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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Functional Annotation
 
Resource Report
Resource Website
1+ mentions
Functional Annotation (RRID:SCR_017519) service resource MGI GO project provides functional annotations for mouse gene products using Gene Ontology. Functional annotation using Gene Ontology (GO). MGI, GO, functional, annotation, mouse, gene, product, Gene Ontology uses: Gene Ontology
has parent organization: Mouse Genome Informatics (MGI)
Free, Freely available SCR_017519 2026-08-01 12:06:07 4
Avadis
 
Resource Report
Resource Website
1+ mentions
Rating or validation data
Avadis (RRID:SCR_000644) Avadis software library, software toolkit, software resource Software integrated platform that provides analysis, management and visualization tools for next-generation sequencing data. It supports workflows for RNA-Seq, DNA-Seq, ChIP-Seq and small RNA-Seq experiments. Avadis has a built-in Gene Ontology browser to view ontology hierarchies. There are common ontology paths for multiple genes. Platform has collection of data / text mining algorithms, data visualization libraries, workflow/application automation layers, and enterprise data organization functions. These functions are available as libraries that allow developers to rapidly build software prototypes, applications and off-the-shelf products. The collection of algorithms and visualizations in AVADIS grows as new applications using the platform are developed. Currently, the algorithms that AVADIS platform contains range from general purpose statistical mining and modelling algorithms, to text mining algorithms, to very application-specific algorithms for microarray / NGS data analysis, QSAR modelling and biological networks analysis. AVADIS has a collection of powerful mining algorithms like PCA, ANOVA, T-test, clustering, classification and regression methods. The range of visualizations includes most statistical and data modelling related graphing views, and very application-specific visualizations. Some of the statistical views include 2D/3D scatter plots, profile plots, heat maps, histograms and matrix plot; data modelling relevant views include dendrograms, cluster profiles, similarity images and SOM U-matrices. Application-specific views in AVADIS include pathway network views, genome browsers, chemical structure views and pipe-line views. Platform: Windows compatible, Mac OS X compatible, Linux compatible, pathway network views, genome browsers, chemical structure views, pipe-line views, next-generation sequencing data, integrated platform, view ontology hierarchies, statistical mining and modelling, collection of data, text mining algorithms collection, data visualization libraries, is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01120, nlx_149208 http://www.strandls.com/Avadis SCR_000644 Access Visualize Analyze Discover, Avadis NGS 2026-08-02 09:02:55 2
PhenoM - Phenomics of yeast Mutants
 
Resource Report
Resource Website
PhenoM - Phenomics of yeast Mutants (RRID:SCR_006970) PhenoM image collection, production service resource, data analysis service, service resource, database, analysis service resource, data or information resource Database of morphological phenotypes caused by mutation of essential genes in Saccharomyces cerevisiae, it allows storing, retrieving, visualizing and data mining the quantitative single-cell measurements extracted from micrographs of the temperature-sensitive (ts) mutant cells. PhenoM allows users to rapidly search and retrieve raw images and their quantified morphological data for genes of interest. The database also provides several data-mining tools, including a PhenoBlast module for phenotypic comparison between mutant strains and a Gene Ontology module for functional enrichment analysis of gene sets showing similar morphological alterations. About one-fifth of the genes in the budding yeast are essential for haploid viability and cannot be functionally assessed using standard genetic approaches such as gene deletion. To facilitate genetic analysis of essential genes, we and others have assembled collections of yeast strains expressing temperature-sensitive (ts) alleles of essential genes. To explore the phenotypes caused by essential gene mutation we used a panel of genetically engineered fluorescent markers to explore the morphology of cells in the ts strain collection using high-throughput microscopy. The database contains quantitative measurements of 1,909,914 cells and 78,194 morphological images for 775 temperature-sensitive mutants spanning 491 different essential genes in permissive temperature (26* C) and restrictive temperature (32* C). The morphological images were generated by high-content screening (HCS) technology. phenomics, phenotype, yeast, mutant, cell, morphology, essential gene, gene, high-content screening, microscopy, micrograph, mutant cell, temperature-sensitive allele, allele, genetic analysis, blast, mutation, orf, actin, dna damage, nucleus, mitochondria, plasma membrane, mitotic spindle, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: University of Toronto; Ontario; Canada
Ontario Research Fund ;
Fudan University - University of Toronto Exchange Scholarship ;
Canadian Institutes of Health Research GMX-201237;
Canadian Institutes of Health Research GMX-211012;
Canadian Foundation for Innovation LEF-21475
PMID:22009677 Free nlx_151489, biotools:phenom, r3d100012722 https://bio.tools/phenom, https://doi.org/10.17616/R3GJ5J SCR_006970 Phenomics of yeast Mutants, Phenomics of yeast Mutants (PhenoM) 2026-08-03 09:33:13 0
FunNet - Transcriptional Networks Analysis
 
Resource Report
Resource Website
10+ mentions
FunNet - Transcriptional Networks Analysis (RRID:SCR_006968) FunNet production service resource, data analysis service, software application, data processing software, analysis service resource, service resource, software resource Functional Analysis of Transcriptional Networks (FunNet) is designed as an integrative tool for analyzing gene co-expression networks built from microarray expression data. The analytical model implemented in this tool involves two abstraction layers: transcriptional (i.e. gene expression profiles) and functional (i.e. biological themes indicating the roles of the analyzed transcripts). A functional analysis technique, which relies on Gene Ontology and KEGG annotations, is applied to extract a list of relevant biological themes from microarray gene expression data. Afterwards multiple-instance representations are built to relate relevant biological themes to their annotated transcripts. An original non-linear dynamical model is used to quantify the contextual proximity of relevant genomic themes based on their patterns of propagation in the gene co-expression network (i.e. capturing the similarity of the expression profiles of the transcriptional instances of annotating themes). In the end an unsupervised multiple-instance spectral clustering procedure is used to explore the modular architecture of the co-expression network by grouping together biological themes demonstrating a significant relationship in the co-expression network. Functional and transcriptional representations of the co-expression network are provided, together with detailed information on the contextual centrality of related transcripts and genomic themes. FunNet is provided both as a web-based tool and as a standalone R package. The standalone R implementation can be run on any operating system for which an R environment implementation is available (Windows, Mac OS, various flavors of Linux and Unix) and can be downloaded from the FunNet website, or from the worldwide mirrors of CRAN. Both implementations of the FunNet tool are provided freely under the GNU General Public License 2.0. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible genome, transcriptional interaction, microarray, gene expression, statistical analysis is listed by: Gene Ontology Tools
is related to: Gene Ontology
is related to: KEGG
has parent organization: Cordelier Research Center
PMID:18208606 Free for academic use, GNU General Public License, v2 nlx_149243 SCR_006968 Functional Analysis of Transcriptional Networks, Functional Analysis of Transcriptional Networks (FunNet) 2026-08-03 09:33:14 16
GOblet
 
Resource Report
Resource Website
1+ mentions
GOblet (RRID:SCR_006998) GOblet production service resource, data analysis service, software application, analysis service resource, service resource, software resource Tool that performs annotation based on GO and pathway terms for anonymous cDNA or protein sequences. It uses the species independent GO structure and vocabulary together with a series of protein databases collected from various sites, to perform a detailed GO annotation by sequence similarity searches. The sensitivity and the reference protein sets can be selected by the user. GOblet runs automatically and is available as a public service on our web server. GOblet expects query sequences to be in FASTA-Format (with header-lines). Protein and nucleotide sequences are accepted. Total size of all sequences submitted per request should not be larger than 50kb currently. For security reasons: Larger post's will be rejected. Due to limited capacities the queries may be processed in batches depending on the server load. The output of the BLAST job is filtered automatically and the relevant hits are displayed. In addition, the respective GO-terms are shown together with the complete GO-hierarchy of parent terms., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, sequence, cdna, ontology or annotation browser, pathway, term enrichment, clustering, virus, genomic, protein, nucleotide is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
has parent organization: Max Planck Institute for Molecular Genetics; Berlin; Germany
BMBF PMID:20134064
PMID:15215401
PMID:12824400
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-30624, OMICS_02271 http://goblet.molgen.mpg.de SCR_006998 2026-08-03 09:33:15 6
agriGO
 
Resource Report
Resource Website
1000+ mentions
agriGO (RRID:SCR_006989) agriGO production service resource, data analysis service, data or information resource, database, analysis service resource, service resource A web-based tool and database for the gene ontology analysis. Its focus is on agricultural species and is user-friendly. The agriGO is designed to provide deep support to agricultural community in the realm of ontology analysis. Compared to other available GO analysis tools, unique advantages and features of agriGO are: # The agriGO especially focuses on agricultural species. It supports 45 species and 292 datatypes currently. And agriGO is designed as an user-friendly web server. # New tools including PAGE (Parametric Analysis of Gene set Enrichment), BLAST4ID (Transfer IDs by BLAST) and SEACOMPARE (Cross comparison of SEA) were developed. The arrival of these tools provides users with possibilities for data mining and systematic result exploration and will allow better data analysis and interpretation. # The exploratory capability and result visualization are enhanced. Results are provided in different formats: HTML tables, tabulated text files, hierarchical tree graphs, and flash bar graphs. # In agriGO, PAGE and SEACOMPARE can be used to carry out cross-comparisons of results derived from different data sets, which is very important when studying multiple groups of experiments, such as in time-course research. Platform: Online tool, THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. browser, gene, online tool, visualization, statistical analysis, term enrichment, text mining, ontology or annotation browser, ontology or annotation visualization, database or data warehouse, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: China Agricultural University; Beijing; China
Ministry of Science and Technology of China 90817006;
Ministry of Science and Technology of China 2006CB100105
PMID:20435677 THIS RESOURCE IS NO LONGER IN SERVICE nlx_149099, OMICS_02265, biotools:agrigo https://bio.tools/agrigo SCR_006989 agriGO -- GO Analysis Toolkit and Database for Agricultural Community 2026-08-03 09:33:15 1716
YeTFaSCo
 
Resource Report
Resource Website
10+ mentions
YeTFaSCo (RRID:SCR_006893) YeTFaSCo data repository, production service resource, data analysis service, service resource, database, storage service resource, analysis service resource, data or information resource Collection of all available transcription factor (TF) specificities for the yeast Saccharomyces cerevisiae in Position Frequency Matrix (PFM) or Position Weight Matrix (PWM) formats. The specificities are evaluated for quality using several metrics. With this website, you can scan sequences with the motifs to find where potential binding sites lie, inspect precomputed genome-wide binding sites, find which TFs have similar motifs to one you have found, and download the collection of motifs. Submissions are welcome. transcription factor, binding site, sequence, yeast, motif, gene, genome, protein, protein complex is listed by: OMICtools
is related to: Gene Ontology
has parent organization: University of Toronto; Ontario; Canada
Ontario Graduate Scholarship awards ;
Canadian Institutes of Health Research Operating Grant MOP-490425;
Canadian Institutes of Health Research Operating Grant MOP-86705
PMID:22102575 Acknowledgement requested nlx_151611, OMICS_01861 SCR_006893 Yeast Transcription Factor Specificity Compendium, YeTFaSCo: The Yeast Transcription Factor Specificity Compendium 2026-08-03 09:33:12 34
OBO
 
Resource Report
Resource Website
100+ mentions
OBO (RRID:SCR_007083) OBO knowledge environment, standard specification, ontology, narrative resource, controlled vocabulary, data or information resource A collaboration involving developers of science-based ontologies who are establishing a set of principles for ontology development with the goal of creating a suite of orthogonal interoperable reference ontologies in the biomedical domain. In addition to a listing of OBO ontologies, this site provides a statement of the OBO Foundry principles, discussion fora, technical infrastructure, and other services to facilitate ontology development. Feedback is welcome and participation encouraged. biomedical, metadata standard, gold standard, FASEB list lists: CHEBI
lists: NCI Thesaurus
lists: Porifera Ontology
lists: Gazetteer
lists: Human Disease Ontology
lists: Information Artifact Ontology
lists: Teleost Anatomy Ontology
lists: Gene Ontology
lists: Spider Ontology
lists: Mental Functioning Ontology
lists: Ascomycete Phenotype Ontology
lists: Beta Cell Genomics Ontology
lists: Biological Collections Ontology
lists: Emotion Ontology
lists: Chemical Methods Ontology
lists: Chemical Information Ontology
lists: Clinical Measurement Ontology
lists: Common Anatomy Reference Ontology
lists: Experimental Conditions Ontology
lists: Dictyostelium Discoideum Anatomy Ontology
lists: Fission Yeast Phenotype Ontology
lists: Fly Taxonomy
lists: FlyBase Controlled Vocabulary
lists: Hymenoptera Anatomy Ontology
lists: Influenza Ontology
lists: Lipid Ontology
lists: Kinetic Simulation Algorithm Ontology
lists: Malaria Ontology
lists: Measurement Method Ontology
lists: Minimal Anatomical Terminology
lists: Ontology for Genetic Interval
lists: Ontology for Parasite LifeCycle
lists: Ontology of Adverse Events
lists: Ontology of Medically Related Social Entities
lists: Ontology of Vaccine Adverse Events
lists: Rat Strain Ontology
lists: Plant Environmental Conditions
lists: Plant Trait Ontology
lists: Population and Community Ontology
lists: RNA Ontology
lists: Rat Strain Ontology
lists: Subcellular Anatomy Ontology
lists: Software Ontology
lists: Suggested Ontology for Pharmacogenomics
lists: Vertebrate Taxonomy Ontology
lists: Physico-Chemical Process
lists: Adverse Event Reporting Ontology
lists: Xenopus Anatomy Ontology
lists: Cell Line Ontology
lists: Human Phenotype Ontology
lists: Neurobehavior Ontology
lists: Ontology for Biomedical Investigations
lists: Comparative Data Analysis Ontology
lists: Ontology for General Medical Science
lists: Physico-Chemical Methods and Properties
lists: Gene Regulation Ontology
is listed by: FORCE11
is related to: MeGO
is related to: Drosophila anatomy and development ontologies
is related to: Cell Type Ontology
is related to: OBO-Edit
is related to: go-perl
is related to: OWLTools
is related to: Zebrafish Anatomical Ontology
is related to: OBO Tracker: Plant Ontology (PO) TERM requests
is related to: eVOC
is related to: OnEx - Ontology Evolution Explorer
is related to: BioPerl
is related to: dkCOIN
is related to: Standards-based Infrastructure with Distributed Resources
is related to: OntoVisT
is related to: COBrA
is related to: Wandora
is related to: ONTO-PERL
is related to: Genomic Standards Consortium
is related to: Ontology Lookup Service
is related to: LexGrid
is related to: SBO
is related to: RIKEN integrated database of mammals
is related to: DOAF
is related to: Gene Ontology
is related to: African Population Ontology
has parent organization: Berkeley Bioinformatics Open-Source Projects
is parent organization of: OBO Relation Ontology
is parent organization of: SO
is parent organization of: PATO
is parent organization of: MPO
is parent organization of: AEO
is parent organization of: UBERON
PMID:17989687 nlx_22892 SCR_007083 The Open Biomedical Ontologies, OBO Foundry, Open Biological and Biomedical Ontologies, Open Biological and Biomedical Ontology Foundry 2026-08-03 09:33:21 169
Organelle DB
 
Resource Report
Resource Website
1+ mentions
Organelle DB (RRID:SCR_007837) Organelle DB image collection, data repository, d spatial image, data or information resource, database, storage service resource, service resource Database of organelle proteins, and subcellular structures / complexes from compiled protein localization data from organisms spanning the eukaryotic kingdom. All data may be downloaded as a tab-delimited text file and new localization data (and localization images, etc) for any organism relevant to the data sets currently contained in Organelle DB is welcomed. The data sets in Organelle DB encompass 138 organisms with emphasis on the major model systems: S. cerevisiae, A. thaliana, D. melanogaster, C. elegans, M. musculus, and human proteins as well. In particular, Organelle DB is a central repository of yeast protein localization data, incorporating results from both previous and current (ongoing) large-scale studies of protein localization in Saccharomyces cerevisiae. In addition, we have manually curated several recent subcellular proteomic studies for incorporation in Organelle DB. In total, Organelle DB is a singular resource consolidating our knowledge of the protein composition of eukaryotic organelles and subcellular structures. When available, we have included terms from the Gene Ontologies: the cellular component, molecular function, and biological process fields are discussed more fully in GO. Additionally, when available, we have included fluorescent micrographs (principally of yeast cells) visualizing the described protein localization. Organelle View is a visualization tool for yeast protein localization. It is a visually engaging way for high school and undergraduate students to learn about genetics or for visually-inclined researchers to explore Organelle DB. By revealing the data through a colorful, dimensional model, we believe that different kinds of information will come to light. gene, fly, vertebrate, human, mouse, plant, worm, yeast, protein, k-12, organelle, protein localization, function, subcellular structure, protein complex, sequence, annotation, micrograph, visualization, data analysis service is related to: Gene Ontology
has parent organization: University of Michigan; Ann Arbor; USA
American Cancer Society Research Scholar Grant RSG-06-179-01-MBC;
March of Dimes Basil O'Connor Starter Scholar Research award 5-FY05-1224;
NSF DBI-0543017
PMID:17130152
PMID:15608270
Free, Acknowledgement requested nif-0000-03226 SCR_007837 Organelle DB: A Database of Organelles and Protein Complexes 2026-08-03 09:33:33 7
Network Analysis, Visualization and Graphing TORonto
 
Resource Report
Resource Website
50+ mentions
Network Analysis, Visualization and Graphing TORonto (RRID:SCR_008373) NAViGaTOR software application, data processing software, d visualization software, software resource, data visualization software A software package for visualizing and analyzing protein-protein interaction networks. NAViGaTOR can query OPHID / I2D - online databases of interaction data - and display networks in 2D or 3D. To improve scalability and performance, NAViGaTOR combines Java with OpenGL to provide a 2D/3D visualization system on multiple hardware platforms. NAViGaTOR also provides analytical capabilities and supports standard import and export formats such as GO and the Proteomics Standards Initiative (PSI). NAViGaTOR can be installed and run on Microsoft Windows, Linux / UNIX, and Mac OS systems. NAViGaTOR is written in Java and uses JOGL (Java bindings for OpenGL) to support scalability, highlighting or suppressing of information, and other advanced graphic approaches. fly, algorithm, capacity, graphical, graphing, human, interaction, interactome, intersection, mouse, network, node, protein, proteomic, rat, worm, yeast, graphing application, 2d visualization, 3d visualization, visualization, biological network, protein-protein interaction, gene, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: University of Toronto; Ontario; Canada
Genome Canada ;
Ontario Genomics Institute ;
Canada Research Chair Program ;
Ontario Research Fund Research Excellence ;
Canada Foundation for Innovation 12301;
Canada Foundation for Innovation 203383
PMID:19837718 Freely-downloadable for academic and not-for-profit institutions nif-0000-25610, biotools:navigator https://bio.tools/navigator SCR_008373 NAViGaTOR - Network Analysis Visualization and Graphing TORonto, NAViGaTOR - Network Analysis Visualization & Graphing TORonto 2026-08-03 09:34:01 52
OnEx - Ontology Evolution Explorer
 
Resource Report
Resource Website
1+ mentions
OnEx - Ontology Evolution Explorer (RRID:SCR_000602) OnEx software resource, web application THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 6,2023. Web-based application that integrates versions of 16 life science ontologies including the Gene Ontology, NCI Thesaurus and selected OBO ontologies with data leading back to 2002 in a common repository to explore ontology changes. It allows to study and apply the evolution of these integrated ontologies on three different levels. It provides global ontology evolution statistics and ontology-specific evolution trends for concepts and relationships and it allows the migration of annotations in case a new ontology version was released ontology, gene, protein, function, process, component, ontology or annotation browser, evolution, trend, annotation, version is listed by: OMICtools
is listed by: Gene Ontology Tools
is related to: Gene Ontology
is related to: NCI Thesaurus
is related to: OBO
has parent organization: University of Leipzig; Saxony; Germany
BMBF 01AK803E;
DFG
PMID:19678926 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02273, nlx_149129 http://www.izbi.de/onex, http://aprilia.izbi.uni-leipzig.de:8080/onex/ SCR_000602 Ontology Evolution Explorer (OnEx), Ontology Evolution Explorer 2026-08-03 09:31:06 1
categoryCompare
 
Resource Report
Resource Website
1+ mentions
categoryCompare (RRID:SCR_001223) categoryCompare software resource, data processing software, software application, data analysis software A software package for meta-analysis of high-throughput experiments using feature annotations. It calculates significant annotations (categories) in each of two (or more) feature (i.e. gene) lists, determines the overlap between the annotations, and returns graphical and tabular data about the significant annotations and which combinations of feature lists the annotations were found to be significant. Interactive exploration is facilitated through the use of RCytoscape (heavily suggested). annotation, go, gene expression, multiple comparison, pathway, gene uses: Cytoscape
is listed by: OMICtools
is related to: Gene Ontology
is related to: CRAN
has parent organization: Bioconductor
PMID:24808906 Free, Available for download, Freely available OMICS_02122 SCR_001223 categoryCompare - Meta-analysis of high-throughput experiments using feature annotations 2026-08-03 09:31:19 9
globaltest
 
Resource Report
Resource Website
10+ mentions
globaltest (RRID:SCR_001256) globaltest sequence analysis software, software application, data processing software, data analysis software, software resource A software package that tests groups of covariates (or features) for association with a response variable. The package implements the test with diagnostic plots and multiple testing utilities, along with several functions to facilitate the use of this test for gene set testing of GO and KEGG terms. differential expression, go, microarray, one channel, pathway, bio.tools uses: KEGG
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: Bioconductor
PMID:34046931 Free, Available for download, Freely available biotools:globaltest, OMICS_02084 https://bio.tools/globaltest SCR_001256 2026-08-03 09:31:16 30
CELDA Ontology
 
Resource Report
Resource Website
CELDA Ontology (RRID:SCR_001601) CELDA controlled vocabulary, data or information resource, ontology Structured vocabulary to organize cell-associated data and to place these data in clearly defined semantic relations to other biological facts. It describes cell types, their properties and origin and links this information to other existing ontologies like the Cell Ontology (CL), Foundational Model of Anatomy (FMA), Gene Ontology (GO), Mouse Anatomy and others using the top-level ontology BioTop. cell, expression, localization, development, anatomy, cell type, development, organ, kidney, liver, skin is related to: Cell Type Ontology
is related to: FMA
is related to: Gene Ontology
has parent organization: CellFinder
Seoul National University; Seoul; South Korea ;
Research Institute for Veterinary Science ;
DFG KU 851/3-1;
DFG LE 1428/3-1;
DFG JA 1904/2-1
PMID:23865855 THIS RESOURCE IS NO LONGER IN SERVICE nlx_153858 SCR_001601 Cell: Expression Localization Development Anatomy, CellFinder Ontology, CELDA Ontology 2026-08-03 09:31:25 0
MatrixDB
 
Resource Report
Resource Website
50+ mentions
MatrixDB (RRID:SCR_001727) MatrixDB service resource, data or information resource, database, production service resource Freely available database focused on interactions established by extracellular proteins and polysaccharides, taking into account the multimeric nature of the extracellular proteins (e.g. collagens, laminins and thrombospondins are multimers). MatrixDB is an active member of the International Molecular Exchange (IMEx) consortium and has adopted the PSI-MI standards for annotating and exchanging interaction data. It includes interaction data extracted from the literature by manual curation, and offers access to relevant data involving extracellular proteins provided by the IMEx partner databases through the PSICQUIC webservice, as well as data from the Human Protein Reference Database. The database reports mammalian protein-protein and protein-carbohydrate interactions involving extracellular molecules. Interactions with lipids and cations are also reported. MatrixDB is focused on mammalian interactions, but aims to integrate interaction datasets of model organisms when available. MatrixDB provides direct links to databases recapitulating mutations in genes encoding extracellular proteins, to UniGene and to the Human Protein Atlas that shows expression and localization of proteins in a large variety of normal human tissues and cells. MatrixDB allows researchers to perform customized queries and to build tissue- and disease-specific interaction networks that can be visualized and analyzed with Cytoscape or Medusa. Statistics (2013): 2283 extracellular matrix interactions including 2095 protein-protein and 169 protein-glycosaminoglycan interactions. extracellular, protein fragment, biomolecule, cation, cleavage, collagen, glycosaminoglycan, human, interaction, laminin, lipid, mammalian, matricryptin, matrikin, matrix, molecule, monomer, mulimerization, multimer, polysaccharide, protein, protein-carbohydrate interaction, protein-protein interaction, recognition, thrombospondin, interactome, extracellular protein, protein-polysaccharide interaction, extracellular interaction, molecular interaction, model organism, inorganic, small molecule-protein, small molecule, extracellular matrix protein, protein-glycosaminoglycan interaction, bio.tools, FASEB list is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: IMEx - The International Molecular Exchange Consortium
is related to: Gene Ontology
is related to: PSI-MI
is related to: HPRD - Human Protein Reference Database
is related to: Interaction Reference Index
is related to: ConsensusPathDB
is related to: IMEx - The International Molecular Exchange Consortium
is related to: PSICQUIC Registry
is related to: IntAct
has parent organization: Claude Bernard University Lyon 1; Lyon; France
European Union contract FP7-HEALTH-2007-223411 PMID:20852260
PMID:19147664
THIS RESOURCE IS NO LONGER IN SERVICE biotools:matrixdb, r3d100010672, nif-0000-10226 https://bio.tools/matrixdb, https://doi.org/10.17616/R3M03H http://matrixdb.ibcp.fr/ SCR_001727 MatrixDB: Extracellular Matrix Interactions Database, Extracellular Matrix Interactions Database 2026-08-03 09:31:25 86
Kidney and Urinary Pathway Knowledge Base
 
Resource Report
Resource Website
1+ mentions
Kidney and Urinary Pathway Knowledge Base (RRID:SCR_001746) KUPKB data repository, production service resource, data analysis service, service resource, storage service resource, analysis service resource, data or information resource, data set A collection of omics datasets (mRNA, proteins and miRNA) that have been extracted from PubMed and other related renal databases, all related to kidney physiology and pathology giving KUP biologists the means to ask queries across many resources in order to aggregate knowledge that is necessary for answering biological questions. Some microarray raw datasets have also been downloaded from the Gene Expression Omnibus and analyzed by the open-source software GeneArmada. The Semantic Web technologies, together with the background knowledge from the domain's ontologies, allows both rapid conversion and integration of this knowledge base. SPARQL endpoint http://sparql.kupkb.org/sparql The KUPKB Network Explorer will help you visualize the relationships among molecules stored in the KUPKB. A simple spreadsheet template is available for users to submit data to the KUPKB. It aims to capture a minimal amount of information about the experiment and the observations made. kidney, urinary, urine, pathway, molecule, visualizer, gene, protein, mirna, metabolite, mrna, microarray, ortholog, rdf, renal cell, anatomy, animal model, disease, sparql, proteomics, ontology, biomarker, gene expression, physiology, pathology is related to: NIDDK Information Network (dkNET)
is related to: Gene Expression Omnibus
is related to: Gene Ontology
is related to: KEGG
has parent organization: University of Manchester; Manchester; United Kingdom
has parent organization: National Institute of Health and Medical Research; Rennes; France
Kidney disease European Union ;
FP7 ;
ICT-2007.4.4 e-LICO project
PMID:21624162 THIS RESOURCE IS NO LONGER IN SERVICE. nlx_154134 http://www.e-lico.eu/kupkb SCR_001746 Kidney & Urinary Pathway Knowledge Base 2026-08-03 09:31:29 2
MouseCyc
 
Resource Report
Resource Website
1+ mentions
MouseCyc (RRID:SCR_001791) MouseCyc production service resource, data analysis service, service resource, database, analysis service resource, data or information resource A manually curated database of both known and predicted metabolic pathways for the laboratory mouse. It has been integrated with genetic and genomic data for the laboratory mouse available from the Mouse Genome Informatics database and with pathway data from other organisms, including human. The database records for 1,060 genes in Mouse Genome Informatics (MGI) are linked directly to 294 pathways with 1,790 compounds and 1,122 enzymatic reactions in MouseCyc. (Aug. 2013) BLAST and other tools are available. The initial focus for the development of MouseCyc is on metabolism and includes such cell level processes as biosynthesis, degradation, energy production, and detoxification. MouseCyc differs from existing pathway databases and software tools because of the extent to which the pathway information in MouseCyc is integrated with the wealth of biological knowledge for the laboratory mouse that is available from the Mouse Genome Informatics (MGI) database. energy production, biosynthesis, cell, cellular, degradation, detoxification, metabolism, mouse, physiological, enzymatic reaction, gene, disease, genome, metabolic pathway, pathway, compound, enzymatic reaction, protein, rna, reaction, blast, human, mammal, genetic, genomic is related to: Mouse Genome Informatics (MGI)
is related to: Gene Ontology
has parent organization: Jackson Laboratory
NHGRI HG003622 PMID:19682380 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-10303 SCR_001791 MouseCyc database, Mouse Genome Informatics: MouseCyc database 2026-08-03 09:31:30 9
Arabidopsis Hormone Database
 
Resource Report
Resource Website
10+ mentions
Arabidopsis Hormone Database (RRID:SCR_001792) AHD, AHD2.0 data repository, ontology, service resource, database, storage service resource, controlled vocabulary, data or information resource Database providing a systematic and comprehensive view of morphological phenotypes regulated by plant hormones, as well as regulatory genes participating in numerous plant hormone responses. By integrating the data from mutant studies, transgenic analysis and gene ontology annotation, genes related to the stimulus of eight plant hormones were identified, including abscisic acid, auxin, brassinosteroid, cytokinin, ethylene, gibberellin, jasmonic acid and salicylic acid. Another pronounced characteristics of this database is that a phenotype ontology was developed to precisely describe all kinds of morphological processes regulated by plant hormones with standardized vocabularies. To increase the coverage of phytohormone related genes, the database has been updated from AHD to AHD2.0 adding and integrating several pronounced features: (1) added 291 newly published Arabidopsis hormone related genes as well as corrected information (e.g. the arguable ABA receptors) based on the recent 2-year literature; (2) integrated orthologues of sequenced plants in OrthoMCLDB into each gene in the database; (3) integrated predicted miRNA splicing site in each gene in the database; (4) provided genetic relationship of these phytohormone related genes mining from literature, which represents the first effort to construct a relatively comprehensive and complex network of hormone related genes as shown in the home page of our database; (5) In convenience to in-time bioinformatics analysis, they also provided links to a powerful online analysis platform Weblab that they have recently developed, which will allow users to readily perform various sequence analysis with these phytohormone related genes retrieved from AHD2.0; (6) provided links to other protein databases as well as more expression profiling information that would facilitate users for a more systematic analysis related to phytohormone research. Please help to improve the database with your contributions. arabidopsis thaliana, hormone, hormone function, hormone gene, phytohormone, abscisic acid, auxin, brassinosteroid, cytokinin, ethylene, gibberellin, jasmonic acid, salicylic acid, microarray, phenotype, gene, mirna prediction, expression, mutant, blast, orthologue, mirna splicing site, root, cotyledon, leaf, hypocotyl, stem, flower, silique, seed, embryo, stress, morphology, plant, hormone, regulatory gene, mutant, transgenic, annotation, data analysis service is related to: Gene Ontology
has parent organization: Peking University; Beijing; China
National Natural Science Foundation of China 30625003;
National Natural Science Foundation of China 30730011;
Ministry of Science and Technology of China 2009CB119101;
Ministry of Education of China ED20060047
PMID:21045062
PMID:19015126
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02559 SCR_001792 Arabidopsis Hormone Database 2.0 2026-08-03 09:31:26 28
Diabetes Disease Portal
 
Resource Report
Resource Website
Diabetes Disease Portal (RRID:SCR_001660) Diabetes Disease Portal portal, disease-related portal, topical portal, data or information resource, data set An integrated resource for information on genes, QTLs and strains associated with diabetes. The portal provides easy acces to data related to both Type 1 and Type 2 Diabetes and Diabetes-related Obesity and Hypertension, as well as information on Diabetic Complications. View the results for all the included diabetes-related disease states or choose a disease category to get a pull-down list of diseases. A single click on a disease will provide a list of related genes, QTLs, and strains as well as a genome wide view of these via the GViewer tool. A link from GViewer to GBrowse shows the genes and QTLs within their genomic context. Additional pages for Phenotypes, Pathways and Biological Processes provide one-click access to data related to diabetes. Tools, Related Links and Rat Strain Models pages link to additional resources of interest to diabetes researchers. gene, quantitative trait locus, strain, diabetic complication, genome, gviewer, genomic, phenotype, pathway, biological process, chromosome, visualization, molecular function, cellular component, synteny is related to: NIDDK Information Network (dkNET)
is related to: Gene Ontology
has parent organization: Rat Genome Database (RGD)
Type 1 diabetes, Type 2 diabetes, Diabetes, Obesity, Hyperlipidemia, Metaboic disease, Hypertension Free, Freely Available nlx_153942 http://rgd.mcw.edu/rgdCuration/?module=portal&func=show&name=diabetes SCR_001660 2026-08-03 09:31:27 0
Candida Genome Database
 
Resource Report
Resource Website
100+ mentions
Candida Genome Database (RRID:SCR_002036) CGD, CGD LOCUS, CGD REF data repository, data or information resource, database, storage service resource, service resource Database of genetic and molecular biological information about Candida albicans. Contains information about genes and proteins, descriptions and classifications of their biological roles, molecular functions, and subcellular localizations, gene, protein, and chromosome sequence information, tools for analysis and comparison of sequences and links to literature information. Each CGD gene or open reading frame has an individual Locus Page. Genetic loci that are not tied to DNA sequence also have Locus Pages. Provides Gene Ontology, GO, to all its users. Three ontologies that comprise GO (Molecular Function, Cellular Component, and Biological Process) are used by multiple databases to annotate gene products, so that this common vocabulary can be used to compare gene products across species. Development of ontologies is ongoing in order to incorporate new information. Data submissions are welcome. protein, chromosome, classification, gene, genome, candidiasis, thrush, yeast, yeast gene, yeast genome, candida albicans, candida glabrata, data analysis service, biological role, molecular function, subcellular localization, chromosome sequence, bio.tools, FASEB list is used by: NIF Data Federation
is listed by: bio.tools
is listed by: Debian
is related to: AmiGO
is related to: ASPGD
is related to: Gene Ontology
has parent organization: Stanford University School of Medicine; California; USA
NIDCR DE015873 PMID:19808938 Free, Available for download, Freely available nif-0000-02634, biotools:cgd, r3d100010617 https://bio.tools/cgd SCR_002036 2026-08-03 09:31:31 472

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