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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
CistromeMap
 
Resource Report
Resource Website
CistromeMap (RRID:SCR_002173) CistromeMap storage service resource, service resource, data repository, data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. A knowledgebase of all of the publicly available ChIP-Seq and DNase-Seq data in mouse and human. They have also manually curated metadata to ensure annotation consistency, and developed a user-friendly display matrix for quick navigation and retrieval of data for specific factors, cells, and papers. The community can contribute to this resource. chip-seq, dnase-seq, cell, factor is listed by: OMICtools
is related to: CistromeFinder
has parent organization: Dana-Farber Cancer Institute
PMID:22495751 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01853 SCR_002173 2026-08-06 09:25:36 0
Current Controlled Trials
 
Resource Report
Resource Website
1000+ mentions
Current Controlled Trials (RRID:SCR_002325) CCT storage service resource, service resource, data repository, data or information resource, database Free-to-view clinical trials register of clinical trials worldwide, it allows users to search, register and share information about randomized controlled trials. Publication services are also available via the range of open access peer-reviewed journals published by BioMed Central. Current Controlled Trials is run by an editorial and technical in-house team. It receives advice from an international Advisory Group, including academics, doctors and health care specialists of international renown. The Advisory Group provides valuable guidance on the current activities and possible new directions of Current Controlled Trials' two databases, the metaRegister of Controlled Trials (mRCT) and the International Standard Randomised Controlled Trial Number (ISRCTN) scheme. controlled trial, health, public health, science, trial, randomized controlled trial, clinical trial, FASEB list uses: ISRCTN Registry
is related to: ISRCTN Registry
is parent organization of: ISRCTN Registry
Science Navigation Group ;
European Union ;
administrative fee
Free and open access nif-0000-21104 http://www.webcitation.org/getfile?fileid=6fc2d850dde348335d1ab0b66828190d475a6967 SCR_002325 Current Controlled Trials Ltd 2026-08-06 09:25:35 1427
Genevestigator
 
Resource Report
Resource Website
100+ mentions
Genevestigator (RRID:SCR_002358) Genevestigator commercial organization, service resource, production service resource, data analysis service, data or information resource, analysis service resource, database A high performance search engine for gene expression that integrates thousands of manually curated public microarray and RNAseq experiments and nicely visualizes gene expression across different biological contexts (diseases, drugs, tissues, cancers, genotypes, etc.). There are two basic analysis approaches: # for a gene of interest, identify which conditions affect its expression. # for condition(s) of interest, identify which genes are specifically expressed in this/these conditions. Genevestigator builds on the deep integration of data, both at the level of data normalization and on the level of sample annotations. This deep integration allows scientists to ask new types of questions that cannot be addressed using conventional tools. gene, genetic, animal, development, disease, meta-analysis, regulation, stage, microarray, rnaseq, visualization, gene expression, disease, drug, tissue, cancer, genotype, pharma, biomedical, conditions, genotype, anatomy, neoplasm, chemical, hormone, infection, model organism, organ, cell type, cell line, target, biomarker, similarity, FASEB list is parent organization of: RefGenes 4 products:, Free, Free for academic use, Account required, Paid subscription, Local installation nif-0000-21172, OMICS_00763 SCR_002358 2026-08-06 09:25:38 396
Cognitive Paradigm Ontology
 
Resource Report
Resource Website
1+ mentions
Cognitive Paradigm Ontology (RRID:SCR_002235) CogPO controlled vocabulary, ontology, data or information resource Ontology used to describe the experimental conditions within cognitive and behavioral experiments, primarily in humans for application and use in the functional neuroimaging community. CogPO has been developed through the integration of the Functional Imaging Biomedical Informatics Research Network (FBIRN) Human Imaging Database (HID) and the BrainMap Database. The design of CogPO concentrates on what can be observed directly: categorization of each paradigm in terms of (1) the stimulus presented to the subjects, (2) the requested instructions, and (3) the returned response. functional neuroimaging, owl, cognition, behavior is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: BioPortal
is related to: Human Imaging Database
has parent organization: University of Texas Health Science Center at San Antonio; Texas; USA
has parent organization: Mind Research Network
NIMH 1R01MH084812-01A1 Free, Freely available nlx_155537 http://www.nitrc.org/projects/cogpo SCR_002235 2026-08-06 09:25:36 9
ROBEX
 
Resource Report
Resource Website
1+ mentions
ROBEX (RRID:SCR_002534) ROBEX software resource, image analysis software, image processing software, segmentation software, data processing software, software application An automatic whole-brain extraction tool for T1-weighted MRI data (commonly known as skull stripping). Whole-brain segmentation is often the first component in neuroimage pipelines and therefore, its robustness is critical for the overall performance of the system. Many methods have been proposed in the literature, but they often: * work well on certain datasets but fail on others. * require case-specific parameter tuning ROBEX aims for robust skull-stripping across datasets with no parameter settings. It fits a triangular mesh, constrained by a shape model, to the probabilistic output of a supervised brain boundary classifier. Because the shape model cannot perfectly accommodate unseen cases, a small free deformation is subsequently allowed. The deformation is optimized using graph cuts. magnetic resonance, mri, skull stripping, classification, segmentation, brain, skull is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) PMID:21880566 Free, Available for download, Freely available nlx_155939 http://www.nitrc.org/projects/robex SCR_002534 Robust Brain Extraction (ROBEX), Robust Brain Extraction 2026-08-06 09:25:39 3
NCANDA: Data Integration Component
 
Resource Report
Resource Website
1+ mentions
NCANDA: Data Integration Component (RRID:SCR_002447) NCANDA-Datacore experimental protocol, software resource, data management, data or information resource, training material, narrative resource Manuals, training materials, and computational tools developed by the National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA) Data Component. The NCANDA consortium consists of an Administrative Component at UC San Diego, the Data Integration Component at SRI International, and five data collection sites, Duke University, Oregon Health & Sciences University, SRI International, University of Pittsburgh, and UC San Diego. Each collection site will collect data from about 150 adolescents, each of them seen for one baseline and three annual follow-up visits. clinical neuroinformatics, computational neuroscience, magnetic resonance, nifti, os independent, data integration, mri, bioinformatics, adolescent, alcohol, neurodevelopment uses: Lightweight Data Pipeline
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Stanford Research Institute International
PMID:26562597
PMID:24296908
Free, Available for download, Freely available nlx_155821 http://ncanda.sri.com SCR_002447 National Consortium on Alcohol and NeuroDevelopment in Adolescence: Data Integration Component 2026-08-06 09:25:40 1
4D-PARSeR Pathological Anatomy Regression via Segmentation and Registration
 
Resource Report
Resource Website
4D-PARSeR Pathological Anatomy Regression via Segmentation and Registration (RRID:SCR_002480) 4D-PARSeR software resource, image analysis software, registration software, data processing software, segmentation software, software application A tool for analyzing 4D images with pathology. Originally developed for processing longitudinal images of patients with traumatic brain injury, the tool contains new image analysis algorithms that combine registration and segmentation in a coherent framework, accounting for extreme changes due to extensive tissue damage. magnetic resonance, registration, segmentation is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Traumatic brain injury Free, Freely avaialble nlx_155870 SCR_002480 4D-PARSeR (Pathological Anatomy Regression via Segmentation and Registration), 4D-Pathological Anatomy Regression via Segmentation and Registration 2026-08-06 09:25:40 0
Cardiovascular Model Repository
 
Resource Report
Resource Website
Cardiovascular Model Repository (RRID:SCR_002679) storage service resource, service resource, data repository, data or information resource, image collection Repository of geometric models collected from on-going and past research projects in the Cardiovascular Biomechanics Research Laboratory at Stanford University. The geometric models are mostly built from imaging data of healthy and diseased individuals. For each of the models, a short description is given with a reference. The geometric models are in VTK PolyData XML .vtp format. * Audience: Biomechanical and computational researchers interested in complex models of cardiovascular applications * Long Term Goals and Related Uses: Allow users to download geometric models for cardiovascular applications. These geometric models can be used for research purposes, such as meshing and scientific visualization. Users are welcome to contact the project administrator, join the project and contribute additional models. aneurysm, arteriofemoral bypass, cardiovascular simulation, image-based geometric modeling, simvascular, stent, vtk, healthy, diseased, normal, cardiovascular, model, cardiovascular model, cardiovascular system, bypass, palmaz-stent, aorta, source code is listed by: Biositemaps
has parent organization: Simtk.org
Normal, Cardiovascular disease, Healthy Free, Available for download, Freely available nif-0000-23301 SCR_002679 2026-08-06 09:25:41 0
HGNC
 
Resource Report
Resource Website
500+ mentions
HGNC (RRID:SCR_002827) controlled vocabulary, database, data or information resource Only worldwide authority that provides standardized nomenclature, i.e. gene names and symbols (short form abbreviations), for all known human genes, and stores all approved symbols in the HGNC database. Approved human gene nomenclature. Database of gene symbols and names. Manually curated genes into groups based on shared characteristics such as homology, function or phenotype. Data for protein-coding genes, pseudogenes and non-coding RNAs. gene, owl, gene symbol, phenotype, nomenclature, gene family, gene groups, genomic, proteomic, ortholog, web service, locus, protein coding, genetics, gold standard, bio.tools, FASEB list, GCBR, ELIXIR Core Data Resource, DRKB is used by: Nowomics
is used by: Cytokine Registry
is listed by: BioPortal
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: Rat Gene Symbol Tracker
is related to: INFEVERS
is related to: VGNC
has parent organization: University of Cambridge School of Clinical Medicine; Cambridge; United Kingdom
NHGRI U24HG003345 PMID:36243972
PMID:32747822
PMID:34615987
PMID:33152070
Free, Freely available biotools:genenames.org, nif-0000-02955, r3d100010901 http://bioportal.bioontology.org/ontologies/HUGO, https://bio.tools/genenames.org, https://doi.org/10.17616/R3XC80 SCR_002827 HUGO symbols, HGNC Database, HGNC - HUGO Gene Nomenclature Committee, HUGO Gene Nomenclature Committee, Human Genome Organization Gene Symbols 2026-08-06 09:25:44 974
UMMC Center for Psychiatric Neuroscience Labs and Facilities
 
Resource Report
Resource Website
UMMC Center for Psychiatric Neuroscience Labs and Facilities (RRID:SCR_002688) UMMC CPN Labs & Facilities, UMMC CPN Labs and Facilities brain bank, tissue bank, material resource, biomaterial supply resource Core facility that provides access to psychiatrically characterized post-mortem brain specimens, state-of-the-art equipment, cutting-edge technologies and the technical advice of highly trained faculty members who serve as Core Directors. The sophisticated imaging systems and biotechnologically advanced molecular core resources are provided on a shared-use basis to CPN and UMMC researchers. The CPN Research Resources Cores include the Human Brain Collection Core, Animal Core, Imaging Core, Molecular Biology Core, and Information Technologies Core. postmortem, brain, tissue, imaging, molecular biology, genomics is listed by: One Mind Biospecimen Bank Listing
is listed by: ScienceExchange
is related to: University of Mississippi Medical Center Labs and Facilities
is related to: University of Mississippi Medical Center Animal Behavior Core Facility
has parent organization: University of Mississippi Medical Center; Mississippi; USA
Depression, Normal, Mental disease NCRR Free SciEx_8930 SCR_002688 CPN Research Resource Cores, University of Mississippi Medical Center Center for Psychiatric Neuroscience, UMMC Center for Psychiatric Neuroscience Research Resource Cores, UMMC Center for Psychiatric Neuroscience Labs & Facilities, UMMC CPN Research Resource Cores 2026-08-06 09:25:42 0
International HapMap Project
 
Resource Report
Resource Website
5000+ mentions
International HapMap Project (RRID:SCR_002846) HapMap database, experimental protocol, narrative resource, data or information resource THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. A multi-country collaboration among scientists and funding agencies to develop a public resource where genetic similarities and differences in human beings are identified and catalogued. Using this information, researchers will be able to find genes that affect health, disease, and individual responses to medications and environmental factors. All of the information generated by the Project will be released into the public domain. Their goal is to compare the genetic sequences of different individuals to identify chromosomal regions where genetic variants are shared. Public and private organizations in six countries are participating in the International HapMap Project. Data generated by the Project can be downloaded with minimal constraints. HapMap project related data, software, and documentation include: bulk data on genotypes, frequencies, LD data, phasing data, allocated SNPs, recombination rates and hotspots, SNP assays, Perlegen amplicons, raw data, inferred genotypes, and mitochondrial and chrY haplogroups; Generic Genome Browser software; protocols and information on assay design, genotyping and other protocols used in the project; and documentation of samples/individuals and the XML format used in the project. genetic variant, disease, genetic sequence, genetic variation, single nucleotide polymorphism, genetic diversity, dna, sequence, catalog, genome, chromosome, bio.tools is used by: BioSample Database at EBI
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: SNAP - SNP Annotation and Proxy Search
is related to: Haploview
is related to: NHGRI Sample Repository for Human Genetic Research
is related to: DistiLD - Diseases and Traits in LD
is related to: SNP at Ethnos
is related to: GBrowse
is related to: Broad Institute Genomics Platform
has parent organization: NCBI
Chinese Academy of Sciences ;
Chinese Ministry of Science and Technology ;
Delores Dore Eccles Foundation ;
Genome Canada ;
Genome Quebec ;
Hong Kong Innovation and Technology Commission ;
Japanese Ministry of Education Culture Sports Science and Technology MEXT ;
National Natural Science Foundation of China ;
SNP Consortium ;
University Grants Committee of Hong Kong ;
Wellcome Trust ;
W. M. Keck Foundation ;
NIH
PMID:14685227 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02940, biotools:int_hapmap_project, r3d100011835, OMICS_00273 http://www.hapmap.org/, https://bio.tools/int_hapmap_project, https://doi.org/10.17616/R3H06Q http://snp.cshl.org SCR_002846 HapMap Project 2026-08-06 09:25:44 6817
HemBase
 
Resource Report
Resource Website
1+ mentions
HemBase (RRID:SCR_002880) resource, database, data or information resource Database designed for web-based examination of the human erythroid transcriptome. The database is organized to provide a cytogenetic band position, a unique name as well as a concise annotation for each entry. Search queries may be performed by name, keyword or cytogenetic location. Search results are linked to primary sequence data and three major human genome browsers for access to information considered current at the time of each search. Hembase provides interested scientists and clinical hematologists with a genome-based approach toward the study of erythroid biology. Red blood cells in the circulation arise from hematopoietic stem cells that proliferate as erythroid progenitors and differentiate into erythroid precursor cells in response to the hormone erythropoietin. Messenger RNA was isolated from those cells and used to generate gene libraries. Sequencing several thousand expressed sequence tags (EST) from those libraries was then performed. Those EST and sequences encoding several hundred additional genes with known expression in erythroid cells are compiled here as a database of human erythroid gene activity. The database is organized and linked according to the location of these sequences within the human genome., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 15,2026. erythroid, erythroid cell, erythroblast, expressed sequenced tag, transcriptome, gene, erythropoiesis, cytogenetic location, hematology, genome, red blood cell, progenitor cell, precursor cell, chromosome is listed by: NIDDK Information Network (dkNET)
is listed by: NIDDK Research Resources
has parent organization: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
Anemia, Erythroleukemia, Malaria, Erythroid cell related disease NIDDK 1ZIADK025098 PMID:14681483
PMID:10409428
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02949 SCR_002880 Hembase 2026-08-06 09:25:44 4
Community Epidemiology Work Group
 
Resource Report
Resource Website
Community Epidemiology Work Group (RRID:SCR_002751) CEWG meeting resource, training resource, report, data or information resource, knowledge environment, book, narrative resource A network composed of researchers from major metropolitan areas of the United States and selected foreign countries which meet semiannually to discuss the current epidemiology of drug abuse. The primary mission of the Work Group is to provide ongoing community-level surveillance of drug abuse through analysis of quantitative and qualitative research data. Through this program the CEWG provides current descriptive and analytical information regarding the nature and patterns of drug abuse, emerging trends, characteristics of vulnerable populations and social and health consequences. Reports Reports are available from the biannual meetings at which the network members discuss current and emerging problems of substance abuse. At the meetings, CEWG members present data on drug abuse from a variety of city, State, Federal, and other sources. These data are enhanced with information gathered through ethnographic research, focus groups, interviews, and other qualitative methods. This integration of quantitative with qualitative data provides invaluable insight into emerging drug use trends. Book In 1998, the National Institute on Drug Abuse (NIDA) published the first edition of Assessing Drug Abuse Within and Across Communities: Community Epidemiology Surveillance Networks on Drug Abuse to share information on establishing drug abuse epidemiology networks at community and State levels. Its purpose is to provide guidelines for establishing epidemiology networks to monitor and assess drug abuse patterns and trends and emerging drug problems at community and State levels to provide a foundation of information for public health response. The second edition differs from the first in format. For each data source, there is a description of the source and database, followed by guidelines on how to access the data (including Web sites) and what to request, and examples of how the data have been used by epidemiology work groups or Federal agencies. NIDA hopes that this revised guide is helpful to agencies, organizations, and researchers that are involved in or wish to establish epidemiology networks in their communities or States. emerging trend, epidemiology, health consequence, social consequence, substance-related disorder, vulnerable population, work group, drug abuse, pattern, trend, characteristic, population, social, health is related to: NIDA Networking Project: Facilitating information exchange and research collaboration
has parent organization: National Institute on Drug Abuse
Drug use disorder NIDA THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-24121 SCR_002751 Community Epidemiology Work Group (CEWG) 2026-08-06 09:25:42 0
NIH NeuroBioBank
 
Resource Report
Resource Website
100+ mentions
NIH NeuroBioBank (RRID:SCR_003131) NBB brain bank, tissue bank, material resource, biomaterial supply resource National resource for investigators utilizing human post-mortem brain tissue and related biospecimens for their research to understand conditions of the nervous system. Federated network of brain and tissue repositories in the United States that collects, evaluates, stores, and makes available to researchers, brain and other tissues in a way that is consistent with the highest ethical and research standards. The NeuroBioBank ensures protection of the privacy and wishes of donors. Provides information to the public about the need for tissue donation and how to register as a donor. human post-mortem brain tissue, human brain, brain tissue, tissue, adult, child, brain donation, human post-mortem brain tissue and related biospecimens, is used by: BRAIN Initiative Cell Atlas Network
is used by: BICCN
is listed by: One Mind Biospecimen Bank Listing
has parent organization: National Institutes of Health
Brain disorder, Autism spectrum disorder, Autism, Major Depressive Disorder, Schizophrenia, Multiple Sclerosis, Epilepsy, Traumatic brain injury NIMH ;
NINDS ;
NICHD ;
NIA ;
NIDA
PMID:29496155 Free, Freely available nlx_156783 SCR_003131 NeuroBioBank, National Institutes of Health NeuroBioBank 2026-08-06 09:25:48 177
Brainscape
 
Resource Report
Resource Website
1+ mentions
Brainscape (RRID:SCR_002962) Brainscape storage service resource, service resource, production service resource, data repository, data analysis service, data or information resource, analysis service resource, image repository, database THIS RESOURCE IS NO LONGER IN SERVICE, documented on May 23, 2013. Database for resting state functional connectivity studies. Functional connectivity has shown tremendous promise in mapping the intrinsic functional topography of the brain, evaluating neuroanatomical models, and investigating neurological and psychiatric disease. Brainscape includes a repository of public and private data and an analysis engine for exploring the correlation structure of spontaneous fluctuations in the fMRI BOLD signal. (DICOM data is the image format that can be uploaded.) With Brainscape you can upload, analyze, and share your own data. You can search for, download, and analyze studies in the repository of shared data. The analysis engine works by selecting one or more studies, typing in the coordinates of a brain region of interest, and the seed-region correlation engine computes the correlation structure across the whole brain. (T1, T2 and EPI data are the scan types Brainscape can process.) You decide who can access your data. You can keep it to yourself, share with select colleagues, or share it with everyone. The Brainscape database and analysis tools are open source and freely available. functional connectivity, fmri bold signal, brain, neuroanatomy, region of interest, resting state, fmri, analysis, processing, dicom, dicom data, t1, t2, epi data, 4-dimensional floating point, raw, statistical comparison, functional topography, neurological, psychiatric, disease, mri, functional, statistical operation, correlation is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Biositemaps
has parent organization: University of California at San Diego; California; USA
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-00501 SCR_002962 2026-08-06 09:25:45 2
CBU Imaging Wiki
 
Resource Report
Resource Website
50+ mentions
CBU Imaging Wiki (RRID:SCR_003014) CBU Imaging Wiki portal, topical portal, data or information resource Portal where neuroimaging studies are carried out using a Siemens 3T Tim Trio Magnetic Resonance Imaging (or MRI) scanner that is wholly dedicated to studies in Cognitive Neuroscience. From emotions and memories to language and learning, functional neuroimaging is being applied in many different areas of Cognitive Neuroscience. In many cases, this research relies upon support from healthy volunteers although neuroimaging studies are also being conducted in various clinical populations, including depression, anxiety, Parkinson's disease and Alzheimer's disease. neuroimaging, cognitive neuroscience, mri, scanner, neuroscience, emotion, memory, language, learning, functional neuroimaging, clinical, population, human, analysis, software, disease, brain, imaging, fmri, cognition is related to: FslAtlasIntegration
has parent organization: MRC Cognition and Brain Sciences Unit
is parent organization of: MNI brain and the Talairach atlas
is parent organization of: MNI brain and the Talairach atlas
Depressive Disorder, Anxiety, Parkinson's disease, Alzheimer's disease MRC THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-30307 SCR_003014 CBUImaging, MRC CBU Imaging Wiki, MRC Cognition and Brain Sciences Unit Imaging Wiki, Cognition and Brain Sciences Unit Imaging Wiki 2026-08-06 09:25:46 58
ADNI - Alzheimer's Disease Neuroimaging Initiative
 
Resource Report
Resource Website
1000+ mentions
ADNI - Alzheimer's Disease Neuroimaging Initiative (RRID:SCR_003007) ADNI storage service resource, service resource, data repository, data or information resource, database Database of the results of the ADNI study. ADNI is an initiative to develop biomarker-based methods to detect and track the progression of Alzheimer's disease (AD) that provides access to qualified scientists to their database of imaging, clinical, genomic, and biomarker data. mri, alzheimer’s disease, cognitive assessment, neuroimaging, disease study, disease progression, biomarker, FASEB list is used by: Biomarkers Across Neurodegenerative Diseases
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Consortia-pedia
is related to: Alzheimers Association
is related to: Alzheimers Drug Discovery Foundation
Alzheimer's disease, Mild Cognitive Impairment, Elderly control, Traumatic brain injury, Post-Traumatic Stress Disorder, Aging NIA U01AG024904;
NIA P30AG010129;
NIA K01AG030514
Application required, Account required, This resource is available to the scientific community SciRes_000144, nif-0000-00516 http://adni.loni.usc.edu/, http://www.nitrc.org/projects/adni/, http://www.adni3.org/ http://www.loni.ucla.edu/ADNI/ SCR_003007 Alzheimers Disease Neuroimaging Initiative, Alzheimer's Disease Neuroimaging Initiative (ADNI), Alzheimer's Disease Neuroimaging Initiative 2026-08-06 09:25:46 3850
DGAP
 
Resource Report
Resource Website
1+ mentions
DGAP (RRID:SCR_003036) DGAP experimental protocol, data or information resource, resource, narrative resource, database Produce resources to unravel the interface between insulin action, insulin resistance and the genetics of type 2 diabetes including an annotated public database, standardized protocols for gene expression and proteomic analysis, and ultimately diabetes-specific and insulin action-specific DNA chips for investigators in the field. The project aims to identify the sets of the genes involved in insulin action and the predisposition to type 2 diabetes, as well as the secondary changes in gene expression that occur in response to the metabolic abnormalities present in diabetes. There are five major and one pilot project involving human and rodent tissues that are designed to: * Create a database of the genes expressed in insulin-responsive tissues, as well as accessible tissues, that are regulated by insulin, insulin resistance and diabetes. * Assess levels and patterns of gene expression in each tissue before and after insulin stimulation in normal and genetically-modified rodents; normal, insulin resistant and diabetic humans, and in cultured and freshly isolated cell models. * Correlate the level and patterns of expression at the mRNA and/or protein level with the genetic and metabolic phenotype of the animal or cell. * Generate genomic sequence from a panel of humans with type 2 diabetes focusing on the genes most highly regulated by insulin and diabetes to determine the range of sequence and expression variation in these genes and the proteins they encode, which might affect the risk of diabetes or insulin resistance. The DGAP project will define: * the normal anatomy of gene expression, i.e. basal levels of expression and response to insulin. * the morbid anatomy of gene expression, i.e., the impact of diabetes on expression patterns and the insulin response. * the extent to which genetic variability might contribute to the alterations in expression or to diabetes itself. gene, insulin action, predisposition, gene expression, metabolic abnormality, diabetes, insulin resistance, genetics, insulin, genetic variation, proteomics, genomics, affymetrix oligonucleotide array, microarray, protein, genomic sequence, data set is related to: NIDDK Information Network (dkNET)
has parent organization: Harvard Medical School; Massachusetts; USA
has parent organization: Broad Institute
has parent organization: Dana-Farber Cancer Institute
has parent organization: University of Massachusetts Medical School; Massachusetts; USA
has parent organization: University of Southern Denmark; Odense; Denmark
Type 2 diabetes, Normal, Insulin resistance NIDDK PMID:19786482 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-30414 SCR_003036 The Diabetes Genome Anatomy Project, Diabetes Genome Anatomy Project 2026-08-06 09:25:47 9
IMGT/HLA
 
Resource Report
Resource Website
100+ mentions
IMGT/HLA (RRID:SCR_002971) IMGT HLA, IMGT/HLA storage service resource, service resource, data repository, data or information resource, database Database for sequences of the human major histocompatibility complex (HLA) and includes the official sequences for the WHO Nomenclature Committee For Factors of the HLA System. It currently contains 9,310 allele sequences (2013) along with detailed information concerning the material from which the sequence was derived and data on the validation of the sequences. It is established procedure for authors to submit the sequences directly to the IMGT/HLA Database for checking and assignment of an official name prior to publication, this avoids the problems associated with renaming published sequences and the confusion of multiple names for the same sequence. The need for reasonably rapid publication of new HLA allele sequences has necessitated an annual meeting of the WHO Nomenclature Committee for Factors of the HLA System. Additionally they now publish monthly HLA nomenclature updates both in journals and online to provide quick and easy access to new sequence information. The IMGT/HLA Database is part of the international ImMunoGeneTics project. In collaboration with the Imperial Cancer Research Fund (ICRF) and European Bioinformatics Institute (EBI) they have developed an Oracle database to house the HLA sequences in such a way as to allow users to present complex queries about the sequence, sequence features, references, contacts and allele designations to the database via a graphical user interface over the web. The IMGT/HLA Database Submission Tool allows direct submission of sequences to the WHO HLA Nomenclature Committee for Factors of the HLA System. The IMGT/HLA Database provides an FTP site for the retrieval of sequences in a number of pre-formatted files. alignment, allele, cell, hla, sequence alignment, major histocompatibility complex, nomenclature, blast, immunogenetics, histocompatibility, gene mapping, gene rearrangement, genetic recombination, genetics, gold standard, bio.tools is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: dbMHC
has parent organization: European Bioinformatics Institute
has parent organization: Anthony Nolan Research Institute
has parent organization: IMGT - the international ImMunoGeneTics information system
EU Biotech grant BIO4CT960037;
Anthony Nolan Trust ;
Imperial Cancer Research Fund
PMID:21071412
PMID:10777106
PMID:18838392
Creative Commons Attribution-NoDerivs License nif-0000-03014, biotools:ipd-imgt_hla, r3d100010804 https://bio.tools/ipd-imgt_hla, https://doi.org/10.17616/R3T31N SCR_002971 IMGT HLA, IMGT/HLA DB, IMGT/HLA Database, International ImMunoGeneTics/Human Leukocyte Antigen Database 2026-08-06 09:25:46 279
Human Mitochondrial Protein Database
 
Resource Report
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1+ mentions
Human Mitochondrial Protein Database (RRID:SCR_002913) HMPDb d spatial image, service resource, production service resource, data analysis service, data or information resource, analysis service resource, database Database of mitochondrial and human nuclear encoded proteins involved in mitochondrial biogenesis and function. This database consolidates information from SwissProt, LocusLink, Protein Data Bank (PDB), GenBank, Genome Database (GDB), Online Mendelian Inheritance in Man (OMIM), Human Mitochondrial Genome Database (mtDB), MITOMAP, Neuromuscular Disease Center and Human 2-D PAGE Databases. The mitochondrion plays a central role in cellular metabolism, and evidence of mitochondrial involvement in a number of different human diseases is increasing. This database is intended as a tool not only to aid in studying the mitochondrion but in studying the associated diseases. Mitochondrial DNA Sequence: A graphical tool was developed to visualize the human mitochondrial DNA sequences that highlight coding regions for RNAs and proteins. Disease susceptible mutations are also noted in the sequence. Mitochondrial DNA Polymorphism: Human mitochondrial sequences of different ethnic groups were obtained from the Human Mitochondrial Genome Database. A DNA sequence analysis tool was developed to compare polymorphisms of different human mitochondrial DNA sequences. This tool allows the user to select mitochondrial sequences from any two human populations and compare them for sequences variations. Mitochondrial proteins related diseases: Malfunction of mitochondrial proteins affect many cells from brain, heart, liver, skeletal muscles, kidney, and the endocrine and the respiratory systems which lead to many diseases. Relevant information for mitochondrial related diseases from OMIM, the Neuromuscular Disease Center and MITOMAP are gathered, and mitochondrion-associated diseases are grouped, categorized, and linked to OMIM. 3-D Structures of Mitochondrial proteins: The available 3D structures for mitochondrial proteins are presented through a custom-made interface. A concise HTML page is generated for reporting the structural details and the associated information obtained from relevant web sites (PDBREPORT, Interatomic Contacts of Structural Units (CSU), PROCHECK, Ligand Protein Contacts (LPC), PROMOTIF and CastP). References are linked to the PubMed site. The 3-D structures are presented through the use of a Kinemage. mitochondrial protein, nuclear protein, mitochondrion, dna sequence, dna polymorphism has parent organization: NIST - National Institute of Standards and Technology THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02969 SCR_002913 Human Mitochondrial Protein Database 2026-08-06 09:25:45 2

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