging. This entails combining modern statistical genetic methods and quantitative phenotyping performed with high dimensional neuroimaging modalities. So far, however, standard imaging tools are unable to deal with large-scale genetics data, and standard genetics tools, in turn, are unable to accommodate large size and binary format of the image data. Their focus is to create imaging genetics tools for classical genetic and epigenetic epidemiological analyses such as heritability, pleiotropy, quantitative trait loci (QTL) and genome-wide association (GWAS), gene expression, and methylation analyses optimized for traits derived from structural and functional brain imaging data c++, genetic association, genomic analysis, gifti, imaging genomics, linux, loni pipeline, macos, microsoft, nifti, posix/unix-like, snp, gene, windows, windows xp, genetics, neuroimaging, heritability, pleiotropy, quantitative trait loci, genome-wide association, gene expression, methylation, trait, structural neuroimaging, functionalneuroimaging, brain imaging is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Free, Non-commercial, Open Software License, v3, Http://www.nitrc.org/include/glossary.php#552 nlx_155966 SCR_009645 2026-08-09 09:05:14 14
SNPALYZE
 
Resource Report
Resource Website
50+ mentions
SNPALYZE (RRID:SCR_009401) software application, software resource Software application (entry from Genetic Analysis Software) gene, genetic, genomic, ms-windows, (98/me/nt4.0/2000/xp) is listed by: Genetic Analysis Software nlx_154640 SCR_009401 2026-08-09 09:05:10 78
Generalized PPI Toolbox
 
Resource Report
Resource Website
50+ mentions
Generalized PPI Toolbox (RRID:SCR_009489) software toolkit, software resource An automated toolbox for a generalized form of psychophysiological interactions for SPM and FSFAST. The automated toolbox can do the following: (a1) produce identical results to the current implementation in SPM (a2) use the current implementation of PPI in SPM but using the regional mean instead of the eigenvariate (a3) use a generalized form that allows a PPI for each task to be in the same model using either the regional mean of eigenvariate (b) create the model using the output of one of the (a) options and the first level design (c) estimate the model (/results directory) (d) compute the contrasts specified. magnetic resonance, psychophysiological interaction, fmri, neuroimaging, automated toolbox, spm, fsfast is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Acknowledgement requested, Available for download nlx_155636 SCR_009489 Generalized Psychophysiological Interaction Toolbox 2026-08-09 09:05:12 56
Scirus - for scientific information only
 
Resource Report
Resource Website
10+ mentions
Scirus - for scientific information only (RRID:SCR_010657) Scirus service resource, software resource Science-specific search engine with over 575 million scientific items indexed at last count (May 2013), it allows researchers to search for not only journal content but also scientists'' homepages, courseware, pre-print server material, patents and institutional repository and website information. Scirus helps you quickly locate scientific information on the Web: * Filters out non-scientific sites. For example, if you search on REM, Google finds the rock group - Scirus finds information on sleep, among other things * Finds peer-reviewed articles such as PDF and PostScript files, which are often invisible to other search engines. * Searches the most comprehensive combination of web information, preprint servers, digital archives, repositories and patent and journal databases. Scirus goes deeper than the first two levels of a Web site, thereby revealing much more relevant information. Scirus has proved so successful at locating science-specific results on the Web that the Search Engine Watch Awards voted Scirus ''Best Specialty Search Engine'' in 2001 and 2002 and ''Best Directory or Search Engine Website'' WebAward from Web Marketing Association in 2004, 2005, 2006 and 2007. Give your Web site greater functionality and enhance the experience of your users, by adding Scirus to your home page for free. Scirus uses the latest in search engine technology to pinpoint precise scientific information that other search engines can not reach, including pdf files and peer reviewed articles. Make your Web site more visible to the scientific community, by submitting it for inclusion on Scirus. You will increase the chance of scientists finding your site when looking for information and you could increase your visitor rate. training tools, search engine, scientific, scholarly, technical, medical, report, peer-reviewed, article, patent, pre print, journal, plugin is listed by: 3DVC Free nlx_68864 SCR_010657 2026-08-09 09:05:39 28
SMOOTH
 
Resource Report
Resource Website
50+ mentions
SMOOTH (RRID:SCR_009398) software application, software resource Software tool that recognises and removes the most unrealistic data pointsfor the construction of accurate linkage maps, which is not so much depending on the quality of the mapping software, but mostly on the marker data quality. Missing values and scoring errors can severely influence the calculated marker order. This software was used to construct the 10,000 marker potato map. The removal of improbable data point is a good medicine for linkage maps, that is not easily overdosed. One error is more harmfull than ten missing values. The software was never intended as user-friendly software. In these days it would be more useful to re-do the programming of the pascal source code into a perl script. Anyone who takes the initiative to generate such a script is welcomed to contact the authors. SMOOTH works best in close cooperation with mapping algorithm RECORD (entry from Genetic Analysis Software) gene, genetic, genomic, pascal, ms-dos is listed by: Genetic Analysis Software nlx_154636 http://www.plantbreeding.wur.nl/UK/software_smooth.html SCR_009398 2026-08-09 09:05:10 60
SIMULATE
 
Resource Report
Resource Website
10+ mentions
SIMULATE (RRID:SCR_009391) software application, software resource Software program to simulate genotypes in family members for a map of linked markers unlinked to a given affection status locus. the output is ready for analysis with UNKNOWN, ISIM, LSIM, or MSIM of the SLINK package. (entry from Genetic Analysis Software) gene, genetic, genomic, pascal, ms-dos, vms, unix, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154630, biotools:simulate https://bio.tools/simulate SCR_009391 2026-08-09 09:05:01 12
SIMUPOP
 
Resource Report
Resource Website
10+ mentions
SIMUPOP (RRID:SCR_009392) software application, software resource A forward-based population genetics simulation program capable of simulating very complex evolution processes on large (think of millions) populations. Major features include variable population size; many built-in and hybrid (write in python) mutation, migration, selection models. simuPOP can be extended in Python so there is no limit on what you can do with it. (entry from Genetic Analysis Software) gene, genetic, genomic, c++, (provided as python libraries) is listed by: Genetic Analysis Software nlx_154631 https://pypi.python.org/pypi/simuPOP http://bp6.stat.rice.edu:8080/simuPOP/ SCR_009392 2026-08-09 09:05:10 26

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