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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
CoIN
 
Resource Report
Resource Website
100+ mentions
CoIN (RRID:SCR_005332) CoIN service resource A web-based system that assess articles according to their term correlations among sentences. It employs the co-occurrence relations and their network centralities to evaluate the influence of biomedical terms from Comparative Toxicogenomics Database (CTD)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, disease, chemical, biomedical, association, document triage, database, FASEB list is listed by: OMICtools
has parent organization: National Cheng Kung University; Tainan; Taiwan
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01177 SCR_005332 Co-occurrence Interaction Nexus, CoIN: A network exploration for document triage, CoIN: Co-occurrence Interaction Nexus 2026-08-01 12:02:58 138
Manatee
 
Resource Report
Resource Website
50+ mentions
Manatee (RRID:SCR_005685) Manatee software resource Manatee is a web-based gene evaluation and genome annotation tool; Manatee can store and view annotation for prokaryotic and eukaryotic genomes. The Manatee interface allows biologists to quickly identify genes and make high quality functional assignments, such as GO classifications, using search data, paralogous families, and annotation suggestions generated from automated analysis. Manatee can be downloaded and installed to run under the CGI area of a web server, such as Apache. Platform: Online tool, Linux compatible, Solaris gene, genome, annotation, ontology or annotation browser, ontology or annotation editor is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: J. Craig Venter Institute
has parent organization: University of Maryland School of Medicine; Maryland; USA
has parent organization: SourceForge
Open unspecified license - Free for academic use nlx_149128 SCR_005685 2026-08-01 12:02:56 64
tranSMART
 
Resource Report
Resource Website
10+ mentions
tranSMART (RRID:SCR_005586) tranSMART software resource tranSMART is a knowledge management platform that enables scientists to develop and refine research hypotheses by investigating correlations between genetic and phenotypic data, and assessing their analytical results in the context of published literature and other work. tranSMART is licensed through GPL 3. The integration, normalization, and alignment of data in tranSMART permits users to explore data very efficiently to formulate new research strategies. Some of tranSMART''s specific applications include: * Revalidating previous hypotheses * Testing and refining novel hypotheses * Conducting cross-study meta-analysis * Searching across multiple data sources to find associations of concepts, such as a gene''s involvement in biological processes or experimental results * Comparing biological processes and pathways among multiple data sets from related diseases or even across multiple therapeutic areas Data Repository The tranSMART Data Repository combines a data warehouse with access to federated sources of open and commercial databases. tranSMART accommodates: * Phenotypic data, such as demographics, clinical observations, clinical trial outcomes, and adverse events * High content biomarker data, such as gene expression, genotyping, pharmacokinetic and pharmaco-dynamics markers, metabolomics data, and proteomics data * Unstructured text-data, such as published journal articles, conference abstracts and proceedings, and internal studies and white papers * Reference data from sources such as MeSH, UMLS, Entrez, GeneGo, Ingenuity, etc. * Metadata providing context about datasets, allowing users to assess the relevance of results delivered by tranSMART Data in tranSMART is aligned to allow identification and analysis of associations between phenotypic and biomarker data, and it is normalized to conform with CDISC and other standards to facilitate search and analysis across different data sources. tranSMART also enables investigators to search published literature and other text sources to evaluate their analysis in the context of the broader universe of reported research. External data can also be integrated into the tranSMART data repository, either from open data projects like GEO, EBI Array Express, GCOD, or GO, or from commercially available data sources. Making data accessible in tranSMART enables organizations to leverage investments in manual curation, development costs of automated ETL tools, or commercial subscription fees across multiple research groups. Dataset Explorer tranSMART''s Dataset Explorer provides flexible, powerful search and analysis capabilities. The core of the Dataset Explorer integrates and extends the open source i2b2 application, Lucene text indexing, and GenePattern analytical tools. Connections to other open source and commercial analytical tools such as Galaxy, Integrative Genomics Viewer, Plink, Pathway Studio, GeneGo, Spotfire, R, and SAS can be established to expand tranSMART''s capabilities. tranSMART''s design allows organizations flexibility in selecting analytical tools accessible through the Dataset Explorer, and provides file export capabilities to enable researchers to use tools not accessible in the tranSMART portal. source code, genetic, phenotype, gene, data storage repository, data analysis service is used by: eTRIKS
is used by: RanchoBiosciences
nlx_146211 http://www.transmartproject.org/ SCR_005586 2026-08-01 12:03:00 13
JEPETTO
 
Resource Report
Resource Website
10+ mentions
JEPETTO (RRID:SCR_005909) JEPETTO software resource A Cytoscape plugin that performs integrated gene set analysis using information from interaction, pathways and processes databases. The plugin integrates information from three separate web servers specializing in enrichment analysis, pathways expansion and topological matching. It uses the TopoGSA server to identify topological analogies between the user selected gene set and the known pathways and processes. TopoGSA finds the most similar biological mechanism using the topological features of the interaction network of a user selected gene set. It is also able to suggest genes related to the query gene set using two pathway analysis servers EnrichNet and PathExpand. Both these servers are using a different topological matching algorithms that extends the query gene set with genes from the pathway databases. This integration substantially simplifies the analysis of user gene sets and the interpretation of the results. gene set enrichment analysis, topological analysis, interaction network, java, enrichment analysis, functional analysis, gene prioritization, integrated analysis, network analysis, interaction, pathway, process, topology, gene is listed by: OMICtools
has parent organization: Cytoscape
has parent organization: Newcastle University; Newcastle upon Tyne; United Kingdom
PMID:24363376 GNU General Public License OMICS_02247 SCR_005909 Java Enrichment of Pathways Extended To Topology 2026-08-01 12:03:00 15
Cascade
 
Resource Report
Resource Website
50+ mentions
Cascade (RRID:SCR_005861) Cascade software resource R software package to study, predict and simulate the diffusion of a signal through a temporal gene network. It predicts changes in gene expressions after a biological perturbation in the network and provides graphical outputs that allow monitoring the spread of a signal through the network., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. r, windows, gene expression, perturbation, network, diffusion, signal, temporal gene network, gene regulatory network, gene, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Strasbourg; Strasbourg; France
PMID:24307703 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02249, biotools:cascade http://www-math.u-strasbg.fr/genpred/spip.php?rubrique4, https://bio.tools/cascade SCR_005861 2026-08-01 12:03:00 92
BiNGO: A Biological Networks Gene Ontology tool
 
Resource Report
Resource Website
500+ mentions
BiNGO: A Biological Networks Gene Ontology tool (RRID:SCR_005736) BiNGO software resource The Biological Networks Gene Ontology tool (BiNGO) is an open-source Java tool to determine which Gene Ontology (GO) terms are significantly overrepresented in a set of genes. BiNGO can be used either on a list of genes, pasted as text, or interactively on subgraphs of biological networks visualized in Cytoscape. BiNGO maps the predominant functional themes of the tested gene set on the GO hierarchy, and takes advantage of Cytoscape''''s versatile visualization environment to produce an intuitive and customizable visual representation of the results. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible gene ontology, gene, ontology, statistical analysis, term enrichment, biological network, plugin, bio.tools is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Cytoscape
has parent organization: Ghent University; Ghent; Belgium
PMID:15972284 Open unspecified license - Free for academic use nlx_149196, biotools:bingo https://bio.tools/bingo SCR_005736 Biological Networks Gene Ontology 2026-08-01 12:02:58 790
DynGO
 
Resource Report
Resource Website
1+ mentions
DynGO (RRID:SCR_007009) DynGO software resource DynGO is a client-server application that provides several advanced functionalities in addition to the standard browsing capability. DynGO allows users to conduct batch retrieval of GO annotations for a list of genes and gene products, and semantic retrieval of genes and gene products sharing similar GO annotations (which requires more disk and memory to handle the semantic retrieval). The result are shown in an association tree organized according to GO hierarchies and supported with many dynamic display options such as sorting tree nodes or changing orientation of the tree. For GO curators and frequent GO users, DynGO provides fast and convenient access to GO annotation data. DynGO is generally applicable to any data set where the records are annotated with GO terms, as illustrated by two examples. Requirements: Java Platform: Windows compatible, Linux compatible, Unix compatible gene, annotation, browser, ontology or annotation browser is listed by: Gene Ontology Tools
is related to: Gene Ontology
NSF IIS-0430743 PMID:16091147 Free for academic use nlx_149118 http://gauss.dbb.georgetown.edu/liblab SCR_007009 DynGO: a tool for visualizing and mining of Gene Ontology and its associations 2026-08-01 12:03:16 6
Tk-GO
 
Resource Report
Resource Website
Tk-GO (RRID:SCR_008855) TkGO software resource Tk-GO is a GUI wrapping the basic functions of the GO AppHandle library from BDGP. GO terms are presented in an explorer-like browser, and behavior can be configured by altering Perl scripts. All available documentation is included in the download. Tk-GO uses the GO database (connects directly to the BDGP database by default) but is user-configurable. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible browser, gene, ontology or annotation browser is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Illumina
MIT License - Free for academic use nlx_149133 SCR_008855 2026-08-01 12:03:38 0
Spotfire
 
Resource Report
Resource Website
100+ mentions
Spotfire (RRID:SCR_008858) Spotfire software resource The Spotfire Gene Ontology Advantage Application integrates GO annotations with gene expression analysis in Spotfire DecisionSite for Functional Genomics. Researchers can select a subset of genes in DecisionSite visualizations and display their distribution in the Gene Ontology hierarchy. Similarly, selection of any process, function or cellular location in the Gene Ontology hierarchy automatically marks the corresponding genes in DecisionSite visualizations. Platform: Windows compatible analysis, predictive analytics, big data, visualization, gene ontology, annotation, gene expression, functional genomics, gene, function, cellular location, statistical analysis, genomics is listed by: Gene Ontology Tools
is listed by: Metabolomics Workbench
is related to: Gene Ontology
Commercial license. Spotfire is available for purchase (individual license / enterprise use) / Free trial. nlx_149169 SCR_008858 Tibco Spotfire, Spotfire Inc., Spotfire Gene Ontology Advantage Application, Spotfire - TIBCO Software 2026-08-01 12:03:39 474
caGWAS
 
Resource Report
Resource Website
caGWAS (RRID:SCR_009617) caGWAS software resource Too that allows researchers to integrate, query, report, and analyze significant associations between genetic variations and disease, drug response or other clinical outcomes. SNP array technologies make it possible to genotype hundreds of thousands of single nucleotide polymorphisms (SNPs) simultaneously, enabling whole genome association studies. Within the Clinical Genomic Object Model (CGOM), the caIntegrator team created a domain model for Whole Genome Association Study Analysis. CGOM-caGWAS is a A semantically annotated domain model that captures associations between Study, Study Participant, Disease, SNP Association Analysis, SNP Population Frequency and SNP annotations. caGWAS APIs and web portal provide: * a semantically annotated domain model, database schema with sample data, seasoned middleware, APIs, and web portal for GWAS data; * platform and disease agnostic CGOM-caGWAS model and associated APIs; * the opportunity for developers to customize the look and feel of their GWAS portal; * a foundation of open source technologies; * a well-tested and performance-enhanced platform, as the same software is being used to house the CGEMS data portal; * accelerated analysis of results from various biomedical studies; and * a single application through which researchers and bioinformaticians can access and analyze clinical and experimental data from a variety of data types, as caGWAS objects are part of the CGOM, which includes microarray, genomic, immunohistochemistry, imaging, and clinical data. application, computational neuroscience, genetic association, genomic analysis, imaging genomics, java, snp, gene, software, web environment, microarray, genomic, immunohistochemistry, imaging, clinical is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: National Cancer Institute
BSD License nlx_155841 http://www.nitrc.org/projects/cagwas SCR_009617 caGWAS (Cancer Genome-Wide Association Studies), Cancer Genome-Wide Association Studies, CGOM-caGWAS 2026-08-01 12:04:03 0
Illumina
 
Resource Report
Resource Website
1000+ mentions
Illumina (RRID:SCR_010233) Illumina, Inc. commercial organization American company incorporated that develops, manufactures and markets integrated systems for the analysis of genetic variation and biological function. Provides a line of products and services that serve the sequencing, genotyping and gene expression and proteomics markets. Its headquarters are located in San Diego, California. Commercial, organization, develope, manufacture, system, analysis, genetic, sequencing, genotyping, gene, expression, proteomic is related to: fermi-lite
is related to: Illumina: NextSeq 2000 system
is parent organization of: Strelka2
is parent organization of: Tk-GO
is parent organization of: BaseSpace
is parent organization of: Illumina: iSeq 100 Sequencing System
nlx_156846, grid.185669.5, Wikidata: Q2068984, ISNI: 0000 0004 0507 3954 https://ror.org/05k34t975 SCR_010233 Inc., Illumina 2026-08-01 12:03:47 2340
rbsurv
 
Resource Report
Resource Website
1+ mentions
rbsurv (RRID:SCR_001175) rbsurv software resource Software package that selects genes associated with survival. microarray, gene, survival, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available biotools:rbsurv, BioTools:rbsurv, OMICS_02088 https://bio.tools/rbsurv, https://bio.tools/rbsurv, https://bio.tools/rbsurv SCR_001175 rbsurv - Robust likelihood-based survival modeling with microarray data 2026-08-01 12:01:24 1
Sherlock
 
Resource Report
Resource Website
50+ mentions
Sherlock (RRID:SCR_001628) Sherlock data or information resource, service resource Service to discover disease genes in GWAS using eQTL signature matching by simply submitting your list of GWAS associations (SNPs and p-values). It is important to upload all SNPs in your association study, not just the top hits. Sherlock may be able to group multiple lower-confidence SNPs to discover functionally-important genes. genome-wide association study, expression quantitative trait locus, disease gene, snp, gene expression, gene, disease, association, p-value, cis, trans, genetic variation, mapping, phenotype, FASEB list has parent organization: University of California at San Francisco; California; USA NIGMS R01GM070808;
NIGMS U19GM61390;
NIGMS P50 GM081879
PMID:23643380 Free, Freely available nlx_153895 SCR_001628 2026-08-01 12:01:57 86
rSeqDiff
 
Resource Report
Resource Website
rSeqDiff (RRID:SCR_001683) rSeqDiff software resource An R package that can detect differential gene and isoform expressions from RNA-seq data of multiple biological conditions. The approach considers three cases for each gene: 1) no differential expression, 2) differential expression without differential splicing and 3) differential splicing. rna-seq, gene expression, differential expression, differential splicing, gene is listed by: OMICtools
has parent organization: University of Michigan; Ann Arbor; USA
PMID:24260225 Free, Available for download, Freely available OMICS_01968 SCR_001683 rSeqDiff: Detecting differential isoform expression from RNA-Seq data using hierarchical likelihood ratio test 2026-08-01 12:01:47 0
QuasiSeq
 
Resource Report
Resource Website
10+ mentions
QuasiSeq (RRID:SCR_001715) QuasiSeq software resource Software package to apply the QL, QLShrink and QLSpline methods to quasi-Poisson or quasi-negative binomial models for identifying differentially expressed genes in RNA-seq data. differential expression, gene, rna-seq, next generation sequencing, gene expression, mrna is listed by: OMICtools PMID:23104842 Free, Available for download, Freely available OMICS_01963 http://cran.r-project.org/web/packages/QuasiSeq/index.html SCR_001715 2026-08-01 12:01:48 20
International Neuroinformatics Coordinating Facility: Blue Gene/L Access
 
Resource Report
Resource Website
International Neuroinformatics Coordinating Facility: Blue Gene/L Access (RRID:SCR_001755) data computation service Through this site, INCF provides he neuroinformatics community with access to an IBM Blue Gene/L supercomputer. INCF owns a share of a BlueGene/L (BG/L) supercomputer located at the Parallel Computer Center (PDC) at The Royal Institute of Technology (KTH) in Stockholm. Allocations are now available through the INCF Secretariat. During an initial evaluation phase, a limited numbers of large-scale computing projects will be selected, based on the suitability of the project for supercomputing. Research groups with limited access to supercomputers at their home institutions are given priority. Approved projects are regularly re-evaluated. New projects are approved based on availability and usage load of the BG/L. The Blue Gene/L supercomputer project is aimed at expanding the horizon of high-performance computing to unprecedented levels of scale and performance. Blue Gene/L is the first supercomputer in the Blue Gene family. The full Blue Gene/L consists of 64 racks containing 65,536 high-performance compute nodes. Each node (nodes and chips are the same in the Blue Gene system) contains two embedded 32-bit PowerPC processors. Furthermore, the same chip that is used for compute nodes is also used for the 1,024 I/O nodes. A three-dimensional torus network and a collective network are used to interconnect all nodes. The full system contains 33 terabytes of main memory; it is designed to achieve 183.5 teraflops peak performance using one of the processors of each node for computation and the other processor for communication, and 367 teraflops using both processors for computation. Another key architectural feature of this supercomputer is the link chip component and five Blue Gene/L networks, the PowerPC 440 core and floating-point enhancements, the on-chip and off-chip distributed memory system, the node- and system-level design for high reliability, and the comprehensive approach to fault isolation. One of the key objectives in Blue Gene/L design is to achieve cost/performance comparable to the COTS (Commodity Off The Shelf) approach, while at the same time incorporating a processor and network combination so powerful that it revolutionizes the performance of supercomputer systems. Sponsors: This resource is supported by the INCF. gene, chip, computation, computing project, memory, neuroinformatics, node, parallel computer, processor, supercomputer THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-10263 SCR_001755 INCF Blue Gene/L Access 2026-08-01 12:01:49 0
MetaDrug
 
Resource Report
Resource Website
1+ mentions
MetaDrug (RRID:SCR_000461) MetaDrug commercial organization A leading systems pharmacology solution that incorporates extensive manually curated information on biological effects of small molecule compounds. Predictive and analytical algorithms look at chemical compounds from different angles in one integrated workflow are available for: * Individual previously described compounds to look up their known information and predict currently unknown properties * Individual newly synthesized or isolated compounds to predict their properties from its structures * Compound libraries to extract known and predict new properties of individual compounds and perform their comparison and prioritization pharmacology, compound, pathway, target, metabolite, prediction, toxicity, indication, metabolism, gene, protein, analysis, drug effect is listed by: OMICtools THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01584 SCR_000461 2026-08-01 12:01:21 1
Functional Biosciences
 
Resource Report
Resource Website
1+ mentions
Functional Biosciences (RRID:SCR_000943) service resource A service that provides low cost DNA sequencing. They utilize microfluidic technology. dna, sequencing, sequence, gene, genome, microfluidic, technology is listed by: ScienceExchange SciEx_9422 http://www.scienceexchange.com/facilities/functional-biosciences-inc SCR_000943 Functional Biosciences Inc. 2026-08-01 12:01:33 2
GISTIC
 
Resource Report
Resource Website
10+ mentions
GISTIC (RRID:SCR_000151) GISTIC software resource Software to identify genes targeted by somatic copy-number alterations (SCNAs) that drive cancer growth. By separating SCNA profiles into underlying arm-level and focal alterations, they improve the estimation of background rates for each category. somatic copy-number alteration, gene is listed by: OMICtools
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA;
Cancer PMID:21527027 Free, Available for download, Freely available OMICS_02296 SCR_000151 GISTIC2.0, GISTIC 2.0, GISTIC 2 2026-08-01 12:01:10 48
FCROS
 
Resource Report
Resource Website
1+ mentions
FCROS (RRID:SCR_006195) FCROS software resource A fold change ranks ordering statistics based software for detecting differentially expressed genes. differentially expressed, gene, fold, statistics, windows, os x, microarray is listed by: OMICtools PMID:24423217 GNU General Public License, v2, v3 OMICS_02234 SCR_006195 fold change rank ordering statistics, fcros: FCROS for detecting differentially expressed genes 2026-08-01 12:03:05 5

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