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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Human Islet Research Network (HIRN) Resource Report Resource Website 100+ mentions |
Human Islet Research Network (HIRN) (RRID:SCR_014393) | HIRN | data or information resource, topical portal, portal, disease-related portal | Network helps to organize and support collaborative research related to loss of functional beta cell mass in Type 1 Diabetes (T1D). Project consists of four independent research initiatives: Consortium on Beta Cell Death and Survival (CBDS), Consortium on Human Islet Biomimetics (CHIB), Consortium on Modeling Autoimmune Interactions (CMAI), Consortium on Targeting and Regeneration (CTAR), and Human Pancreas Analysis Program (HPAP). | islet, human, consortia, functional loss, beta cell, research network, funding resource |
is used by: Hypothesis Center is listed by: NIDDK Information Network (dkNET) is related to: Pancreatlas is related to: scPancMeta App is related to: PANC-DB has organization facet: HIRN Consortium on Beta Cell Death and Survival has organization facet: HIRN Consortium on Human Islet Biomimetics has organization facet: HIRN Consortium on Modeling Autoimmune Interactions has organization facet: HIRN Consortium on Targeting and Regeneration has organization facet: HIRN Human Pancreas Analysis Program has organization facet: HIRN Bioinformatics Center has organization facet: HIRN Coordinating Center has organization facet: HIRN Human Pancreas Analysis Consortium |
Type 1 diabetes, Diabetes | NIDDK | SCR_014393 | Human Islet Research Network | 2026-08-05 10:46:07 | 222 | |||||||
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Collaborating for the Advancement of Interdisciplinary Research in Benign Urology Resource Report Resource Website 1+ mentions |
Collaborating for the Advancement of Interdisciplinary Research in Benign Urology (RRID:SCR_022876) | CAIRIBU | data or information resource, topical portal, portal, disease-related portal | Community of researchers studying benign urology diseases at U54 O’Brien Cooperative Research Centers, P20 Exploratory Centers, and K12 Career Development Programs funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), one of the institutes within the National Institutes of Health (NIH). CAIRIBU Centers and Programs are united around the overall objectives of improving our understanding of the mechanisms of urogenital diseases and developing clinical therapies for treating them by building collaborative and interactive research platforms that span the gamut from basic to translational to population research. | urogenital diseases, clinical therapies development |
lists: Cell Ranger lists: Human Tissue and Organ for Research Resource (HTORR) lists: GenitoUrinary Development Molecular Anatomy Project lists: Multi-Disciplinary Approach to the Study of Chronic Pelvic Pain lists: Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) lists: Prevention of Lower Urinary Tract Symptoms lists: Pediatric KIDney Stone Care Improvement Network lists: SBUR - Society for Basic Urologic Research lists: Society of Benign Prostate Disease lists: Society of Urodynamics, Female Pelvic Medicine and Urogenital Reconstruction (SUFU) lists: Research on Calculus Kinetics Society lists: American Urological Association lists: Endourological Society lists: NIDDK Information Network (dkNET) lists: Tissue Microarray Database lists: Stanford University School of Medicine O’Brien Urology Research Center Biospecimen/Bioimaging Core Facility lists: O'Brien Center for Benign Urologic Research at University of Wisconsin-Madision and University of Massachusetts-Boston lists: Columbia University George M. O'Brien Urology Center |
Free, Freely available | SCR_022876 | 2026-08-05 10:47:43 | 1 | |||||||||
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caHUB Resource Report Resource Website |
caHUB (RRID:SCR_009657) | caHUB | data or information resource, standard specification, narrative resource | THIS RESOURCE IS NO LONGER IN SERVICE. Documented July 5, 2018. A national center for biospecimen science and standards to advance cancer research and treatment. It was created in response to the critical and growing need for high-quality, well-documented biospecimens for cancer research. The initiative builds on resources already developed by the NCI, including the Biospecimen Research Network and the NCI Best Practices for Biospecimen Resources, both of which were developed to address challenges around standardization of the collection and dissemination of quality biospecimens. caHUB will develop the infrastructure for collaborative biospecimen research and the production of evidence-based biospecimen standard operating procedures. | biospecimen, clinical, biomaterial supply resource, tissue |
is listed by: NIDDK Information Network (dkNET) is related to: Biorepositories and Biospecimens Research Branch has parent organization: National Cancer Institute |
Cancer | NCI ; ARRA |
THIS RESOURCE IS NO LONGER IN SERVICE | nlx_156094 | SCR_009657 | The Cancer Human Biobank, cancer Human Biobank | 2026-08-05 10:45:09 | 0 | |||||
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Zebrafish Information Network (ZFIN) Resource Report Resource Website 500+ mentions |
Zebrafish Information Network (ZFIN) (RRID:SCR_002560) | ZFIN | data or information resource, database | Model organism database that serves as central repository and web-based resource for zebrafish genetic, genomic, phenotypic and developmental data. Data represented are derived from three primary sources: curation of zebrafish publications, individual research laboratories and collaborations with bioinformatics organizations. Data formats include text, images and graphical representations.Serves as primary community database resource for laboratory use of zebrafish. Developed and supports integrated zebrafish genetic, genomic, developmental and physiological information and link this information extensively to corresponding data in other model organism and human databases. | expression, gene, anatomy, development, disease, genomic, model, molecular, mutant, neuronal, organism, phenotype, physiological, synteny, zebrafish, gene expression, genome sequence, molecular neuroanatomy resource, genotype, anatomical structure, publication, genome, image collection, gold standard, bio.tools, FASEB list, RRID Community Authority |
uses: InterMOD is used by: NIF Data Federation is used by: Resource Identification Portal is used by: Morpholino Database is used by: Integrated Animals is used by: NIH Heal Project is recommended by: Resource Identification Portal is recommended by: NIDDK Information Network (dkNET) is recommended by: National Library of Medicine is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases is listed by: OMICtools is listed by: InterMOD is listed by: re3data.org is listed by: bio.tools is listed by: Debian is related to: AmiGO is related to: Phenoscape Knowledgebase is related to: MONARCH Initiative is related to: Bgee: dataBase for Gene Expression Evolution is related to: NIH Data Sharing Repositories is related to: HomoloGene is related to: Zebrafish International Resource Center is related to: Integrated Manually Extracted Annotation is related to: Zebrafish Genome Project has parent organization: University of Oregon; Oregon; USA is parent organization of: ZFIN Antibody Database is parent organization of: Zebrafish Anatomical Ontology is parent organization of: ZFIN Protocol Wiki is parent organization of: ZFIN Antibody Wiki is organization facet of: Alliance of Genome Resources |
NHGRI P41 HG002659; NHGRI R01 HG004834 |
PMID:23074187 PMID:21036866 PMID:16381936 |
Free, Available for download, Freely available | OMICS_01666, nif-0000-21427, biotools:zfin, r3d100010421, SCR_017504 | http://zfin.org/ZFIN/misc_html/tips.html#newrecord, https://wiki.zfin.org/display/general/ZFIN+Data+Submissions, https://bio.tools/zfin, https://doi.org/10.17616/R3CK5Z | SCR_002560 | Zebrafish Database, The Zebrafish Model Organism Database, Zebra Model Organism Database, ZebraFish Information Network, ZFIN | 2026-08-05 10:43:38 | 898 | ||||
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Network Data Exchange (NDEx) Resource Report Resource Website 50+ mentions |
Network Data Exchange (NDEx) (RRID:SCR_003943) | NDEx | data or information resource, database | Repository where scientists and organizations can share, store, manipulate, and publish biological network data. Users can also run their own copies of NDEx Server software in cases where stored networks must be kept in highly secure environment (such as for HIPAA compliance) or where high application load is incompatible with shared public resource. Open source software system that is part of Cytoscape family. Project of Cytoscape Consortium in conjunction with Ideker lab at UCSD School of Medicine. Public forum where biologists can exchange and publish computable network models in many types and formats. NDEx is based on REST web API which can be accessed by any application, including NDEx website and NDEx Cytoscape App. NDEx networks are assigned stable, globally unique URIs and so can be referenced by publications, by other networks, and by analytic applications. | network, pathway, network model, web service, FASEB list |
is recommended by: National Library of Medicine is recommended by: NIDDK Information Network (dkNET) is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases is listed by: DataCite is related to: Cytoscape has parent organization: University of California at San Diego; California; USA has parent organization: University of California; California; USA |
PMID:34570431 PMID:28150243 |
Free, Freely available | nlx_158334, r3d100000028 | http://ndexbio.org/, http://www.home.ndexbio.org/disclaimer-license/, http://www.ndexbio.org/#/, https://api.datacite.org/dois?prefix=10.18119, https://doi.org/10.17616/R3PP4D | SCR_003943 | ndex bio, NDEx, Network Data Exchange, UCSD NDEx, ndex biology, the Network Data Exchange | 2026-08-05 10:43:57 | 79 | |||||
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STRING Resource Report Resource Website 10000+ mentions |
STRING (RRID:SCR_005223) | STRING | data or information resource, database | Database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations and are derived from four sources: Genomic Context, High-throughput experiments, (Conserved) Coexpression, and previous knowledge. STRING quantitatively integrates interaction data from these sources for a large number of organisms, and transfers information between these organisms where applicable. The database currently covers 5''214''234 proteins from 1133 organisms. (2013) | protein association, protein functional association, protein interaction, protein-protein interaction, protein, sequence, protein sequence, interaction, gene, FASEB list |
is used by: MobiDB is used by: PAXdb is listed by: Nuclear Receptor Signaling Atlas is listed by: NIDDK Information Network (dkNET) is related to: Biomine is related to: PSICQUIC Registry is related to: ShinyGO has parent organization: European Molecular Biology Laboratory has plug in: Cytoscape StringApp |
BMBF ; European Union FP6 ; EMBO ; ProBioC ; Swiss Institute of Bioinformatics |
PMID:23203871 PMID:21045058 PMID:18940858 PMID:17098935 PMID:15608232 PMID:12519996 |
nif-0000-03503, r3d100010604 | https://doi.org/10.17616/R3VS40 | SCR_005223 | Search Tool for the Retrieval of Interacting Genes/Proteins, STRING - Known and Predicted Protein-Protein Interactions | 2026-08-05 10:44:12 | 29246 | |||||
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CARDS Database Resource Report Resource Website 1+ mentions |
CARDS Database (RRID:SCR_009011) | CARDS, CARDS Database | data or information resource, database | Database of federally funded research projects pertaining to dietary supplements. CARDS contains projects funded by the United States Department of Agriculture (USDA), the Department of Defense (DOD) and the Institutes and Centers (ICs) of the National Institutes of Health (NIH) beginning with fiscal year 1999, the first year that NIH ICs began reporting research related to dietary supplements. Projects funded by other Federal agencies will be added to CARDS as they become available. The Office of Dietary Supplements (ODS) will post notices on its website and listserv when CARDS updates are completed. Codes assigned to each research project allow the CARDS user to identify: * research related to specific dietary supplement ingredients; for example, vitamin E or St. John''''s wort * the type of study; for example, a Phase III study or an animal study * health outcomes or biological effects; for example, osteoporosis or antioxidant function * whether the research is directly related or indirectly related to dietary supplements. For example, a clinical trial comparing bone density in women given a daily calcium supplement versus a placebo would be classified as directly related to dietary supplements. A study examining the activation of steroid hormone receptors by supplemental vitamin D in cell culture would be classified as indirectly related to dietary supplements because the direct physiological or health effects of vitamin D supplementation are not being studied. A search of the CARDS database can be used to sort and tabulate information for a variety of purposes. For example, a researcher may want to know which ICs at the NIH fund research on herbal supplement ingredients. A consumer may want to know if the Federal government is supporting research on a popular dietary supplement ingredient such as vitamin C. | dietary supplement |
is related to: Human Nutrition Research Information Management is related to: NIDDK Information Network (dkNET) has parent organization: National Institutes of Health |
NIH | nlx_152703 | SCR_009011 | Computer Access to Research on Dietary Supplements Database, Computer Access to Research on Dietary Supplements | 2026-08-05 10:45:06 | 1 | |||||||
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Biologic Specimen and Data Repository Information Coordinating Center (BioLINCC) Resource Report Resource Website 100+ mentions |
Biologic Specimen and Data Repository Information Coordinating Center (BioLINCC) (RRID:SCR_013142) | BioLINCC | data or information resource, database | Repository that serves to coordinate searches across data and biospecimen collections from participants in numerous clinical trials and epidemiologic studies and to provide an electronic means for requests for additional information and the submission of requests for collections. The collections, comprising data from more than 80 trials or studies and millions of biospecimens, are available to qualified investigators under specific terms and conditions consistent with the informed consents provided by the individual study participants. Some datasets are presented with studies and supporting materials to facilitate their use in reuse and teaching. Datasets support basic research, clinical studies, observational studies, and demonstrations. Researchers wishing to apply to submit biospecimen collections to the NHLBI Biorepository for sharing with qualified investigators may also use this website to initiate that process. | cardiovascular, pulmonary, hematology, clinical, clinical trial, blood, lung, heart, biological specimen, health, disease, medicine, epidemiology, epidemiologic study, FASEB list |
is listed by: One Mind Biospecimen Bank Listing is listed by: DataCite is listed by: NIH Data Sharing Repositories is listed by: Connected Researchers is listed by: NIDDK Information Network (dkNET) is related to: NIH Data Sharing Repositories is related to: Framingham Heart Study has parent organization: National Heart Lung and Blood Institute |
NHLBI | Public, The community can contribute to this resource | r3d100010834, nlx_151758 | https://biolincc.nhlbi.nih.gov/, https://biolincc.nhlbi.nih.gov/ | SCR_013142 | NHLBI Biorepository | 2026-08-05 10:45:57 | 250 | |||||
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Kidney Development Database Resource Report Resource Website 1+ mentions |
Kidney Development Database (RRID:SCR_013374) | data or information resource, database | The Kidney Development Database was created to collect in one place the data from a large number of developmental studies that have a bearing on the study of kidney development. With its oldest parts dating back to 1993/4, it is, as far as we know, the earliest computer database in the field of vertebrate organogenesis. Data are displayed in tables, arranged according to a standard scheme of kidney development explained in the key. Many of the entries are derived from low-power in situs or published text-only descriptions, and should therefore be interpreted with mild caution. | kidney development, computer database, vertebrate, kidney |
uses: GUDMAP Ontology is related to: NIDDK Information Network (dkNET) has parent organization: University of Edinburgh; Scotland; United Kingdom |
nif-0000-03068 | SCR_013374 | KDD | 2026-08-05 10:45:55 | 4 | |||||||||
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Nuclear Receptor Cistrome Resource Report Resource Website 1+ mentions |
Nuclear Receptor Cistrome (RRID:SCR_014515) | data or information resource, database | A web-interface that enables users to access and download the processed ChIP chip/seq data of nuclear receptors, co-regulators and histone modifications. The web resources also includes processed differential expression data under ligand induction in conditions matched to ChIP_chip/seq data whenever possible. All the ChIP chip/seq peak regions are annotated with enriched HRE and co-regulator motifs. A list of predicted hormone response genes from integration of nuclear receptor ChIP chip/seq data and differential expression data is also readily available to the users. | database, nuclear receptor, web interface, chip, histone, peak |
is listed by: Nuclear Receptor Signaling Atlas is listed by: NIDDK Information Network (dkNET) |
Public, Available to the research community | SCR_014515 | NR Cistrome | 2026-08-05 10:46:07 | 1 | |||||||||
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GATACA GUDMAP Gene Explorer Resource Report Resource Website |
GATACA GUDMAP Gene Explorer (RRID:SCR_014518) | data or information resource, database | A database which can be used to search for genes critical for a variety of Genito-Urinary system functions and diseases. | genito-urinary system, genes, genetic diseases |
uses: GUDMAP Ontology is listed by: NIDDK Information Network (dkNET) has parent organization: GenitoUrinary Development Molecular Anatomy Project |
NIDDK | Freely available | SCR_014518 | 2026-08-05 10:46:10 | 0 | |||||||||
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Trans-Omics for Precision Medicine (TOPMed) Program Resource Report Resource Website 10+ mentions |
Trans-Omics for Precision Medicine (TOPMed) Program (RRID:SCR_015677) | TOPMED | biomaterial supply resource, data or information resource, material resource, database, tissue bank | Funding program for Precision Medicine genome sequencing from the National Institutes of Health, NHBLI. |
is listed by: NIDDK Information Network (dkNET) is related to: Broad Institute Genomics Platform is parent organization of: Phenotypes and eXposures Toolkit |
SCR_015677 | 2026-08-05 10:46:27 | 12 | |||||||||||
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University of North Carolina Center for Gastrointestinal Biology and Disease Microbiome Core Resource Report Resource Website |
University of North Carolina Center for Gastrointestinal Biology and Disease Microbiome Core (RRID:SCR_012644) | UNC School of Medicine Microbiome Core Facility | access service resource, service resource, core facility | Core facility that provides the research community with the facilities and the expertise to characterize complex microbial communities from different environments.Services offered by the Core include metagenomics methods to determine the composition and function of microbial communities using amplicon, Whole Genome Shotgun (WGS) and RNA sequencing, and traditional and high-throughput quantitative (q)PCR. | metagenomics, microbial community, rna sequencing |
is listed by: NIDDK Information Network (dkNET) is listed by: ABRF CoreMarketplace has parent organization: University of North Carolina at Chapel Hill School of Medicine; North Carolina; USA has parent organization: University of North Carolina Center for Gastrointestinal Biology and Disease is organization facet of: University of North Carolina Center for Gastrointestinal Biology and Disease |
digestive disease | NIDDK P30 DK034987 | Available to the research community | ABRF_5660, SciEx_604 | https://https://coremarketplace.org/?FacilityID=5660&citation=1 | SCR_012644 | , University of North Carolina at Chapel Hill School of Medicine Microbiome Core Facility, UNC Microbiome Core | 2026-08-05 10:45:50 | 0 | ||||
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Einstein-Mount Sinai Diabetes Research Center Human Islet and Adenovirus Core Facility Resource Report Resource Website |
Einstein-Mount Sinai Diabetes Research Center Human Islet and Adenovirus Core Facility (RRID:SCR_015066) | access service resource, service resource, core facility | Core which provides methodologies, technology and infrastructure to support investigators in the use of human islets for research studies for the Einstein-Mount Sinai Diabetes Research Center. It isolates and prepares human and rodent islets/beta cells and cell lines for investigator-initiated research and generates specific viral vectors (adenovirus and lentivirus) for gene delivery of cDNAs and shRNAs of interest to beta cells and other islet cell types. | islets, human islets, beta cells, adenovirus |
is listed by: NIDDK Information Network (dkNET) is listed by: ABRF CoreMarketplace has parent organization: Einstein-Mount Sinai Diabetes Research Center is organization facet of: Einstein-Mount Sinai Diabetes Research Center |
New York Obesity Research Center ; Center for the Study of Diabetic Complications ; Montefiore Clinical Diabetes Center ; NIDDK P30DK020541 |
Open | ABRF_2863 | https://coremarketplace.org/?FacilityID=2863&citation=1 | http://www.einstein.yu.edu/centers/diabetes-research/human-Islet-and-adenovirus-core/ | SCR_015066 | Einstein-Mount Sinai Diabetes Research Center Human Islet and Adenovirus Core | 2026-08-05 10:46:15 | 0 | |||||
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Einstein-Mount Sinai Diabetes Research Center Biomarker Analytic Research Core Facility Resource Report Resource Website 10+ mentions |
Einstein-Mount Sinai Diabetes Research Center Biomarker Analytic Research Core Facility (RRID:SCR_015067) | BARC | access service resource, service resource, core facility | Core provides information and tools for Einstein and Montefiore investigators from initial study planning stage through analysis and data output. Facility services include: mass spectrometry analysis, including stable isotopes, as well as research-grade determination of lipids, and metabolic markers for human subjects and animal model projects; High-throughput robotics for semi-automated high-quality sample preparation and analysis by immunoassay and liquid chromatography–mass spectrometry (LC/MS); Support for novel developmental projects featuring applications of LC/MS and two-site bead-based assays; Research quality analysis of metabolites for human and animal samples using Olympus AU400 autoanalyzer; Advanced training in analytical chemistry. | analytical research tools, biomarker core, mass spectrometry analysis, stable isotopes, lipids, metabolic markers, analytical chemistry, |
is listed by: NIDDK Information Network (dkNET) is listed by: ABRF CoreMarketplace has parent organization: Einstein-Mount Sinai Diabetes Research Center is organization facet of: Einstein-Mount Sinai Diabetes Research Center |
Diabetes | New York Obesity Research Center ; Center for the Study of Diabetic Complications ; Montefiore Clinical Diabetes Center ; NIDDK P30DK020541 |
Restricted | ABRF_2862 | https://coremarketplace.org/?FacilityID=2862&citation=1 | http://www.einstein.yu.edu/centers/diabetes-research/wrap.aspx?id=45634 | SCR_015067 | Einstein-Mount Sinai Diabetes Research Center Biomarker and Analytical Research Core, Einstein-Mount Sinai Diabetes Research Center Biomarker Analytic Research Core | 2026-08-05 10:46:15 | 29 | |||
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Columbia Diabetes Research Center Translational Biomarker Analytical Core Facility Resource Report Resource Website |
Columbia Diabetes Research Center Translational Biomarker Analytical Core Facility (RRID:SCR_015077) | TBAC | access service resource, service resource, core facility | Core makes available to Diabetes Research Center investigators variety of high quality radio-immunoassay, ELISA, and other analytical methods, and facilitates access of DRC investigators to measurement of small molecules by targeted and untargeted metabolomics/lipidomics with the Irving Institute Biomarkers Core. TBAC also provides consultations and services for in vivo methods to measure insulin secretion and sensitivity. | radioimmunoassay, ELISA, translational biomarker, small molecules, measure insulin secretion and sensitivity, |
is listed by: NIDDK Information Network (dkNET) is listed by: ABRF CoreMarketplace has parent organization: Columbia University; New York; USA is organization facet of: Columbia Diabetes Research Center |
Diabetes | NIDDK P30DK063608 | Open | ABRF_2859 | https://coremarketplace.org/?FacilityID=2859&citation=1 | https://www.derc.cumc.columbia.edu/core-facilities-and-services/translational-biomarker-analytical-core | SCR_015077 | , Columbia Diabetes Research Center Translational Biomarker Analytical Core, Translational Biomarker Analytical Core (TBAC) | 2026-08-05 10:46:16 | 0 | |||
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Einstein-Mount Sinai Diabetes Research Center Stable Isotope and Metabolomics Core Facility Resource Report Resource Website |
Einstein-Mount Sinai Diabetes Research Center Stable Isotope and Metabolomics Core Facility (RRID:SCR_015071) | access service resource, service resource, core facility | Core which uses stable isotope flux and metabolite profiling to help formulate and test hypotheses about the metabolic consequences of various changes in gene expression and protein function, in order to guide further integrative systems biology analyses of the underlying mechanisms in diabetes, insulin resistance, obesity, and diabetic complications. | stable isotope, insulin resistance, bile acids |
is listed by: NIDDK Information Network (dkNET) has parent organization: Einstein-Mount Sinai Diabetes Research Center is organization facet of: Einstein-Mount Sinai Diabetes Research Center |
Diabetes | New York Obesity Research Center ; Center for the Study of Diabetic Complications ; Montefiore Clinical Diabetes Center ; NIDDK P30DK020541 |
Open | SCR_015071 | Einstein-Mount Sinai Diabetes Research Center Stable Isotope and Metabolomics Core | 2026-08-05 10:46:16 | 0 | |||||||
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Einstein-Mount Sinai Diabetes Research Center Animal Physiology Core Facility Resource Report Resource Website |
Einstein-Mount Sinai Diabetes Research Center Animal Physiology Core Facility (RRID:SCR_015076) | access service resource, service resource, core facility | Core which assists with the in vivo assessment of glucose and fatty acid metabolism, insulin sensitivity and energy homeostasis in mice and rats. It provides tools to understand the behavior and physiology mediating the relationships among diabetes, nutrient sensing, obesity and diabetic cardiovascular complications in rodents. | rodent obesity, animal physiology, animal diabetes research, rodent research, obesity research |
is listed by: NIDDK Information Network (dkNET) has parent organization: Einstein-Mount Sinai Diabetes Research Center is organization facet of: Einstein-Mount Sinai Diabetes Research Center |
Diabetes | New York Obesity Research Center ; Center for the Study of Diabetic Complications ; Montefiore Clinical Diabetes Center ; NIDDK P30DK020541 |
Open | http://www.einstein.yu.edu/centers/diabetes-research/diabetes.aspx?id=1286&ekmensel=15074e5e_4046_4048_28715_1 | SCR_015076 | Einstein-Mount Sinai Diabetes Research Center Animal Physiology Core | 2026-08-05 10:46:15 | 0 | ||||||
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Boston Area Diabetes Endocrinology Research Center Transgenic Resource Report Resource Website |
Boston Area Diabetes Endocrinology Research Center Transgenic (RRID:SCR_015074) | access service resource, service resource, core facility | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 23,2024.Transgenic core which generates transgenic and gene knockout mouse models relevant to obesity, diabetes and nutrition research. It also provides consultation on all aspects of making transgenic and gene knockout mice. | transgenic mice, gene knockout mice, DNA transgenic constructs |
is listed by: NIDDK Information Network (dkNET) is organization facet of: Boston Area Diabetes Endocrinology Research Center |
Diabetes | NIDDK P30DK057521 | THIS RESOURCE IS NO LONGER IN SERVICE | SCR_015074 | 2026-08-05 10:46:16 | 0 | ||||||||
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Renin Angiotensin System Study Resource Report Resource Website 1+ mentions |
Renin Angiotensin System Study (RRID:SCR_013385) | RASS/B-RASS, RASS | clinical trial, resource | Randomized, multicenter, double-blind study to determine if renin angiotensin medications, either losartan (angiotensin II blocker) or enalapril (converting enzyme inhibitor), can prevent or delay the onset of diabetic kidney disease in patients with type 1 diabetic patients who do not have hypertension, diabetic nephropathy, or predictive levels of microalbuminuria. Two hundred eight five patients ages 16-61 with 2-20 yrs of Type 1 Diabetes Mellitus and no renal functional abnormalities were randomized into a parallel, double-blind, placebo-controlled study involving 3 groups (95 patients/group). Each group received an angiotensin-converting enzyme inhibitor (ACEI) (enalapril), or an angiotensin II receptor blocker (Losartan), or placebo. All patients had their usual Diabetes Mellitus (DM) management. Baseline studies included measures of glomerular filtration rate (GFR), urinary albumin excretion rate (UAE), blood pressure (BP), and a percutaneous renal biopsy. Patients were followed by quarterly measures of BP, HbA1C, UAE, and drug compliance. There were annual measures of GFR and a repeat renal biopsy after 5 yrs in the study. The main endpoint is kidney structural changes over time, especially mesangial fractional volume (v(Mes/glom)). Secondary endpoints will be other DN structural measures and measures of kidney function (UAE, GFR). These studies will determine whether rennin angiotensin system blockage in the early stages of DN can prevent the early kidney structural changes in this important disorder. Ancillary studies will evaluate the effects of treatment group on the development and progression of diabetic retinopathy and will develop predictors of study participants'''' compliance. Baseline, 2.5 and 5 year retinal fundus photographs in the RASS patients were obtained. | enalapril, drug, losartan, angiotensin, medication, kidney, intervention, clinical, adolescent, adult human, renal biopsy, renin-angiotensin system, diabetic nephropathy, kidney, placebo, glomerular filtration rate, urinary albumin excretion rate, blood pressure |
is related to: NIDDK Information Network (dkNET) has parent organization: ClinicalTrials.gov has parent organization: University of Minnesota Twin Cities; Minnesota; USA |
Type 1 diabetes, Diabetic kidney disease, Retinopathy, Nephropathy, Diabetes | NIDDK | PMID:19571282 | nlx_152849 | SCR_013385 | Renin Angiotensin System Blockage-DN (RASS), Renin Angiotensin System Study (RASS/B-RASS) | 2026-08-05 10:46:00 | 1 |
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