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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
unifiedWMWqPCR
 
Resource Report
Resource Website
unifiedWMWqPCR (RRID:SCR_001706) software resource Software package that implements the unified Wilcoxon-Mann-Whitney Test for qPCR data. This modified test allows for testing differential expression in qPCR data. standalone software, mac os x, unix/linux, windows, r, gene expression, microtitre plate assay, qpcr, differential expression, multiple comparison, quality control, visualization, qpcr, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24794933 Free, Available for download, Freely available OMICS_03937, biotools:unifiedwmwqpcr https://bio.tools/unifiedwmwqpcr SCR_001706 unifiedWMWqPCR - Unified Wilcoxon-Mann Whitney Test for testing differential expression in qPCR data 2026-08-01 12:02:00 0
ShortRead
 
Resource Report
Resource Website
100+ mentions
ShortRead (RRID:SCR_006813) ShortRead software resource Software package for input, quality assessment and exploration of high-throughput sequence data. Used for input, quality assurance, and basic manipulation of `short read'' DNA sequences such as those produced by Solexa, 454, and related technologies, including exible import of common short read data formats. high throughput sequence data, short read, DNA sequences, short read data is listed by: OMICtools
is listed by: Debian
is listed by: SoftCite
has parent organization: Bioconductor
PMID:19654119 Free, Available for download, Freely available OMICS_01076 https://sources.debian.org/src/r-bioc-shortread/ SCR_006813 ShortRead - Classes and methods for high-throughput short-read sequencing data. 2026-08-01 12:03:13 225
EBCall
 
Resource Report
Resource Website
10+ mentions
EBCall (RRID:SCR_006791) EBCall software resource A software package for somatic mutation detection (including InDels). EBCall uses not only paired tumor/normal sequence data of a target sample, but also multiple non-paired normal reference samples for evaluating distribution of sequencing errors, which leads to an accurate mutaiton detection even in case of low sequencing depths and low allele frequencies. mutation, cancer, genome, sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Tokyo; Tokyo; Japan
PMID:23471004 Copyright conditions, Acknowledgement required biotools:ebcall, OMICS_00084 https://bio.tools/ebcall SCR_006791 EBCall (Empirical Baysian mutation Calling), Empirical Baysian mutation Calling 2026-08-01 12:03:17 19
RamiGO
 
Resource Report
Resource Website
10+ mentions
RamiGO (RRID:SCR_006922) RamiGO software resource Software package with an R interface sending requests to AmiGO visualize, retrieving DAG GO trees, parsing GraphViz DOT format files and exporting GML files for Cytoscape. Also uses RCytoscape to interactively display AmiGO trees in Cytoscape. visualization, analysis, ontology or annotation search engine, ontology or annotation visualization, other analysis, classification, go, graph, network, third party client, windows, mac os x, linux, unix, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
is related to: Cytoscape
is related to: AmiGO
has parent organization: Dana-Farber Cancer Institute
has parent organization: Bioconductor
PMID:23297033 Artistic License, v2 biotools:ramigo, OMICS_02267, nlx_149331 http://bioconductor.org/packages/release/bioc/html/RamiGO.html, https://bio.tools/ramigo SCR_006922 ramigo, RamiGO - AmiGO visualize R interface 2026-08-01 12:03:19 11
ArtificialFastqGenerator
 
Resource Report
Resource Website
10+ mentions
ArtificialFastqGenerator (RRID:SCR_006880) ArtificialFastqGenerator software resource Software to evaluate and improve the accuracy of sequencing error under different experimental conditions. It can identify which components of a system may be suboptimal and which regions of the genome may be problematic. matlab, java, Next Generation Sequencing, aligns reads, reference genome is listed by: OMICtools
is listed by: Debian
PMID:23152858 GNU GPL v3 OMICS_00248, SCR_015979 https://sources.debian.org/src/artfastqgenerator/ SCR_006880 Artfastqgenerator - Ouputs artificial FASTQ files derived from a reference genome 2026-08-01 12:03:14 10
BarraCUDA
 
Resource Report
Resource Website
1+ mentions
BarraCUDA (RRID:SCR_006881) BarraCUDA software resource A sequence mapping software that utilizes the massive parallelism of graphics processing units to accelerate the inexact alignment of short sequence reads to a particular location on a reference genome. It can align a paired-end library containing 14 million pairs of 76bp reads to the Human genome in about 27 minutes (from fastq files to SAM alignment) using a ��380 NVIDIA Geforce GTX 680*. The alignment throughput can be boosted further by using multiple GPUs (up to 8) at the same time. Being based on BWA (http://bio-bwa.sf.net) from the Sanger Institute, BarraCUDA delivers a high level of alignment fidelity and is comparable to other mainstream alignment programs. It can perform gapped alignment with gap extensions, in order to minimise the number of false variant calls in re-sequencing studies. gpu/cuda, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Cambridge; Cambridge; United Kingdom
has parent organization: SourceForge
PMID:22244497
PMID:19451168
Acknowledgement requested OMICS_00650, biotools:barracuda https://bio.tools/barracuda SCR_006881 2026-08-01 12:03:23 4
Myrna
 
Resource Report
Resource Website
1+ mentions
Myrna (RRID:SCR_006951) Myrna software resource A cloud computing tool for calculating differential gene expression in large RNA-seq datasets. It uses Bowtie for short read alignment and R/Bioconductor for interval calculations, normalization, and statistical testing. These tools are combined in an automatic, parallel pipeline that runs in the cloud (Elastic MapReduce in this case) on a local Hadoop cluster, or on a single computer, exploiting multiple computers and CPUs wherever possible. mapreduce, hadoop, cloud computing, differential expression, gene expression, rna-seq, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: ReCount - A multi-experiment resource of analysis-ready RNA-seq gene count datasets
has parent organization: Johns Hopkins University; Maryland; USA
PMID:20701754 Artistic License OMICS_01310, biotools:myrna https://github.com/BenLangmead/myrna, https://bio.tools/myrna SCR_006951 Myrna: Cloud-scale differential gene expression for RNA-seq 2026-08-01 12:03:20 2
FlexProt: flexible protein alignment
 
Resource Report
Resource Website
1+ mentions
FlexProt: flexible protein alignment (RRID:SCR_007306) software resource FlexProt detects the optimal flexible structural alignment of a pair of protein structures. The first structure is assumed to be rigid, while in the second structure potential flexible regions are automatically detected. bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Tel Aviv University; Ramat Aviv; Israel
nif-0000-00159, biotools:flexprot https://bio.tools/flexprot SCR_007306 FlexPROT 2026-08-01 12:03:32 1
Taipan
 
Resource Report
Resource Website
1+ mentions
Taipan (RRID:SCR_007330) Taipan software resource A fast hybrid short-read assembly tool. c, unix/linux, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:19535537 GNU General Public License, v2 OMICS_00035, biotools:taipan https://bio.tools/taipan SCR_007330 2026-08-01 12:03:27 2
CCAT
 
Resource Report
Resource Website
50+ mentions
CCAT (RRID:SCR_001843) CCAT software resource THIS RESOURCE IS OUT OF SERVICE, documented on April 5, 2017, A software package for the analysis of ChIP-seq data with negative control., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Genome Institute of Singapore; Singapore; Singapore
PMID:20371496 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00428, biotools:ccat https://bio.tools/ccat SCR_001843 Control based ChIP-Seq Analysis Tools 2026-08-01 12:01:52 76
S-MART
 
Resource Report
Resource Website
10+ mentions
S-MART (RRID:SCR_001908) S-MART software resource Software toolbox that manages your RNA-Seq and ChIP-Seq data and also produces many different plots to visualize your data. It performs several tasks that are usually required during the analysis of mapped RNA-Seq and ChIP-Seq reads, including data selection and data visualization. It includes the selection (or the exclusion) of the data that overlaps with a reference set, clustering and comparative analysis. It also provides many ways to visualize data: size of the reads, density on the genome, distance with respect to a reference set, and the correlation of two data sets (with cloud plots). A computer science background is not required to run it through a graphical interface and it can be run on any personal computer, yielding results within an hour for most queries. high throughput sequencing, rna-seq, chip-seq, python, linux, ms windows, mac, short-read, selection, visualization, bio.tools, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:21998740 Free, Available for download, Freely available OMICS_01937, biotools:mapperanalyzer, biotools:s-mart https://bio.tools/s-mart, https://bio.tools/mapperanalyzer SCR_001908 2026-08-01 12:01:38 23
SamSPECTRAL
 
Resource Report
Resource Website
1+ mentions
SamSPECTRAL (RRID:SCR_001858) software resource Software that identifies cell population in flow cytometry data. It demonstrates significant advantages in proper identification of populations with non-elliptical shapes, low density populations close to dense ones, minor subpopulations of a major population and rare populations. It samples large data such that spectral clustering is possible while preserving density information in edge weights. More specifically, given a matrix of coordinates as input, SamSPECTRAL first builds the communities to sample the data points. Then, it builds a graph and after weighting the edges by conductance computation, the graph is passed to a classic spectral clustering algorithm to find the spectral clusters. The last stage of SamSPECTRAL is to combine the spectral clusters. The resulting connected components estimate biological cell populations in the data sample. software package, mac os x, unix/linux, windows, r, cell biology, clustering, flow cytometry, stem cell, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
Cancer, HIV PMID:20667133 Free, Available for download, Freely available OMICS_05638, biotools:samspectral https://bio.tools/samspectral SCR_001858 SamSPECTRAL - Identifies cell population in flow cytometry data 2026-08-01 12:01:37 4
CQN
 
Resource Report
Resource Website
1+ mentions
CQN (RRID:SCR_001786) CQN software resource A normalization tool for RNA-Seq data, implementing the conditional quantile normalization method. rna-seq, differential expression, preprocessing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
has parent organization: Johns Hopkins Bloomberg School of Public Health; Maryland; USA
PMID:22285995 Free, Available for download, Freely available OMICS_01949, biotools:cqn https://bio.tools/cqn SCR_001786 Conditional Quantile Normalization 2026-08-01 12:01:50 6
ADaCGH2
 
Resource Report
Resource Website
ADaCGH2 (RRID:SCR_001981) software resource Software for analysis and plotting of array comparative genomic hybridization (CGH) data. It allows usage of Circular Binary Segementation, wavelet-based smoothing (both as in Liu et al., and HaarSeg as in Ben-Yaacov and Eldar), HMM, BioHMM, GLAD, CGHseg. Most computations are parallelized (either via forking or with clusters, including MPI and sockets clusters) and use ff for storing data. standalone software, mac os x, unix/linux, windows, r, copy number variant, microarray, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24532724 Free, Available for download, Freely available biotools:adacgh2, OMICS_03697 https://bio.tools/adacgh2 SCR_001981 ADaCGH2 - Analysis of big data from aCGH experiments using parallel computing and ff objects 2026-08-01 12:02:07 0
PurBayes
 
Resource Report
Resource Website
10+ mentions
PurBayes (RRID:SCR_002068) software resource An MCMC-based algorithm that uses next-generation sequencing data to estimate tumor purity and clonality for paired tumor-normal data. software package, unix/linux, mac os x, windows, r, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: CRAN
PMID:23749958 Free, Available for download, Freely available biotools:purbayes, OMICS_03561 https://bio.tools/purbayes http://cran.r-project.org/web/packages/PurBayes/ SCR_002068 PurBayes: Bayesian Estimation of Tumor Purity and Clonality 2026-08-01 12:02:07 10
DWGSIM
 
Resource Report
Resource Website
50+ mentions
DWGSIM (RRID:SCR_002342) DWGSIM software resource Whole Genome Simulator for Next-Generation Sequencing. next-generation sequencing, whole genome simulation is listed by: OMICtools
is listed by: Debian
GNU General Public License, v2 OMICS_00249 https://sources.debian.org/src/dwgsim/ SCR_002342 2026-08-01 12:02:05 51
BEETL-fastq
 
Resource Report
Resource Website
BEETL-fastq (RRID:SCR_002341) software resource Software tool that not only compresses FASTQ-formatted DNA reads more compactly than gzip but also permits rapid search for k-mer queries within the archived sequences. The full FASTQ record of each matching read or read pair is returned, allowing the search results to be piped directly to any of the many standard tools that accept FASTQ data as input. Searchable compressed archive for DNA reads. Searchable compressed archive, DNA reads, compresses FASTQ-formatted DNA reads, bio.tools, is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Burrows-Wheeler transform
PMID:24950811 Free, Available for download, Freely available OMICS_04900, biotools:beetl https://bio.tools/beetl SCR_002341 2026-08-01 12:02:09 0
GEOquery
 
Resource Report
Resource Website
10+ mentions
GEOquery (RRID:SCR_000146) GEOquery software resource Software that establishes a bridge between GEO and BioConductor. microarray, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Expression Omnibus
is related to: GEO2R
has parent organization: Bioconductor
has parent organization: National Institutes of Health
PMID:17496320 Free, Available for download, Freely available biotools:geoquery, OMICS_01972 https://bio.tools/geoquery, https://sources.debian.org/src/r-bioc-geoquery/ SCR_000146 GEOquery - Get data from NCBI Gene Expression Omnibus (GEO) 2026-08-01 12:01:11 18
GemSIM
 
Resource Report
Resource Website
GemSIM (RRID:SCR_000167) GemSIM software resource A software package for generating realistic simulated next-generation genome sequencing reads with quality score values. The software is written in Python with a command-line user interface. bioinformatics, simulation, sequencing, dna, rna, empirical models, Python, command-line, user interface, metagenomic, resequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
is required by: Wessim
PMID:22336055
DOI:10.1186/1471-2164-13-74
Free, Available for download, Freely available OMICS_01507, biotools:GemSIM https://bio.tools/GemSIM SCR_000167 2026-08-01 12:01:12 0
MIMOSA
 
Resource Report
Resource Website
MIMOSA (RRID:SCR_000184) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Software for modeling count data using Dirichlet-multinomial and beta-binomial mixtures with applications to single-cell assays. software package, mac os x, unix/linux, windows, r, cell based assay, flow cytometry, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23887981 THIS RESOURCE IS NO LONGER IN SERVICE biotools:mimosa, OMICS_05642 https://bio.tools/mimosa SCR_000184 MIMOSA - Mixture Models for Single-Cell Assays, MIMOSA: Mixture Models For Single Cell Assays 2026-08-01 12:01:09 0

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