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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
PyNWB
 
Resource Report
Resource Website
1+ mentions
PyNWB (RRID:SCR_017452) software application, software resource Software Python package for working with Neurodata stored in Neurodata Without Borders files. Software providing API allowing users to read and create NWB formatted HDF5 files. Developed in support to NWB project with aim of spreading standardized data format for cellular based neurophysiology information. Neurodata, stored, NWB, file, share, standardized, data, format, neurophysiology, BRAIN Initiative uses: Hierarchical Data Modeling Framework
is used by: NWB Explorer
is recommended by: BRAIN Initiative
is listed by: OMICtools
is listed by: Neurodata Without Borders
is related to: Neurodata Extensions Catalog
is related to: HDMF Common Schema
is related to: NWB Inspector
Kavli Foundation ;
General Electric ;
Howard Hughes Medical Institute ;
Allen Institute for Brain Science ;
NSF 0855272;
International Neuroinformatics Coordinating Facility ;
NIH BRAIN Initiative R24 MH116922
PMID:26590340 Free, Available for downloading, Freely available https://github.com/NeurodataWithoutBorders/pynwb https://github.com/AllenInstitute/nwb-api SCR_017452 2026-08-04 09:44:10 4
Chromas
 
Resource Report
Resource Website
10+ mentions
Chromas (RRID:SCR_000598) Chromas commercial organization, software resource Software ideal for the most basic of sequencing projects, where assembly of multiple sequences is not required., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01016, biotools:chromas https://bio.tools/chromas SCR_000598 2026-08-04 09:40:10 16
Subread
 
Resource Report
Resource Website
1000+ mentions
Subread (RRID:SCR_009803) data processing software, software application, software resource Software package for high-performance read alignment, quantification and mutation discovery.General purpose read aligner which can be used to map both genomic DNA-seq reads and RNA-seq reads. Subread aligner as fast, accurate and scalable read mapping by seed-and-vote.These programs were also implemented in Bioconductor R package Rsubread. read alignment, DNA-seq reads mapping, RNA-seq reads mapping, mutation discovery, , bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Rsubread
has parent organization: University of Melbourne; Victoria; Australia
Australian National Health and Medical Research Council ;
Victorian State Government Operational Infrastructure Support ;
Australian Government
PMID:23558742 Free, Freely available OMICS_01255, biotools:subread https://bio.tools/subread, https://sources.debian.org/src/subread/ SCR_009803 2026-08-04 09:42:28 1854
Trim Galore
 
Resource Report
Resource Website
5000+ mentions
Rating or validation data
Trim Galore (RRID:SCR_011847) Trim Galore! data processing software, software application, software resource Software tool to automate quality and adapter trimming as well as quality control, with some added functionality to remove biased methylation positions for RRBS sequence files for directional, non-directional or paired-end sequencing. Wrapper around Cutadapt and FastQC to consistently apply adapter and quality trimming to FastQ files, with extra functionality for Reduced Representation Bisulfite Sequencing data. Automate, quality, adapter, trimming, remove, biased, methylation, position, RRBS, reduced, representation, bisulfite, data, sequence, wrapper, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Babraham Institute
works with: cutadapt
Free, Available for download, Freely available biotools:trim_galore, OMICS_01096, SCR_016946 https://github.com/FelixKrueger/TrimGalore, https://bio.tools/trim_galore, https://sources.debian.org/src/trim-galore/ SCR_011847 TrimGalore 2026-08-04 09:42:52 6255
TiltPicker
 
Resource Report
Resource Website
TiltPicker (RRID:SCR_016674) data processing software, software application, software resource Software tool to facilitate particle selection in single particle electron microscopy. An interactive graphical interface application designed to streamline the selection of particle pairs from tilted-pair datasets. Designed to work with existing software tools for image processing. particle, selection, single, electron, microscopy, interactive, graphical, interface, tilted, pair, dataset, image, processing is listed by: OMICtools NCRR RR23093;
NCRR RR17573
PMID:19374019 Free, Available for download, Freely available http://emg.nysbc.org/redmine/projects/appion/wiki/Appion_Home SCR_016674 2026-08-04 09:43:59 0
Racon
 
Resource Report
Resource Website
100+ mentions
Racon (RRID:SCR_017642) data processing software, software application, software resource Software tool as de novo genome assembly from long uncorrected reads. Used to correct raw contigs generated by rapid assembly methods which do not include consensus step. Supports data produced by Pacific Biosciences and Oxford Nanopore Technologies. Assembly, de novo, long, uncorrected, read, raw, contig, consensus, step, data, sequence, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
Croatian Science Foundation ;
Croatian Academy of Sciences and Arts ;
A*STAR ;
Singapore
DOI:10.1101/068122 Free, Available for download, Freely available OMICS_25714, biotools:Racon, BioTools:Racon https://bio.tools/Racon, https://sources.debian.org/src/racon/ SCR_017642 2026-08-04 09:44:10 149
TransDecoder
 
Resource Report
Resource Website
1000+ mentions
TransDecoder (RRID:SCR_017647) data processing software, software application, standalone software, software resource Software tool to identify candidate coding regions within transcript sequences, such as those generated by de novo RNA-Seq transcript assembly using Trinity, or constructed based on RNA-Seq alignments to genome using Tophat and Cufflinks.Starts from FASTA or GFF file. Can scan and retain open reading frames (ORFs) for homology to known proteins by using BlastP or Pfam search and incorporate results into obtained selection. Predictions can then be visualized by using genome browser such as IGV. Identify, candidate, coding, region, transcript, sequence, de novo, RNAseq, assembly, alignment, genome, open, reading, frame, homology, protein, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:transDecoder, OMICS_10852 https://bio.tools/TransDecoder, https://sources.debian.org/src/transdecoder/, https://github.com/TransDecoder/TransDecoder/wiki SCR_017647 , Find Coding Regions Within Transcripts 2026-08-04 09:44:15 1309
Recognition of Errors in Assemblies using Paired Reads
 
Resource Report
Resource Website
1+ mentions
Recognition of Errors in Assemblies using Paired Reads (RRID:SCR_017625) REAPR data processing software, software application, software resource Software tool to identify errors in genome assemblies without need for reference sequence. Can be used in any stage of assembly pipeline to automatically break incorrect scaffolds and flag other errors in assembly for manual inspection. Reports mis-assemblies and other warnings, and produces new broken assembly based on error calls. Identify, error, genome, assembly, without, reference, sequence, incorrect, scaffold, error is listed by: Debian
is listed by: OMICtools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
European Union ;
Wellcome Trust ;
JSPS KAKENHI
PMID:23710727 Free, Available for download, Freely available OMICS_04068 https://sources.debian.org/src/reapr/ SCR_017625 2026-08-04 09:44:10 2
NanoFilt
 
Resource Report
Resource Website
100+ mentions
NanoFilt (RRID:SCR_016966) data processing software, software application, software resource Software tool written in Python to perform its filtering based on mean read quality and GC content and read length. Used for filtering and trimming of long read sequencing data. filtering, trimming, long, sequencing, data, read is listed by: OMICtools
is listed by: Debian
Free, Available for download, Freely available https://sources.debian.org/src/nanofilt/ SCR_016966 2026-08-04 09:44:01 268
ScaffMatch
 
Resource Report
Resource Website
1+ mentions
ScaffMatch (RRID:SCR_017025) data processing software, software application, software resource Software tool as scaffolding algorithm based on maximum weight matching able to produce high quality scaffolds from next generation sequencing data (reads and contigs). Able to handle reads with both short and long insert sizes. scaffolding, algorithm, maximum, weight, matching, next, generation, sequencing, data, read, contig, bio.tools uses: Python Programming Language
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Georgia State University; Georgia; USA
NSF IIS 0916401 PMID:25890305 Free, Available for download, Freely available biotools:scaffmatch, OMICS_08198 http://alan.cs.gsu.edu/NGS/?q=content/scaffmatch, https://bio.tools/scaffmatch SCR_017025 2026-08-04 09:44:03 1
Rosalind
 
Resource Report
Resource Website
10+ mentions
Rosalind (RRID:SCR_006233) Rosalind open course, training resource, online course A software infrastructure, course and tool set for teaching bioinformatics, and biology through the use of models. This platform for learning bioinformatics through problem solving aims to make learning bioinformatics fun and easy. Learning bioinformatics usually requires solving computational problems of varying difficulty that are extracted from real challenges of molecular biology. Rosalind offers an array of intellectually stimulating problems that grow in biological and computational complexity; each problem is checked automatically, so that the only resource required to learn bioinformatics is an internet connection. Rosalind also promises to facilitate improvements in standard bioinformatics education by providing a vital teaching aid and a central homework resource. Rosalind is inspired by Project Euler, Google Code Jam, and the ever growing movement of free online courses. The project''s name commemorates Rosalind Franklin, whose X-ray crystallography with Raymond Gosling facilitated the discovery of the DNA double helix by Watson and Crick. We hope that Rosalind will inspire a new generation of bioinformatics students by attracting biologists who want to develop vital programming skills at their own pace in a unique environment as well as programmers who have never been exposed to some of the stimulating computational problems generated by molecular biology. bioinformatics, biology, model, programming, teaching, course, problem solving, python, algorithm, molecular biology is listed by: OMICtools
has parent organization: University of California at San Diego; California; USA
has parent organization: Saint Petersburg Academic University; Saint Petersburg; Russia
Howard Hughes Medical Institute ;
Ministry of Education and Science of the Russian Federation ;
Megagrant
nlx_151793, OMICS_01709 SCR_006233 2026-08-04 09:41:33 32
skewer
 
Resource Report
Resource Website
10+ mentions
skewer (RRID:SCR_001151) skewer data processing software, software application, software resource Software program for adapter trimming that is specially designed for processing Illumina paired-end sequences. illumina, unix/linux, c++, adapter trimming, paired-end, sequence, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:24925680 Free, Available for download, Freely available OMICS_02106, biotools:skewer https://bio.tools/skewer, https://sources.debian.org/src/skewer/, https://github.com/relipmoc/skewer SCR_001151 skewer - A fast and sensitive adapter trimmer for illumina paired-end sequences 2026-08-04 09:40:19 11
SNPAAMapper
 
Resource Report
Resource Website
SNPAAMapper (RRID:SCR_002012) SNPAAMapper data processing software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 19,2025. A downstream variant annotation program that can effectively classify variants by region (e.g. exon, intron, etc), predict amino acid change type (e.g. synonymous, non-synonymous mutation, etc), and prioritize mutation effects (e.g. CDS versus 5?UTR, etc). Major features: * The pipeline accepts the VCF (Variant Call Format) input file in tab-delimited format and processes the vcf input file containing all cases (G5, lowFreq, and novel) * The variant mapping step has the option of letting users select whether they want to report the bp distance between each identified intron variant and its nearby exon * The pipeline can deal with VCF files called by different SAMTools versions (0.1.18 and older ones) and also offers flexibility in dealing with vcf input files generated using SAMTools with two or three samples * The spreadsheet result file contains full protein sequences for both ref and alt alleles, which makes it easier for downstream protein structure/function analysis tools to take single nucleotide polymorphism, amino acid, variant, annotation, exon, intron, mutation, next-generation sequencing, perl, downstream analysis, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Michigan Medical School; Michigan; USA
PMID:24250114 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01922, biotools:snpaamapper https://bio.tools/snpaamapper SCR_002012 SNPAAMapper - A SNP Amino Acid Mapping tool 2026-08-04 09:40:32 0
MUMmerGPU
 
Resource Report
Resource Website
1+ mentions
MUMmerGPU (RRID:SCR_001200) MUMmerGPU data processing software, software application, software resource Software tool as high throughput DNA sequence alignment program that runs on nVidia G80-class GPUs. Aligns sequences in parallel on video card to accelerate widely used serial CPU program MUMmer. parallel computation 4, high-throughput sequencing, sequence alignment, dna, graphics processing unit is listed by: OMICtools
is related to: MUMmer
has parent organization: SourceForge
has parent organization: University of Maryland; Maryland; USA
NLM R01 LM006845;
NIGMS R01 GM083873
PMID:20161021 Free, Available for download, Freely available OMICS_02151 SCR_001200 High-throughput sequence alignment using Graphics Processing Units 2026-08-04 09:40:20 5
University of Zurich SCRM - Cell-and Tissue Biobank
 
Resource Report
Resource Website
University of Zurich SCRM - Cell-and Tissue Biobank (RRID:SCR_004959) SCRM-CTBB cell repository, material resource, biomaterial supply resource The SCRM-CTBB offers state-of-the-art infrastructure and technologies (e.g. cryogenic work bench, semiautomatic cryogenic storage system, uninterrupted cooling chain) and is structured into two areas, including research and a GMP/GCP regulated therapeutic applications. Research: For pre-clinical studies, the SCRM-CTBB provides researchers guidance regarding cell and tissue cryo-preservation, comprising registration, handling, storage and distribution. In order to ensure complete traceability on samples and belonging information all processes are controlled by a Laboratory Information Management System (LIMS) and Quality Assurance (QA) system. The SCRM Biobank is designed to create database that allows connection with other biobanks nationally and internationally. This meta-data file will enable a unique scientific resource for interdisciplinary research. For every new study a contract is established describing the study and the disposition rights. Assistance in writing Biobank Agreements (BAs) and Material Transfer Agreements (MTAs) is provided. Therapeutical applications: As a new feature, apart from research, the SCRM Biobank enables the asservation and preservation of cells and tissues under GMP conditions for later therapeutic use. A special focus will be on a conceptional combination of private and public umbilical cord blood banking (hybrid banking), which allows autologous and/or allogeneic cell applications. cell, tissue, umbilical cord blood, blood, cryopreserved, therapy, research, clinical, frozen, transplantation is listed by: One Mind Biospecimen Bank Listing
is listed by: Debian
is listed by: OMICtools
has parent organization: University of Zurich; Zurich; Switzerland
Public: The SCRM Biobank is designed to create database that allows connection with other biobanks nationally and internationally. This meta-data file will enable a unique scientific resource for interdisciplinary research. nlx_143985, OMICS_07231 https://sources.debian.org/src/scrm/ SCR_004959 University of Zurich SCRM - Cell Tissue Biobank, UZH Swiss Center for Regenerative Medicine Cell-and Tissue Biobank, University of Zurich SCRM - Cell and Tissue Biobank, UZH SCRM-CTBB, SCRM Biobank, SCRM - Cell-and Tissue Biobank (CTBB), University of Zurich Swiss Center for Regenerative Medicine Cell-and Tissue Biobank, UZH SCRM - Cell-and Tissue Biobank, SCRM - Cell- Tissue Biobank 2026-08-04 09:41:16 0
HTqPCR
 
Resource Report
Resource Website
50+ mentions
HTqPCR (RRID:SCR_003375) HTqPCR data processing software, software application, software resource Software package for the analysis of Ct values from high throughput quantitative real-time PCR (qPCR) assays across multiple conditions or replicates. The input data can be from spatially-defined formats such ABI TaqMan Low Density Arrays or OpenArray; LightCycler from Roche Applied Science; the CFX plates from Bio-Rad Laboratories; conventional 96- or 384-well plates; or microfluidic devices such as the Dynamic Arrays from Fluidigm Corporation. HTqPCR handles data loading, quality assessment, normalization, visualization and parametric or non-parametric testing for statistical significance in Ct values between features (e.g. genes, microRNAs). data import, differential expression, gene expression, microtitre plate assay, multiple comparison, preprocessing, quality control, visualization, qpcr, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
has parent organization: European Bioinformatics Institute
PMID:19808880 Free, Available for download, Freely available biotools:htqpcr, OMICS_02314 https://bio.tools/htqpcr SCR_003375 HTqPCR - Automated analysis of high-throughput qPCR data 2026-08-04 09:40:53 74
NanoStringNorm
 
Resource Report
Resource Website
100+ mentions
NanoStringNorm (RRID:SCR_003382) NanoStringNorm data processing software, software application, software resource Software package for normalizing, diagnostics and visualization of NanoString nCounter data. Key features include an extensible environment for method comparison and new algorithm development, integrated gene and sample diagnostics, and facilitated downstream statistical analysis. normalization, nanostring ncounter, mirna, mrna, r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Ontario Institute for Cancer Research
PMID:22513995 Free, Available for download, Freely available OMICS_02308, biotools:nanostringnorm https://www.rdocumentation.org/packages/NanoStringNorm/versions/1.2.1.1/topics/NanoStringNorm SCR_003382 NanoStringNorm: Normalize NanoString miRNA and mRNA data 2026-08-04 09:40:54 134
SOAPaligner/soap2
 
Resource Report
Resource Website
100+ mentions
SOAPaligner/soap2 (RRID:SCR_005503) SOAPaligner, SOAP2 data processing software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 12,2024. Updated version of SOAP software for short oligonucleotide alignment that features in super fast and accurate alignment for huge amounts of short reads generated by Illumina/Solexa Genome Analyzer., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. next generation sequencing, alignment, short read, oligonucleotide, single-read, pair-end, resequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SOAP
PMID:19497933
DOI:10.1093/bioinformatics/btn025
THIS RESOURCE IS NO LONGER IN SERVICE biotools:soap2 https://bio.tools/soap2, https://sources.debian.org/src/soapaligner/ SCR_005503 2026-08-04 09:41:22 322
COILS: Prediction of Coiled Coil Regions in Proteins
 
Resource Report
Resource Website
100+ mentions
COILS: Prediction of Coiled Coil Regions in Proteins (RRID:SCR_008440) data processing software, software application, software resource COILS is a program that compares a sequence to a database of known parallel two-stranded coiled-coils and derives a similarity score. By comparing this score to the distribution of scores in globular and coiled-coil proteins, the program then calculates the probability that the sequence will adopt a coiled-coil conformation. software, prediction, database, sequence, coil, globular, protein, probability, bio.tools, FASEB list is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1126/science.252.5009.1162 biotools:ncoils, OMICS_07850, nif-0000-30263 https://bio.tools/ncoils, https://sources.debian.org/src/ncoils/ https://sources.debian.org/src/ncoils/ SCR_008440 COILS Server 2026-08-04 09:42:09 164
epigenomix
 
Resource Report
Resource Website
1+ mentions
epigenomix (RRID:SCR_006407) epigenomix data processing software, software application, software resource Software package for the integrative analysis of microarray based gene expression and histone modification data obtained by ChIP-seq. The package provides methods for data preprocessing and matching as well as methods for fitting bayesian mixture models in order to detect genes with differences in both data types. epigenetic, gene expression, microarray, histone modification, chip-seq, classification, differential expression, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24403540 GNU Lesser General Public License, v3 biotools:epigenomix, OMICS_02205 https://bio.tools/epigenomix SCR_006407 epigenomix - Epigenetic and gene expression data normalization and integration with mixture models 2026-08-04 09:41:35 2

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