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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
ComplexHeatmap
 
Resource Report
Resource Website
1000+ mentions
ComplexHeatmap (RRID:SCR_017270) data processing software, software application, data visualization software, data analysis software, software resource Software package to arrange multiple heatmaps and support various annotation graphics. Used to visualize associations between different sources of data sets and to reveal potential patterns. arrange, multiple, heatmap, visualize, data, pattern, genomic, dataset, bio.tools is listed by: Debian
is listed by: bio.tools
German Cancer Research Center-Heidelberg Center for Personalized Oncology ;
BMBF
PMID:27207943 Free, Available for download, Freely available biotools:complexheatmap https://github.com/jokergoo/ComplexHeatmap, https://bio.tools/complexheatmap SCR_017270 2026-08-05 10:46:45 3266
SWISS-MODEL
 
Resource Report
Resource Website
1000+ mentions
SWISS-MODEL (RRID:SCR_018123) data or information resource, data access protocol, software resource, service resource, web service Software tool as fully automated protein structure homology modeling server, accessible via ExPASy web server, or from program DeepView Swiss Pdb-Viewer. Structural bioinformatics web-server dedicated to homology modeling of 3D protein structures. Used to make protein modelling accessible to all biochemists and molecular biologists. 3D protein structure, homology modeling server, protein modeling, structural bioinformatics, automated comparative modeling, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: ExPASy Bioinformatics Resource Portal
is related to: Swiss-PdbViewerDeepViewv4.0
has parent organization: University of Basel; Basel; Switzerland
provides: SWISS-MODEL Repository
PMID:12824332 Free, Freely available biotools:swiss-model_workspace, biotools:swiss_model https://bio.tools/swiss_model, https://bio.tools/swiss-model_workspace SCR_018123 2026-08-05 10:46:56 2796
SIGNOR
 
Resource Report
Resource Website
10+ mentions
SIGNOR (RRID:SCR_018485) data or information resource, data repository, database, storage service resource, service resource Software application to organize and store in structured format signaling information published in scientific literature. Information is stored as binary causative relationships between biological entities and can be represented graphically as activity flow. Each relationship is linked to literature reporting experimental evidence. Each node is annotated with chemical inhibitors that modulate its activity. Signaling information is mapped to human proteome. SIGNOR 2.0 stores manually annotated causal relationships between proteins and other biologically relevant entities including chemicals, phenotypes, complexes, etc with compliance to FAIR data principles. Signal transduction data, signaling information, published data collection, activity flow, chemical inhibitor, human proteome, manually annotated data, protein, protein relationship, FAIR data, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: REDIportal
Italian Association for Cancer Research ;
ELIXIR-IIB ;
Italian Node of the European ELIXIR infrastructure ;
EMBL-EBI
PMID:31665520 Free, Available for download, Freely available biotools:signor https://bio.tools/signor SCR_018485 SIGnaling Network Open Resource, SIGNOR 2.0 2026-08-05 10:47:01 40
FaceSync project
 
Resource Report
Resource Website
FaceSync project (RRID:SCR_021393) data or information resource, project portal, instrument resource, portal Project related to emotions and facial expressions. Includes open source guide to building affordable head mount for camera to maintain high temporal and spatial resolution of face throughout duration of experiment. Device is paired with FaceSync, Python toolbox which automatically synchronizes recorded facial expressions to videos and events such as social interactions. Automatically synchronize videos, manually align audio, plot facial landmark movements, graph data, head mounted camera setup, 3D blueprints, recording facial expressions, OpenBehavior, Bio.Tools, Instrument is listed by: OpenBehavior
is related to: FaceSync
PMID:32185017 Free, Freely available SCR_021393 2026-08-05 10:47:25 0
EvidenceFinder
 
Resource Report
Resource Website
1+ mentions
EvidenceFinder (RRID:SCR_013764) software resource, web application A web application to assist in the identification of articles and research related to literature search terms. The search covers full text articles in the Europe PMC repository. Relevant papers are suggested to users based on the scientific term searched and the selection of questions, generated by the application, relevant to term searched. web application, software resource, literature search, bio.tools is used by: Europe PubMed Central
is listed by: Connected Researchers
is listed by: Debian
is listed by: bio.tools
is related to: Connected Researchers
is related to: Europe PubMed Central
has parent organization: Europe PubMed Central
Wellcome Trust 098231 DOI:10.1093/nar/gku1061 Free, Public biotools:evidence_finder https://bio.tools/evidence_finder SCR_013764 2026-08-05 10:46:03 3
Mspire-Simulator
 
Resource Report
Resource Website
1+ mentions
Mspire-Simulator (RRID:SCR_001431) software application, simulation software, standalone software, software resource A free, open-source shotgun proteomic simulator that goes beyond previous simulation attempts by generating LC-MS features with realistic m/z and intensity variance along with other noise components. standalone software, shotgun, proteomic, simulation software, bio.tools uses: mzML
is listed by: OMICtools
is listed by: GitHub
is listed by: bio.tools
is listed by: Debian
has parent organization: Brigham Young University; Utah; USA
PMID:24090032 Free, Freely Available biotools:mspire-simulator, OMICS_03359 https://bio.tools/mspire-simulator SCR_001431 2026-08-05 10:43:22 1
IMG System
 
Resource Report
Resource Website
100+ mentions
IMG System (RRID:SCR_002965) IMG, IMG/M data or information resource, portal Resource for analysis and annotation of genome and metagenome datasets in comprehensive comparative context. IMG provides users with tools for analyzing publicly available genome datasets and metagenome datasets. microbiome, microbial genetics, genome and metagenome datasets analysis, genome and metagenome datasets, genome, metagenomics, bio.tools, FASEB list is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: Human Microbiome Project
has parent organization: DOE Joint Genome Institute
PMID:17932063
PMID:22086953
Free, Freely available nif-0000-03010, OMICS_01478, SCR_014605, biotools:img_m http://img.jgi.doe.gov/m, https://bio.tools/img_m SCR_002965 Integrated Microbial Genomes System 2026-08-05 10:43:44 199
EchoBASE
 
Resource Report
Resource Website
1+ mentions
EchoBASE (RRID:SCR_002430) EchoBASE data or information resource, database A database that curates new experimental and bioinformatic information about the genes and gene products of the model bacterium Escherichia coli K-12 strain MG1655. It has been created to integrate information from post-genomic experiments into a single resource with the aim of providing functional predictions for the 1500 or so gene products for which we have no knowledge of their physiological function. While EchoBASE provides a basic annotation of the genome, taken from other databases, its novelty is in the curation of post-genomic experiments and their linkage to genes of unknown function. Experiments published on E. coli are curated to one of two levels. Papers dealing with the determination of function of a single gene are briefly described, while larger dataset are actually included in the database and can be searched and manipulated. This includes data for proteomics studies, protein-protein interaction studies, microarray data, functional genomic approaches (looking at multiple deletion strains for novel phenotypes) and a wide range of predictions that come out of in silico bioinformatic approaches. The aim of the database is to provide hypothesis for the functions of uncharacterized gene products that may be used by the E. coli research community to further our knowledge of this model bacterium. gene, bio.tools is listed by: bio.tools
is listed by: Debian
GlaxoSmithKline ;
BBSRC
PMID:15608209 nif-0000-02781, biotools:echobase, r3d100011646 https://bio.tools/echobase, https://doi.org/10.17616/R38W6H SCR_002430 EchoBASE: an integrated post-genomic database for Escherichia coli 2026-08-05 10:43:37 6
Autophagy Database
 
Resource Report
Resource Website
10+ mentions
Autophagy Database (RRID:SCR_002671) Autophagy DB, AutophagyDB data or information resource, database Database that provides basic, up-to-date information on relevant literature, and a list of autophagy-related proteins and their homologs in eukaryotes. autophagy, protein, homolog, ortholog, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Tokyo; Tokyo; Japan
Japanese Ministry of Education Culture Sports Science and Technology MEXT PMID:20972215 Free, Available for download, Freely available OMICS_03306, biotools:the_autophagy_database, r3d100012565 https://bio.tools/the_autophagy_database, https://doi.org/10.17616/R3J786 SCR_002671 2026-08-05 10:43:39 17
DOMINE: Database of Protein Interactions
 
Resource Report
Resource Website
1+ mentions
DOMINE: Database of Protein Interactions (RRID:SCR_002399) DOMINE data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 13,2026. Database of known and predicted protein domain (domain-domain) interactions containing interactions inferred from PDB entries, and those that are predicted by 8 different computational approaches using Pfam domain definitions. DOMINE contains a total of 26,219 domain-domain interactions (among 5,410 domains) out of which 6,634 are inferred from PDB entries, and 21,620 are predicted by at least one computational approach. Of the 21,620 computational predictions, 2,989 interactions are high-confidence predictions (HCPs), 2,537 interactions are medium-confidence predictions (MCPs), and the remaining 16,094 are low-confidence predictions (LCPs). (May 2014) domain-domain interaction, prediction, protein domain, interaction, protein domain interaction, protein, domain, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
is related to: Pfam
has parent organization: University of Texas at Dallas; Texas; USA
PMID:21113022
PMID:17913741
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01906, nif-0000-02758, biotools:domine https://bio.tools/domine SCR_002399 Database of Protein Domain Interactions 2026-08-05 10:43:38 1
VIPERdb
 
Resource Report
Resource Website
50+ mentions
VIPERdb (RRID:SCR_002853) data or information resource, database Database for icosahedral virus capsid structures. The emphasis of the resource is on providing data from structural and computational analyses on these systems, as well as high quality renderings for visual exploration. In addition, all virus capsids are placed in a single icosahedral orientation convention, facilitating comparison between different structures. The web site includes powerful search utilities , links to other relevant databases, background information on virus capsid structure, and useful database interface tools. It is an information source for the analysis of high resolution virus structures. VIPERdb is a one-stop site dedicated to helping users around the world examine the many icosahedral virus structures contained within the Protein Data Bank (PDB) by providing them with an easy to use database containing current data and a variety of analytical tools. Sponsors: VIPERdb is funded by the NIH., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. exploration, analysis, capsid, computational, convention, database, icosahedral, structural, structure, system, virus, visual, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: Scripps Research Institute
PMID:33313778
PMID:30265627
Free, Freely available nif-0000-25311, r3d100012362, nif-0000-03630, biotools:viperdb, SCR_007970 https://bio.tools/viperdb, https://doi.org/10.17616/R3HT0Q SCR_002853 Virus Particle ExploreR 2026-08-05 10:43:42 59
Human Gene Connectome Server
 
Resource Report
Resource Website
1+ mentions
Human Gene Connectome Server (RRID:SCR_002627) HGCS data analysis service, production service resource, service resource, analysis service resource An interactive web server that enables researchers to prioritize any list of genes by their biological proximity to defined core genes (i.e. genes that are known to be associated with the phenotype), and to predict novel gene pathways. gene, disease, phenotype, genome, connectome, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Human Gene Connectome
PMID:23509278 Free nlx_156049, biotools:hgcs https://bio.tools/hgcs SCR_002627 2026-08-05 10:43:39 5
Nucleic Acid Database
 
Resource Report
Resource Website
10+ mentions
Nucleic Acid Database (RRID:SCR_003255) NDB data or information resource, database A database of three-dimensional structural information about nucleic acids and their complexes. In addition to primary data, it contains derived geometric data, classifications of structures and motifs, standards for describing nucleic acid features, as well as tools and software for the analysis of nucleic acids. A variety of search capabilities are available, as are many different types of reports. NDB maintains the macromolecular Crystallographic Information File (mmCIF). nucleic acid, dna, nucleopeptide, nucleoprotein, nucleotide, rna, transfection, sequence, structure, function, bio.tools, FASEB list is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: MINAS - Metal Ions in Nucleic AcidS
is related to: Biological Magnetic Resonance Data Bank (BMRB)
is related to: Jenalib: Jena Library of Biological Macromolecules
has parent organization: Rutgers University; New Jersey; USA
NSF ;
DOE ;
NIH
PMID:24185695
PMID:1384741
Free, Available for download, Freely available nif-0000-03184, biotools:ndb, r3d100010415 https://bio.tools/ndb, https://doi.org/10.17616/R3531R SCR_003255 2026-08-05 10:43:48 36
RefSeq
 
Resource Report
Resource Website
10000+ mentions
RefSeq (RRID:SCR_003496) data or information resource, database Collection of curated, non-redundant genomic DNA, transcript RNA, and protein sequences produced by NCBI. Provides a reference for genome annotation, gene identification and characterization, mutation and polymorphism analysis, expression studies, and comparative analyses. Accessed through the Nucleotide and Protein databases. reference sequence, transcript, protein, dna, rna, plasmid, organelle, virus, genome, nucleic acid, ortholog, paralog, haplotype, nucleotide sequence, gene expression, blast, gold standard, bio.tools is listed by: OMICtools
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: BeetleBase
is related to: EcoGene
is related to: INSDC
is related to: HFV Database
is related to: RefSeqGene
is related to: NCBI Protein Database
is related to: RefSeqGene
is related to: UniParc at the EBI
is related to: NCBI Nucleotide
is related to: UniParc
is related to: ProRepeat
is related to: NCBI Virus
is related to: Codon and Codon-Pair Usage Tables
is related to: RefSeq non-redundant proteins
has parent organization: NCBI
PMID:24316578
PMID:24259432
PMID:22121212
PMID:18927115
PMID:17130148
PMID:15608248
Free, Available for download, Freely available SCR_016579, nif-0000-03397, OMICS_01659, biotools:refseq, r3d100011306 ftp://ftp.ncbi.nlm.nih.gov/refseq, https://bio.tools/refseq, https://doi.org/10.17616/R3HP70 SCR_003496 RefSeq, , Reference Sequence Database, Reference Sequence, Reference Sequences, NCBI 2026-08-05 10:43:51 18049
MutDB
 
Resource Report
Resource Website
10+ mentions
MutDB (RRID:SCR_003251) data or information resource, database Database with annotations for human variation data with protein structural information and other functionally relevant information, if available. The mutations are organized by gene. web database, annotation database, human genome, human protein, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Buck Institute; California; USA
PMID:15980479 Free, Freely available biotools:mutdb, nif-0000-03173 https://bio.tools/mutdb SCR_003251 2026-08-05 10:43:48 10
Proteome Analyst Specialized Subcellular Localization Server
 
Resource Report
Resource Website
1+ mentions
Proteome Analyst Specialized Subcellular Localization Server (RRID:SCR_003143) PA-SUB data analysis service, production service resource, service resource, analysis service resource Web server specialized to predict the subcellular localization of proteins using established machine learning techniques. subcellular localization, protein, machine learning, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Alberta; Alberta; Canada
PMID:14990451 Free, Available for download, Freely available biotools:pa-sub, OMICS_01631 https://psort.org/#:~:text=Proteome%20Analyst's%20Subcellular%20Localization%20Server, proteins%20to%20many%20localization%20sites. SCR_003143 2026-08-05 10:43:46 1
PolymiRTS
 
Resource Report
Resource Website
100+ mentions
PolymiRTS (RRID:SCR_003389) PolymiRTS data or information resource, database Database of naturally occurring DNA variations in microRNA (miRNA) seed regions and miRNA target sites. MicroRNAs pair to the transcripts of protein-coding genes and cause translational repression or mRNA destabilization. SNPs and INDELs in miRNAs and their target sites may affect miRNA-mRNA interaction, and hence affect miRNA-mediated gene repression. The PolymiRTS database was created by scanning 3'UTRs of mRNAs in human and mouse for SNPs and INDELs in miRNA target sites. Then, the potential downstream effects of these polymorphisms on gene expression and higher-order phenotypes are identified. Specifically, genes containing PolymiRTSs, cis-acting expression QTLs, and physiological QTLs in mouse and the results of genome-wide association studies (GWAS) of human traits and diseases are linked in the database. The PolymiRTS database also includes polymorphisms in target sites that have been supported by a variety of experimental methods and polymorphisms in miRNA seed regions. polymorphism, microrna, human, disease, trait, snp, indel, pathway, genetic variant, gene expression, phenotype, chromosome, chromosome location, bio.tools, FASEB list is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Tennessee Health Science Center; Tennessee; USA
PhRMA Foundation ;
UT Center for Integrative and Translational Genomics ;
NICHD HD052472;
NIAAA AA014425;
NIDA DA021131;
NINR NR009270;
NIAID AI081050;
NIAID AI019782;
American Heart Association 0830134N;
United States Department of Defense W81XHW-05-01-0227
PMID:24163105
PMID:22080514
Free, Available for download, Freely available nif-0000-03324, biotools:polymirts, OMICS_00391 https://bio.tools/polymirts http://compbio.utmem.edu/miRSNP/ SCR_003389 Polymorphism in microRNA Target Site, PolymiRTS Database, Polymorphism in microRNAs and their TargetSites 2026-08-05 10:43:50 149
FastSNP
 
Resource Report
Resource Website
50+ mentions
FastSNP (RRID:SCR_003140) data analysis service, production service resource, service resource, analysis service resource THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 9, 2016. A web server that allows users to efficiently identify and prioritize high-risk SNPs according to their phenotypic risks and putative functional effects. A unique feature is that the functional effect information used for SNP prioritization is always up-to-date, because FASTSNP extracts the information from 11 external web servers at query time using a team of web wrapper agents. Moreover, FASTSNP is extendable by deploying more Web wrapper agents. FASTSNP provides three options for users to submit requests. If users already have some candidate SNPs on a candidate gene, they may use Query by Candidate Gene to select the specific SNPs on the gene to perform prioritization. If users have a specified SNP or a list of SNP rsid's needs to be prioritized, they can use Query by SNP option and upload the SNP list in an Excel-format file. Finally, if users have a novel SNP sequence, FASTSNP provides Novel SNP analysis. FASTSNP will generate a SNP Function Report for each SNP. Users can export SNP data to an excel file for further genotyping processes. Other features of FASTSNP include SNP quality checking and haplotype LD information. single nucleotide polymorphism, function, phenotype, transcript, prioritize, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Academia Sinica; Taipei; Taiwan
National Research Program in Genomic Medicine ;
National Science Council Taiwan NSC93-3112-B-001-008-Y;
National Science Council Taiwan NSC93-3112-B-001-018-Y
PMID:16845089 Free, Freely available biotools:fastsnp, OMICS_00173, nif-0000-30566 https://bio.tools/fastsnp http://fastsnp.ibms.sinica.edu.tw/pages/input_CandidateGeneSearch.jsp SCR_003140 FastSNP: A Functional Analysis and Selection Tool for SNP in Large Scale Association Study, Function Analysis and Selection Tool for Single Nucleotide Polymorphisms, A Functional Analysis and Selection Tool for SNP in Large Scale Association Study 2026-08-05 10:43:46 62
PHI-base
 
Resource Report
Resource Website
100+ mentions
PHI-base (RRID:SCR_003331) PHI-base data or information resource, database Database that catalogs experimentally verified pathogenicity, virulence and effector genes from fungal, Oomycete and bacterial pathogens, which infect animal, plant, fungal and insect hosts. It is an invaluable resource in the discovery of genes in medically and agronomically important pathogens, which may be potential targets for chemical intervention. In collaboration with the FRAC team, it also includes antifungal compounds and their target genes. Each entry is curated by domain experts and is supported by strong experimental evidence (gene disruption experiments, STM etc), as well as literature references in which the original experiments are described. Each gene is presented with its nucleotide and deduced amino acid sequence, as well as a detailed description of the predicted protein's function during the host infection process. To facilitate data interoperability, genes have been annotated using controlled vocabularies and links to external sources (Gene Ontology terms, EC Numbers, NCBI taxonomy, EMBL, PubMed and FRAC). gene expression, pathogenic bacteria, virulence, infection, target site, gene, pathogen-host interaction, interaction, phenotype, pathogen, disease, host, anti-infective, nucleotide sequence, amino acid sequence, bio.tools, FASEB list is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
BBSRC BB/1000488/1 PMID:17942425
PMID:17153929
PMID:16381911
Free, Freely available nif-0000-03276, r3d100011301, biotools:phi-base https://bio.tools/phi-base, https://doi.org/10.17616/R35D1V http://www4.rothamsted.bbsrc.ac.uk/phibase/ SCR_003331 Pathogen Host Interaction base, Pathogen Host Interaction, Pathogen Host Interaction-Base 2026-08-05 10:43:49 198
T-profiler
 
Resource Report
Resource Website
10+ mentions
T-profiler (RRID:SCR_003452) T-profiler data analysis service, production service resource, service resource, analysis service resource One of the key challenges in the analysis of gene expression data is how to relate the expression level of individual genes to the underlying transcriptional programs and cellular state. The T-profiler tool hosted on this website uses the t-test to score changes in the average activity of pre-defined groups of genes. The gene groups are defined based on Gene Ontology categorization, ChIP-chip experiments, upstream matches to a consensus transcription factor binding motif, and location on the same chromosome, respectively. If desired, an iterative procedure can be used to select a single, optimal representative from sets of overlapping gene groups. A jack-knife procedure is used to make calculations more robust against outliers. T-profiler makes it possible to interpret microarray data in a way that is both intuitive and statistically rigorous, without the need to combine experiments or choose parameters. Currently, gene expression data from Saccharomyces cerevisiae and Candida albicans are supported. Users can submit their microarray data for analysis by clicking on one of the two organism-specific tabs above. Platform: Online tool expression, gene, binding, cellular, transcriptional, gene expression, microarray, gene ontology, transcription factor, binding motif, chip-chip, chip, motif, t-test, statistical analysis, transcriptome, bio.tools is listed by: Biositemaps
is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: Columbia University; New York; USA
has parent organization: University of Amsterdam; Amsterdam; Netherlands
Netherlands Foundation for Technical Research APB.5504;
NHGRI R01HG003008
PMID:15980543 Free for academic use nif-0000-33354, biotools:t-profiler https://bio.tools/t-profiler SCR_003452 T-profiler: Scoring the Activity of Pre-defined Groups of Genes Using Gene Expression Data 2026-08-05 10:43:51 11

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