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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Tetraodon Genome Browser
 
Resource Report
Resource Website
1+ mentions
Tetraodon Genome Browser (RRID:SCR_007079) data or information resource, database, portal, topical portal The initial objective of Genoscope was to compare the genomic sequences of this fish to that of humans to help in the annotation of human genes and to estimate their number. This strategy is based on the common genetic heritage of the vertebrates: from one species of vertebrate to another, even for those as far apart as a fish and a mammal, the same genes are present for the most part. In the case of the compact genome of Tetraodon, this common complement of genes is contained in a genome eight times smaller than that of humans. Although the length of the exons is similar in these two species, the size of the introns and the intergenic sequences is greatly reduced in this fish. Furthermore, these regions, in contrast to the exons, have diverged completely since the separation of the lineages leading to humans and Tetraodon. The Exofish method, developed at Genoscope, exploits this contrast such that the conserved regions which can be identified by comparing genomic sequences of the two species, correspond only to coding regions. Using preliminary sequencing results of the genome of Tetraodon in the year 2000, Genoscope evaluated the number of human genes at about 30,000, whereas much higher estimations were current. The progress of the annotation of the human genome has since supported the Genoscope hypothesis, with values as low as 22,000 genes and a consensus of around 25,000 genes. The sequencing of the Tetraodon genome at a depth of about 8X, carried out as a collaboration between Genoscope and the Whitehead Institute Center for Genome Research (now the Broad Institute), was finished in 2002, with the production of an assembly covering 90 of the euchromatic region of the genome of the fish. This has permitted the application of Exofish at a larger scale in comparisons with the genome of humans, but also with those of the two other vertebrates sequenced at the time (Takifugu, a fish closely related to Tetraodon, and the mouse). The conserved regions detected in this way have been integrated into the annotation procedure, along with other resources (cDNA sequences from Tetraodon and ab initio predictions). Of the 28,000 genes annotated, some families were examined in detail: selenoproteins, and Type 1 cytokines and their receptors. The comparison of the proteome of Tetraodon with those of mammals has revealed some interesting differences, such as a major diversification of some hormone systems and of the collagen molecules in the fish. A search for transposable elements in the genomic sequences of Tetraodon has also revealed a high diversity (75 types), which contrasts with their scarcity; the small size of the Tetraodon genome is due to the low abundance of these elements, of which some appear to still be active. Another factor in the compactness of the Tetraodon genome, which has been confirmed by annotation, is the reduction in intron size, which approaches a lower limit of 50-60 bp, and which preferentially affects certain genes. The availability of the sequences from the genomes of humans and mice on one hand, and Takifugu and Tetraodon on the other, provide new opportunities for the study of vertebrate evolution. We have shown that the level of neutral evolution is higher in fish than in mammals. The protein sequences of fish also diverge more quickly than those of mammals. A key mechanism in evolution is gene duplication, which we have studied by taking advantage of the anchoring of the majority of the sequences from the assembly on the chromosomes. The result of this study speaks strongly in favor of a whole genome duplication event, very early in the line of ray-finned fish (Actinopterygians). An even stronger evidence came from synteny studies between the genomes of humans and Tetraodon. Using a high-resolution synteny map, we have reconstituted the genome of the vertebrate which predates this duplication - that is, the last common ancestor to all bony vertebrates (most of the vertebrates apart from cartilaginous fish and agnaths like lamprey). This ancestral karyotype contains 12 chromosomes, and the 21 Tetraodon chromosomes derive from it by the whole genome duplication and a surprisingly small number of interchromosomal rearrangements. On the contrary, exchanges between chromosomes have been much more frequent in the lineage that leads to humans. Sponsors: The project was supported by the Consortium National de Recherche en Genomique and the National Human Genome Research Institute. duplication, element, euchromatic, evolution, exon, fish, gene, genetic, actinopterygians, aganth, ancestor, cartilaginous, cdna, chromosome, coding, collagen, cytokine, diversity, genome, genomic, heritage, hormone, human, interchromossomal, intergenic, intron, karyotype, lineage, mammal, molecule, mouse, nigroviridis, protein, proteome, pufferfish, receptor, region, selenoprotein, sequence, size, specie, synteny, system, takifugu, tetraodon, transposable, vertebrate nif-0000-20997 SCR_007079 TGB 2026-09-12 12:56:49 8
RTPrimerDB- The Real-Time PCR and Probe Database
 
Resource Report
Resource Website
10+ mentions
RTPrimerDB- The Real-Time PCR and Probe Database (RRID:SCR_007106) RTPrimerDB data or information resource, data repository, database, service resource, storage service resource Database for primer and probe sequences used in real-time PCR assays employing popular chemistries (SYBR Green I, Taqman, Hybridization Probes, Molecular Beacon) to prevent time-consuming primer design and experimental optimization, and to introduce a certain level of uniformity and standardization among different laboratories. Researchers are encouraged to submit their validated primer and probe sequence, so that other users can benefit from their expertise. The database can be queried using the official gene name or symbol, Entrez or Ensembl Gene identifier, SNP identifier, or oligonucleotide sequence. Different options make it possible to restrict a query to a particular application (Gene Expression Quantification/Detection, DNA Copy Number Quantification/Detection, SNP Detection, Mutation Analysis, Fusion Gene Quantification/Detection, Chromatin immunoprecipitation (ChIP)), organism (Human, Mouse, Rat, and others) or detection chemistry. primer, probe, sequence, real-time pcr, gene, assay, real-time pcr assay, FASEB list is listed by: OMICtools
has parent organization: Ghent University; Ghent; Belgium
PMID:18948285
PMID:16381959
PMID:12519963
Public, The community can contribute to this resource nif-0000-03431, OMICS_02322 SCR_007106 2026-09-12 12:56:50 49
Chromosome 7 Annotation Project
 
Resource Report
Resource Website
10+ mentions
Chromosome 7 Annotation Project (RRID:SCR_007134) Chromosome 7 Annotation Project data or information resource, data repository, database, service resource, storage service resource Database containing the DNA sequence and annotation of the entire human chromosome 7, encompassing nearly 158 million nucleotides of DNA and 1917 gene structures, are presented; the most up to date collation of sequence, gene, and other annotations from all databases (eg. Celera published, NCBI, Ensembl, RIKEN, UCSC) as well as unpublished data. To generate a higher order description, additional structural features such as imprinted genes, fragile sites, and segmental duplications were integrated at the level of the DNA sequence with medical genetic data, including 440 chromosome rearrangement breakpoints associated with disease. The objective of this project is to generate a comprehensive description of human chromosome 7 to facilitate biological discovery, disease gene research and medical genetic applications. There are over 360 disease-associated genes or loci on chromosome 7. A major challenge ahead will be to represent chromosome alterations, variants, and polymorphisms and their related phenotypes (or lack thereof), in an accessible way. In addition to being a primary data source, this site serves as a weighing station for testing community ideas and information to produce highly curated data to be submitted to other databases such as NCBI, Ensembl, and UCSC. Therefore, any useful data submitted will be curated and shown in this database. All Chromosome 7 genomic clones (cosmids, BACs, YACs) listed in GBrowser and in other data tables are freely distributed. duplication, gene expression, family, fish, gene, gene annotation, genome, breakpoint, chromosome, chromosome 7, clinical, deletion, disease, dna sequence, human, insertion, inversion, polymorphism, rearrangement, segmental duplication, snp, translocation, annotation, data analysis service, blat, cosmid, bac, yac, biomaterial supply resource, malignant, non malignant, bio.tools is listed by: One Mind Biospecimen Bank Listing
is listed by: Debian
is listed by: bio.tools
PMID:12690205 Free, (Genomic clones) nif-0000-03550, biotools:chr7, r3d100012136 https://bio.tools/chr7, https://doi.org/10.17616/R3VP9V SCR_007134 The Chromosome 7 Annotation Project, Chromosome 7 Annotation Project 2026-09-12 12:56:50 13
Genes to Cognition: Neuroscience Research Programme
 
Resource Report
Resource Website
10+ mentions
Genes to Cognition: Neuroscience Research Programme (RRID:SCR_007121) data or information resource, portal, topical portal A neuroscience research program that studies genes, the brain and behavior in an integrated manner, established to elucidate the molecular mechanisms of learning and memory, and shed light on the pathogenesis of disorders of cognition. Central to G2C investigations is the NMDA receptor complex (NRC/MASC), that is found at the synapses in the central nervous system which constitute the functional connections between neurons. Changes in the receptor and associated components are thought to be in a large part responsible for the phenomenon of synaptic plasticity, that may underlie learning and memory. G2C is addressing the function of synapse proteins using large scale approaches combining genomics, proteomics and genetic methods with electrophysiological and behavioral studies. This is incorporated with computational models of the organization of molecular networks at the synapse. These combined approaches provide a powerful and unique opportunity to understand the mechanisms of disease genes in behavior and brain pathology as well as provide fundamental insights into the complexity of the human brain. Additionally, Genes to Cognition makes available its biological resources, including gene-targeting vectors, ES cell lines, antibodies, and transgenic mice, generated for its phenotyping pipeline. The resources are freely-available to interested researchers. cognition, gene, neuroscience is listed by: 3DVC
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Wellcome Trust ;
MRC ;
BBSRC ;
Gatsby Charitable Foundation ;
Human Frontiers Science Programme ;
European Union ;
Framework Programme ;
EPSRC ;
NSF
nif-0000-10235 SCR_007121 G2C Neuroscience Research Program, G2C Research Programme, Genes to Cognition: Neuroscience Research Program, Genes to Cognition, G2C, Genes to Cognition - Neuroscience Research Programme, Genes to Cognition-Neuroscience Research Programme, G2C Research Program 2026-09-12 12:56:50 20
National Institute on Aging Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS)
 
Resource Report
Resource Website
50+ mentions
National Institute on Aging Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) (RRID:SCR_007314) NIAGADS data or information resource, data repository, data set, database, service resource, storage service resource National genetics data repository facilitating access to genotypic and phenotypic data for Alzheimer's disease (AD). Data include GWAS, whole genome (WGS) and whole exome (WES), expression, RNA Seq, and CHIP Seq analyses. Data for the Alzheimer’s Disease Sequencing Project (ADSP) are available through a partnership with dbGaP (ADSP at dbGaP). Repository for many types of data generated from NIA supported grants and/or NIA funded biological samples. Data are deposited at NIAGADS or NIA-approved sites. Genetic Data and associated Phenotypic Data are available to qualified investigators in scientific community for secondary analysis. genetics, alzheimer's disease, genome-wide association study, neurodegenerative disease, genotype, phenotype, late adult human, dna marker, dna sequencing, rna expression, rna, dna, gene is recommended by: National Library of Medicine
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: NIH Data Sharing Repositories
is related to: Allen Institute for Brain Science
has parent organization: University of Pennsylvania Perelman School of Medicine; Pennsylvania; USA
Alzheimer's disease, Late-onset Alzheimer's disease, Aging NIA 3U24AG041689;
NIA U24 AG041689;
NIH Blueprint for Neuroscience Research
nif-0000-00179 http://www.nitrc.org/projects/niagads http://alois.med.upenn.edu/niagads/ SCR_007314 National Institute on Aging, NIA Genetics of Alzheimer's Disease Data Storage Site, Genetics of Alzheimer’s Disease Data Storage Site 2026-09-12 12:56:52 76
Biological General Repository for Interaction Datasets (BioGRID)
 
Resource Report
Resource Website
1000+ mentions
Biological General Repository for Interaction Datasets (BioGRID) (RRID:SCR_007393) BioGRID data or information resource, database Curated protein-protein and genetic interaction repository of raw protein and genetic interactions from major model organism species, with data compiled through comprehensive curation efforts. budding yeast, fission yeast, protein, gene, protein interaction, genetic interaction, model organism, interaction, dataset, gene annotation, phenotype, orthologous interaction, yeast, cellular interaction network, physical interaction, protein-peptide, protein-rna, protein-protein interaction, genetics, publication, raw protein, genetic interaction, web service, pathway, network, biology, gene mapping, statistics, bio.tools, FASEB list is used by: NIF Data Federation
is recommended by: National Library of Medicine
is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: re3data.org
is listed by: OMICtools
is listed by: DataCite
is listed by: NIH Data Sharing Repositories
is listed by: bio.tools
is listed by: Debian
is related to: TissueNet - The Database of Human Tissue Protein-Protein Interactions
is related to: Pathway Commons
is related to: Cytoscape
is related to: Interaction Reference Index
is related to: ConsensusPathDB
is related to: FlyMine
is related to: IMEx - The International Molecular Exchange Consortium
is related to: Integrated Molecular Interaction Database
is related to: PSICQUIC Registry
is related to: PSI-MI
is related to: NIH Data Sharing Repositories
is related to: Agile Protein Interactomes DataServer
is related to: Integrated Manually Extracted Annotation
has parent organization: Princeton University; New Jersey; USA
has parent organization: University of Edinburgh; Scotland; United Kingdom
has parent organization: University of Montreal; Quebec; Canada
works with: IMEx - The International Molecular Exchange Consortium
BBSRC ;
Canadian Institutes of Health Research ;
NCRR R01 RR024031;
NHGRI HG02223;
NIH Office of the Director R24 OD011194
PMID:23203989
PMID:21071413
PMID:16381927
PMID:12620108
Free, Freely available nif-0000-00432, r3d100010350, OMICS_01901, biotools:the_grid https://orip.nih.gov/comparative-medicine/programs/genetic-biological-and-information-resources, https://bio.tools/the_grid, https://doi.org/10.17616/R34C7G SCR_007393 , BioGRID, Biological General Repository for Interaction Datasets 2026-09-12 12:56:54 2824
Genetics of Learning Disability Study
 
Resource Report
Resource Website
1+ mentions
Genetics of Learning Disability Study (RRID:SCR_007266) data or information resource, portal, topical portal The Genetics of Learning Disability (GOLD) Study is aimed to identify the genes on the X chromosome that contribute to significant intellectual disability and to lead the way towards greater understanding of the mechanisms by which intellectual disability occurs. Ultimately the aim is to improve the services available to affected families. Sponsors: The work was supported by the European Community''s Seventh Framework Programme-the GEN2PHEN Project, the New South Wales Department of Health, the Australian NHMRC, the SMILE foundation, the WCH Foundation, D. Harwood, EU grant QLG3-CT- 2002-01810 (EURO-MRX), US National Institutes of Health (HD26202) to C.E.S., the South Carolina Department of Disabilities and Special Needs (SCDDSN), Action Medical Research and the Wellcome Trust. study, genetics, learning, disability, gene has parent organization: University of Cambridge; Cambridge; United Kingdom nif-0000-30285 SCR_007266 GOLD Study 2026-09-12 12:56:52 6
Electronic Cell Project
 
Resource Report
Resource Website
10+ mentions
Electronic Cell Project (RRID:SCR_007381) modeling software, simulation software, software application, software resource Software platform, general technologies and theoretical supports for computational biology with the grand aim to make precise whole cell simulation at the molecular level possible.Technologies include formalisms and techniques, including technologies to predict, obtain or estimate parameters such as reaction rates and concentrations of molecules in the cell. The E-Cell System is a software platform for modeling, simulation and analysis of complex, heterogeneous and multi-scale system like the cell. The E-Cell Project is open to anyone who shares the view with u that development of cell simulation technology, and, even if such ultimate goal might not be within ten years of reach yet, solving various conceptual, computational and experimental problems that will continue to arise in the course of pursuing it, may have a multitude of eminent scientific, medical and engineering impacts on our society. gene, protein, ontology, binary executable; software development tool, cell is listed by: Debian nif-0000-00378 https://sources.debian.org/src/ecell/ SCR_007381 E-Cell 2026-09-12 12:56:54 15
Center for Inherited Disease Research
 
Resource Report
Resource Website
100+ mentions
Center for Inherited Disease Research (RRID:SCR_007339) CIDR analysis service resource, biomaterial analysis service, data computation service, material analysis service, production service resource, resource, service resource, training service resource Next generation sequencing and genotyping services provided to investigators working to discover genes that contribute to disease. On-site statistical geneticists provide insight into analysis issues as they relate to study design, data production and quality control. In addition, CIDR has a consulting agreement with the University of Washington Genetics Coordinating Center (GCC) to provide statistical and analytical support, most predominantly in the areas of GWAS data cleaning and methods development. Completed studies encompass over 175 phenotypes across 530 projects and 620,000 samples. The impact is evidenced by over 380 peer-reviewed papers published in 100 journals. Three pathways exist to access the CIDR genotyping facility: * NIH CIDR Program: The CIDR contract is funded by 14 NIH Institutes and provides genotyping and statistical genetic services to investigators approved for access through competitive peer review. An application is required for projects supported by the NIH CIDR Program. * The HTS Facility: The High Throughput Sequencing Facility, part of the Johns Hopkins Genetic Resources Core Facility, provides next generation sequencing services to internal JHU investigators and external scientists on a fee-for-service basis. * The JHU SNP Center: The SNP Center, part of the Johns Hopkins Genetic Resources Core Facility, provides genotyping to internal JHU investigators and external scientists on a fee-for-service basis. Data computation service is included to cover the statistical genetics services provided for investigators seeking to identify genes that contribute to human disease. Human Genotyping Services include SNP Genome Wide Association Studies, SNP Linkage Scans, Custom SNP Studies, Cancer Panel, MHC Panels, and Methylation Profiling. Mouse Genotyping Services include SNP Scans and Custom SNP Studies. gene, genome, array, custom, dna, genome wide association study, genotyping, genotyping service, linkage scan, methylation profiling, hereditary disease, single gene disorder, snp, statistical genetics, whole genome, whole exome, exome sequencing, high throughput sequencing, single nucleotide polymorphism, sequencing, disease is listed by: NIDDK Information Network (dkNET)
has parent organization: Johns Hopkins University; Maryland; USA
Aging NHGRI ;
NCI ;
NEI ;
NIA ;
NIAAA ;
NIAMS ;
NICHD ;
NIDA ;
NIDCD ;
NIDCR ;
NIDDK ;
NIEHS ;
NIMH ;
NINDS ;
NHGRI N01-HG-65403;
US Department of Health and Human Services HHSN268200782096C;
S Department of Health and Human Services HHSN268201100011I;
S Department of Health and Human Services HHSN268201200008I;
NHGRI U01HG004438;
NHGRI U54HG006542
nif-0000-00223 SCR_007339 CIDR - Center for Inherited Disease Research 2026-09-12 12:56:53 207
CardioGenomics
 
Resource Report
Resource Website
1+ mentions
CardioGenomics (RRID:SCR_007248) CardioGenomics data or information resource, portal, topical portal The primary goal of the CardioGenomics PGA is to begin to link genes to structure, function, dysfunction and structural abnormalities of the cardiovascular system caused by clinically relevant genetic and environmental stimuli. The principal biological theme to be pursued is how the transcriptional network of the cardiovascular system responds to genetic and environmental stresses to maintain normal function and structure, and how this network is altered in disease. This PGA will generate a high quality, comprehensive data set for the functional genomics of structural and functional adaptation of the cardiovascular system by integrating expression data from animal models and human tissue samples, mutation screening of candidate genes in patients, and DNA polymorphisms in a well characterized general population. Such a data set will serve as a benchmark for future basic, clinical, and pharmacogenomic studies. Training and education are also a key focus of the CardioGenomics PGA. In addition to ongoing journal clubs and seminars, the PGA will be sponsoring symposia at major conferences, and developing workshops related to the areas of focus of this PGA. Information regarding upcoming events can be found in the Events section of this site, and information about training and education opportunities sponsored by CardioGenomics can be found on the Teaching and Education page. The CardioGenomics project came to a close in 2005. This server, cardiogenomics.med.harvard.edu, remains online in order to continue to distribute data that was generated by investigators under the auspices of the CardioGenomics Program for Genomic Applications (PGA). :Sponsors: This resource is supported by The National Heart, Lung and Blood Institute (NHLBI) of the NIH., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. genomics, clinical, genetic, environmental, stimulus, cardiovascular, disease, data, expression, gene, dna, polymorphism, population, pharmacogenomic, training, education has parent organization: Harvard University; Cambridge; United States THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-30296 http://www.cardiogenomics.org SCR_007248 The CardioGenomics Project 2026-09-12 12:56:52 6
eMERGE Network: electronic Medical Records and Genomics
 
Resource Report
Resource Website
1+ mentions
eMERGE Network: electronic Medical Records and Genomics (RRID:SCR_007428) eMERGE data or information resource, portal, topical portal A national consortium formed to develop, disseminate, and apply approaches to research that combine DNA biorepositories with electronic medical record (EMR) systems for large-scale, high-throughput genetic research. The consortium is composed of seven member sites exploring the ability and feasibility of using EMR systems to investigate gene-disease relationships. Themes of bioinformatics, genomic medicine, privacy and community engagement are of particular relevance to eMERGE. The consortium uses data from the EMR clinical systems that represent actual health care events and focuses on ethical issues such as privacy, confidentiality, and interactions with the broader community. human, clinical, dna, alzheimer's disease, genome, genomics, gene, genetic, nervous system disease, nucleotide polymorphism, phenotype, bioinformatics, genomic medicine, privacy, community engagement, emr, electronic medical record is related to: PheKB
is related to: NCBI database of Genotypes and Phenotypes (dbGap)
is related to: PheWAS Catalog
has parent organization: Vanderbilt University; Tennessee; USA
Aging NIGMS ;
NHGRI
Available to the research community nif-0000-00539 SCR_007428 eMERGE Network: electronic Medical Records & Genomics - A consortium of biorepositories linked to electronic medical records data for conducting genomics studies, eMERGE Network: electronic Medical Records Genomics, eMERGE Network: electronic Medical Records & Genomics, eMERGE Network, electronic Medical Records & Genomics, The eMERGE Network: electronic Medical Records & Genomics 2026-09-12 12:56:54 2
aneurIST
 
Resource Report
Resource Website
1+ mentions
aneurIST (RRID:SCR_007427) aneurIST data or information resource, disease-related portal, portal, topical portal Project focused on cerebral aneurysms and provides integrated decision support system to assess risk of aneurysm rupture in patients and to optimize their treatments. IT infrastructure has been developeded for management and processing of vast amount of heterogeneous data acquired during diagnosis. gene, genetic, adult, cerebral aneurysm, cerebral brain hemorrhage, cerebral hemorrhage, cerebral parenchymal hemorrhage, cerebral hemorrhage, clinical, genomic, human, intracerebral hemorrhage, intracranial aneurysm, subarachnoid hemorrhage, risk, aneurysm rupture, patient, treatment, infrastructure, platform, genomics, disease, personalized risk assessment, bioinformatics, clinical, data management, data integration, data processing, software tool, cerebrum has parent organization: Pompeu Fabra University; Barcelona; Spain Cerebral aneurysm, Subarachnoid hemorrhage, Aging European Union ;
Sixth FPPriority 2 of the Information Society Technologies IST
nif-0000-00538 http://www.cilab.upf.edu/aneurist1/ SCR_007427 aneurIST - Integrated Biomedical Informatics for the Management of Cerebral Aneurysms, (at)neurIST, (at)neurIST - Integrated Biomedical Informatics for the Management of Cerebral Aneurysms 2026-09-12 12:56:54 5
Allen Human Brain Atlas
 
Resource Report
Resource Website
100+ mentions
Allen Human Brain Atlas (RRID:SCR_007416) atlas, data or information resource, data processing software, data visualization software, database, software application, software resource Multi modal atlas of human brain that integrates anatomic and genomic information, coupled with suite of visualization and mining tools to create open public resource for brain researchers and other scientists. Data include magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), histology and gene expression data derived from both microarray and in situ hybridization (ISH) approaches. Brain Explorer 2 is desktop software application for viewing human brain anatomy and gene expression data in 3D. atlas, human, brain, anatomic, genomic, data, visualization, mining, tool, MRI, DTI, histology, gene, expression is related to: Speech Language Disorders Database
has parent organization: Allen Institute for Brain Science
has parent organization: Allen Brain Atlas
Individual private donors ;
U.S. Department of Health and Human Services 1C76HF15069;
U.S. Department of Health and Human Services 1C76HF19619
PMID:23041053 Free, Available for download, Freely available nif-0000-00506 http://humancortex.alleninstitute.org, http://human.brain-map.org/ SCR_007416 Human Cortex Study, Allen Institute for Brain Science Human Cortex Study, Allen Brain Atlas - Human Brain 2026-09-12 12:56:54 135
ARGONAUTE 2 - A database on mammalian microRNAs and their function in gene and pathway regulation
 
Resource Report
Resource Website
1+ mentions
ARGONAUTE 2 - A database on mammalian microRNAs and their function in gene and pathway regulation (RRID:SCR_007553) data computation service, data or information resource, database A database is a of mammalian miRNAs and their known or predicted regulatory targets. It provides information on origin of miRNAs, tissue specificity of their expressions and their known or proposed functions, their potential target genes as well as data on miRNA families based on their co-expression and proteins known to be involved in miRNA processing. This database also contains three other navigation tools that can be used to find information relating to miRNA: 1.) Gene Annotations is an information retrieval system for miRNA target genes. It provides comprehensive information from sequence databases and allows to simultaneously search PubMed with all synonyms of a given gene. 2.) miRNA Motif Finder - Argonaute predicts miRNA motifs binding to the gene sequence of the user. The miRNA mature sequences are taken from Agronaute 2 database. miRNA Motif Finder - Custom predicts miRNA motifs binding to the gene sequence, both the gene sequence and miRNA mature sequences provided by the user. 3.) miRNA Statistics provides statistics for the mature miRNA sequences from Argonaute 2 as well as for the miRNA sequences uploaded by the user. It provides statitics on the individual nucleotide as well as pattern of nucleotides apperaing in the sequence. gene, metabolic and signaling pathways, mirna, protein-protein interaction, rna sequence database has parent organization: Heidelberg University; Baden-Wurttemberg; Germany Deutsche Forschungsgemein ;
Federal Ministry of Research and Education
nif-0000-02567 http://argonaute.uni-hd.de SCR_007553 ARGONAUTE 2026-09-12 12:56:57 1
SNPper
 
Resource Report
Resource Website
50+ mentions
SNPper (RRID:SCR_001963) SNPper software resource Retrieve known single-nucleotide polymorphisms (SNPs) by position or by association with a gene; save, filter, analyze, display or export SNP sets; explore known genes using names or chromosome positions. single-nucleotide polymorphism, gene, chromosome is listed by: OMICtools
has parent organization: University of Florida; Florida; USA
PMID:12490454 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01926 SCR_001963 2026-09-12 12:55:35 50
Virtual Genetics Education Centre
 
Resource Report
Resource Website
Virtual Genetics Education Centre (RRID:SCR_001958) VGEC data or information resource, narrative resource, training material Hub of evaluated genetics-related teaching resources for teachers and learners in schools and higher education, health professionals and the general public. Suggest or submit a learning resource to the VGEC. Resources include: * simple experiments suitable for all ages * tutorial material * videos on useful techniques * current and relevant links to other evaluated resources The Virtual Genetics Education Centre (VGEC) * Provides information and genetics education resources for higher education, colleges, schools, health professionals and the general public. * Encourages collaboration in the development, evaluation and sharing of genetics education resources * provides links to, and evaluates, sources of information and educational material about genetics. * Explores innovative approaches to teaching and learning in genetics, such as the SWIFT project for example where Second Life is being used to teach some aspects of genetics in a virtual laboratory. education, genetics, development, teaching, dna, experiment, college student, child, adult, health professional, adolescent, k-12, gene, chromosome, video, evaluation, sharing, learning has parent organization: University of Leicester; Leicester; United Kingdom THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-10529 SCR_001958 Virtual Genetics Education Center, GENIE VGEC 2026-09-12 12:55:35 0
BioModels
 
Resource Report
Resource Website
100+ mentions
BioModels (RRID:SCR_001993) BIOMD data or information resource, data repository, database, portal, service resource, storage service resource, topical portal Repository of mathematical models of biological and biomedical systems. Hosts selection of existing literature based physiologically and pharmaceutically relevant mechanistic models in standard formats. Features programmatic access via Web Services. Each model is curated to verify that it corresponds to reference publication and gives proper numerical results. Curators also annotate components of models with terms from controlled vocabularies and links to other relevant data resources allowing users to search accurately for models they need. Models can be retrieved in SBML format and import/export facilities are being developed to extend spectrum of formats supported by resource. FAIR sharing, mathematical model, computational model, simulation, kinetic model, annotation, web service, data analysis service, systems biology, biological model, biology, molecular biology, nucleotide sequence, gene expression, protein, gene, dna, rna, genetics, gold standard is listed by: 3DVC
is listed by: re3data.org
is listed by: DataCite
is related to: SBML
is related to: PathCase Pathways Database System
has parent organization: European Bioinformatics Institute
is parent organization of: Kinetic Simulation Algorithm Ontology
BBSRC BB/F010516/1;
NIGMS R01 GM070923
PMID:20587024
PMID:16381960
CC0, Public Domain Dedication, Cf. our terms of use. nif-0000-02609, r3d100010789 http://www.ebi.ac.uk/biomodels/ SCR_001993 BioModels Database - A Database of Annotated Published Models, BioModels Database, BioModels 2026-09-12 12:55:35 255
ASPGD
 
Resource Report
Resource Website
100+ mentions
ASPGD (RRID:SCR_002047) ASPGD, ASPGD LOCUS, ASPGD REF data or information resource, data repository, database, service resource, storage service resource Database of genetic and molecular biological information about the filamentous fungi of the genus Aspergillus including information about genes and proteins of Aspergillus nidulans and Aspergillus fumigatus; descriptions and classifications of their biological roles, molecular functions, and subcellular localizations; gene, protein, and chromosome sequence information; tools for analysis and comparison of sequences; and links to literature information; as well as a multispecies comparative genomics browser tool (Sybil) for exploration of orthology and synteny across multiple sequenced Sgenus species. Also available are Gene Ontology (GO) and community resources. Based on the Candida Genome Database, the Aspergillus Genome Database is a resource for genomic sequence data and gene and protein information for Aspergilli. Among its many species, the genus contains an excellent model organism (A. nidulans, or its teleomorph Emericella nidulans), an important pathogen of the immunocompromised (A. fumigatus), an agriculturally important toxin producer (A. flavus), and two species used in industrial processes (A. niger and A. oryzae). Search options allow you to: *Search AspGD database using keywords. *Find chromosomal features that match specific properties or annotations. *Find AspGD web pages using keywords located on the page. *Find information on one gene from many databases. *Search for keywords related to a phenotype (e.g., conidiation), an allele (such as veA1), or an experimental condition (e.g., light). Analysis and Tools allow you to: *Find similarities between a sequence of interest and Aspergillus DNA or protein sequences. *Display and analyze an Aspergillus sequence (or other sequence) in many ways. *Navigate the chromosomes set. View nucleotide and protein sequence. *Find short DNA/protein sequence matches in Aspergillus. *Design sequencing and PCR primers for Aspergillus or other input sequences. *Display the restriction map for a Aspergillus or other input sequence. *Find similarities between a sequence of interest and fungal nucleotide or protein sequences. AspGD welcomes data submissions. function, gene, gene name, annotation, aspergillus, aspergillus nidulans, chromosome, community, dna, genome, genomic, localization, orthology, phenotype, protein, protein-coding genes, s. cerevisiae, sequence, allele, data analysis service, bio.tools, FASEB list is used by: NIF Data Federation
is listed by: bio.tools
is listed by: Debian
is related to: Candida Genome Database
is related to: AmiGO
has parent organization: Stanford University School of Medicine; California; USA
has parent organization: Broad Institute
NIAID R01 AI077599 PMID:19773420 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-12244, biotools:aspgd http://www.aspergillusgenome.org/, https://bio.tools/aspgd SCR_002047 Aspergillus Genome Database, ASPGD REF, ASPGD LOCUS 2026-09-12 12:55:36 218
Wellcome Trust Case Control Consortium
 
Resource Report
Resource Website
100+ mentions
Wellcome Trust Case Control Consortium (RRID:SCR_001973) WTCCC data or information resource Consortium of 50 research groups across the UK to harness the power of newly-available genotyping technologies to improve our understanding of the aetiological basis of several major causes of global disease. The consortium has gathered genotype data for up to 500,000 sites of genome sequence variation (single nucleotide polymorphisms or SNPs) in samples ascertained for the disease phenotypes. Analysis of the genome-wide association data generated has lead to the identification of many SNPs and genes showing evidence of association with disease susceptibility, some of which will be followed up in future studies. In addition, the Consortium has gained important insights into the technical, analytical, methodological and biological aspects of genome-wide association analysis. The core of the study comprised an analysis of 2,000 samples from each of seven diseases (type 1 diabetes, type 2 diabetes, coronary heart disease, hypertension, bipolar disorder, rheumatoid arthritis and Crohn's disease). For each disease, the case samples have been ascertained from sites widely distributed across Great Britain, allowing us to obtain considerable efficiencies by comparing each of these case populations to a common set of 3,000 nationally-ascertained controls also from England, Scotland and Wales. These controls come from two sources: 1,500 are representative samples from the 1958 British Birth Cohort and 1,500 are blood donors recruited by the three national UK Blood Services. One of the questions that the WTCCC study has addressed relates to the relative merits of these alternative strategies for the generation of representative population cohorts. Genotyping for this main Case Control study was conducted by Affymetrix using the (commercial) Affymetrix 500K chip. As part of this study a total of 17,000 samples were typed for 500,000 SNPs. There are two additional components to the study. First, the WTCCC award is part-funding a study of host resistance to infectious diseases in African populations. The same approach has been used to type 2,000 cases of tuberculosis (TB) and 2,000 cases of malaria, as well as 2,000 shared controls. As well as addressing diseases of major global significance, and extending WTCCC coverage into the area of infectious disease, the inclusion of samples of African origin has obvious benefits with respect to methodological aspects of genome-wide association analysis. Second, the WTCCC has, for four additional diseases (autoimmune thyroid disease, breast cancer, ankylosing spondylitis, multiple sclerosis), completed an analysis of 15,000 SNPs designed to represent a large proportion of the known non-synonymous coding SNPs across the genome. This analysis has been performed at the WTSI using a custom Infinium chip (Illumina). Data release The genotypic data of the control samples (1958 British Birth Cohort and UK Blood Service) and from seven diseases analyzed in the main study are now available to qualified researchers. Summary genotype statistics for these collections are available directly from the website. Access to the individual-level genotype data and summary genotype statistics is by application to the Consortium Data Access Committee (CDAC) and approval subject to a Data Access Agreement. WTCCC2: A further round of GWA studies were funded in April 2008. These include 15 WTCCC-collaborative studies and 12 independent studies be supported totaling approximately 120,000 samples. Many of the studies represent major international collaborative networks that have together assembled large sample collections. WTCCC2 will perform genome-wide association studies in 13 disease conditions: Ankylosing spondylitis, Barrett's oesophagus and oesophageal adenocarcinoma, glaucoma, ischaemic stroke, multiple sclerosis, pre-eclampsia, Parkinson's disease, psychosis endophenotypes, psoriasis, schizophrenia, ulcerative colitis and visceral leishmaniasis. WTCCC2 will also investigate the genetics of reading and mathematics abilities in children and the pharmacogenomics of statin response. Over 60,000 samples will be analyzed using either the Affymetrix v6.0 chip or the Illumina 660K chip. The WTCCC2 will also genotype 3,000 controls each from the 1958 British Birth cohort and the UK Blood Service control group, and the 6,000 controls will be genotyped on both the Affymetrix v6.0 and Illumina 1.2M chips. WTCCC3: The Wellcome Trust has provided support for a further round of GWA studies in January 2009. These include 5 WTCCC-collaborative studies to be carried out in WTCCC3 and 5 independent studies, across a range of diseases. Many of the studies represent major international collaborative networks that have together assembled large sample collections. WTCCC3 will perform genome-wide association studies in the following 4 disease conditions: primary biliary cirrhosis, anorexia nervosa, pre-eclampsia in UK subjects, and the interactions between donor and recipient DNA related to early and late renal transplant dysfunction. The WTCCC3 will also carry out a pilot in a study of the genetics of host control of HIV-1 infection. Over 40,000 samples will be analyzed using the Illumina 660K chip. The WTCCC3 will utilize the 6,000 control genotypes generated by the WTCCC2. gene, genomic, genetics, microarray, genome-wide association study, snp, genome-wide association, blood, dna, genotype, variation, genome, sequence variant, copy number variation, genetic variation, phenotype, disease is related to: Psychiatric Genomics Consortium
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Bipolar disorder, Coronary artery disease, Crohn's disease, Rheumatoid arthritis, Type 1 diabetes, Type 2 diabetes, Hypertension, Control, Multiple sclerosis, Breast cancer, Ankylosing spondylitis, Autoimmune thyroid disease, Malaria, Tuberculosis, Inflammatory bowel disease, Barrett's esophagus, Esophageal adenocarcinoma, Glaucoma, Ischemic stroke, Pre-eclampsia, Parkinson's disease, Psychosis endophenotypes, Psoriasis, Schizophrenia, Ulcerative colitis, Visceral leishmaniasis, Primary biliary cirrhosis, Anorexia nervosa, Human immunodeficiency virus, Renal transplant dysfunction, Diabetes Wellcome Trust ;
Bill and Melinda Gates Foundation ;
Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:17554300 Access to summary data and individual-level genotype data is available by application to the Wellcome Trust Case Control Consortium Data Access Committee. Access to data will be granted to qualified investigators for appropriate use. nif-0000-10551 SCR_001973 Wellcome Trust Case-Control Consortium (WTCCC) 2026-09-12 12:55:35 221
University of California at Los Angeles - Department of Energy Institute for Genomics and Proteomics
 
Resource Report
Resource Website
1+ mentions
University of California at Los Angeles - Department of Energy Institute for Genomics and Proteomics (RRID:SCR_001921) data computation service, data or information resource, database, organization portal, portal The UCLA-DOE Institute for Genomics and Proteomics carries out research in bioenergy, structural biology, genomics and proteomics, consistent with the research mission of the United States Department of Energy. Major interests of the 12 Principal Investigators and 9 Associate Members include systems approaches to organisms, structural biology, bioinformatics, and bioenergetic systems. The Institute sponsors 5 Core Technology Centers, for X-ray and NMR structural determination, bioinformatics and computation, protein expression and purification, and biochemical instrumentation. Services offered by this Institute: - Databases: * DIP (The Database of Interacting Proteins): The DIPTM database catalogs experimentally determined interactions between proteins. It combines information from a variety of sources to create a single, consistent set of protein-protein interactions. * ProLinks Database of Functional Linkages: The Prolinks database is a collection of inference methods used to predict functional linkages between proteins. These methods include the Phylogenetic Profile method which uses the presence and absence of proteins across multiple genomes to detect functional linkages; the Gene Cluster method, which uses genome proximity to predict functional linkage; Rosetta Stone, which uses a gene fusion event in a second organism to infer functional relatedness; and the Gene Neighbor method, which uses both gene proximity and phylogenetic distribution to infer linkage. - Data-to-Structure Servers: * SAVEs Structure Verification Server * Merohedral Twinning Test Server * SER Surface Entropy Reduction Server * VERIFY3D Structure Verification Server * ERRAT Structure Verification Server - Structure-to-Function Servers: * ProKnow Protein Functionator * Hot Patch Functional Site Locator expression, functional linkage, gene, biochemical instrumentation, bioenergetic system, bioenergy, bioinformatic, computation, genome, genomic, nmr, organism, protein, protein-protein interaction, proteomic, purification, structural biology, x-ray nif-0000-10491 SCR_001921 UCLA-DOE 2026-09-12 12:55:34 6

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