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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Crystallography and NMR System (CNS)
 
Resource Report
Resource Website
1+ mentions
Crystallography and NMR System (CNS) (RRID:SCR_014223) CNS data processing software, software application, data visualization software, software toolkit, software resource Software designed to provide a multi-level hierachical approach for the most commonly used algorithms in macromolecular structure determination. Features include heavy atom searching, experimental phasing (including MAD and MIR), density modification, crystallographic refinement with maximum likelihood targets, and NMR structure calculation using NOEs, J-coupling, chemical shift, and dipolar coupling data. Modules, libraries, utility programs, tutorials, and a syntax manual are available on the website. structure determination, software suite, macromolecular structure determination, data visualization software, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Yale University; Connecticut; USA
PMID:9757107 Available to academic institutions, Request form must be submitted biotools:cnssolve https://bio.tools/cnssolve SCR_014223 Crystallography and NMR System 2026-08-05 10:46:08 8
ImageMagick
 
Resource Report
Resource Website
100+ mentions
ImageMagick (RRID:SCR_014491) data processing software, software application, software resource, image processing software Software suite for creating, editing, composing, and converting bitmap images. It can read and write images in over 200 formats including PNG, JPEG, JPEG-2000, GIF, TIFF, DPX, EXR, WebP, Postscript, PDF, and SVG. The user can use this software to resize, flip, mirror, rotate, distort, shear and transform images, adjust image colors, apply various special effects, or draw text, lines, polygons, ellipses and Bézier curves. image editing, image processing software, image analysis software, bitmap, adjust image colors, bezier curves is listed by: Debian Restricted https://sources.debian.org/src/imagemagick/ SCR_014491 2026-08-05 10:46:07 133
I-TASSER
 
Resource Report
Resource Website
1000+ mentions
I-TASSER (RRID:SCR_014627) software resource, data processing software, software application, data analysis software Web server as integrated platform for automated protein structure and function prediction. Used for protein 3D structure prediction. Resource for automated protein structure prediction and structure-based function annotation. Automated prediction, protein structure prediction, protein function prediction, protein 3D structure, amino acid sequence, alignment, simulation, 3D atomic model, protein, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: University of Michigan; Ann Arbor; USA
has parent organization: University of Kansas; Kansas; USA
NIGMS GM083107;
NIGMS GM084222
DOI:10.1186/1471-2105-9-40
DOI:10.1093/nar/gkv342
PMID:20360767
PMID:18215316
Free, Available for download, Freely available biotools:i-tasser, SCR_018803 https://bio.tools/i-tasser SCR_014627 Iterative Threading Assembly Refinement, Iterative Threading ASSEmbly Refinement 2026-08-05 10:46:09 3702
Cufflinks
 
Resource Report
Resource Website
5000+ mentions
Cufflinks (RRID:SCR_014597) data processing software, software application, sequence analysis software, data analysis software, software resource Software tool for transcriptome assembly and differential expression analysis for RNA-Seq. Includes script called cuffmerge that can be used to merge together several Cufflinks assemblies. It also handles running Cuffcompare as well as automatically filtering a number of transfrags that are likely to be artifacts. If the researcher has a reference GTF file, the researcher can provide it to the script to more effectively merge novel isoforms and maximize overall assembly quality. transcriptome, rna-seq, rna seq, cuffmerge, cufflink, cuffcompare, transfrags, artifacts, gtf file, transcriptome assembly, expression analysis, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
works with: GeneScissors
is hosted by: GitHub
DOI:10.1038/nbt.1621 Acknowledgement requested, Source code available on GitHub biotools:cufflinks, OMICS_01304, SCR_013307 https://github.com/cole-trapnell-lab/cufflinks, https://bio.tools/cufflinks, https://sources.debian.org/src/cufflinks/ SCR_014597 2026-08-05 10:46:11 8838
SPEX2
 
Resource Report
Resource Website
1+ mentions
SPEX2 (RRID:SCR_014923) data processing software, software application, sequence analysis software, data analysis software, software resource Automatic software program for profiling spatial gene expression patterns from Fly embryo ISH images. It utilizes image-based genome-scale profiling of whole-body mRNA patterns. software, spatial gene expression, fly, embryo, extraction, mrna, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Carnegie Mellon University; Pennsylvania; USA
PMID:20529936 biotools:spex2 https://bio.tools/spex2 SCR_014923 2026-08-05 10:46:13 1
RepeatScout
 
Resource Report
Resource Website
500+ mentions
RepeatScout (RRID:SCR_014653) data processing software, algorithm resource, software application, data analysis software, sequence analysis software, software resource Algorithm used to identify de novo repeat families in newly sequenced genomes. Repeat libraries for C. briggsae, M. muscles (X chromosome), R. novegicus (X chromosome), armadillo, H. sapiens (X chromosome), and various other mammals created using RepeatScout are available on the main site., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. algorithm, sequence analysis, repeat, genome sequence, de novo, repeat family, repeat library, bio.tools is used by: RepeatModeler
is listed by: Debian
is listed by: bio.tools
has parent organization: University of California at San Diego; California; USA
PMID:15961478 THIS RESOURCE IS NO LONGER IN SERVICE BioTools:RepeatScout, biotools:RepeatScout https://bio.tools/RepeatScout, https://bio.tools/RepeatScout, https://bio.tools/RepeatScout SCR_014653 2026-08-05 10:46:10 815
Online Resource for Community Annotation of Eukaryotes
 
Resource Report
Resource Website
10+ mentions
Online Resource for Community Annotation of Eukaryotes (RRID:SCR_014989) OrcAE, ORCAE data or information resource, wiki, narrative resource Online genome annotation tool for validating and correcting gene annotations. OrcAE is community-driven and can be edited by account-holders in the research community. genome annotation, gene validation, community driven, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Bioinformatics Gent
has parent organization: Ghent University; Ghent; Belgium
has parent organization: VIB; Flanders; Belgium
PMID:23132114 Free, Account required, The research community can contribute to this resource biotools:orcae https://bio.tools/orcae SCR_014989 Online Resource for Community Annotation of Eukaryotes (OrcAE) 2026-08-05 10:46:14 16
libRoadRunner
 
Resource Report
Resource Website
10+ mentions
libRoadRunner (RRID:SCR_014763) software application, simulation software, software resource Simulation engine for systems and synthetic biology to be used with other software applications. It retains the original functionality of RoadRunner but has changes in performance, back-end design, event handling, new C++ API, and stochastic simulation support. simulation engine, simulation software, road runner, roadrunner, systems biology, synthetic biology is listed by: Debian
is listed by: OMICtools
NIGMS GM081070 DOI:10.1093/bioinformatics/btv363 Open source, Available for download OMICS_09368 https://sources.debian.org/src/libroadrunner-dev/ SCR_014763 2026-08-05 10:46:12 11
Prokka
 
Resource Report
Resource Website
1000+ mentions
Prokka (RRID:SCR_014732) data processing software, software application, sequence analysis software, data analysis software, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software tool for the rapid annotation of prokaryotic genomes. It produces GFF3, GBK and SQN files that are ready for editing in Sequin and ultimately submitted to Genbank/DDJB/ENA. A typical 4 Mbp genome can be fully annotated in less than 10 minutes on a quad-core computer, and scales well to 32 core SMP systems., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. annotation, prokaryote, genome, prokaryotic genome, sequence analysis software, annotation software, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1093/bioinformatics/btu153 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04220, biotools:prokka https://bio.tools/prokka, https://sources.debian.org/src/prokka/, https://sources.debian.org/src/prokka/ SCR_014732 2026-08-05 10:46:11 4876
MeroX
 
Resource Report
Resource Website
50+ mentions
MeroX (RRID:SCR_014956) data processing software, software application, sequence analysis software, data analysis software, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 29,2023. Software tool for the analysis of cross-linking/mass spectrometry datasets using MS-cleavable cross-linkers. MeroX is specialized for MS/MS-cleavable cross linking reagents and identifies the specific fragmentation products of the cleavable cross links. sequence analysis software, cross linking, mass spectrometry, MS cleavage, fragmentation, cleavable cross link, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: StavroX
PMID:25261217 THIS RESOURCE IS NO LONGER IN SERVICE BioTools:MeroX, biotools:MeroX https://bio.tools/MeroX, https://bio.tools/MeroX, https://bio.tools/MeroX SCR_014956 2026-08-05 10:46:15 74
Lifebit Deploit
 
Resource Report
Resource Website
1+ mentions
Lifebit Deploit (RRID:SCR_016428) data management software, software application, software resource, data analysis service, production service resource, service resource, analysis service resource Platform for computing management for data analysis on the cloud from the Lifebit company. Allows the computational analyses to be permanently linked to live analyses pipelines. Lifebit, compute, management, data, analysis, cloud, integrate, data, reproduce, transparent, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:28398311 Commercially available biotools:nextflow https://bio.tools/nextflow SCR_016428 2026-08-05 10:46:38 2
Microscopy Image Browser
 
Resource Report
Resource Website
100+ mentions
Microscopy Image Browser (RRID:SCR_016560) MIB data processing software, software application, data visualization software, data analysis software, standalone software, software resource, image processing software Software package for advanced image processing, analysis, segmentation and visualization of multi-dimensional (2D-4D) light and electron microscopy datasets. segmentation, analysis, multidimentional, dataset, light, electron, microscopy, image, processing, visualization, data, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: MATLAB
Biocenter Finland ;
Biological Imaging Network Academy of Finland ;
University of Helsinki
PMID:26727152 Free, Available for download, Freely available biotools:mib https://www.youtube.com/watch?v=I9FWmJX_nl0&index=1&list=PLGkFvW985wz8cj8CWmXOFkXpvoX_HwXzj, https://bio.tools/mib SCR_016560 MIB, Microscopy Image Browser 2026-08-05 10:46:36 143
DINIES
 
Resource Report
Resource Website
1+ mentions
DINIES (RRID:SCR_016505) DINIES data processing software, web application, software application, data analysis software, sequence analysis software, software resource Web server for predicting unknown drug-target interaction networks from various types of biological data in the framework of supervised network inference. predict, drug, target, interaction, network, biological, data, chemical, structure, protein, amino acid, sequence, domain, bio.tools is listed by: GenomeNet
is listed by: Debian
is listed by: bio.tools
is related to: KEGG
has parent organization: Kyoto University; Kyoto; Japan
Ministry of Education ;
Culture ;
Sports ;
Science and Technology of Japan ;
the Japan Science and Technology Agency ;
the Japan Society for the Promotion of Science
PMID:24838565 Free, Freely available biotools:dinies https://bio.tools/dinies SCR_016505 Drug target Interaction Network Inference Engine based on Supervised analysis 2026-08-05 10:46:36 4
TB PORTALS
 
Resource Report
Resource Website
10+ mentions
TB PORTALS (RRID:SCR_016594) data or information resource, data repository, portal, consortium, disease-related portal, topical portal, organization portal, storage service resource, service resource Web based open access platform for global drug resistant tuberculosis data sharing and analysis. The NIAID TB Portals program and consortium of clinicians and scientists from countries with a heavy burden of TB, especially drug resistant TB, to collect TB data. collect, data, sharing, analysis, tuberculosis, global, bio.tools is listed by: NIAID
is listed by: bio.tools
is listed by: Debian
tuberculosis NIH DOI:10.1128/JCM.01013-17 Free, Freely available r3d100013925, biotools:TB_Portals https://bio.tools/TB_Portals, https://doi.org/10.17616/R31NJN8L SCR_016594 2026-08-05 10:46:41 12
Libra
 
Resource Report
Resource Website
Libra (RRID:SCR_016608) data processing software, software application, data analysis software, sequence analysis software, software resource, data analytics software Hadoop based tool for massive comparative metagenomics analysis. Compute the similarity between metagenomic samples. gene, distance, matrix, computation, k-mer-based, sequence, comparison, Hadoop, metagenomic, sample, bio.tools is listed by: bio.tools
is listed by: Debian
NSF 1640775 Free, Available for download, Freely available biotools:Libra_k-mer https://bio.tools/Libra_k-mer SCR_016608 2026-08-05 10:46:37 0
MentaLiST
 
Resource Report
Resource Website
1+ mentions
MentaLiST (RRID:SCR_016469) data processing software, software application, sequence analysis software, data analysis software, software resource Software for a MLST (multi-locus sequence typing) caller, based on a k-mer counting algorithm and written in the Julia language. Designed and implemented to handle large typing schemes. next, generation, sequencing, multi, locus, sequence, typing, pathogen, surveillance, gene, identify, strain, type, housekeeping, whole, genome, sequencing, data, bacteria, genotyping, bio.tools is listed by: bio.tools
is listed by: Debian
Canadian Institute for Health Research ;
Genome Canada ;
Genome BC
PMID:29319471 Free, Available for download, Freely available biotools:mentalist https://bio.tools/mentalist SCR_016469 2026-08-05 10:46:39 8
cisTEM
 
Resource Report
Resource Website
50+ mentions
cisTEM (RRID:SCR_016502) cisTEM data processing software, software application, software resource, image processing software Software to process cryo-EM images of macromolecular complexes and obtain high-resolution 3D reconstructions from them. data, processing, high, resolution, electron, cryo, macroscopy, single, particle, averaging, image, macromolecule, high, resolution, 3D, bio.tools is listed by: bio.tools
is listed by: Debian
Howard Hughes Medical Institute DOI:10.7554/eLife.35383 Open source, Trial available biotools:cistem https://bio.tools/cistem SCR_016502 computational imaging system for Transmission Electron Microscopy 2026-08-05 10:46:35 64
kallisto
 
Resource Report
Resource Website
100+ mentions
kallisto (RRID:SCR_016582) software resource, data processing software, software application, data analysis software Software tool for quantifying abundances of transcripts from RNA-Seq data or target sequences using high-throughput sequencing reads. bio.tools is listed by: Debian
is listed by: bio.tools
works with: sleuth
works with: kb_python
PMID:27043002 Free, Available for download, Freely available biotools:kallisto https://pachterlab.github.io/kallisto/download.html, https://bio.tools/kallisto, https://sources.debian.org/src/kallisto/ SCR_016582 kallisto v0.43.1 2026-08-05 10:46:36 127
Pavian
 
Resource Report
Resource Website
10+ mentions
Pavian (RRID:SCR_016679) web application, software resource, data analysis service, production service resource, service resource, analysis service resource Software R package for interactive analysis of metagenomics classification results with a special focus on infectious disease diagnosis. Used for analyzing and visualization of metagenomics classification results from classifiers such as Kraken, Centrifuge and MetaPhlAn. Provides an alignment viewer for validation of matches to a particular genome. interactive, analysis, metagenomics, classification, result, infectious, disease, diagnosis, data, visualization, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Centrifuge Classifier
NHGRI R01 HG006677;
NIGMS R01 GM083873;
U. S. Army Research Office W911NF1410490
DOI:10.1101/084715 Free, Freely available biotools:pavian https://fbreitwieser.shinyapps.io/pavian/, https://bio.tools/pavian SCR_016679 2026-08-05 10:46:43 22
Centrifuge Classifier
 
Resource Report
Resource Website
1+ mentions
Centrifuge Classifier (RRID:SCR_016665) data processing software, software application, sequence analysis software, data analysis software, software resource Software for rapid and sensitive classification of metagenomic sequences. Used for the classification of DNA sequences from microbial samples and analysis of large metagenomics data sets on conventional desktop computers. classification, large, metagenomic, sequence, DNA, microbial, sample, analysis, data, desktop, computer, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is related to: Pavian
has parent organization: Center for Computational Biology at JHU
U. S. Army Research Office W911NF1410490;
NSF ABI1356078;
NHGRI R01 HG006677;
NIGMS R01 GM083873
DOI:10.1101/gr.210641.116 Free, Available for download, Freely available biotools:centrifuge, OMICS_12217 https://github.com/infphilo/centrifuge, https://bio.tools/centrifuge, https://sources.debian.org/src/centrifuge/ SCR_016665 2026-08-05 10:46:43 9

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