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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
KisSplice
 
Resource Report
Resource Website
10+ mentions
KisSplice (RRID:SCR_011893) KisSplice software resource, data processing software, software application, data analysis software Software tool that enables analysis of RNA-seq data with or without reference genome. Local transcriptome assembler for SNPs, indels and AS events. RNA-seq data analysis, with reference genome, without reference genome, local transcriptome assembler, SNPs, indels, AS events., bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
DOI:10.1186/1471-2105-13-S6-S5 Free, Available for download, Freely available biotools:KisSplice, OMICS_01321 https://bio.tools/KisSplice, https://sources.debian.org/src/kissplice/ SCR_011893 2026-08-05 10:45:37 20
ECHO
 
Resource Report
Resource Website
100+ mentions
ECHO (RRID:SCR_011851) ECHO data processing software, algorithm resource, software application, data analysis software, sequence analysis software, software resource Error correction algorithm designed for short-reads from next-generation sequencing platforms such as Illumina''s Genome Analyzer II. error correction, rnaseq, rna sequence, short-read, next-generation sequencing, ngs, illumina, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21482625
DOI:10.1101/gr.111351.110
Free, Available for download biotools:echo, OMICS_01102 https://bio.tools/echo, https://sources.debian.org/src/uc-echo/ SCR_011851 ECHO: A reference-free short-read error correction algorithm 2026-08-05 10:45:37 310
CANGS
 
Resource Report
Resource Website
1+ mentions
CANGS (RRID:SCR_011837) CANGS software resource, data processing software, software application, data analysis software A user-friendly utility for processing and analyzing 454 GS-FLX data in biodiversity studies. windows, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
PMID:20180949 biotools:cangs, OMICS_01084 https://bio.tools/cangs SCR_011837 2026-08-05 10:45:37 1
JiffyNet
 
Resource Report
Resource Website
1+ mentions
JiffyNet (RRID:SCR_011954) software application, simulation software, software resource, data analysis service, production service resource, service resource, analysis service resource Web based instant protein network modeler for newly sequenced species. Web server designed to instantly construct genome scale protein networks using protein sequence data. Provides network visualization, analysis pages and solution for instant network modeling of newly sequenced species. protein network, protein, network, genome, sequence, pathway annotation, network visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Yonsei University; Seoul; South Korea
National Research Foundation of Korea ;
Next-Generation BioGreen 21 Program
PMID:23685435 Free, Freely available OMICS_01548, biotools:jiffynet https://bio.tools/jiffynet SCR_011954 2026-08-05 10:45:38 1
sabre
 
Resource Report
Resource Website
100+ mentions
sabre (RRID:SCR_011843) sabre software resource, data processing software, software application, data analysis software Software tool to demultiplex barcoded reads into separate files. Works on both single-end and paired-end data in fastq format. Used in next generation sequencing to analyze a broad range of data. demultiplex, bardcode, separate, fastq, format, data, next, generation, sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:sabre, OMICS_01090 https://bio.tools/sabre SCR_011843 Systems Approach to Biomarker Research 2026-08-05 10:45:37 199
NGSmethDB
 
Resource Report
Resource Website
1+ mentions
NGSmethDB (RRID:SCR_012847) NGSmethDB data or information resource, data repository, database, storage service resource, service resource A dedicated database for the storage, browsing and data mining of whole-genome, single-base-pair resolution methylomes. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:20965971 OMICS_01844, biotools:ngsmethdb https://bio.tools/ngsmethdb SCR_012847 NGSmethDB - A database for NGS single-cytosine-resolution DNA methylation data 2026-08-05 10:45:53 9
TopHat
 
Resource Report
Resource Website
5000+ mentions
Rating or validation data
TopHat (RRID:SCR_013035) data processing software, software application, image analysis software, alignment software, data analysis software, sequence analysis software, software resource Software tool for fast and high throughput alignment of shotgun cDNA sequencing reads generated by transcriptomics technologies. Fast splice junction mapper for RNA-Seq reads. Aligns RNA-Seq reads to mammalian-sized genomes using ultra high-throughput short read aligner Bowtie, and then analyzes mapping results to identify splice junctions between exons.TopHat2 is accurate alignment of transcriptomes in presence of insertions, deletions and gene fusions. align, RNA-Seq, read, cDNA, sequencing, transcriptomics, fast, splice, junction, mapper, exon, analysis, bio.tools uses: Bowtie
is used by: CIRCexplorer
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: HISAT2
has parent organization: University of Maryland; Maryland; USA
has parent organization: University of California at Berkeley; Berkeley; USA
has parent organization: Johns Hopkins University; Maryland; USA
has parent organization: University of Washington; Seattle; USA
works with: GeneScissors
NHGRI R01 HG006102;
NHGRI R01 HG006677
PMID:23618408
PMID:19289445
DOI:10.1093/bioinformatics/btp120
Free, Available for download, Freely available biotools:tophat, OMICS_01257 https://github.com/infphilo/tophat, https://bio.tools/tophat, https://sources.debian.org/src/tophat/ http://tophat.cbcb.umd.edu/ SCR_013035 tophat, TopHat1, Tophat2 2026-08-05 10:45:55 9575
MitoBreak
 
Resource Report
Resource Website
10+ mentions
MitoBreak (RRID:SCR_012949) MitoBreak data or information resource, data repository, database, storage service resource, service resource Database with curated datasets of mitochondrial DNA (mtDNA) rearrangements. Users may submit new mtDNA rearrangements. mitochondrial dna rearrangement, mitochondrial dna, deletion, duplication, linear, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:24170808 Free, The community can contribute to this resource biotools:mitobreak, OMICS_01640 https://bio.tools/mitobreak SCR_012949 2026-08-05 10:45:54 10
minfi
 
Resource Report
Resource Website
100+ mentions
minfi (RRID:SCR_012830) minfi data processing software, software application, data visualization software, data analysis software, software resource Software tools for analyzing and visualizing Illumina''s 450k array data. Illumina, array data, Analyze Illumina Infinium DNA methylation arrays, DNA methylation array, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: SWAN
has parent organization: Bioconductor
PMID:28035024 Free, Available for download, Freely available biotools:minfi, OMICS_00799, BioTools:minfi https://bio.tools/minfi, https://bio.tools/minfi, https://bio.tools/minfi SCR_012830 2026-08-05 10:45:53 390
affy
 
Resource Report
Resource Website
1000+ mentions
affy (RRID:SCR_012835) Affy software resource, data processing software, software application, data analysis software Software R package of functions and classes for the analysis of oligonucleotide arrays manufactured by Affymetrix. Used to process probe level data and for exploratory oligonucleotide array analysis. analysis, oligonucleotide, array, Affymetrix, process, probe, data, function, bio.tools is listed by: OMICtools
is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: affydata
is related to: R Project for Statistical Computing
is related to: OMICtools
Danish Biotechnology Instrument Center PMID:14960456 Free, Available for download, Freely available BioTools:affy, OMICS_00740, biotools:affy https://bio.tools/affy, https://sources.debian.org/src/r-bioc-affy/ SCR_012835 Affymetrix, analysis of Affymetrix GeneChip data at the probe level, analysis of Affymetrix GeneChip data 2026-08-05 10:45:53 2996
edgeR
 
Resource Report
Resource Website
10000+ mentions
edgeR (RRID:SCR_012802) edgeR software resource, data processing software, software application, data analysis software Bioconductor software package for Empirical analysis of Digital Gene Expression data in R. Used for differential expression analysis of RNA-seq and digital gene expression data with biological replication. empirical, analysis, digital, gene, expression, data, R, RNA-seq data, bio.tools is used by: Glimma
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: SARTools
is related to: Bioconductor
works with: tximport
NHMRC 406657;
Independent Research Institutes Infrastructure Support Scheme 361646;
Victorian State Government OIS grant ;
Melbourne International Research Scholarship ;
Harris and IBS Honours scholarships
PMID:19910308
DOI:10.1093/bioinformatics/btp616
Free, Available for download, Freely available OMICS_01308, biotools:edger https://bio.tools/edger, https://sources.debian.org/src/r-bioc-edger/ SCR_012802 edgeR, empirical analysis of digital gene expression data in R, Empirical analysis of Digital Gene Expression data in R 2026-08-05 10:45:53 21899
IMGT - the international ImMunoGeneTics information system
 
Resource Report
Resource Website
500+ mentions
IMGT - the international ImMunoGeneTics information system (RRID:SCR_012780) IMGT data or information resource, portal, topical portal, database, data analysis service, production service resource, service resource, analysis service resource A high-quality integrated knowledge resource specialized in the immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibility complex (MHC) of human and other vertebrate species, and in the immunoglobulin superfamily (IgSF), MHC superfamily (MhcSF) and related proteins of the immune system (RPI) of vertebrates and invertebrates, serving as the global reference in immunogenetics and immunoinformatics. IMGT provides a common access to sequence, genome and structure Immunogenetics data, based on the concepts of IMGT-ONTOLOGY and on the IMGT Scientific chart rules. IMGT works in close collaboration with EBI (Europe), DDBJ (Japan) and NCBI (USA). IMGT consists of sequence databases, genome database, structure database, and monoclonal antibodies database, Web resources and interactive tools. immunogenetics, immunoinformatics, immunoglobulin, antibody, t cell receptor, major histocompatibility complex, immunoglobulin superfamily, major histocompatibility complex superfamily, protein, immune system, sequence, genome, structure, monoclonal antibody, gold standard, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: IMGT Repertoire
has parent organization: Montpellier 2 University; Montpellier; France
is parent organization of: IMGT/LIGM-DB
is parent organization of: IMGT/GENE-DB
is parent organization of: IMGT-ONTOLOGY
is parent organization of: IMGT/V-QUEST
is parent organization of: IMGT/HLA
CNRS ;
MESR ;
Reseau National des Genopoles ;
Region Languedoc-Roussillon ;
European Union BIOMED1 BIOCT930038;
European Union Biotechnology BIOTECH2 BIO4CT960037;
European Union 5th PCRDT Quality of Life and Management of Living Resources QLG2-2000-01287;
Agence Nationale de la recherche ANR BIOSYS06_135457;
EU ImmunoGrid IST-028069
PMID:18978023 nif-0000-03011, biotools:imgt https://bio.tools/imgt http://imgt.cines.fr SCR_012780 ImMunoGeneTics Information System, IMGT/LIGM, ImMunoGeneTics 2026-08-05 10:45:52 746
Probalign
 
Resource Report
Resource Website
10+ mentions
Probalign (RRID:SCR_013332) Probalign data processing software, image analysis software, software application, alignment software, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software that uses partition function posterior probability estimates to compute maximum expected accuracy multiple sequence alignments. Computes maximal expected accuracy multiple sequence alignments from partition function posterior probabilities.Produces accurate alignments on long and heterogeneous length datasets containing protein repeats. is used by: eProbalign
is listed by: OMICtools
is listed by: Debian
has parent organization: New Jersey Institute of Technology; New Jersey; USA
PMID:16954142
DOI:10.1093/bioinformatics/btl472
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00985 https://sources.debian.org/src/probalign/ SCR_013332 Probalign: multiple sequence alignment using partition function posterior probabilities 2026-08-05 10:45:54 16
GeneSigDB
 
Resource Report
Resource Website
10+ mentions
GeneSigDB (RRID:SCR_013275) GeneSigDB data or information resource, data repository, web service, data access protocol, storage service resource, software resource, database, data analysis service, production service resource, service resource, analysis service resource Database of traceable, standardized, annotated gene signatures which have been manually curated from publications that are indexed in PubMed. The Advanced Gene Search will perform a One-tailed Fisher Exact Test (which is equivalent to Hypergeometric Distribution) to test if your gene list is over-represented in any gene signature in GeneSigDB. Gene expression studies typically result in a list of genes (gene signature) which reflect the many biological pathways that are concurrently active. We have created a Gene Signature Data Base (GeneSigDB) of published gene expression signatures or gene sets which we have manually extracted from published literature. GeneSigDB was creating following a thorough search of PubMed using defined set of cancer gene signature search terms. We would be delighted to accept or update your gene signature. Please fill out the form as best you can. We will contact you when we get it and will be happy to work with you to ensure we accurately report your signature. GeneSigDB is capable of providing its functionality through a Java RESTful web service. gene, gene signature, curated gene signature, gene expression, gene expression signature, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Dana-Farber Cancer Institute
has parent organization: Computational Biology and Functional Genomics Laboratory at Harvard
Cancer Genome Research Institute ;
Dana-Farber Cancer Institute ;
Women's Cancers Program ;
Claudia Adams Barr Foundation ;
NLM 1R01 LM010129;
NCI 1U19 CA148065;
NHGRI 1P50 HG004233
PMID:22110038 biotools:genesigdb, nlx_149342 https://bio.tools/genesigdb SCR_013275 Gene Signature Data Base, GeneSigDB - Curated Gene Signatures Database 2026-08-05 10:45:53 24
PlantNATsDB - Plant Natural Antisense Transcripts DataBase
 
Resource Report
Resource Website
1+ mentions
PlantNATsDB - Plant Natural Antisense Transcripts DataBase (RRID:SCR_013278) PlantNATsDB data or information resource, database, data analysis service, production service resource, service resource, analysis service resource Natural Antisense Transcripts (NATs), a kind of regulatory RNAs, occur prevalently in plant genomes and play significant roles in physiological and/or pathological processes. PlantNATsDB (Plant Natural Antisense Transcripts DataBase) is a platform for annotating and discovering NATs by integrating various data sources involving approximately 2 million NAT pairs in 69 plant species. PlantNATsDB also provides an integrative, interactive and information-rich web graphical interface to display multidimensional data, and facilitate plant research community and the discovery of functional NATs. GO annotation and high-throughput small RNA sequencing data currently available were integrated to investigate the biological function of NATs. A ''''Gene Set Analysis'''' module based on GO annotation was designed to dig out the statistical significantly overrepresented GO categories from the specific NAT network. PlantNATsDB is currently the most comprehensive resource of NATs in the plant kingdom, which can serve as a reference database to investigate the regulatory function of NATs. natural antisense transcript, annotation, high-throughput, small rna sequencing, function, regulatory function, predict, sequence, small rna, blast, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
is related to: Gene Expression Omnibus
has parent organization: Zhejiang University; Zhejiang; China
National Natural Sciences Foundation of China 30971743;
National Natural Sciences Foundation of China 31050110121;
National Natural Sciences Foundation of China 31071659;
Ministry of Science and Technology of China 2009DFA32030;
Program for New Century Excellent Talents in University of China NCET-07-0740;
Huazhong Agricultural University Scientific and Technological Self-innovation Foundation 2010SC07
PMID:22058132 Free nlx_151492, biotools:plantnatsdb https://bio.tools/plantnatsdb SCR_013278 Plant Natural Antisense Transcripts DataBase 2026-08-05 10:45:58 9
Dali Server
 
Resource Report
Resource Website
500+ mentions
Dali Server (RRID:SCR_013433) software resource, data analysis service, production service resource, service resource, analysis service resource Network service for comparing protein structures in 3D. You submit the coordinates of a query protein structure and Dali compares them against those in the Protein Data Bank (PDB). You receive an email notification when the search has finished. In favourable cases, comparing 3D structures may reveal biologically interesting similarities that are not detectable by comparing sequences. Requests can also be submitted by e-mail to dali-server at helsinki dot fi. The body of the e-mail message must contain atomic coordinates in PDB format. If you want to know the structural neighbours of a protein already in the Protein Data Bank (PDB), you can find them in the Dali Database. If you want to superimpose two particular structures, you can do it in the pairwise DaliLite server. Academic users may download the DaliLite program for local use. Protein structure comparison server, protein structure, comparison server, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
has parent organization: University of Helsinki; Helsinki; Finland
PMID:20457744 Free, Freely available biotools:dali https://bio.tools/dali SCR_013433 Dali 2026-08-05 10:46:01 509
ENIGMA
 
Resource Report
Resource Website
100+ mentions
ENIGMA (RRID:SCR_013400) software resource, data processing software, software application, data analysis software A software tool to extract gene expression modules from perturbational microarray data, based on the use of combinatorial statistics and graph-based clustering. The modules are further characterized by incorporating other data types, e.g. GO annotation, protein interactions and transcription factor binding information, and by suggesting regulators that might have an effect on the expression of (some of) the genes in the module. Version : ENIGMA 1.1 used GO annotation version : Aug 29th 2007 genome, gene, genetic software, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Ghent University; Ghent; Belgium
is parent organization of: ENIGMA-DTI Pipeline
PMID:18402676 biotools:enigma, nlx_144365 https://bio.tools/enigma SCR_013400 2026-08-05 10:46:00 130
PsyGeNET
 
Resource Report
Resource Website
10+ mentions
PsyGeNET (RRID:SCR_014406) data or information resource, data processing software, software application, data analysis software, software resource, database Knowledge platform on psychiatric disorders and their genes. Resource for exploratory analysis of psychiatric diseases and their associated genes. PsyGeNET is composed of database and set of analysis tools and is the result of the integration of information from DisGeNET and data extracted from the literature by text mining, followed by curation by domain experts. psychiatric disease, associated gene, database, analysis tool, bio.tools is used by: DisGeNET
is listed by: Debian
is listed by: bio.tools
Psychiatric disorder DOI:10.1093/bioinformatics/btv301 Available for the research community biotools:psygenet2r https://bio.tools/psygenet2r SCR_014406 Psychiatric disorders Gene association NETwork, Psychiatric disorders Gene association Network 2026-08-05 10:46:09 11
COPASI
 
Resource Report
Resource Website
100+ mentions
COPASI (RRID:SCR_014260) COPASI data processing software, software application, simulation software, data analysis software, standalone software, software resource Software application for simulation and analysis of biochemical network models and their dynamics. COPASI supports models in the SBML standard and can simulate their behavior using ODEs or Gillespies stochastic simulation algorithm. Arbitrary discrete events can be included in such simulations. Models in COPASI are based on reactions that convert a set of species into another set of species. Simulation can be performed either with stochastic kinetics or with differential equations. COPASI also includes various methods of analysis and data visualization. standalone software, simulation software, data analysis, biochemical system simulator, biochemical network model, biochemical network dynamics, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1093/bioinformatics/btl485 Free, Available for download, Acknowledgement requested biotools:copasi https://bio.tools/copasi SCR_014260 COPASI: Biochemical System Simulator 2026-08-05 10:46:04 435
CYANA
 
Resource Report
Resource Website
100+ mentions
CYANA (RRID:SCR_014229) software resource, data processing software, software application, data analysis software Software for automated structure calculation of biological macromolecules on basis of conformational constraints from nuclear magnetic resonance. Program for automated NMR protein structure calculation. CYANA requires a sufficient list of assigned chemical shifts and lists of cross-peak positions and columns from 2D, 3D, or4D NOESY spectra in order to calculate the assignment of the NOESY cross-peaks and the 3D structure of the protein in solution. protein structure, nmr, noesy, 3d structure, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Goethe University Frankfurt am Main; Hessen; Germany
has parent organization: RIKEN
PMID:15318003
PMID:25801209
Available to the academic community, Available to commercial user, Pay for license SCR_021949, biotools:cyana http://www.las.jp/english/products/cyana.html, https://bio.tools/cyana, https://dbpedia.org/page/CYANA_(software) SCR_014229 2026-08-05 10:46:08 425

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