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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
MOLEonline
 
Resource Report
Resource Website
10+ mentions
MOLEonline (RRID:SCR_018314) web service, data access protocol, software resource, production service resource, service resource, analysis service resource Interactive web based tool for analyzing biomacromolecular channels, tunnels and pores. Enables two modes of calculation with one dedicated to analysis of channels and another for transmembrane pores. Can use PDB and mmCIF formats. Can analyze biomacromolecular structures stemming from NMR, X-ray and cryo-EM techniques. Interconnected with PDBe, CSA, ChannelsDB, OPM, UniProt to help setup and analysis of acquired results. Provides analytics for detection and structural characterization of channels and information about their physicochemical features. biomacromolecular channel, analysis, biomacromolecular pore, biomacromolecular tunnel, transmembrane pore analysis, analysis, biomacromolecular sturcture, physicochemical feature works with: PDBe - Protein Data Bank in Europe
works with: CSA - Catalytic Site Atlas
works with: UniProt
PMID:29718451 Free, Freely available https://mole.upol.cz/online/ http://old.mole.upol.cz/ SCR_018314 MOLEonline 2.0 2026-08-05 10:46:59 30
Proteomic Data Commons
 
Resource Report
Resource Website
50+ mentions
Proteomic Data Commons (RRID:SCR_018273) PDC data or information resource, data repository, database, storage service resource, production service resource, service resource, analysis service resource Portal to make cancer related proteomic datasets easily accessible to public. Facilitates multiomic integration in support of precision medicine through interoperability with other resources. Developed to advance our understanding of how proteins help to shape risk, diagnosis, development, progression, and treatment of cancer. One of several repositories within NCI Cancer Research Data Commons which enables researchers to link proteomic data with other data sets (e.g., genomic and imaging data) and to submit, collect, analyze, store, and share data throughout cancer data ecosystem. PDC provides access to highly curated and standardized biospecimen, clinical, and proteomic data, intuitive interface to filter, query, search, visualize and download data and metadata. Provides common data harmonization pipeline to uniformly analyze all PDC data and provides advanced visualization of quantitative information. Cloud based (Amazon Web Services) infrastructure facilitates interoperability with AWS based data analysis tools and platforms natively. Application programming interface (API) provides cloud-agnostic data access and allows third parties to extend functionality beyond PDC. Structured workspace that serves as private user data store and also data submission portal. Distributes controlled access data, such as patient-specific protein fasta sequence databases, with dbGaP authorization and eRA Commons authentication. Cancer, proteomic, data, precision medicine, diagnosis, treatment, analysis, biospeciment, clinical data, metadata is related to: Cancer Research Data Commons
has parent organization: National Cancer Institute
cancer Restricted SCR_018273 2026-08-05 10:47:01 66
Interactive Repeated Experiments Dotplot
 
Resource Report
Resource Website
Interactive Repeated Experiments Dotplot (RRID:SCR_018328) web service, data access protocol, software resource, production service resource, service resource, analysis service resource Web tool for creating interactive graphics. Enables authors to create interactive graphics from data obtained with repeated independent experiments. Designed for laboratory studies with repeated experiments. Interactive graphic, repeated independent experiment, repeated experiment data, graph, analysis, dot plot NCATS UL1 TR000135 PMID:28974579 Free, Freely available SCR_018328 2026-08-05 10:47:02 0
DichroWeb
 
Resource Report
Resource Website
50+ mentions
DichroWeb (RRID:SCR_018125) web service, data access protocol, software resource, data analysis service, production service resource, service resource, analysis service resource Web server for analysis of protein circular dichroism spectra. Provides access to circular dichroism secondary structure calculation algorithms and reference databases. Used in analysis of protein secondary structures. Analysis, protein, circular dichroism spectra, secondary structure, reference database, algorithm, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of London; London; United Kingdom
BBSRC PMID:17896349
PMID:15215473
Restricted biotools:dichroweb https://bio.tools/dichroweb SCR_018125 2026-08-05 10:47:00 62
EMBL-EBI COVID-19 Portal
 
Resource Report
Resource Website
10+ mentions
EMBL-EBI COVID-19 Portal (RRID:SCR_018337) data or information resource, data repository, portal, disease-related portal, topical portal, database, storage service resource, service resource EMBL-EBI portal to enable researchers to upload, access and analyse COVID-19 related reference data and specialist datasets submitted to EMBL-EBI and other major centers for biomedical data. Used to facilitate data sharing and analysis to accelerate coronavirus research. The aim of the COVID-19 Data Portal is to facilitate data sharing and analysis, and to accelerate coronavirus research. EMBL-EBI and partners have set up the COVID-19 Data Portal, which will bring together relevant datasets submitted to EMBL-EBI and other major centres for biomedical data. The aim is to facilitate data sharing and analysis, and to accelerate coronavirus research. The COVID-19 Data Portal will enable researchers to upload, access and analyse COVID-19 related reference data and specialist datasets. The COVID-19 Data Portal will be the primary entry point into the functions of a wider project, the European COVID-19 Data Platform. COVID-19, COVID-19 data, sequence, expression, protein sequence, protein structure, proteome, translatome, analysis, EMBL-EBI is related to: EMBL-EBI Pathogens - COVID-19 COVID-19 Free, Freely available SCR_018816 https://www.covid19dataportal.org/, https://www.ebi.ac.uk/about/news/press-releases/embl-ebi-launches-covid-19-data-portal SCR_018337 EMBL-EBI COVID-19 Data Portal, COVID-19 Data Portal 2026-08-05 10:47:02 10
Watchdog
 
Resource Report
Resource Website
1+ mentions
Watchdog (RRID:SCR_018355) data processing software, data management software, software application, data analysis software, software resource Software workflow management system for automated and distributed analysis of large scale experimental data. Implemented in Java and is thus platform independent. Workflow management system, automated data analysis, next generation sequencing, large scale experimental data, analysis Free, Available for download, Freely available https://github.com/klugem/watchdog, https://anaconda.org/bioconda/watchdog-wms SCR_018355 2026-08-05 10:47:03 2
Big Data Processor
 
Resource Report
Resource Website
1+ mentions
Big Data Processor (RRID:SCR_018484) BDP data processing software, image analysis software, software application, software resource, image processing software Software tool for visual inspection and processing of big image data. Enables loading of Tiff and Hdf5 based image data. BDC supports cropping and saving of big image data including binning and bit depth conversion. Used for analysis of TB sized image data like light sheet microscopy or electron microscopy. Image, image processor, data processor, data, processing, analysis, image data, microscopy is a plug in for: Fiji Free, Available for download, Freely available https://github.com/embl-cba/fiji-plugin-bigDataProcessor SCR_018484 2026-08-05 10:47:02 2
Harmony
 
Resource Report
Resource Website
10+ mentions
Harmony (RRID:SCR_018809) data processing software, data acquisition software, image acquisition software, software application, image analysis software, software resource Harmony high content imaging and analysis software. Used to quantify complex cellular phenotypes. Designed for PerkinElmer high content screening systems. Imaging, analysis, cellular phenotype quantification, PerkinElmer, high content, screening system, cell phenotypic screening, live cell imaging, is related to: Perkin Elmer: Operetta CLS Restricted SCR_018809 Harmony 4.8 2026-08-05 10:47:05 29
RiboTaper
 
Resource Report
Resource Website
1+ mentions
RiboTaper (RRID:SCR_018880) software resource, data processing software, software application, data analysis software Software tool as analysis pipeline for ribosome profiling experiments, which exploits triplet periodicity of ribosomal footprints to call translated regions. Statistical approach that identifies translated regions on basis of characteristic three nucleotide periodicity of Ribo-seq data. Ribo-seq data, analysis, ribosome profiling experiment, triplet periodicity, ribosomal footprint, translated region, three nucleotide periodicity, data, ribosome profiling, bio.tools is listed by: bio.tools
is listed by: Debian
NIGMS R01 GM104962;
Berlin Institute for Medical Systems Biology
PMID:26657557 Free, Freely available biotools:ribotaper https://bioconda.github.io/recipes/ribotaper/README.html, https://bio.tools/ribotaper SCR_018880 2026-08-05 10:47:07 8
IMGT/StatClonotype
 
Resource Report
Resource Website
1+ mentions
IMGT/StatClonotype (RRID:SCR_018963) software resource, data processing software, software application, data analysis software Software tool to evaluate and visualize statistical significance of pairwise comparisons of IMGT clonotype (AA) diversity or expression, per variable,diversity, and joining gene of given IG or TR group, from NGS IMGT/HighV-QUEST statistical output. Antibody clonotype analysis based on NGS sequences. T cell receptor, antibody, immunoglobulin, immunoinformatics, next generation sequencing, statistical significance, clonotype diversity, clonotype expression, pairwise comparison, gene, NGS, analysis, antybody clonotype, bio.tools is listed by: bio.tools
is listed by: Debian
PMID:27667992 Free, Available for download, Freely available biotools:IMGt_StatClonotype https://bio.tools/IMGT_StatClonotype SCR_018963 IMGTStatClonotype, ImMunoGeneTics/StatClonotype 2026-08-05 10:47:07 3
ClinTrajAn
 
Resource Report
Resource Website
1+ mentions
ClinTrajAn (RRID:SCR_019018) data processing software, software application, data visualization software, data analysis software, software resource Software Python package for analysis of trajectories in clinical datasets. Trajectories analysis, clinical datasets, analysis, data, , bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:clintrajan https://bio.tools/clintrajan SCR_019018 2026-08-05 10:47:08 1
TwoSampleMR
 
Resource Report
Resource Website
500+ mentions
TwoSampleMR (RRID:SCR_019010) software resource, data processing software, software application, data analysis software Software R package for performing Mendelian randomization using genome wide association study summary data. GWAS data, genome wide associated study data, genome data, Mendelian randomization, analysis PMID:29846171 Free, Available for download, Freely available SCR_019010 2026-08-05 10:47:08 597
Protein Cross-Linking Database
 
Resource Report
Resource Website
1+ mentions
Protein Cross-Linking Database (RRID:SCR_021027) ProXL, proxl, Protein XL data or information resource, data access protocol, software resource, database, web service Web application and database designed for sharing, visualizing, and analyzing protein cross-linking mass spectrometry data with emphasis on structural analysis and quality control. Includes public and private data sharing capabilities, project based interface designed to ensure security and facilitate collaboration among multiple researchers. Used for private collaboration and public data dissemination. Protein cross-linking, mass spectrometry data, analysis, visualization, sharing, structural analysis, quality control, private collaboration, public data dissemination uses: Kojak
has parent organization: University of Washington; Seattle; USA
NIGMS P41 GM103533;
University of Washington Proteomics Resource
PMID:27302480 Free, Available for download, Freely available https://github.com/yeastrc/proxl-web-app SCR_021027 Protein XL Database 2026-08-05 10:47:20 5
StringTie
 
Resource Report
Resource Website
1000+ mentions
StringTie (RRID:SCR_016323) data processing software, software application, sequence analysis software, data analysis software, software resource Software application for assembling of RNA-Seq alignments into potential transcripts. It enables improved reconstruction of a transcriptome from RNA-seq reads. This transcript assembling and quantification program is implemented in C++ . assembling, RNA, sequence, transcript, gene, alignment, reconstruction, read, analysis, process, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
the Cancer Prevention and Research Institute of Texas ;
NHGRI R01 HG006677;
NIGMS R01 GM105705;
NHGRI R01 HG006102;
NCI R01 CA120185;
NCI R01 CA134292
PMID:25690850
DOI:10.1038/nbt.3122
Open source, Free, Freely available, Available for download biotools:stringtie, OMICS_07226 https://github.com/gpertea/stringtie, https://bio.tools/stringtie, https://sources.debian.org/src/stringtie/ SCR_016323 2026-08-05 10:46:34 4072
GIMME
 
Resource Report
Resource Website
1+ mentions
GIMME (RRID:SCR_014115) GIMME data processing software, software application, data analysis software, software toolkit, software resource Software Matlab toolbox for directed functional connectivity analysis of fMRI BOLD signal from predefined regions of interest. It recovers true structure of connections and estimates weights attributed to each connection. Obtains patterns at group and individual levels. Functional, connectivity, analysis, fMRI, BOLD, signal, predefined, region, pattern, BRAIN Initiative uses: MATLAB
is recommended by: BRAIN Initiative
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Pennsylvania; Philadelphia; USA
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
NIBIB EB022904;
NIBIB R21 EB015573;
NSF 0852147
PMID:22732562 Free, Available for download, Freely available SCR_014115 Group Iterative Multiple Model Estimation 2026-08-05 10:46:05 2
DESeq2
 
Resource Report
Resource Website
10000+ mentions
DESeq2 (RRID:SCR_015687) data processing software, software tool, software application, data analysis software, software resource Software package for differential gene expression analysis based on the negative binomial distribution. Used for analyzing RNA-seq data for differential analysis of count data, using shrinkage estimation for dispersions and fold changes to improve stability and interpretability of estimates. differential, gene, expression, analysis, binominal, distribution, RNA-seq data, Bioconductor, bio.tools is used by: Glimma
is used by: TEtranscripts
is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: SARTools
works with: tximport
International Max Planck Research School for Computational Biology and Scientific Computing ;
NCI T32 CA009337;
European Union’s 7th Framework Programme
Free, Available for download, Freely available biotools:deseq2 https://github.com/mikelove/DESeq2, https://bio.tools/deseq2 SCR_015687 2026-08-05 10:46:27 43994
Pipeline Pilot
 
Resource Report
Resource Website
100+ mentions
Pipeline Pilot (RRID:SCR_014917) software resource, data processing software, software application, data analysis software Software used to automate the process of accessing, analyzing and reporting scientific data. This software can be used by a person with little or no software development experience can create scientific protocols that can be executed through a variety of interfaces including: BIOVIA Web Port, other BIOVIA solutions such as BIOVIA Electronic Lab Notebook, Isentris, Chemical Registration and third-party applications such as Microsoft SharePoint. The protocols aggregate and provide immediate access to volumes of research data, they automate the scientific analysis of data and allow researchers to explore, visualize and report results. automation, accessing, analysis, analyzing, scientific data, aggregation. aggregate, research, scientific is listed by: SoftCite Commercial SCR_014917 2026-08-05 10:46:14 352
UMMPerfusion
 
Resource Report
Resource Website
1+ mentions
UMMPerfusion (RRID:SCR_015970) data processing software, image analysis software, software application, software toolkit, software resource Analysis software for dynamic contrast enhanced magnetic resonance images with implementation of a pixel-by-pixel deconvolution approach. It quantifies T1-weighted contrast-enhanced dynamic MR imaging (DCE-MRI) perfusion data as an OsiriX plug-in. DCE-MRI, t1, weighted, imaging, mr, magnetic, resonance, analysis, digital, perfusion, parameter, data, set, image, algorithm, contrast, pixel is affiliated with: Heidelberg University; Baden-Wurttemberg; Germany Heinrich-Vetter-Stiftung PMID:22832894 Open source, Available for download, Runs on Mac OS, Tutorial available SCR_015970 OsiriX plugin 2026-08-05 10:46:31 6
FreeContact
 
Resource Report
Resource Website
10+ mentions
FreeContact (RRID:SCR_016113) data processing software, image analysis software, software application, alignment software, software resource Alignment software for large-scale protein contact or protein-protein interaction prediction optimized for speed through shorter runtimes. FreeContact provides the opportunity to compute contact predictions in any environment (desktop or cloud). protein, structure, prediction, sequence, analysis, fast, contact, alignment, multiple is listed by: OMICtools
is related to: Debian
Alexander von Humboldt Foundation ;
German Ministry for Research and Education (BMBF: Bundesministerium fuer Bildung und Forschung) ;
Research Council of Norway 208481
PMID:24669753
DOI:10.1186/1471-2105-15-85
Open source, Free, Available for download OMICS_03520 https://rostlab.org/owiki/index.php/FreeContact, https://sources.debian.org/src/libfreecontact-perl/ SCR_016113 2026-08-05 10:46:33 21
Pilon
 
Resource Report
Resource Website
1000+ mentions
Pilon (RRID:SCR_014731) data processing software, software application, sequence analysis software, data analysis software, software resource Software tool to automatically improve draft assemblies and find variation among strains, including large event detection. FASTA files of genome along with one or more BAM files of reads aligned as input. Read alignment analysis is used to identify inconsistencies between input genome and evidence in reads, then attempts to make improvements to genome. automatically, improve, draft, assembly, variation, strain, genome, read, alignment, analysis, inconsistency, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is related to: shovill
is hosted by: GitHub
DOI:10.1371/journal.pone.0112963
DOI:10.1371/journal.pone.0112963
Available for download, Acknowledgement requested OMICS_14553, biotools:pilon https://github.com/broadinstitute/pilon/wiki, https://bio.tools/pilon, https://sources.debian.org/src/pilon/ SCR_014731 2026-08-05 10:46:13 3102

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