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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Brain Imaging Data Structure (BIDs)
 
Resource Report
Resource Website
100+ mentions
Brain Imaging Data Structure (BIDs) (RRID:SCR_016124) BIDS data or information resource, narrative resource, portal, standard specification Standard specification for organizing and describing outputs of neuroimaging experiments. Used to organize and describe neuroimaging and behavioral data by neuroscientific community as standard to organize and share data. BIDS prescribes file naming conventions and folder structure to store data in set of already existing file formats. Provides standardized templates to store associated metadata in form of Javascript Object Notation (JSON) and tab-separated value (TSV) files. Facilitates data sharing, metadata querying, and enables automatic data analysis pipelines. System to curate, aggregate, and annotate neuroimaging databases. Intended for magnetic resonance imaging data, magnetoencephalography data, electroencephalography data, and intracranial encephalography data. Data storing structure, neuroimaging, standardized template, data sharing, MRI data, MEG data, EEG data, iEEG data, FASEB list is used by: OpenNeuro
is used by: SPARC Portal
is used by: SPARC Data Standard
is listed by: FAIRsharing
is related to: BIDS-Matlab
is related to: NiPoppy
works with: MNE-BIDS
International Neuroinformatics Coordinating Facility ;
Laura and John Arnold Foundation ;
NIGMS P20 GM103472;
Wellcome Trust ;
NIAAA U01 AA021697;
NIMH Intramural Research Program ;
German federal state of Sachsen-Anhalt ;
European Regional Development Fund ;
Medical Research Council United Kingdom ;
NSF 1429999
PMID:27326542
PMID:29917016
PMID:31239435
PMID:31239438
PMID:37744469
Free, Freely available https://bids-specification.readthedocs.io/en/stable/, https://doi.org/10.25504/FAIRsharing.rd1j6t SCR_016124 Brain Imaging Data Structure, BIDS, Brain Imaging Data Structure (BIDS), Brain Imaging Data Structure v1.4.0 2026-08-12 10:51:20 235
InterLex
 
Resource Report
Resource Website
1+ mentions
InterLex (RRID:SCR_016178) ontology, data or information resource, narrative resource, controlled vocabulary, wiki The InterLex project - a core component of SciCrunch and supported by projects such as the Neuroscience Information Framework project (NIF), the NIDDK Information Network (dkNET), and the Open Data Commons for Spinal Cord Injury - is a dynamic lexicon of biomedical terms. Unlike an encyclopedia, a lexicon provides the meaning of a term, and not all there is to know about it. InterLex is being constructed to help improve the way that biomedical scientists communicate about their data, so that information systems like NIF and dkNET can find data more easily and provide more powerful means of integrating that data across distributed resources. One of the big roadblocks to data integration in the biomedical sciences is the inconsistent use of terminology in databases and other resources such as the literature. When we use the same terms to mean different things, we cannot easily ask questions that span across multiple resources. For example, if three databases have information about what genes are expressed in cortex, but they all use different definitions of cerebral cortex, then it is hard to compare them. InterLex allows for the association of data values (i.e. the value of a field or text within a field) to terminologies enabling the crowdsourcing of data-terminology mappings. InterLex was built on the foundation of NeuroLex (see Larson and Martone 2013 Neurolex: An online framework for neuroscience knowledge. Frontiers in Neuroinformatics, 7:18) and contains all of the existing NeuroLex terms. The initial entries in NeuroLex were built from the NIFSTD ontologies. NIFSTD currently has about 60,000 concepts (includes both classes and synonyms) that span gross anatomy, cells, subcellular structures, diseases, functions and techniques. InterLex models terms using primitives of the Web Ontology Language (OWL) and can export directly to a variety of standard ontology formats. A primary goal of interlex is to provide a stable layer on top of the many other existing terminologies, lexicons, and ontologies (i.e. provide a way to federate ontologies for data applications) and to provide a set of inter-lexical and inter-data-lexical mappings. In the future, InterLex will support user specific namespaces so that users can customize the exact definitions or ontologies they source from, as well as the relationships on those terms. Importantly, however, InterLex enforces a simple rule which is that terms which represent the same concept under the same superclass will maintain the same identifier fragment (i.e. 'ilx_1234567'). However, each user will be able to 'fork' a term into their own namespace (e.g. http://uri.interlex.org/user/ilx_1234567). This enables the various perspectives on a term or concept to have equal space so that the full diversity of views on a term can be seen and expressed. Sign-up for updates to get notified about updates to InterLex and when new features are available. terminology, lexicon, vocabulary is used by: SPARC Portal
is related to: NeuroLex
is related to: NIFSTD
has parent organization: SciCrunch
https://scicrunch.org/scicrunch/interlex/dashboard SCR_016178 2026-08-12 10:51:31 6
PDB-Dev
 
Resource Report
Resource Website
10+ mentions
PDB-Dev (RRID:SCR_016185) service resource, data repository, storage service resource Data repository for integrative/hybrid structural models of macromolecules and their assemblies. This includes atomistic models as well as multi-scale models consisting of different coarse-grained representations. protein, prototype, deposition, integration, hybrid, model, macromolecule, assembly, crystallography, spectroscopy, microscopy, is related to: IHM-dictionary
has parent organization: Worldwide Protein Data Bank (wwPDB)
has parent organization: Rutgers University; New Jersey; USA
NSF DBI-1519158 Account required, Freely available, The research community can contribute to this resource SCR_016185 2026-08-12 10:51:21 36
Vensim
 
Resource Report
Resource Website
10+ mentions
Vensim (RRID:SCR_016394) simulation software, software resource, software application Simulation software for improving the performance of real systems. Used for developing, analyzing, and packaging dynamic feedback models. performance, system, Ventana Systems Inc, model, modelling, analysis Commercially available, Available for purchase SCR_016394 2026-08-12 10:51:33 14
MacroModel
 
Resource Report
Resource Website
100+ mentions
MacroModel (RRID:SCR_016747) simulation software, software resource, software application Software package for molecular modeling. Computes free energy changes using free energy perturbation method. Used to examine molecular conformations, molecular motion, and intermolecular interactions, such as those in a ligand-receptor complex. molecular, modeling, free, energy, changes, perturbation, method, conformation, motion, interaction, ligand, receptor, complex has parent organization: Schrodinger Commercially available, Free version available https://en.freedownloadmanager.org/Windows-PC/MacroModel.html SCR_016747 2026-08-12 10:51:35 138
Shape screening
 
Resource Report
Resource Website
1+ mentions
Shape screening (RRID:SCR_016750) simulation software, software resource, software application Software tool for shape-based superposition and similarity searching. Identifies new compounds with shapes (and, if desired, other properties) that are similar to the known binder. shape, based, superposition, search, new, compound has parent organization: Schrodinger Commercially available SCR_016750 2026-08-12 10:51:38 3
PICRUSt
 
Resource Report
Resource Website
10+ mentions
PICRUSt (RRID:SCR_016855) PICRUSt simulation software, software resource, software application Software package to predict metagenome functional content from marker gene (e.g., 16S rRNA) surveys and full genomes. Used to predict which gene families are present and then combines gene families to estimate the composite metagenome. predict, metagenome, functional, content, DNA, sample, marker, gene, sequence, data, microbiome, 16S, RNA is related to: PICRUSt2 Canadian Institutes of Health Research ;
Canada Research Chairs program ;
Howard Hughes Medical Institute ;
NIDDK P01 DK078669;
NHGRI U01 HG004866;
NHGRI R01 HG004872;
Crohn’s and Colitis Foundation of America ;
Sloan Foundation ;
NHGRI R01 HG005969;
NSF CAREER DBI1053486;
ARO W911NF1110473
PMID:23975157 Free, Available for download, Freely available SCR_016856 SCR_016855 Phylogenetic Investigation of Communities by Reconstruction of Unobserved States, PICRUSt 2026-08-12 10:51:39 45
Minimum Information for Biological and Biomedical Investigations
 
Resource Report
Resource Website
1+ mentions
Minimum Information for Biological and Biomedical Investigations (RRID:SCR_002042) MIBBI data or information resource, narrative resource, standard specification A common portal for minimum information (MI) checklists to act as a one-stop shop for those exploring the range of extant projects, foster collaborative development and ultimately promote gradual integration. Goals include * To increase the visibility of projects developing guidance for the reporting of biological and biomedical science. * To encourage appropriate collaborative development between projects to avoid duplication of effort or competition. * To promote the adoption of consensus guidance on reporting by journals and funders. minimum information, bioscience, metadata standard, MDAR lists: MIAPA
lists: Minimum Information About a Simulation Experiment
is listed by: FORCE11
is related to: Genomic Standards Consortium
is related to: MIGen
has parent organization: FAIRsharing
BBSRC BB/E025080/1 PMID:18688244 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-12075 http://www.mibbi.org/, http://mibbi.sourceforge.net/, https://www.force11.org/node/4660 http://www.biosharing.org/mibbi SCR_002042 MIBBI: Minimum Information for Biological and Biomedical Investigations 2026-08-12 10:48:31 1
Dendritica: Software Tools for Studying Dendritic Signaling
 
Resource Report
Resource Website
1+ mentions
Dendritica: Software Tools for Studying Dendritic Signaling (RRID:SCR_001865) simulation software, software resource, software application Dendritica is a program package for relating dendritic geometry and signal propagation. The programs are based on those used for the simulations described in the following paper: Vetter, P., Roth, A. & Husser, M. (2001). Action potential propagation in dendrites depends on dendritic morphology. Journal of Neurophysiology, 85: 926-937. Dendritica can functionally be divided into three main parts: - Interactive morphological analysis and electrophysiological simulation of single cells - Automated batch simulations across a set of morphologies using the same simulation parameters - Automated analysis of batch simulation runs Dendritica requires NEURON 4.1.1 with some modifications described in Appendix 1. It was tested for NEURON 4.1.1 on Linux and SGI IRIX. Some modifications to the Dendritica code may be necessary in order to run it on older or newer versions of NEURON. Sponsors: This work was supported by the Wellcome Trust, the European Community, the Max-Planck-Gesellschaft, the Wellcome Trust 4-year PhD Programme in Neuroscience. electrophysiological simulation, dendritic geometry, interactive, morphological, morphology, neuron, sigle cell, signal propagation Free http://www.dendrite.org/software.html SCR_001865 Dendritica 2026-08-12 10:48:29 1
Stony Brook University Medical Center: Neuropathology Primer
 
Resource Report
Resource Website
Stony Brook University Medical Center: Neuropathology Primer (RRID:SCR_001866) data or information resource, narrative resource, book This is a primer of basic neuropathology- The Central Nervous System and Skeletal Muscle. It is organized in chapters by category of disease with a separate chapter for skeletal muscle. Many of the diseases could be included in more than one chapter because of overlapping pathophysiology; in each case the disorder is included in a single section in the interest of convenience. In order to recognize pathology one must have a basic foundation in normal structure, so the first chapter is an overview of basic regional central nervous system structure and anatomy. It includes an introduction to neurohistology. Other chapters address the pathophysiology of different categories of disease and provide examples of gross and microscopic pathology when they are available. anatomy, central nervous system, disease, gross pathology, microscopic pathology, neurohistology, neuropathology, pathology, pathophysioogy, skeletal muscle, structure Free, Freely available nif-0000-10438 http://www.stonybrookmedicalcenter.org/body.cfm?id=1176 SCR_001866 Neuropathology Primer 2026-08-12 10:48:29 0
MCML and CONV
 
Resource Report
Resource Website
MCML and CONV (RRID:SCR_002419) MCML, MCML & CONV, CONV simulation software, software resource, software application MCML is a Monte Carlo simulation program for Multi-layered Turbid Media with an infinitely narrow photon beam as the light source. The simulation is specified by an input text file called, for example, sample.mci, which can be modified by any simple text editor. The output is another text file called, for example, sample.mco. (The names are arbitrary.) CONV is a convolution program which uses the MCML output file to convolve for photon beams of any size in a Gaussian or flat field shape. CONV can provide a variety of output formats (reflectance, transmission, iso-fluence contours, etc.), which are compatible with standard graphics applications. optical imaging is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Oregon Health and Science University; Oregon; USA
PMID:9421660
PMID:19256707
Free, Available for download, Freely available nlx_155791 http://www.nitrc.org/projects/mcml SCR_002419 Monte Carlo for Multi-Layered media 2026-08-12 10:48:35 0
Virtual brain
 
Resource Report
Resource Website
10+ mentions
Virtual brain (RRID:SCR_002249) tvb simulation software, software resource, software application Simulation software for modeling the entire human brain by combining structural and functional data from empirical neuroimaging data. It can generate local field potentials, EEG, MEG and fMRI BOLD data based on neural mass models. The user can also modify the model parameters to match clinical conditions from focal lesions or degenerative disorders. dti, simulation, modeling, brain is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Toronto; Ontario; Canada
James S. McDonnell Foundation PMID:23442172
PMID:23774395
Free, Freely available nlx_155567 http://www.nitrc.org/projects/tvb SCR_002249 thevirtualbrain.org, The Virtual Brain, thevirtualbrain 2026-08-12 10:48:33 45
Arvados
 
Resource Report
Resource Website
1+ mentions
Arvados (RRID:SCR_002223) arvados service resource, data repository, storage service resource Bioinformatics platform for storing, organizing, processing, and sharing genomic and other biomedical big data. Designed to make it easier for bioinformaticians to develop analyses, developers to create genomic web applications and IT administers to manage large-scale compute and storage genomic resources. Designed to run on top of cloud operating systems such as Amazon Web Services and OpenStack. Currently, there are implementations that work on AWS and Xen+Debian/Ubuntu. Functionally, Arvados has two major sets of capabilities: (a) data management and (b) compute management. mapreduce/hadoop, genomic, biomedical, data sharing, compute, data management, cloud is listed by: Debian Free, Freely available OMICS_01835 https://sources.debian.org/src/arvados/ SCR_002223 2026-08-12 10:48:33 3
Mason
 
Resource Report
Resource Website
100+ mentions
Mason (RRID:SCR_002476) simulation software, software resource, software application Collection of software tools for simulating biological sequences, including simulations of genome fragment sampling, random genomic sequences, methylation levels, and NGS reads. read simulating software, sequencing simulation, haplotype simulation is listed by: OMICtools Free, Available for download, Freely available OMICS_00252 SCR_002476 Mason2 2026-08-12 10:48:36 169
RDFaCE
 
Resource Report
Resource Website
RDFaCE (RRID:SCR_002645) RDFaCE authoring tool, software resource, software application A Semantic content editor based on TinyMCE WYSIWYG editor. RDFaCE is created as a proof of concept for WYSIWYM (What You See Is What You Mean) concept. WYSIWYM aims to enable end-users to easily annotate their content using RDFa and Microdata markups. RDFaCE employs external NLP APIs to suggest namespaces, properties, URIs and to automatically annotate content. annotation, authoring, markup, rdfa is listed by: FORCE11
has parent organization: University of Leipzig; Saxony; Germany
Free, Available for download, Freely available nlx_156074 SCR_002645 RDFa Content Editor 2026-08-12 10:48:38 0
Spanish Resting State Network
 
Resource Report
Resource Website
Spanish Resting State Network (RRID:SCR_002562) SRSN data or information resource, community building portal, portal Forum (Spanish) for sharing information and knowledge on this network, a collaboration between different research groups in Spain and national and international centres. (Foro para compartir datos y conocimiento sobre esta red. Se constituye el Spanish Resting State Network como una colaboracion entre distintos grupos de investigacion de Espa������a y centros nacionales e internacionales.) microsoft word document, magnetic resonance, nifti, pdf, spanish is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: 1000 Functional Connectomes Project
Free nlx_155968 SCR_002562 2026-08-12 10:48:37 0
Simbody(tm): SimTK Multibody Dynamics Toolset
 
Resource Report
Resource Website
1+ mentions
Simbody(tm): SimTK Multibody Dynamics Toolset (RRID:SCR_002684) simulation software, software resource, software application This project is a SimTK Core toolset providing general multibody dynamics capability, i.e., the capability to solve Newton's 2nd law F=ma in any set of coordinates. The techniques of rigid body mechanics are used to provide results in Order(n) time for any set of n coordinates. This can be used for internal coordinate modeling of molecules, or for coarse-grained models based on larger chunks. It is also useful for large-scale mechanical models, such as neuromuscular models of human gait. Simbody is provided as an open source, object-oriented C++ API and delivers high-performance, accuracy-controlled science/engineering-quality results. Binaries of this software are bundled with other SimTK Core modules. articulated body, coarse-grained molecule modeling, constrained motion, internal coordinates, mechanical simulation, mechanics, molecular dynamics, multibody dynamics, rigid body, simtk core, skeletal mechanics, torsion coordinates is used by: CPODES numerical integrator
is related to: Simtk.org
PMID:25866705 Free, Available for download, Freely available nif-0000-23309 SCR_002684 Simbody 2026-08-12 10:48:39 1
ESTHER
 
Resource Report
Resource Website
100+ mentions
ESTHER (RRID:SCR_002621) ESTHER data or information resource, database Database and tools for analysis of protein and nucleic acid sequences belonging to superfamily of alpha/beta hydrolases homologous to cholinesterases. Covers multiple species, including human, mouse caenorhabditis and drosophila., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. alpha hydrolase, beta hydrolase, cholinesterase, protein, protein superfamily, blast, gene, protein binding, protein-protein interaction, nucleotide, nucleotide sequence, enzyme, genetics, genome, genomics, mutation, disease, gene expression, peptide, chromosome is listed by: re3data.org
is related to: UniProtKB
is related to: AceDB
has parent organization: INRA - French National Institute for Agricultural Research; Paris; France
PMID:23193256 Free, Available for download, Freely available nif-0000-30526, SCR_008479, nif-0000-02817, r3d100010542 https://doi.org/10.17616/R33K77 SCR_002621 ESTerases and alpha/beta-Hydrolase Enzymes and Relatives, ESTHER Database, ESTerases and alpha / beta-hydrolase Enzymes and Relatives 2026-08-12 10:48:38 134
pIRS
 
Resource Report
Resource Website
50+ mentions
pIRS (RRID:SCR_002519) simulation software, software resource, software application Software for de novo data simulation. It uses empirical distribution to reproduce Illumina pair-end reads with real distribution of substitution sequencing errors, quality values and GC%-depth bias. de novo data simulation, empirical distribution, illumina pair-end read, substitution sequencing error, gc depth bias is listed by: OMICtools PMID:22508794 Free, Available for download, Freely available OMICS_00254 SCR_002519 pIRS (profile based Illumina pair-end Reads Simulator), profile based Illumina pair-end Reads Simulator 2026-08-12 10:48:36 74
NEURON
 
Resource Report
Resource Website
100+ mentions
NEURON (RRID:SCR_017449) simulation software, software resource, software application Software for computational neurophysiology. Simulation environment is used for building and using computational models of neurons and networks of neurons. NEURON Users Group can participate in collaborative development of documentation, tutorials, and software. Computational, neurophysiology, model, neuron, network, building, BRAIN Initiative is recommended by: BRAIN Initiative
has parent organization: Yale University; Connecticut; USA
NIBIB EB022903 Free, Available for download, Freely available https://github.com/neuronsimulator/nrn SCR_017449 2026-08-12 10:51:49 244

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