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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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CGHbase Resource Report Resource Website 1+ mentions |
CGHbase (RRID:SCR_001279) | CGHbase | data processing software, data analysis software, software resource, software application | Software package that contains functions and classes that are needed by arrayCGH packages. | copy number variation, infrastructure, microarray |
is listed by: OMICtools has parent organization: Bioconductor |
Free, Available for download, Freely available | OMICS_02057 | SCR_001279 | CGHbase: Base functions and classes for arrayCGH data analysis | 2026-08-12 10:48:22 | 1 | |||||||
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Online Neuroscience Lectures - Maintained by the Kilgard Lab Resource Report Resource Website |
Online Neuroscience Lectures - Maintained by the Kilgard Lab (RRID:SCR_001397) | video resource, portal, data or information resource, slide, topical portal | List of lectures, slides and videos concerning neuroscience and neurophysiology. | neuroscience, neurophysiology, lecture, slide, video | Free, Freely Available | nif-0000-08126 | SCR_001397 | Online Neuroscience Lectures | 2026-08-12 10:48:23 | 0 | |||||||||
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National ESCA and Surface Analysis Center for Biomedical Problems Resource Report Resource Website 1+ mentions |
National ESCA and Surface Analysis Center for Biomedical Problems (RRID:SCR_001430) | NESAC/BIO | biomaterial analysis service, service resource, production service resource, material analysis service, training resource, analysis service resource, biomedical technology research center, access service resource | Biomedical technology research center that provides state-of-the-art surface analysis expertise, instrumentation, experimental protocols, and data analysis methods to address surface-related biomedical problems. NESAC/BIO develops and applies surface science methodologies that produce a full understanding of the surface composition, structure, spatial distribution, and orientation of biomaterials and adsorbed biomolecules. The NESAC/BIO program identifies areas where surface science must evolve to keep pace with the growth in biochemical knowledge and biomaterial fabrication technology, and develops instrumentation, experimental protocols, and data analysis methods to achieve this evolution. NESAC/BIO provides state-of-the-art surface analysis tools to researchers in the biomedical community. You can gain access to the NESAC/BIO facilities in one of the following ways: * Collaborative: Propose a project to collaborate on with NESAC/BIO. The project should be rewarding for both groups, and the results should reflect the utility of surface analysis for biomedical research * Service: Ask NESAC/BIO to analyze your biomaterial specimens. The spectra obtained from the analyses will be interpreted for you. * Training: Visit the University of Washington to receive training in surface analysis and personally run experiments for your individual research projects. These experiments should have a high probability for yielding useful information and should not involve the development of new ESCA techniques or methodologies. | surface, composition, structure, spatial distribution, orientation, biomaterial, biomolecule, surface science, biochemical, biomaterial fabrication, surface analysis | has parent organization: University of Washington; Seattle; USA | NIBIB 5P41RR001296-11 | Free, Freely Available | nlx_152654 | SCR_001430 | NESAC/BIO - National ESCA and Surface Analysis Center for Biomedical Problems | 2026-08-12 10:48:23 | 1 | ||||||
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MRI Studio Resource Report Resource Website 100+ mentions |
MRI Studio (RRID:SCR_001398) | data visualization software, image analysis software, image processing software, software application, data processing software, software resource | An image processing program running under Windows suitable for such tasks as tensor calculation, color mapping, fiber tracking, and 3D visualization. Most of operations can be done with only a few clicks. This tool evolved from DTI Studio. Tools in the program can be grouped in the following way: * Image Viewer * Diffusion Tensor Calculations * Fiber Tracking and Editing * 3D Visualization * Image File Management * Region of Interesting (ROI) Drawing and Statistics * Image Registration | tensor calculation, color mapping, fiber tracking, 3d visualization, dti, image registration, mri, diffusion mr fiber tracking, microsoft, c++, analyze |
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) is related to: Diffusion Tensor Imaging ToolKit has parent organization: Johns Hopkins University; Maryland; USA works with: UManitoba - JHU Functionally Defined Human White Matter Atlas |
NCRR ; Biomedical Informatics Research Network ; NIBIB |
Free, Freely Available | nif-0000-00291 | http://www.nitrc.org/projects/mri_studio | SCR_001398 | dtiStudio, DTI Studio | 2026-08-12 10:48:23 | 180 | ||||||
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PNEUMA Resource Report Resource Website 1+ mentions |
PNEUMA (RRID:SCR_001391) | PNEUMA | simulation software, software application, software toolkit, software resource | A set of modules that are used to simulate the autoregulation of the cardiovascular and respiratory systems under conditions of changing sleep-wake state and a variety of physiological and pharmacological interventions. It models the dynamic interactions that take place among the various component mechanisms, including those involved in the chemical control of breathing, heart rate, and blood pressure, as well as the effects of changes in the sleep-wake state and arousal from sleep. PNEUMA includes the autonomic control of the cardiovascular system, chemoreflex and state-related control of breath-to-breath ventilation, state-related and chemoreflex control of upper airway potency, as well as respiratory and circulatory mechanics. The model is capable of simulating the cardiorespiratory responses to sleep onset, arousal, continuous positive airway pressure, the administration of inhaled carbon dioxide and oxygen, Valsalva and Mueller maneuvers, and Cheyne-Stokes respiration during sleep. In PNEUMA 3.0, we have extended the existing integrative model of respiratory, cardiovascular, and sleepwake state control, to incorporate a sub-model of glucoseinsulinfatty acid regulation. The extended model is capable of simulating the metabolic control of glucoseinsulin dynamics and its interactions with the autonomic nervous system. The interactions between autonomic and metabolic control include the circadian regulation of epinephrine secretion, epinephrine regulation on dynamic fluctuations in glucose and free fatty acids in plasma, metabolic coupling among tissues and organs mediated by insulin and epinephrine, as well as the effect of insulin on peripheral vascular sympathetic activity. This extended model represents a starting point from which further in silico investigations into the interaction between the autonomic nervous system and the metabolic control system can proceed. Features in PNEUMA 3.0 * Incorporates metabolic component based on prior models of glucose-insulin regulation and free fatty acid (FFA) regulation. * Changes in sympathetic activity from the autonomic portion of PNEUMA produce changes in epinephrine output, which in turn affects the metabolic sub-model. * Inputs from the dietary intake of glucose and external interventions, such as insulin injections, have also been incorporated. * Also incorporated is autonomic feedback from the metabolic component to the rest of PNEUMA: changes in insulin level lead to changes in sympathetic tone. System Requirements: PNEUMA requires Matlab R2007b or higher with the accompanying version of Simulink to be installed on your computer. | matlab, simulate, autoregulation, cardiovascular system, respiratory system, sleep-wake state, physiological intervention, pharmacological intervention, drug, breathing, heart rate, blood pressure, respiration, glucose, insulin, fatty acid, regulation, autonomic nervous system, chemoreflex, ventilation, circulation, cardiorespiratory, metabolic control system, circadian, regulation, epinephrine | has parent organization: Biomedical Simulations Resource | NIBIB P41-EB001978; NCRR P41-RR01861 |
PMID:17271149 | Free, Freely Available | nlx_152572 | SCR_001391 | 2026-08-12 10:48:23 | 3 | ||||||
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NIH Common Data Element Repository Resource Report Resource Website 1+ mentions |
NIH Common Data Element Repository (RRID:SCR_001390) | NIH CDE Resource Portal, CDE Resource Portal | data or information resource, narrative resource, standard specification, common data element | A repository of Common Data Elements (CDE). The CDE is a standardized, precisely defined question, paired with a set of allowable responses, used systematically across different sites, studies, or clinical trials to ensure consistent data collection. Multiple CDEs (from one or more Collections) can be curated into Forms. Forms in the Repository might be original, or might recreate the format of real-world data collection instruments or case report forms. NIH has endorsed collections of CDEs that meet established criteria. NIH-endorsed CDEs are designated with a gold ribbon. Users can Browse NIH-Endorsed CDEs, Browse All CDEs, or Browse Forms. | clinical research, clinical, patient registry, human subject research, human subject, data element, case report form, interoperability, data sharing | has parent organization: National Library of Medicine | Free, Freely Available | nlx_152564 | https://cde.nlm.nih.gov/home, http://www.nlm.nih.gov/cde/ | SCR_001390 | NIH Common Data Element (CDE) Resource Portal, Common Data Element (CDE) Resource Portal | 2026-08-12 10:48:23 | 8 | ||||||
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Intramodal Registration Software Resource Report Resource Website |
Intramodal Registration Software (RRID:SCR_001148) | data processing software, data analysis software, software resource, software application | Software that implements a set of C routines for robust, high-quality registration of two volumes, aligning according to a least-squares criterion which is well-suited to intramodal registration tasks. Programming skills are required to attach the ANSI-C routine to whichever system users have. It is available on Unix, Macintosh, and PC. | intramodal registration, unix, pc, macintosh, programming, c | has parent organization: Ecole Polytechnique Federale de Lausanne; Lausanne; Switzerland | Free, Available for download, Freely available | nif-0000-00318 | SCR_001148 | 2026-08-12 10:48:21 | 0 | |||||||||
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Simpleaffy Resource Report Resource Website 50+ mentions |
Simpleaffy (RRID:SCR_001302) | Simpleaffy | data processing software, data analysis software, software resource, software application | Software package that provides high level functions for reading Affy .CEL files, phenotypic data, and then computing simple things with it, such as t-tests, fold changes and the like. It makes heavy use of the affy library. It also has some basic scatter plot functions and mechanisms for generating high resolution journal figures. | affymetrix, annotation, data import, differential expression, microarray, one channel, preprocessing, quality control, report writing, transcription, visualization |
is listed by: OMICtools has parent organization: Bioconductor |
PMID:16076888 | GNU General Public License, v2 or newer | OMICS_02034 | SCR_001302 | Simpleaffy - Very simple high level analysis of Affymetrix data | 2026-08-12 10:48:22 | 85 | ||||||
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Open Colleges Interactive Brain Resource Report Resource Website 1+ mentions |
Open Colleges Interactive Brain (RRID:SCR_001427) | Open Colleges Interactive Brain | training material, atlas, narrative resource, data or information resource | Interactive infographic of a brain exploring more than 100,000 chemical reactions, highlighted by areas and explanations of what that area is known to do. | brain, chemical reaction | has parent organization: Open Colleges | Restricted | nlx_155867 | SCR_001427 | 2026-08-12 10:48:23 | 1 | ||||||||
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TOMUS Resource Report Resource Website |
TOMUS (RRID:SCR_001549) | TOMUS | data or information resource, resource, clinical trial, bibliography | Study that compared the outcomes of two minimally invasive surgical procedures to treat stress urinary incontinence in women. These procedures are called mid-urethral slings. The procedures insert a mesh sling or hammock to support the bladder neck so that urine does not leak. Both procedures have been approved by the FDA and have been shown to be safe and successful in treating stress urinary incontinence. However, it is not known if one is better than the other. This study answers that question. The secondary aims of the trial are to compare other outcomes for the two surgical procedures, including quality of life, sexual function, satisfaction with treatment outcomes, complications, and the need for other treatments(s) after surgery. Follow-up will be a minimum of two years. Stress urinary incontinence is the accidental leakage of urine during activities such as coughing, laughing, sneezing, or lifting heavy objects. | surgical procedure, female, mid-urethral sling, treatment, outcome, quality of life, sexual function, complication, retropubic mid-urethral sling, transobturator mid-urethral sling, adult human |
is listed by: ClinicalTrials.gov is listed by: NIDDK Information Network (dkNET) has parent organization: Urinary Incontinence Treatment Network |
Stress urinary incontinence, Urinary incontinence | NIDDK U01DK060401; NIDDK U01DK060379; NIDDK U01DK060397; NIDDK U01DK058234; NIDDK U01DK060393; NIDDK U01DK058229; NIDDK U01DK058225 |
PMID:20479459 PMID:22378483 PMID:21422865 PMID:21925636 PMID:23635737 |
Free, Freely available | nlx_152859 | SCR_001549 | Trial Of Mid-Urethral Slings, TOMUS-Trial Of Mid-Urethral Slings | 2026-08-12 10:48:25 | 0 | ||||
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Center for Gamma Ray Imaging Resource Report Resource Website |
Center for Gamma Ray Imaging (RRID:SCR_001384) | Center for Gamma-Ray Imaging | production service resource, material service resource, service resource, instrument manufacture | Biomedical technology resource center that develops new gamma-ray imaging instruments and techniques that yield substantially improved spatial and temporal resolutions. The Center makes its imagers and expertise available to a wide community of biomedical and clinical researchers through collaborative and service-oriented interactions. The collaborative research applies these new imaging tools to basic research in functional genomics, proteomics, cancer, cardiovascular disease and cognitive neuroscience, and to clinical research in tumor detection and other selected topics. There are five core research projects: * Detector technology research and development * Reconstruction algorithms and system modeling * Data acquisition, signal processing, and system development * Image-quality assessment and system optimization * Techniques for molecular imaging | spect, ct, imaging, clinical, gamma-ray, imaging instrument, basic research, functional genomics, cardiovascular disease, cognitive neuroscience, breast cancer, tumor detection, proteomics, cancer | has parent organization: University of Arizona; Arizona; USA | NIBIB EB002035-14 | nlx_152567 | SCR_001384 | 2026-08-12 10:48:23 | 0 | ||||||||
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NeuroMouse Database Resource Report Resource Website |
NeuroMouse Database (RRID:SCR_001143) | NeuroMouse | service resource, data or information resource, database, data repository, storage service resource, atlas | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 17, 2023.Toolbook(tm) based, interactive graphical database which provides structural, molecular, and genetic information on the adult murine nervous system; and its relevance to human neurobiology. This resource is primarily designed as a platform for users to interact, each sharing knowledge on their own area of expertise, which is compiled to a master database. This hypertext atlas presently comprises more than 1000 pages and is designed to provide a flexible integrated resource for the description and discussion of all forms mammalian neurologic data. Version 4.0 of the NeuroMouse program extends the program's basic framework to include a number of areas in modern molecular neurobiology. This system provides an integrated resource for the characterization and description of mammalian neurological data. Major divisions include: Neural Atlas, Molecular Atlas, Genetics/Surgical Lesion Atlas. Neuromouse has been integrated into our strain-specific three dimensional MRI and surgical atlases of the murine CNS. Database contents: Neural Atlas: - Rotational representation of the murine brain. - Neural structures: visual and alphabetic point and click index of neural structures, pathways and systems. - Brain atlas:photographic serial sections in the coronal, sagittal, and horizontal planes (average plate distance - 300 um). Physical brain distances are also provided as are meta-index grids to allow rapid movement between different planes and regions. # Catalog of primary and immortalized neural cells indexed to relevant neural structures. Molecular Atlas: - Index of neurotransmitters: Acetylcholine, GABA, Glutamate, Aspartate, Glycine, Dopamine, Norepinephrine, Epinephrine, Serotonin (synthesis, distribution, degradation, molecular modules, receptors, subunits, agonists, antagonists, gene structure, localization, physical properties and transgenics are indicated for each item). - Index of neurotrophins / neurokines: NGF, BDNF, NT-3, NT-4/5, CNTF, LIF, Onostain M, IL-6, GDNF, FGF's, S100b (ligand, receptors, expression pattern, physical properties, homologous factors, transgenics/knockouts, chromosomal location, effects of agent, and effects of factors on agent are indicated for each item). - Index of additional neural agents: Bcl-2, TNF/Fas, TGF-beta, P53/Rb, PDGF, EGF family (ligand, receptor, expression patterns, physical properties, homologous factors, transgenics/ knockouts, chromosomal location, effects of agent, effects of factors on agent are indicated for each item). - Molecular biology: Molecular biology of important neural genes with integrated l links, plus selected neural topics (ex. programmed cell death, inducible gene systems, protein motifs, neural gene elements, and selected signal transduction pathways). Genetics Atlas: - Lesion paradigms: Index of common neuronal structural and chemical lesion paradigms. - Selected procedures: description of common neurosurgical, cell tracing, culturing and laboratory procedures. - Neurologic syndromes: Index of important human neurologic syndromes and appropriate animals models. - Neural mutant database: Index and description of naturally occurring and genetically modified murine neurologic mutations; including pages on double knockout animals. Interactive maps of each murine chromosome and human syntenic maps. | epinephrine, gaba, acetylcholine, agonist, antagonist, aspartate, dopamine, glutamate, glycine, human, molecular biology, murine chromosome, mutant, neural, neural factor, neurokine, neurological, neurotransmitter, n eurotrophin, norepinephrine, serotonin, molecular neuroanatomy resource, nervous system, adult, murine | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-11000 | SCR_001143 | 2026-08-12 10:48:20 | 0 | |||||||||
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Semantic Measures Library Resource Report Resource Website |
Semantic Measures Library (RRID:SCR_001383) | SML | software library, software toolkit, software resource | Open source Java library dedicated to semantic measures computation and analysis. Tools based on the SML are also provided through the SML-Toolkit, a command line software giving access to some of the functionalities of the library. The SML and the toolkit can be used to compute semantic similarity and semantic relatedness between semantic elements (e.g. concepts, terms) or entities semantically characterized (e.g. entities defined in a semantic graph, documents annotated by concepts defined in an ontology). | semantic measure, semantic similarity, semantic relatedness, functional similarity, gene ontology, annotation, parse, gene, disease ontology, mesh, rdf, owl, umls, snomed-ct, java, semantic, command line |
is listed by: FORCE11 is listed by: Gene Ontology Tools is related to: Gene Ontology has parent organization: Ecole des Mines d'Ales; Ales; France |
Ecole des Mines d'Ales; Ales; France ; LGI2P Research Center |
PMID:24108186 | Free, Available for download, Freely available | nlx_152555 | http://www.semantic-measures-library.org | SCR_001383 | SML-Toolkit, Semantic Measures Library and ToolKit, Semantic Measures Library & ToolKit | 2026-08-12 10:48:23 | 0 | ||||
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CODR: C PATH On Line Data Repository Resource Report Resource Website 1+ mentions |
CODR: C PATH On Line Data Repository (RRID:SCR_001388) | CODR | service resource, data or information resource, production service resource, database, data repository, analysis service resource, storage service resource, data analysis service | A repository of de-identified control arm data of patients from clinical studies of Alzheimer's disease and Mild Cognitive Impairment. It provides the ability to analyze the data online with the R statistical analysis program, create and download standard reports, run complex queries, or download data to a desktop for further analysis. Additional data will be added to the database over time. Critical Path Institute consortia members and qualified researchers may upload and work on scientific data relevant to biomarkers of drug toxicity, neurodegenerative diseases, and patient-reported outcomes. | clinical data, alzheimer's disease, camd, biomarker, drug toxicity, neurodegenerative disease, patient-reported outcome, patient outcome, metadata standard, data repository | has parent organization: CAMD | Neurodegenerative disease, Drug toxicity, Alzheimer's disease, Mild Cognitive Impairment | Free, Freely Available | nlx_152562 | SCR_001388 | C-Path Online Data Repository (CODR), CPATH online data repository, C-PATH Online Data Repository, C PATH On Line Data Repository | 2026-08-12 10:48:23 | 2 | ||||||
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SISTEr Resource Report Resource Website 100+ mentions |
SISTEr (RRID:SCR_001542) | SISTEr | data or information resource, resource, data set, clinical trial | Clinical trial under the Urinary Incontinence Treatment Network to compare the treatment success for two surgical procedures that are frequently used and have similar cure rates, yet have not been compared directly to each other in a large, rigorously conducted randomized trial. The secondary aims of the trial are to compare other outcomes for the two surgical procedures, including quality of life, sexual function, satisfaction with treatment outcomes, complications, and need for other treatment(s) after surgery. Follow-up will be a minimum of two years and up to four years. | urinary, incontinence, dataset, surgical procedure, outcome, quality of life, sexual function, satisfaction, treatment, complication, burch procedure, sling procedure, female, surgery |
is listed by: NIDDK Information Network (dkNET) has parent organization: Urinary Incontinence Treatment Network |
Urinary incontinence, Stress, Stress urinary incontinence | NIDDK ; NICHD |
Free, Freely available | nlx_152852 | http://www.uitn.net/sister.asp | SCR_001542 | Stress Incontinence Surgical Treatment Efficacy Trial | 2026-08-12 10:48:25 | 151 | ||||
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CAMD Resource Report Resource Website 1+ mentions |
CAMD (RRID:SCR_001389) | CAMD | data or information resource, portal, consortium, organization portal | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 8, 2022. Consortium developing new technologies and methods to accelerate the development and review of medical products for neurodegenerative diseases. It is focused on accelerating drug development for patients with chronic neurodegenerative disease, namely, Alzheimer's disease (AD) and Parkinson's disease (PD), by advancing drug development tools for evaluating drug efficacy, conducting clinical trials, and streamlining the process of regulatory review. The consortium focuses on sharing precompetitive patient-level data from the control arms of legacy clinical trials, developing new tools to be submitted to the regulatory agencies, and developing consensus data standards. CAMD has the following areas of focus: (1) qualification of biomarkers, (2) development of common data standards, (3) creation of integrated databases for clinical trials data, and (4) development of quantitative model-based tools for drug development. Regulatory milestones include a qualification opinion with EMA for the use of low baseline hippocampal volume for patient enrichment in pre-dementia trials, and most recently, positive regulatory decisions from the FDA and EMA for the use of a clinical trial simulation tool to aid in trials for mild to moderate stages of AD., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. | data set, clinical trial, mild cognitive impairment, clinical, biomarker, metadata standard, disease progression model, consortium, drug, data sharing, disease modeling, drug development, disease model, imaging, cerebral spinal fluid |
is listed by: Consortia-pedia has parent organization: Critical Path Institute; Arizona; USA is parent organization of: CODR: C PATH On Line Data Repository |
Publicly funded | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_152563 | SCR_001389 | Coalition Against Major Diseases | 2026-08-12 10:48:23 | 6 | ||||||
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Mutascope Resource Report Resource Website 1+ mentions |
Mutascope (RRID:SCR_001265) | Mutascope | data processing software, data analysis software, software resource, software application | Software suite to analyze data from high throughput sequencing of PCR amplicons, with an emphasis on normal-tumor comparison for the accurate and sensitive identification of low prevalence mutations. | high throughput sequencing, pcr amplicon, pcr, mutation, amplicon, sequencing, somatic variant |
is listed by: OMICtools has parent organization: SourceForge |
Tumor, Normal | PMID:23712659 | Free, Public | OMICS_02074 | SCR_001265 | Mutascope - Analysis software designed for PCR-amplicon sequencing data | 2026-08-12 10:48:22 | 4 | |||||
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Mugsy Resource Report Resource Website 50+ mentions |
Mugsy (RRID:SCR_001414) | sequence analysis software, software application, data processing software, software resource, data analysis software | Software resource for multiple whole genome alignment. It uses Nucmer, a custom graph-based segmentation procedure, for pairwise alignment, and the Seqan:TCoffee's multiple alignment strategy. | software, genome, genome alignment, segmentation, pairwise alignment, sequence analysis software |
is listed by: OMICtools is listed by: Debian has parent organization: SourceForge |
PMID:21148543 DOI:10.1093/bioinformatics/btq665 |
Free, Available for download, Freely available | OMICS_03606 | https://sources.debian.org/src/mugsy/ | SCR_001414 | 2026-08-12 10:48:23 | 75 | |||||||
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Immune Tolerance Network (ITN) Resource Report Resource Website 10+ mentions |
Immune Tolerance Network (ITN) (RRID:SCR_001535) | ITN | portal, data or information resource, funding resource, clinical trial, topical portal | International clinical research consortium dedicated to the clinical evaluation of novel tolerogenic approaches for the treatment of autoimmune diseases, asthma and allergic diseases, and the prevention of graft rejection. They aim to advance the clinical application of immune tolerance by performing high quality clinical trials of emerging therapeutics integrated with mechanism-based research. In particular, they aim to: * Establish new tolerance therapeutics * Develop a better understanding of the mechanisms of immune function and disease pathogenesis * Identify new biomarkers of tolerance and disease Their goals are to identify and develop treatment game changers for tolerance modulating therapies for the treatment of immune mediated diseases and disabling conditions, and to conduct high quality, innovative clinical trials and mechanistic studies not likely to be funded by other sources or to be conducted by private industry that advance our understanding of immunological disorders. In the Immune Tolerance Network's (ITN) unique hybrid academic/industry model, the areas of academia, government and industry are integral to planning and conducting clinical studies. They develop and fund clinical trials and mechanistic studies in partnership. Their development model is a unique, interactive process. It capitalizes on their wide-ranging, multidisciplinary expertise provided by an advisory board of highly respected faculty from institutions worldwide. This model gives investigators special insight into developing high quality research studies. The ITN is comprised of leading scientific and medical faculty from more than 50 institutions in nine countries worldwide and employs over 80 full-time staff at the University of California San Francisco (UCSF), Bethesda, Maryland and Benaroya Research Institute in Seattle, Washington. | immune tolerance, prevent, cure, disease, multiple sclerosis, therapy, biomarker, transplant |
is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources is related to: Immune Tolerance Network TrialShare has parent organization: Benaroya Research Institute |
Type 1 diabetes, Diabetes, Allergy, Asthma, Autoimmune disease, Transplantation, Immunological disorder | NIAID N01AI15416 | nlx_152838 | SCR_001535 | 2026-08-12 10:48:25 | 15 | |||||||
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HALT-C Trial Resource Report Resource Website |
HALT-C Trial (RRID:SCR_001534) | HALT-C Trial, HALT-C | data or information resource, resource, clinical trial, bibliography | Multi-center, randomized controlled study designed to determine if continuing interferon long term over several years will suppress the Hepatitis C virus, prevent progression to cirrhosis, prevent liver cancer and reduce the need for liver transplantation. Patient enrollment began in 2000 and was completed in 2003 at 10 clinical centers, which were supported by a data coordinating center, virological testing center, and central sample repository. Patients with chronic hepatitis C and advanced fibrosis or cirrhosis on liver biopsy who failed to respond to a previous course of interferon alfa were enrolled in this study. Patients were initially treated with a 24-week course of peginterferon alfa-2a and ribavirin. Patients who remained hepatitis C virus RNA positive were then randomized to receive maintenance, low-dose peginterferon or to be followed on no treatment. Liver biopsies were done before enrollment and after 2 and 4 years of treatment or follow-up. The endpoints were development of cirrhosis, hepatic decompensation, hepatocellular carcinoma, death, or liver transplantation. 1050 patients were randomized and followed through the 4 year randomized phase of the trial and as long as 4 years off treatment. Serum samples collected at multiple time points, DNA and liver tissue are available for scientific investigation. | interferon, progression, cirrhosis, prevention, liver cancer, liver transplantation, liver, pegylated interferon, clinical, outcome, adult human, dna, liver tissue, serum, blood, b lymphoblastoid cell-line, epstein-barr virus infection in peripheral blood mononuclear cell, peripheral blood mononuclear cell, biomaterial supply resource, formalin fixed, histology, frozen, stained liver slide, unstained liver slide, advanced fibrosis, liver biopsy, peginterferon alfa-2a, ribavirin |
is listed by: One Mind Biospecimen Bank Listing is listed by: ClinicalTrials.gov is listed by: NIDDK Central Repository is listed by: NIDDK Research Resources is listed by: NIDDK Information Network (dkNET) |
Hepatitis C virus, Chronic hepatitis C | NIDDK | Free, Freely available | nlx_152835 | http://archives.niddk.nih.gov/haltctrial/displaypage.aspx?pagename=haltctrial/index.htm | http://www.haltctrial.org/ | SCR_001534 | Hepatitis C Antiviral Long-term Treatment against Cirrhosis, Hepatitis C Antiviral Long-term Treatment against Cirrhosis (HALT-C) Trial, Hepatitis C Antiviral Long-term Treatment against Cirrhosis Trial | 2026-08-12 10:48:25 | 0 |
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