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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Pscan-ChIP
 
Resource Report
Resource Website
1+ mentions
Pscan-ChIP (RRID:SCR_010885) Pscan-ChIP data analysis service, production service resource, analysis service resource, service resource Web server that, starting from a collection of genomic regions derived from a ChIP-Seq experiment, scans them using motif descriptors like JASPAR or TRANSFAC position-specific frequency matrices, or descriptors uploaded by users, and it evaluates both motif enrichment and positional bias within the regions according to different measures and criteria. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:23748563
DOI:10.1093/nar/gkt448
biotools:pscanchip, OMICS_00490 https://bio.tools/pscanchip, https://sources.debian.org/src/pscan-chip/ SCR_010885 2026-08-06 09:27:45 5
CUPSAT
 
Resource Report
Resource Website
50+ mentions
CUPSAT (RRID:SCR_010773) CUPSAT data analysis service, production service resource, analysis service resource, service resource A tool to predict changes in protein stability upon point mutations. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:16845001 biotools:cupsat, OMICS_00128 https://bio.tools/cupsat SCR_010773 Cologne University Protein Stability Analysis Tool, CUPSAT: Cologne University Protein Stability Analysis Tool 2026-08-06 09:27:44 74
LS-SNP/PDB
 
Resource Report
Resource Website
1+ mentions
LS-SNP/PDB (RRID:SCR_010774) LS-SNP/PDB data analysis service, production service resource, analysis service resource, service resource A web tool for genome-wide annotation of human SNPs. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Johns Hopkins University; Maryland; USA
OMICS_00131, biotools:ls-snp https://bio.tools/ls-snp SCR_010774 2026-08-06 09:27:40 3
Vector Alignment Search Tool
 
Resource Report
Resource Website
10+ mentions
Vector Alignment Search Tool (RRID:SCR_010655) VAST production service resource, analysis service resource, service resource VAST is a computer algorithm developed at NCBI and used to identify similar protein 3-dimensional structures by purely geometric criteria, and to identify distant homologs that cannot be recognized by sequence comparison. Related structures for every structure in MMDB are pre-computed using VAST and accessible via links on the MMDB Structure Summary pages. The VAST Search page also allows you to compare the coordinates of a newly resolved structure in PDB format against all structures in MMDB to find its neighbors. Protein structure neighbors in Entrez are determined by direct comparison of 3-dimensional protein structures with the VAST algorithm. Each of the more than 87,804 domains in MMDB is compared to every other one. From the MMDB Structure summary pages, retrieved via Entrez, structure neighbors are available for protein chains and individual structural domains. If you already know a PDB/MMDB-Id you can try this at once, using the input form in the right column. VAST Search is a service that allows searching for structural neighbors starting with a set of 3D-coordinates specified by the user. This service is meant to be used with newly determined protein structures that are not yet part of MMDB. Structure neighbors for proteins already in MMDB have been pre-computed and can simply be looked up from MMDB''s Structure summary pages! gold standard, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: NCBI Structure
has parent organization: NCBI
PMID:8804824
PMID:8710828
nlx_68740, biotools:vast https://bio.tools/vast SCR_010655 Vector Alignment Search Tool (VAST) 2026-08-06 09:27:42 17
PlantTFcat
 
Resource Report
Resource Website
10+ mentions
PlantTFcat (RRID:SCR_010898) PlantTFcat data analysis service, production service resource, analysis service resource, service resource A web-based analysis tool that is designed to identify and categorize plant TF/TR/CR genes from genome-scale protein and nucleic acid sequences by systematically analyzing InterProScan domain patterns in protein sequences., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Samuel Roberts Noble Foundation
PMID:24219505 THIS RESOURCE IS NO LONGER IN SERVICE biotools:planttfcat, OMICS_00559 https://bio.tools/planttfcat SCR_010898 PlantTFcat: An Online Plant Transcription Factor and Transcriptional Regulator Categorization and Analysis Tool 2026-08-06 09:27:45 44
ArrayPipe
 
Resource Report
Resource Website
10+ mentions
ArrayPipe (RRID:SCR_010934) ArrayPipe data analysis service, production service resource, analysis service resource, service resource A flexible tool for visualizing and analyzing your two-colour microarray slides. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
OMICS_00744, biotools:arraypipe https://bio.tools/arraypipe SCR_010934 2026-08-06 09:27:41 15
PREDDIMER
 
Resource Report
Resource Website
10+ mentions
PREDDIMER (RRID:SCR_011963) PREDDIMER data analysis service, production service resource, analysis service resource, service resource Prediction tool to reconstruct putative dimer conformations for given sequences of transmembrane protein fragments, which are considered as ideal alpha-helices. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:24202542 Free OMICS_01614, biotools:preddimer https://bio.tools/preddimer SCR_011963 PREDDIMER - Prediction tool for an ensemble of transmembrane ?-helical dimer conformations 2026-08-06 09:27:50 15
HH-suite
 
Resource Report
Resource Website
10+ mentions
HH-suite (RRID:SCR_016133) sequence analysis software, software resource, data analysis software, software toolkit, data processing software, software application Software package for sensitive protein sequence searching based on the pairwise alignment of hidden Markov models (HMMs). Used for sequence-based protein function and structure prediction what depends on sequence-search sensitivity and accuracy of the resulting sequence alignments. protein, sensitive sequence search, pairwise alignment, multiple database, homologous structure, prediction, modeling, bio.tools is listed by: Debian
is listed by: bio.tools
the Deutsche Forschungsgemeinschaft grant SFB646;
Ludwig-Maximilians Universität Munich ;
Excellence Initiative of the Bundesministerium für Bildung und Forschung
DOI:10.1186/s12859-019-3019-7 Free, Available for download, Freely available biotools:hh-suite https://bio.tools/hh-suite http://toolkit.genzentrum.lmu.de/sections/search SCR_016133 2026-08-06 09:28:46 49
DESeq2
 
Resource Report
Resource Website
10000+ mentions
DESeq2 (RRID:SCR_015687) software resource, software tool, data analysis software, data processing software, software application Software package for differential gene expression analysis based on the negative binomial distribution. Used for analyzing RNA-seq data for differential analysis of count data, using shrinkage estimation for dispersions and fold changes to improve stability and interpretability of estimates. differential, gene, expression, analysis, binominal, distribution, RNA-seq data, Bioconductor, bio.tools is used by: Glimma
is used by: TEtranscripts
is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: SARTools
works with: tximport
International Max Planck Research School for Computational Biology and Scientific Computing ;
NCI T32 CA009337;
European Union’s 7th Framework Programme
Free, Available for download, Freely available biotools:deseq2 https://github.com/mikelove/DESeq2, https://bio.tools/deseq2 SCR_015687 2026-08-06 09:28:42 43994
Pilon
 
Resource Report
Resource Website
1000+ mentions
Pilon (RRID:SCR_014731) sequence analysis software, software resource, data analysis software, data processing software, software application Software tool to automatically improve draft assemblies and find variation among strains, including large event detection. FASTA files of genome along with one or more BAM files of reads aligned as input. Read alignment analysis is used to identify inconsistencies between input genome and evidence in reads, then attempts to make improvements to genome. automatically, improve, draft, assembly, variation, strain, genome, read, alignment, analysis, inconsistency, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is related to: shovill
is hosted by: GitHub
DOI:10.1371/journal.pone.0112963
DOI:10.1371/journal.pone.0112963
Available for download, Acknowledgement requested OMICS_14553, biotools:pilon https://github.com/broadinstitute/pilon/wiki, https://bio.tools/pilon, https://sources.debian.org/src/pilon/ SCR_014731 2026-08-06 09:28:23 3102
RepeatModeler
 
Resource Report
Resource Website
1000+ mentions
RepeatModeler (RRID:SCR_015027) sequence analysis software, software resource, data analysis software, data processing software, software application Sequence analysis software that performs repeat family identification and creates models for sequence data. RepeatModeler utilizes RepeatScout and RECON to identify repeat element boundaries and family relationships., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. sequence analysis, sequence repeats, repeat identification, bio.tools uses: RepeatScout
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Dfam
Institute for Systems Biology ;
NHGRI R44 HG02244;
NHGRI R01 HG002939
THIS RESOURCE IS NO LONGER IN SERVICE biotools:repeatmodeler https://bio.tools/repeatmodeler SCR_015027 2026-08-06 09:28:31 3193
Morpheus
 
Resource Report
Resource Website
500+ mentions
Morpheus (RRID:SCR_014975) software resource, 3d visualization software, data processing software, data visualization software, software application, simulation software Modeling and simulation environment for study of multi scale and multicellular systems. Users can construct and simulate models of gene regulation, signaling pathways, tissue patterning and morphogenesis and explore the effects of multiscale feedbacks between these processes. Morpheus can render 2D and 3D models using graphical user interface. simulation, modeling, multicellular, systems biology, cell-based models, data visualization, differential equations, reaction-diffusion systems, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Dresden University of Technology; Saxony; Germany
BMBF 0315734;
BMBF 0316169;
DFG
PMID:24443380 Free, Available for download, Freely available biotools:morpheus-framework https://gitlab.com/morpheus.lab/morpheus, https://bio.tools/morpheus-framework https://imc.zih.tu-dresden.de/wiki/morpheus SCR_014975 2026-08-06 09:28:31 694
MEBS: Multigenomic Entropy-Based Score
 
Resource Report
Resource Website
1+ mentions
MEBS: Multigenomic Entropy-Based Score (RRID:SCR_015708) MEBS data analysis software, software application, software resource, data processing software Open source software to evaluate, quantify, compare, and predict the metabolic machinery of interest in large ‘omic’ datasets. This protocol finds informative protein families and uses them to score metagenomic sets. metagenomics analysis, metabolism, fasta file, protein analysis, omic dataset, bio.tools is listed by: bio.tools
is listed by: Debian
Open source, Available for download biotools:mebs https://bio.tools/mebs SCR_015708 metagenome_Pfam_score, Multigenomic Entropy-Based Score, Multigenomic Entropy-Based Score (MEBS) 2026-08-06 09:28:42 1
RNA FRABASE - RNA FRAgments search engine and dataBASE
 
Resource Report
Resource Website
RNA FRABASE - RNA FRAgments search engine and dataBASE (RRID:SCR_012808) RNA FRABASE d spatial image, service resource, production service resource, data analysis service, data or information resource, analysis service resource, database Engine and database to search the three-dimensional fragments within 3D RNA structures using as an input the sequence(s) and / or secondary structure(s) given in the dot-bracket notation. The database contains RNA sequences and secondary structures, described in the dot-bracket notation, derived from PDB-deposited RNA structures and their complexes. It also contains atom coordinates of the unmodified and modified nucleotide and nucleoside residues extracted from the PDB-deposited RNA structures, as well as torsion and pseudotorsion angle values, sugar pucker parameters and classification of base pair types given for the PBD-deposited RNA structures. Knowledge of the three dimensional RNA structure is crucial for all fields of biomolecular research. In contrast to the protein field, only about 1.300 experimentally derived structures of RNAs are deposited in the Protein Data Bank (PDB). To complement the results of experimental studies, new approaches based on bioinformatics and calculation are pursued in several laboratories to make tertiary RNA structure prediction possible. RNA FRABASE version 2.0 should greatly facilitate various RNA structure modelling approaches, RNA structure analysis and motif searching. If one compares the three dimensional RNA structure to a spatial puzzle, the RNA FRABASE allows to pull out a defined piece of this puzzle - the 3D RNA fragment. The architecture of the web-accessible RNA FRABASE engine and database is based on the following information path: PDB-deposited RNA structures �� RNA sequences and secondary structures described in the dot-bracket notation �� secondary structures of RNA fragments �� 3D RNA fragments. RNA FRABASE 2.0 also stores data and conformational parameters in order to provide on the spot structural filters to explore the three-dimensional RNA structures. An instant visualization of the 3D RNA structures is provided. structural element, secondary structure, rna, rna structure, 3d rna fragment, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: Polish Academy of Sciences Poznan; Poznan; Poland
Foundation for Polish Science SP 01/04;
Ministry of Education and Science 3T09A014 29;
Polish Ministry of Science and Higher Education PBZ-MniSW-07/1/2007/01;
Polish Ministry of Science and Higher Education NN 519314635
PMID:20459631
PMID:17921499
nif-0000-03413, biotools:rna_frabase https://bio.tools/rna_frabase SCR_012808 RNA FRAgments search engine dataBASE, RNA FRAgments search engine and dataBASE, RNA FRABASE - RNA FRAgments search engine dataBASE 2026-08-06 09:28:04 0
Roary
 
Resource Report
Resource Website
500+ mentions
Roary (RRID:SCR_018172) sequence analysis software, software resource, data analysis software, data processing software, software application Software tool for rapid large scale prokaryote pan genome analysis. Builds large scale pan genomes, identifying core and accessory genes. Makes construction of pan genome of thousands of prokaryote samples on standard desktop without compromising on accuracy of results. Not intended for meta genomics or for comparing extremely diverse sets of genomes. Genome analysis, prokaryote pan genome, pan genome, gene identification, analysis, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
works with: Scoary
Wellcome Trust PMID:26198102 Free, Available for download, Freely available OMICS_09491, biotools:roary https://github.com/sanger-pathogens/Roary, https://bio.tools/roary, https://sources.debian.org/src/roary/ SCR_018172 2026-08-06 09:29:17 602
R/qtl2
 
Resource Report
Resource Website
10+ mentions
R/qtl2 (RRID:SCR_018181) data analysis software, software application, software resource, data processing software Software R package for mapping quantitative trait loci with high dimensional data and multiparent populations. Used for analysis of high dimensional data and complex crosses. Interactive software environment for mapping quantitative trait loci in experimental populations.R/qtl2 software expands scope of R/qtl software package to include multiparent populations derived from more than two founder strains, such as Collaborative Cross and Diversity Outbred mice, heterogeneous stocks, and MAGIC plant populations. High density genotyping data, molecular phenotype, gene expression, proteomics, mapping trait loci, diversity outbred mice, bio.tools is listed by: Debian
is listed by: bio.tools
NIGMS R01 GM074244;
NIGMS R01 GM070683;
NIGMS R01 GM123489
PMID:30591514 Free, Available for download, Freely available biotools:R_qtl2, SCR_020965 https://bio.tools/R_qtl2, https://kbroman.org/qtl2, https://github.com/rqtl/qtl2 SCR_018181 QTL, R/quantitative trait loci, QTL2, Quantitative Trait Locus 2, quantitative trait loci 2, R/qtl, qtl2 2026-08-06 09:29:21 13
StringTie
 
Resource Report
Resource Website
1000+ mentions
StringTie (RRID:SCR_016323) sequence analysis software, software resource, data analysis software, data processing software, software application Software application for assembling of RNA-Seq alignments into potential transcripts. It enables improved reconstruction of a transcriptome from RNA-seq reads. This transcript assembling and quantification program is implemented in C++ . assembling, RNA, sequence, transcript, gene, alignment, reconstruction, read, analysis, process, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
the Cancer Prevention and Research Institute of Texas ;
NHGRI R01 HG006677;
NIGMS R01 GM105705;
NHGRI R01 HG006102;
NCI R01 CA120185;
NCI R01 CA134292
PMID:25690850
DOI:10.1038/nbt.3122
Open source, Free, Freely available, Available for download biotools:stringtie, OMICS_07226 https://github.com/gpertea/stringtie, https://bio.tools/stringtie, https://sources.debian.org/src/stringtie/ SCR_016323 2026-08-06 09:28:53 4072
CMap
 
Resource Report
Resource Website
100+ mentions
CMap (RRID:SCR_016204) data set, software resource, data or information resource, web application, database Dataset of cellular signatures that catalogs transcriptional responses of human cells to chemical and genetic perturbation. CMap contains perturbagens, expression signatures, and small molecules from cell lines. data, set, connectivity, gene, expression, database, heat map, drug, tool, perturbational, perturbagen, signature, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: Broad Institute
Free for academic use, Subscription for commercial use, Available for download, Acknowledgement requested biotools:CMap https://bio.tools/CMap SCR_016204 LINCS CMap L1000, LINCS L1000, LINCS CMap, ConnectivityMap, Connectivity Map 2026-08-06 09:28:46 483
SMARTdenovo
 
Resource Report
Resource Website
100+ mentions
SMARTdenovo (RRID:SCR_017622) software resource, image analysis software, alignment software, data processing software, software application Software tool as de novo assembler for PacBio and Oxford Nanopore data. It produces assembly from all-vs-all raw read alignments without error correction stage. Allows to read overlapping, rescue missing overlaps, identify low-quality regions and chimaera and produce better consensus. De novo, assembler, PacBio, Oxford Nanopore, data, sequence, raw, read, alignment, error, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available BioTools:SMARTdenovo, biotools:SMARtdenovo https://bio.tools/SMARTdenovo, https://bio.tools/SMARTdenovo, https://bio.tools/SMARTdenovo SCR_017622 2026-08-06 09:29:07 159
pheatmap
 
Resource Report
Resource Website
1000+ mentions
pheatmap (RRID:SCR_016418) pheatmap data acquisition software, software resource, image acquisition software, software toolkit, data processing software, software application Software tool as a function in R to draw clustered heatmaps for better control over graphical parameters. draw, clustered, heatmap, control, graphical, parameter, size, shape, text, bio.tools is used by: ClustVis
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
is related to: CRAN
Free, Available for download, Freely available biotools:pheatmap, OMICS_26726 https://github.com/raivokolde/pheatmap, https://cran.r-project.org/web/packages/pheatmap/pheatmap.pdf, https://bio.tools/pheatmap, https://sources.debian.org/src/r-cran-pheatmap/ SCR_016418 pretty heatmap 2026-08-06 09:28:49 1068

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