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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
NeuroLex
 
Resource Report
Resource Website
10+ mentions
NeuroLex (RRID:SCR_005402) NeuroLex data or information resource, narrative resource, wiki A freely editable semantic wiki for community-based curation of the terms used in Neuroscience. Entries are curated and eventually incorporated into the formal NIFSTD ontology. NeuroLex also includes a Resource branch for community members to freely add neuroscience relevant resources that do not become part of NIFSTD ontology but rather make up the NIF Registry. As part of the NIF, we provide a simple search interface to many different sources of neuroscience information and data. To make this search more effective, we are constructing ontologies to help organize neuroscience concepts into category hierarchies, e.g., neuron is a cell. These categories provide the means to perform more effective searches and also to organize and understand the information that is returned. But an important adjunct to this activity is to clearly define all of the terms that we use to describe our data, e.g., anatomical terms, techniques, organism names. Because wikis provide an easy interface for communities to contribute their knowledge, we started the NeuroLex. behavioral activity, behavioral paradigm, brain region, cell, neuron, disease, molecule, nervous system function, subcellular part, resource type, quality, brain, neuroscience, biological process, cellular anatomy, anatomy, subcellular, subcellular anatomy, organism, neurological disorder, neurologic disease, dysfunction, atlas application, knowledge environment, php, web service, rdf, knowledge management, neuroanatomy, ontology, semantics, lexicon is used by: MicroDraw
is listed by: OMICtools
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: Program on Ontologies of Neural Structures
is related to: NIFSTD
is related to: neuroelectro
is related to: Whole Brain Catalog
is related to: Linked Neuron Data
is related to: SciCrunch Registry
is related to: InterLex
has parent organization: Neuroscience Information Framework
has parent organization: International Neuroinformatics Coordinating Facility
is parent organization of: Integrated
is parent organization of: Common Upper Mammalian Brain Ontology
is parent organization of: SciCrunch Registry
Neuroscience Information Framework PMID:24009581 Creative Commons Attribution License, v3 Unported OMICS_01703, nlx_144511 http://www.nitrc.org/projects/incf_neurolex-w SCR_005402 NeuroLex.org 2026-09-19 12:50:53 17
BioExtract
 
Resource Report
Resource Website
10+ mentions
BioExtract (RRID:SCR_005397) BioExtract service resource An open, web-based system designed to aid researchers in the analysis of genomic data by providing a platform for the creation of bioinformatic workflows. Scientific workflows are created within the system by recording tasks performed by the user. These tasks may include querying multiple, distributed data sources, saving query results as searchable data extracts, and executing local and web-accessible analytic tools. The series of recorded tasks can then be saved as a reproducible, sharable workflow available for subsequent execution with the original or modified inputs and parameter settings. Integrated data resources include interfaces to the National Center for Biotechnology Information (NCBI) nucleotide and protein databases, the European Molecular Biology Laboratory (EMBL-Bank) non-redundant nucleotide database, the Universal Protein Resource (UniProt), and the UniProt Reference Clusters (UniRef) database. The system offers access to numerous preinstalled, curated analytic tools and also provides researchers with the option of selecting computational tools from a large list of web services including the European Molecular Biology Open Software Suite (EMBOSS), BioMoby, and the Kyoto Encyclopedia of Genes and Genomes (KEGG). The system further allows users to integrate local command line tools residing on their own computers through a client-side Java applet. nucleotide sequence, protein sequence, viridiplantae, viridiplantae protein, nucleotide, sequence, protein, viridiplantae, workflow, software, database, bioinformatics, platform, genome, genomic analysis, analytic tool is listed by: OMICtools
is listed by: SoftCite
is related to: NCBI Nucleotide
is related to: NCBI Protein Database
is related to: UniProt
is related to: UniRef
is related to: EMBOSS
is related to: BioMoby
is related to: KEGG
has parent organization: Indiana University; Indiana; USA
has parent organization: University of South Dakota; South Dakota; USA
NSF 0090732;
NSF IOS-1126481
PMID:21546552
PMID:20865520
PMID:20150665
PMID:20054995
OMICS_01138 SCR_005397 BioExtract Server 2026-09-19 12:50:53 12
KGGSeq
 
Resource Report
Resource Website
50+ mentions
KGGSeq (RRID:SCR_005311) KGGSeq software resource A biological Knowledge-based mining platform for Genomic and Genetic studies using Sequence data. The software platform, constituted of bioinformatics and statistical genetics functions, makes use of valuable biologic resources and knowledge for sequencing-based genetic mapping of variants / genes responsible for human diseases / traits. It facilitates geneticists to fish for the genetic determinants of human diseases / traits in the big sea of DNA sequences. KGGSeq has paid attention to downstream analysis of genetic mapping. The framework was implemented to filter and prioritize genetic variants from whole exome sequencing data. genomic, genetic, sequence, mutation, exome sequencing, disease, gene, variant, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
Monogenic disorder, Cancer PMID:22241780 biotools:kggseq, OMICS_02260 https://bio.tools/kggseq SCR_005311 KGGSeq: A biological Knowledge-based mining platform for Genomic and Genetic studies using Sequence data 2026-09-19 12:50:51 58
SOAPindel
 
Resource Report
Resource Website
10+ mentions
SOAPindel (RRID:SCR_005272) SOAPindel software resource Software focusing on calling indels from the next-generation paired-end sequencing data. is listed by: OMICtools PMID:22972939 OMICS_00099 SCR_005272 2026-09-19 12:50:50 44
PING
 
Resource Report
Resource Website
50+ mentions
PING (RRID:SCR_005394) PING software resource Software program for probabilistic inference of ChIP-Seq using an empirical Bayes mixture model approach. clustering, sequencing, statistics, visualization, chip-seq, short-read is listed by: OMICtools
has parent organization: Bioconductor
Artistic License v2 OMICS_00513 http://www.nitrc.org/projects/ping SCR_005394 Probabilistic inference for Nucleosome Positioning, PING - Probabilistic inference for Nucleosome Positioning with MNase-based or Sonicated Short-read Data 2026-09-19 12:50:52 85
RSeQC
 
Resource Report
Resource Website
1000+ mentions
RSeQC (RRID:SCR_005275) RSeQC data analysis software, data processing software, sequence analysis software, software application, software resource Software package to comprehensively evaluate different aspects of RNA-seq experiments, such as sequence quality, GC bias, polymerase chain reaction bias, nucleotide composition bias, sequencing depth, strand specificity, coverage uniformity and read distribution over the genome structure. RSeQC takes both SAM and BAM files as input, which can be produced by most RNA-seq mapping tools as well as BED files, which are widely used for gene models. python, qc, rna-seq, high throughput sequencing is listed by: OMICtools PMID:22743226 OMICS_01235 SCR_005275 rseqc - RNA-seq quality control package 2026-09-19 12:50:50 1456
MuGeX
 
Resource Report
Resource Website
MuGeX (RRID:SCR_005306) MuGeX service resource Service that automatically extracts mutation-gene pairs from MEDLINE abstracts for a given disease. disease, gene, mutation is listed by: OMICtools
is related to: MEDLINE
has parent organization: Sabanci University; Istanbul; Turkey
PMID:18172928 Acknowledgement requested OMICS_01189 SCR_005306 MuGeX - Mutation Gene Extractor, Mutation Gene Extractor 2026-09-19 12:50:51 0
Scripture
 
Resource Report
Resource Website
10+ mentions
Scripture (RRID:SCR_005269) Scripture software resource Software for transcriptome reconstruction that relies solely on RNA-Seq reads and an assembled genome to build a transcriptome ab initio. The statistical methods to estimate read coverage significance are also applicable to other sequencing data. Scripture also has modules for ChIP-Seq peak calling. transcriptome, rna-seq read, genome sequence, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Alt Event Finder
has parent organization: Broad Institute
PMID:20436462 biotools:scripture, OMICS_01265 https://bio.tools/scripture SCR_005269 2026-09-19 12:50:50 11
Hmmer
 
Resource Report
Resource Website
5000+ mentions
Hmmer (RRID:SCR_005305) HMMER analysis service resource, data analysis service, data analysis software, data processing software, production service resource, service resource, software application, software resource Tool for searching sequence databases for homologs of protein sequences, and for making protein sequence alignments. It implements methods using probabilistic models called profile hidden Markov models (profile HMMs). Compared to BLAST, FASTA, and other sequence alignment and database search tools based on older scoring methodology, HMMER aims to be significantly more accurate and more able to detect remote homologs because of the strength of its underlying mathematical models. In the past, this strength came at significant computational expense, but in the new HMMER3 project, HMMER is now essentially as fast as BLAST. homolog, protein sequence, source code, FASEB list is used by: Mantis
is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: SoftCite
is related to: VectorBase
has parent organization: Janelia Research
Howard Hughes Medical Institute PMID:21593126
DOI:10.1093/bioinformatics/14.9.755
OMICS_00996, nlx_144358 https://sources.debian.org/src/hmmer/ SCR_005305 HMMER - biosequence analysis using profile hidden Markov models 2026-09-19 12:50:51 9520
SpliceSeq
 
Resource Report
Resource Website
100+ mentions
SpliceSeq (RRID:SCR_005267) SpliceSeq data analysis software, data processing software, software application, software resource A Java application to investigate alternative mRNA splicing patterns in data from high-throughput mRNA sequencing studies. Sequence reads are mapped to splice graphs that unambiguously quantify the inclusion level of each exon and splice junction. The graphs are then traversed to predict the protein isoforms that are likely to result from the observed exon and splice junction reads. UniProt annotations are mapped to each protein isoform to identify potential functional impacts of alternative splicing. This tool may be used on a single RNASeq sample to identify genes with multiple spliceforms, on a pair of samples to identify differential splicing between the two, or on groups of samples to identify statistically significant group level differences in splicing patterns. SpliceSeq can be run from the install page as a java web start application to explore the sequencing data on their server or can be installed locally to analyze your own mRNA-Seq data. rna-seq, mrna splicing pattern is listed by: OMICtools
has parent organization: University of Texas MD Anderson Cancer Center
OMICS_01267 SCR_005267 2026-09-19 12:50:50 179
SPLITREAD
 
Resource Report
Resource Website
1+ mentions
SPLITREAD (RRID:SCR_005264) SPLITREAD software resource Software for detecting INDELs (small insertions and deletion with size less than 50bp) as well as large deletions that are within the coding regions from the exome sequencing data. It also can be applied to the whole genome sequencing data. deletion, insertion, indel, genome, exome is listed by: OMICtools
is related to: drFAST
is related to: mrFAST
is related to: mrsFAST
is related to: VariationHunter
is related to: NovelSeq
is related to: mrCaNaVaR
has parent organization: SourceForge
OMICS_00323 SCR_005264 SPLITREAD - Split read based INDEL/SV Caller 2026-09-19 12:50:50 3
bioKepler
 
Resource Report
Resource Website
1+ mentions
bioKepler (RRID:SCR_005385) bioKepler software resource A Comprehensive Bioinformatics Scientific Workflow Module for Distributed Analysis of Large-Scale Biological Data that is distributed on top of the core Kepler scientific workflow system. module, bioinformatics, workflow, next-generation sequencing is listed by: OMICtools
is related to: Kepler
is related to: Molecular Dynamics Workflow (BioKepler)
NSF DBI-1062565 Acknowledgement requested OMICS_01139 SCR_005385 2026-09-19 12:50:52 2
Hydra
 
Resource Report
Resource Website
100+ mentions
Hydra (RRID:SCR_005260) Hydra software resource Software that detects structural variation (SV) breakpoints by clustering discordant paired-end alignments whose signatures corroborate the same putative breakpoint. Hydra can detect breakpoints caused by all classes of structural variation. Moreover, it was designed to detect variation in both unique and duplicated genomic regions; therefore, it will examine paired-end reads having multiple discordant alignments. Hydra does not attempt to classify SV breakpoints based on the mapping distances and orientations of each breakpoint cluster, it merely detects and reports breakpoints. This is an intentional decision, as it was observed that in loci affected by complex rearrangements, the type of variant suggested by the breakpoint signature is not always correct. Hydra does report the orientations, distances, number of supporting read-pairs, etc., for each breakpoint. It is suggested that downstream methods be used to classify variants based on the genomic features that they overlap and the co-occurrence of other breakpoints. For example, they developed BEDTools for exactly this purpose and the breakpoints reported by Hydra are in the BEDPE format used by BEDTools. Future releases of Hydra will include scripts that assist in the classification process. structural variation, genome, genomic, breakpoint, c++, cnv, pem, paired-end, segmental duplication, rearrangement is listed by: OMICtools
is listed by: SoftCite
is related to: BEDTools
has parent organization: Google Code
has parent organization: University of Virginia; Virginia; USA
OMICS_00318 SCR_005260 hydra-sv 2026-09-19 12:50:50 119
becas
 
Resource Report
Resource Website
10+ mentions
becas (RRID:SCR_005337) data access protocol, service resource, software resource, web service Web application, API and widget able to recognize and annotate biomedical concepts in text.Provides annotations for isolated, nested and intersected entities.Identifies concepts from multiple semantic groups, providing preferred names and enriching them with references to public knowledge resources. Annotation, biomedical concept recognition, annotate biomedical concepts, text, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Aveiro; Aveiro; Portugal
Free, Freely available biotools:becas, OMICS_01173 https://bioinformatics.ua.pt/software/becas/, https://bio.tools/becas SCR_005337 2026-09-19 12:50:51 12
MiRPara
 
Resource Report
Resource Website
10+ mentions
MiRPara (RRID:SCR_005294) miRPara software resource A SVM (support vector machine-based software tool for prediction of most probable microRNA coding regions in genome scale sequences. microrna, prediction, mirbase, novel, support vector machine, mirna, dicer, ago, coding region, genome sequence, high throughputut sequencing is listed by: OMICtools
has parent organization: Google Code
PMID:21504621 GNU General Public License, v3, Acknowledgement requested OMICS_00380 SCR_005294 mirpara - know and novel miRNA prediction software 2026-09-19 12:50:51 25
CHANCE
 
Resource Report
Resource Website
10+ mentions
CHANCE (RRID:SCR_005330) CHANCE software resource A standalone software package for ChIP-seq quality control and protocol optimization. is listed by: OMICtools OMICS_00429 SCR_005330 CHiP-seq ANalytics and Confidence Estimation 2026-09-19 12:50:51 13
NCBO Annotator
 
Resource Report
Resource Website
1+ mentions
NCBO Annotator (RRID:SCR_005329) NCBO Annotator data access protocol, production service resource, service resource, software resource, web service A Web service that annotates textual metadata (e.g. journal abstract) with relevant ontology concepts. NCBO uses this Web service to annotate resources in the NCBO Resource Index. They also provide this Web service as a stand-alone service for users. This Web service can be accessed through BioPortal or used directly in your software. Currently, the annotation workflow is based on syntactic concept recognition (using concept names and synonyms) and on a set of semantic expansion algorithms that leverage the semantics in ontologies (e.g., is_a relations). Their service methodology leverages ontologies to create annotations of raw text and returns them using semantic web standards. ontology, annotation, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: STOP
has parent organization: BioPortal
has parent organization: National Centers for Biomedical Computing
has parent organization: Stanford University; Stanford; California
NHGRI U54 HG004028 PMID:19483092 biotools:bioportal, nlx_144389, OMICS_01172 https://bio.tools/bioportal SCR_005329 Open Biomedical Annotator, NCBO BioPortal Annotator 2026-09-19 12:50:51 6
Assembly Likelihood Estimator
 
Resource Report
Resource Website
Assembly Likelihood Estimator (RRID:SCR_005326) ALE software resource Software using a probabalistic framework for determining the likelihood of an assembly given the data (raw reads) used to assemble it. It allows for the rapid discovery of errors and comparisons between similar assemblies. standalone software, c, python is listed by: OMICtools
has parent organization: DOE Joint Genome Institute
has parent organization: Cornell University; New York; USA
PMID:23303509 Open-source license OMICS_04067 https://github.com/sc932/ALE SCR_005326 ALE: Assembly Likelihood Estimator 2026-09-19 12:50:51 0
CoPub
 
Resource Report
Resource Website
1+ mentions
CoPub (RRID:SCR_005327) CoPub data access protocol, service resource, software resource, web service Text mining tool that detects co-occuring biomedical concepts in abstracts from the MedLine literature database. It allows batch input of multiple human, mouse or rat genes and produces lists of keywords from several biomedical thesauri that are significantly correlated with the set of input genes. These lists link to Medline abstracts in which the co-occurring input genes and correlated keywords are highlighted. Furthermore, CoPub can graphically visualize differentially expressed genes and over-represented keywords in a network, providing detailed insight in the relationships between genes and keywords, and revealing the most influential genes as highly connected hubs. microarray, gene, literature, enrich, annotate, network, database, differential expression, bio.tools uses: MEDLINE
uses: Gene Ontology
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Netherlands Bioinformatics Centre
Netherlands Bioinformatics Centre PMID:18442992 Free, Public, Acknowledgement requested OMICS_01178, biotools:copub https://bio.tools/copub http://services.nbic.nl/cgi-bin/copub/CoPub.pl SCR_005327 2026-09-19 12:50:51 5
FaBox
 
Resource Report
Resource Website
100+ mentions
FaBox (RRID:SCR_005350) FaBox software resource Tools for splitting, joining and otherwise manipulating FASTA format sequence files. The first tools in the toolbox is for manipulating fasta headers, cropping alignments and doing some sequence comparison allowing users to combine the description of data (often in excel spreadsheets) with the actual data (often DNA sequences). Also, producing correct input files for a range of programs seems to be problematic for the average user. Hence, some converters in some of the services have been included as well as some stand-alone converters. The converters are not necessarily meant to provide the final input file, but you''ll get a valid input file for Arlequin, MrBayes etc. - that you may further edit so it suit your needs. This means that you may need to combine several of the tools to finish your handling - but it keeps it relatively simple to use. Please note that FaBox is written in PHP and ONLY RUNS ON A WEBSERVER. fasta, dna, protein sequence, dna sequence, protein, sequence, php is listed by: OMICtools
has parent organization: Aarhus University; Aarhus; Denmark
Acknowledgement requested OMICS_01165 SCR_005350 FaBox - an online fasta sequence toolbox 2026-09-19 12:50:52 120

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