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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
QuickGO
 
Resource Report
Resource Website
500+ mentions
QuickGO (RRID:SCR_004608) QuickGO web service, software resource, controlled vocabulary, data access protocol, ontology, database, data or information resource A web-based browser for Gene Ontology terms and annotations, which is provided by the UniProtKB-GOA group at the EBI. It is able to offer a range of facilities including bulk downloads of GO annotation data which can be extensively filtered by a range of different parameters and GO slim set generation. The software for QuickGO is freely available under the Apache 2 license. QuickGO can supply GO term information and GO annotation data via REST web services. gene, ontology, annotation, browser, visualization, search engine, slimmer-type tool, ontology or annotation browser, ontology or annotation search engine, ontology or annotation visualization, database or data warehouse, windows, mac os x, linux, unix, gold standard, bio.tools is listed by: OMICtools
is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: STRAP
has parent organization: European Bioinformatics Institute
BBSRC BB/E023541/1 PMID:19744993
PMID:20157483
Apache License, v2, Free for academic use biotools:quickgo, nlx_60318, OMICS_02276 https://bio.tools/quickgo SCR_004608 Quick GO 2026-08-04 09:41:10 523
Small Molecule Pathway Database
 
Resource Report
Resource Website
50+ mentions
Small Molecule Pathway Database (RRID:SCR_004844) SMPDB data analysis service, analysis service resource, production service resource, service resource, image, database, data or information resource An interactive, visual database containing more than 350 small molecule pathways found in humans. More than 2/3 of these pathways (>280) are not found in any other pathway database. SMPDB is designed specifically to support pathway elucidation and pathway discovery in metabolomics, transcriptomics, proteomics and systems biology. It is able to do so, in part, by providing exquisitely detailed, fully searchable, hyperlinked diagrams of human metabolic pathways, metabolic disease pathways, metabolite signaling pathways and drug-action pathways. All SMPDB pathways include information on the relevant organs, subcellular compartments, protein cofactors, protein locations, metabolite locations, chemical structures and protein quaternary structures. Each small molecule is hyperlinked to detailed descriptions contained in the HMDB or DrugBank and each protein or enzyme complex is hyperlinked to UniProt. All SMPDB pathways are accompanied with detailed descriptions and references, providing an overview of the pathway, condition or processes depicted in each diagram. The database is easily browsed and supports full text, sequence and chemical structure searching. Users may query SMPDB with lists of metabolite names, drug names, genes / protein names, SwissProt IDs, GenBank IDs, Affymetrix IDs or Agilent microarray IDs. These queries will produce lists of matching pathways and highlight the matching molecules on each of the pathway diagrams. Gene, metabolite and protein concentration data can also be visualized through SMPDB''s mapping interface. All of SMPDB''s images, image maps, descriptions and tables are downloadable. metabolomics, transcriptomics, proteomics, systems biology, small molecule, pathway, human, metabolic pathway, metabolic disease pathway, metabolite signaling pathway, drug-action pathway, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is related to: ConsensusPathDB
has parent organization: University of Alberta; Alberta; Canada
Genome Alberta ;
Genome Canada
PMID:19948758 nlx_143926, biotools:smpdb, r3d100012753 https://bio.tools/smpdb, https://doi.org/10.17616/R3TB93 SCR_004844 SMPDB (The Small Molecule Pathway Database), Small Molecule Pathway Database (SMPDB) 2026-08-04 09:41:13 95
NCBI Probe
 
Resource Report
Resource Website
10+ mentions
NCBI Probe (RRID:SCR_004816) NCBI Probe storage service resource, data repository, service resource, database, data or information resource Public registry of nucleic acid reagents designed for use in a wide variety of biomedical research applications including genotyping, gene expression studies, SNP discovery, genome mapping, and gene silencing. Probe records contain information on reagent distributors, probe effectiveness, and computed sequence similarities. The database is constantly updated, with over 11,000,000 probes available. Users may deposit their data into NCBI Probe Database. reagent, probe, registry, nucleic acid, gene expression, gene mapping, gene silencing, dna data bank, nucleic acid probe, gold standard, bio.tools is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: UniSTS
has parent organization: NCBI
Public, The community can contribute to this resource nlx_80513, r3d100010780, biotools:ncbi_dbprobe http://www.ncbi.nlm.nih.gov/sites/entrez?db=probe, https://bio.tools/ncbi_dbprobe, https://doi.org/10.17616/R3D041 SCR_004816 NCBI Probe Database, Entrez Probe Database, ProbeDB, Probe Database, dbProbe 2026-08-04 09:41:13 17
European Genome phenome Archive
 
Resource Report
Resource Website
500+ mentions
European Genome phenome Archive (RRID:SCR_004944) EGA data set, web service, storage service resource, software resource, data access protocol, data repository, service resource, data or information resource Web service for permanent archiving and sharing of all types of personally identifiable genetic and phenotypic data resulting from biomedical research projects. The repository allows you to explore datasets from numerous genotype experiments, supplied by a range of data providers. The EGA''s role is to provide secure access to the data that otherwise could not be distributed to the research community. The EGA contains exclusive data collected from individuals whose consent agreements authorize data release only for specific research use or to bona fide researchers. Strict protocols govern how information is managed, stored and distributed by the EGA project. As an example, only members of the EGA team are allowed to process data in a secure computing facility. Once processed, all data are encrypted for dissemination and the encryption keys are delivered offline. The EGA also supports data access only for the consortium members prior to publication. phenomenon, trait, sequence, genotype, experiment, case-control, population, family study, snp, cnv, phenotype, genomic, gold standard, bio.tools is used by: Blueprint Epigenome
is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
lists: METABRIC
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: European Bioinformatics Institute
PMID:34791407 Restricted BioTools:ega, biotools:ega, r3d100011242, OMICS_01028, nlx_91316 https://ega-archive.org/, https://bio.tools/ega, https://bio.tools/ega, https://doi.org/10.17616/R3W619 SCR_004944 , The European Genome-phenome Archive, The European Genome-phenome Archive (EGA), EGA 2026-08-04 09:41:15 605
Percolator: Semi-supervised learning for peptide identification from shotgun proteomics datasets
 
Resource Report
Resource Website
1000+ mentions
Percolator: Semi-supervised learning for peptide identification from shotgun proteomics datasets (RRID:SCR_005040) software resource, database, data or information resource Percolator post-processes the results of a shotgun proteomics database search program, re-ranking peptide-spectrum matches so that the top of the list is enriched for correct matches. Shotgun proteomics uses liquid chromatography-tandem mass spectrometry to identify proteins in complex biological samples. We describe an algorithm, called Percolator, for improving the rate of peptide identifications from a collection of tandem mass spectra. Percolator uses semi-supervised machine learning to discriminate between correct and decoy spectrum identifications, correctly assigning peptides to 17% more spectra from a tryptic dataset and up to 77% more spectra from non-tryptic digests, relative to a fully supervised approach. The yeast-01 data is available in tab delimetered format. The SEQUEST parameter file and target database for the yeast and worm data are also available. worm, yeast, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Washington; Seattle; USA
PMID:17952086 biotools:percolator, nlx_98814 https://bio.tools/percolator SCR_005040 Percolator 2026-08-04 09:41:16 2482
SINA
 
Resource Report
Resource Website
100+ mentions
SINA (RRID:SCR_005067) SINA data analysis service, analysis service resource, software resource, production service resource, service resource Service to align and optionally taxonomically classify your rRNA gene sequences. The results can be combined with any other sequences aligned by SINA or taken from the SILVA databases by concatenation of FASTA files or using the ARB MERGE tool. Note: Submission is currently limited to at most 1000 sequences of at most 6000 bases each. If your requirements exceed this limitation, get Opens internal link in current windowSINA for local installation. alignment, taxonomic classification, rrna, gene sequence, fasta, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: SILVA
is related to: ARB project
has parent organization: Max Planck Institute for Marine Microbiology; Bremen; Germany
PMID:22556368 Free, Available for download, Freely available OMICS_01438, biotools:sina https://bio.tools/sina, https://sources.debian.org/src/sina/, https://github.com/epruesse/SINA SCR_005067 SINA Alignment Service, SILVA Incremental Aligner 2026-08-04 09:41:17 369
Subread
 
Resource Report
Resource Website
1000+ mentions
Subread (RRID:SCR_009803) data processing software, software application, software resource Software package for high-performance read alignment, quantification and mutation discovery.General purpose read aligner which can be used to map both genomic DNA-seq reads and RNA-seq reads. Subread aligner as fast, accurate and scalable read mapping by seed-and-vote.These programs were also implemented in Bioconductor R package Rsubread. read alignment, DNA-seq reads mapping, RNA-seq reads mapping, mutation discovery, , bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Rsubread
has parent organization: University of Melbourne; Victoria; Australia
Australian National Health and Medical Research Council ;
Victorian State Government Operational Infrastructure Support ;
Australian Government
PMID:23558742 Free, Freely available OMICS_01255, biotools:subread https://bio.tools/subread, https://sources.debian.org/src/subread/ SCR_009803 2026-08-04 09:42:28 1854
Assisted Model Building with Energy Refinement (AMBER)
 
Resource Report
Resource Website
1000+ mentions
Assisted Model Building with Energy Refinement (AMBER) (RRID:SCR_014230) AMBER simulation software, software application, standalone software, software resource Software package of molecular simulation programs. It is distributed into AmberTools15 and Amber14. AmberTools15 is a software package which can carry out complete molecular dynamics simulations with either explicit water or generalized Born solvent models. It is distributed in source code format and must be compiled in order to be used. Amber14 builds on AmberTools15 by adding the pmemd program, which provides better performance on multiple CPUs and dramatic speed improvements on GPUs compared to sander (molecular dynamics). GPU info, manuals, and tutorials are available on the website. molecular simulation, simulation software, software package, molecular dynamics, pmemed, sander, bio.tools is listed by: bio.tools
is listed by: Debian
Acknowledgement requested biotools:amber https://bio.tools/amber SCR_014230 Assisted Model Building with Energy Refinement 2026-08-04 09:43:23 4032
GSA-SNP
 
Resource Report
Resource Website
10+ mentions
GSA-SNP (RRID:SCR_013109) GSA-SNP data processing software, software application, software resource A tool for the gene-set (or pathway) analysis of a genome-wide association study result. It accepts a genome-wide list of SNPs and their association P-values. It summarizes the SNP P-values into nearby genes. The gene-by-gene summary results are then further summarized by gene-sets such as Gene Ontology, KEGG pathways, or user-created gene-sets. Various standardization and statistical tests can be performed and the resulting gene-sets that pass a significance level after multiple-testing correction are reported. The tool is written in Java and is available as a standalone version. clinical neuroinformatics, computational neuroscience, imaging genomics, bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: bio.tools
has parent organization: Soongsil University; Seoul; South Korea
PMID:20501604 GNU General Public License v2 nlx_155765, biotools:gsa-snp https://bio.tools/gsa-snp SCR_013109 2026-08-04 09:43:08 18
Trim Galore
 
Resource Report
Resource Website
5000+ mentions
Rating or validation data
Trim Galore (RRID:SCR_011847) Trim Galore! data processing software, software application, software resource Software tool to automate quality and adapter trimming as well as quality control, with some added functionality to remove biased methylation positions for RRBS sequence files for directional, non-directional or paired-end sequencing. Wrapper around Cutadapt and FastQC to consistently apply adapter and quality trimming to FastQ files, with extra functionality for Reduced Representation Bisulfite Sequencing data. Automate, quality, adapter, trimming, remove, biased, methylation, position, RRBS, reduced, representation, bisulfite, data, sequence, wrapper, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Babraham Institute
works with: cutadapt
Free, Available for download, Freely available biotools:trim_galore, OMICS_01096, SCR_016946 https://github.com/FelixKrueger/TrimGalore, https://bio.tools/trim_galore, https://sources.debian.org/src/trim-galore/ SCR_011847 TrimGalore 2026-08-04 09:42:52 6255
PALEOMIX
 
Resource Report
Resource Website
50+ mentions
PALEOMIX (RRID:SCR_015057) data processing software, software application, software resource, software toolkit THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software toolkit for the processing of ancient and modern HTS data. PALEOMIX also aids in metagenomic analysis of the extracts from the HTS processing. hts data, high-throughput sequencing, ancient dna, adna, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:24722405
DOI:10.1038/nprot.2014.063
THIS RESOURCE IS NO LONGER IN SERVICE biotools:paleomix, OMICS_03749 https://bio.tools/paleomix, https://sources.debian.org/src/paleomix/ SCR_015057 2026-08-04 09:43:34 65
NeLS
 
Resource Report
Resource Website
1+ mentions
NeLS (RRID:SCR_016301) NeLS portal, organization portal, data or information resource Web portal for the administration of Norwegian e-Infrastructure for Life Sciences. Enables Norwegian life scientists and their international collaborators to store, share, archive, and analyse their genomics scale data. NeLS is one of the packages of the ELIXIR.NO project. genomic, data, analyze, store, share, archive, electronic, infrastructure, administration, Norway, bio.tools is listed by: bio.tools
is listed by: Debian
Research Council of Norway Free, Freely available biotools:nels https://bio.tools/nels, https://github.com/elixir-no-nels/nels-core, https://bio.tools/nels SCR_016301 Norwegian e-Infrastructure for Life Sciences 2026-08-04 09:43:52 3
ProCon - PROteomics CONversion
 
Resource Report
Resource Website
1+ mentions
ProCon - PROteomics CONversion (RRID:SCR_016363) ProCon data processing software, software application, software resource Java based conversion tool for conversion of data from Proteomics files or a LIMS (Laboratory Information Management System) database into standard formats. Used to support wet-lab scientists in creating proteomics data files ready for upload into the public repositories. data, proteomics, conversion, file, laboratory, information, management, system, database, standard, format, , bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Ruhr University Bochum; North Rhine-Westphalia; Germany
European Union Projects ProDac ;
European Union Projects ProteomeXchange ;
the German Federal Ministry of Education and Research BMBF
PMID:26182917 Free, Available for download, Freely available biotools:procon https://bio.tools/procon SCR_016363 PROteomics CONversion 2026-08-04 09:43:53 1
STRUCTURE
 
Resource Report
Resource Website
1000+ mentions
STRUCTURE (RRID:SCR_017637) software resource, software toolkit Software package for using multi locus genotype data to investigate population structure. Used for inferring presence of distinct populations, assigning individuals to populations, studying hybrid zones, identifying migrants and admixed individuals, and estimating population allele frequencies in situations where many individuals are migrants or admixed. Can be applied to most of commonly used genetic markers, including SNPS, microsatellites, RFLPs and Amplified Fragment Length Polymorphisms. Multi locus genotype data, investigate population structure, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: STRAT
has parent organization: Stanford University; Stanford; California
works with: Structure Harvester
PMID:21564903
PMID:18784791
PMID:12930761
PMID:10835412
Free, Available for download, Freely available SCR_021634, nlx_154662, biotools:structure, SCR_002151 https://bio.tools/structure, http://pritch.bsd.uchicago.edu/structure.html, SCR_017637 structure, Structure 2026-08-04 09:44:11 4017
Racon
 
Resource Report
Resource Website
100+ mentions
Racon (RRID:SCR_017642) data processing software, software application, software resource Software tool as de novo genome assembly from long uncorrected reads. Used to correct raw contigs generated by rapid assembly methods which do not include consensus step. Supports data produced by Pacific Biosciences and Oxford Nanopore Technologies. Assembly, de novo, long, uncorrected, read, raw, contig, consensus, step, data, sequence, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
Croatian Science Foundation ;
Croatian Academy of Sciences and Arts ;
A*STAR ;
Singapore
DOI:10.1101/068122 Free, Available for download, Freely available OMICS_25714, biotools:Racon, BioTools:Racon https://bio.tools/Racon, https://sources.debian.org/src/racon/ SCR_017642 2026-08-04 09:44:10 149
TransDecoder
 
Resource Report
Resource Website
1000+ mentions
TransDecoder (RRID:SCR_017647) data processing software, software application, standalone software, software resource Software tool to identify candidate coding regions within transcript sequences, such as those generated by de novo RNA-Seq transcript assembly using Trinity, or constructed based on RNA-Seq alignments to genome using Tophat and Cufflinks.Starts from FASTA or GFF file. Can scan and retain open reading frames (ORFs) for homology to known proteins by using BlastP or Pfam search and incorporate results into obtained selection. Predictions can then be visualized by using genome browser such as IGV. Identify, candidate, coding, region, transcript, sequence, de novo, RNAseq, assembly, alignment, genome, open, reading, frame, homology, protein, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:transDecoder, OMICS_10852 https://bio.tools/TransDecoder, https://sources.debian.org/src/transdecoder/, https://github.com/TransDecoder/TransDecoder/wiki SCR_017647 , Find Coding Regions Within Transcripts 2026-08-04 09:44:15 1309
docker4seq
 
Resource Report
Resource Website
1+ mentions
docker4seq (RRID:SCR_017006) data processing software, software application, software resource Software R package to execute next generation sequencing computing applications, e.g. reads mapping and counting, wrapped in docker containers. next, generation, sequencing, computing, application, read, mapping, count, docker, container, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: University of Turin;Turin;Italy
Free, Available for download, Freely available biotools:docker4seq https://kendomaniac.github.io/docker4seq/index.html, https://bio.tools/docker4seq SCR_017006 2026-08-04 09:44:04 5
GeSeq
 
Resource Report
Resource Website
100+ mentions
GeSeq (RRID:SCR_017336) data processing software, software application, software resource, service resource Software tool for rapid and accurate annotation of organelle genomes, in particular chloroplast genomes. rapid, accurate, annotation, organelle, genome, chloroplast, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Human Frontier Science Program ;
Max Planck Society ;
German Science Foundation
PMID:28486635 Free, Freely available biotools:geseq https://bio.tools/geseq SCR_017336 2026-08-04 09:44:09 375
FlowCal
 
Resource Report
Resource Website
1+ mentions
FlowCal (RRID:SCR_018140) data processing software, software application, software resource Open source software tool for automatically converting flow cytometry data from arbitrary to calibrated units. Can be run using intuitive Microsoft Excel interface, or customizable Python scripts. Software accepts Flow Cytometry Standard (FCS) files as inputs and is compatible with different calibration particles, fluorescent probes, and cell types. Automatically gates data, calculates common statistics, and produces plots. Converting flow cytometry data, arbitrary unit, calibrated unit, data gating, statistic, plot, data, bio.tools is listed by: Debian
is listed by: bio.tools
NSF EFRI 1137266;
NSF MCB 1244135;
Office of Naval Research MURI N000141310074;
Office of Naval Research YIP N000141410487;
NIAID R21 AI115014;
Welch Foundation ;
NSF Graduate Research Fellowship DGE 0940902;
NDSEG Fellowship
PMID:27110723 Free, Available for download, Freely available biotools:flowcal https://bio.tools/flowcal SCR_018140 Python Flow Cytometry Calibration Library 2026-08-04 09:44:17 5
ScaffMatch
 
Resource Report
Resource Website
1+ mentions
ScaffMatch (RRID:SCR_017025) data processing software, software application, software resource Software tool as scaffolding algorithm based on maximum weight matching able to produce high quality scaffolds from next generation sequencing data (reads and contigs). Able to handle reads with both short and long insert sizes. scaffolding, algorithm, maximum, weight, matching, next, generation, sequencing, data, read, contig, bio.tools uses: Python Programming Language
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Georgia State University; Georgia; USA
NSF IIS 0916401 PMID:25890305 Free, Available for download, Freely available biotools:scaffmatch, OMICS_08198 http://alan.cs.gsu.edu/NGS/?q=content/scaffmatch, https://bio.tools/scaffmatch SCR_017025 2026-08-04 09:44:03 1

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