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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Knowledge Engineering from Experimental Design Resource Report Resource Website 1+ mentions |
Knowledge Engineering from Experimental Design (RRID:SCR_001238) | KEfED | software resource, software application | Knowledge engineering software for reasoning with scientific observations and interpretations. The software has three parts: (a) the KEfED model editor - a design editor for creating KEfED models by drawing a flow diagram of an experimental protocol; (b) the KEfED data interface - a spreadsheet-like tool that permits users to enter experimental data pertaining to a specific model; (c) a "neural connection matrix" interface that presents neural connectivity as a table of ordinal connection strengths representing the interpretations of tract-tracing data. This tool also allows the user to view experimental evidence pertaining to a specific connection. The KEfED model is designed to provide a lightweight representation for scientific knowledge that is (a) generalizable, (b) a suitable target for text-mining approaches, (c) relatively semantically simple, and (d) is based on the way that scientist plan experiments and should therefore be intuitively understandable to non-computational bench scientists. The basic idea of the KEfED model is that scientific observations tend to have a common design: there is a significant difference between measurements of some dependent variable under conditions specified by two (or more) values of some independent variable. | experimental design, observation, interpretation, reasoning, experimental data, observational assertion, knowledge engineering, java |
is listed by: FORCE11 is related to: Bioscholar has parent organization: Biomedical Informatics Research Network |
NIGMS R01-GM083871; NIMH 1R01MH079068-01A2; NCRR 1 U24 RR025736-01 |
PMID:21859449 | Free, Available for download, Freely available | nif-0000-07745 | https://wiki.birncommunity.org/display/NEWBIRNCC/Knowledge+Engineering+from+Experimental+Design+%28%27KEfED%27%29 | SCR_001238 | 2026-08-01 12:10:35 | 1 | |||||
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Spatial Analysis 3D Resource Report Resource Website |
Spatial Analysis 3D (RRID:SCR_002563) | SA3D | software resource, software application | A user-friendly, graphical user interface (GUI) that allows statistical and visual manipulations of real and simulated three-dimensional spatial point patterns. The analyses use files containing sets of X, Y, Z coordinates. These point patterns are frequently coordinates of cells of specific cell classes within in volumes of tissue derived from microscopy analyses. The analyses are scale independent so spatial analyses of coordinates from larger and smaller scale distributions are possible. The software can also generate sample sets of X, Y, Z coordinates for program exploration and modeling purposes. | eeg, meg, electrocorticography, matlab, modeling, magnetic resonance, position, quantification, simulation, statistical operation, cell, microscopy |
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) has parent organization: University of California at Santa Barbara; California; USA |
NIMH MH-069997; NEI EY-011087 |
PMID:18644136 | Free, Available for download, Freely available | nlx_155969 | http://www.nitrc.org/projects/sa3d | SCR_002563 | 2026-08-01 12:10:45 | 0 | |||||
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Neuroimaging Informatics Technology Initiative Resource Report Resource Website 100+ mentions |
Neuroimaging Informatics Technology Initiative (RRID:SCR_003141) | NIfTI | knowledge environment, training resource | Coordinated and targeted service, training, and research to speed the development and enhance the utility of informatics tools related to neuroimaging. The initial focus will be on tools that are used in fMRI. If NIfTI proves useful in addressing informatics issues in the fMRI research community, it may be expanded to address similar issues in other areas of neuroimaging. Objectives of NIfTI * Enhancement of existing informatics tools used widely in neuroimaging research * Dissemination of neuroimaging informatics tools and information about them * Community-based approaches to solving common problems, such as lack of interoperability of tools and data * Unique training activities and research career development opportunities to those in the tool-user and tool-developer communities * Research and development of the next generation of neuroimaging informatics tools | neuroimaging, neuroinformatics, technology, service, training, research, mri, fmri, software, algorithm or reusable library, c, computed tomography, developers, information resource, java, matlab, magnetic resonance, nifti, other information resource, pet, spect, software |
is used by: Stark Cross-Sectional Aging is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) is related to: GIFTI has parent organization: National Institute of Mental Health is parent organization of: NIfTI Data Format Working Group |
NIH Blueprint for Neuroscience Research ; NIMH ; NINDS |
Free, Freely available | nif-0000-00561 | http://www.nitrc.org/projects/nifti | http://www.bic.mni.mcgill.ca/nifti/ | SCR_003141 | NIfTI: Neuroimaging Informatics Technology Initiative, Neuroimaging Informatics Technology Initiative (NIfTI) | 2026-08-01 12:10:43 | 309 | ||||
|
Patient-Reported Outcomes Measurement Information System Resource Report Resource Website 1000+ mentions |
Patient-Reported Outcomes Measurement Information System (RRID:SCR_004718) | PROMIS | material resource, assessment test provider | Repository of person centered measures that evaluates and monitors physical, mental, and social health in adults and children. | adult, child, assessment, clinical, anger, pain, fatigue, physical function, depression, anxiety, social function, patient reported outcome, health, measure |
is recommended by: National Library of Medicine has parent organization: University of Washington; Seattle; USA |
NCCIH ; NCI ; NHLBI ; NIA ; NIAMS ; NIDA ; NIDCD ; NIDDK ; NIMH ; NINDS ; NINR ; OD |
nlx_143881 | http://www.healthmeasures.net/index.php?option=com_content&view=category&layout=blog&id=71&Itemid=817 | SCR_004718 | PROMIS, Patient Reported Outcomes Measurement Information System | 2026-08-01 12:10:50 | 2881 | ||||||
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KI Biobank - STAR Resource Report Resource Website 1+ mentions |
KI Biobank - STAR (RRID:SCR_005923) | KI Biobank - STAR | biomaterial supply resource, material resource | Large, ongoing, multifactorial study based on nation-wide ascertainment of patients with schizophrenia and bipolar disorder through the Swedish Twin Registry to include both neuroimaging data, neurocognitive function, molecular genetic data and early adverse environmental factors in the same model in a genetic sensitive design. Swedish schizophrenia research will benefit from this large study database of in total 240 affected and healthy twin pairs collected over a 5 year period. The specific aims are: * To elucidate neural endophenotypes for schizophrenia and bipolar disorder and to clarify the extent of overlap in these features between the two syndromes. * To investigate candidate genes and genomic regions for linkage and association with neural endophenotypes for schizophrenia and bipolar disease. * To determine the contributions of adverse prenatal and perinatal conditions to neural changes associated with schizophrenia and bipolar disease. Types of samples * EDTA whole blood * DNA * RNA Number of sample donors: 251 (June 2010) | twin, neuroimaging, environmental factor, environment, gene, endophenotype, behavioral symptom, phenotype, neural endophenotype, genetics, adverse fetal environment, prenatal event, perinatal condition, neurocognitive, mri |
uses: Swedish Twin Registry is listed by: One Mind Biospecimen Bank Listing has parent organization: Karolisnka Biobank |
Schizophrenia, Bipolar Disorder, Healthy, Normal control, Normal twin | NIMH ; Stockholm County Council ; ALF-medel |
nlx_149611 | http://ki.se/forskning/star | http://ki.se/ki/jsp/polopoly.jsp?d=29350&a=36309&l=en | SCR_005923 | Schizophrenia and Bipolar Disorder: Neural endophenotypes genetic liability and adverse fetal environment, KI Biobank - Schizophrenia Twins and Relatives, Schizophrenia Twins and Relatives | 2026-08-01 12:10:49 | 1 | ||||
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NIMH Publications Resource Report Resource Website |
NIMH Publications (RRID:SCR_008846) | NIMH Publications | narrative resource, data or information resource | Publications put out by the National Institute of Mental Health. Publications are available by topic: Disorders: * Attention Deficit Hyperactivity Disorder (ADHD) * Anxiety Disorders * Autism * Bipolar Disorder * Borderline Personality Disorder * Depression * Eating Disorders * Generalized Anxiety Disorder * Obsessive-Compulsive Disorder (OCD) * Panic Disorder * Post-Traumatic Stress Disorder * Schizophrenia * Social Phobia Populations * Older Adults * Men''s Mental Health * Women''s Mental Health * Children and Adolescents Research * Basic Research * Clinical Research and Trials * Research Funding * Mental Health Services Research Other * Coping with Traumatic Events * Genetics * HIV/AIDS * Imaging * Medications * NIMH * Prevention * Statistics * Suicide Prevention * Treatments | spanish, mental health, mental disease, human, booklet, brochure, fact sheet | has parent organization: National Institute of Mental Health | NIMH | nlx_146238 | SCR_008846 | National Institute of Mental Health Publications | 2026-08-01 12:10:52 | 0 | |||||||
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ARGON Resource Report Resource Website 1+ mentions |
ARGON (RRID:SCR_021635) | simulation software, software resource, software application | Software tool as fast simulator of genetic data that samples from Discrete Time Wright Fisher process backwards in time. Used to simulate long chromosomes and large samples under DTWF, with computational time comparable to recent coalescent simulators. | DTWF, genetic data simulator, discrete time Wright Fisher, process backwards in time, large samples simulation, long chromosomes simulation, discrete time Wright Fisher, coalescent simulation | has parent organization: University of Oxford; Oxford; United Kingdom | NIMH R01 MH101244 | PMID:27312410 | Free, Available for download, Freely available | https://github.com/pierpal/ARGON | SCR_021635 | 2026-08-02 09:08:15 | 1 | |||||||
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SIMS Resource Report Resource Website 1+ mentions |
SIMS (RRID:SCR_025787) | software resource, software application | Software label transfer tool for single-cell RNA sequencing analysis. Scalable, Interpretable Modeling for Single-cell RNA-seq data classification. | label transfer, single-cell RNA sequencing analysis, single-cell RNA-seq data classification, | Schmidt Futures ; NHGRI 1RM1HG011543; NSF ; NIMH 1U24MH132628; University of California Office of the President ; QualcommInstitute |
PMID:38823397 | Free, Available for download, Freely available | SCR_025787 | scalable, interpretable machine learning for single cell | 2026-08-01 12:13:38 | 2 | ||||||||
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NIMP: Neuroanatomy-anchored Information Management Platform for Collaborative BICAN Data Generation Resource Report Resource Website |
NIMP: Neuroanatomy-anchored Information Management Platform for Collaborative BICAN Data Generation (RRID:SCR_024684) | NIMP | organization portal, data or information resource, portal | Web application that tracks the status of the BICAN consortium tissue samples and related data.NIMP is developed under NIH BRAIN Initiative's BICAN U24MH130988 award as a part of the coordinating unit for biostatistics, informatics, and engagement (CUBIE) for the BRAIN Initiative Cell Atlas Network (BICAN) program.NIMP consists of two portals for BICAN collaborative data generation: the Specimen Portal and the Sequence Library (SeqLib) Portal. The Specimen Portal focuses on tissue management from donors to brain slabs and annotated brain samples. The SeqLib Portal manages the workflow starting from tissue, all the way downstream to track data deposition to assay-dependent, data-modality-specific archives. Both portals work in tandem to generate multimodal genomic data that can be traced back to their anatomical origins using the Allen Brain Atlas. The portals provide multiple types of data interfaces through dashboards, APIs, faceted queries, and batch data ingestion and exporting. All of the underlying functionalities are achieved through a robust agile development strategy using NHash resource identifiers, metadata standardization, active combinatorial dashboarding, resource provenance linkage and rendering (e.g. Sankey diagrams), and dedicated interfaces with NIH Neuro Biobank, sequencing centers, NeMO, and the larger BICAN data ecosystem. | BICAN, BICAN consortium tissue samples and related data, data tracking, |
works with: Connectome Workbench is organization facet of: BRAIN Initiative Cell Atlas Network |
NIMH U24MH130988 | Restricted | https://specimenportal.com | SCR_024684 | BICAN Specimen Portal | 2026-08-02 09:08:51 | 0 | ||||||
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Research Services Branch National Institutes of Mental Health Resource Report Resource Website 500+ mentions |
Research Services Branch National Institutes of Mental Health (RRID:SCR_001633) | RSB | data or information resource, portal | Portal for NIH, NIMH, and NINDS scientific and computer resources including Mac sites, PC sites, Linux sites, intramural programs, intranet and the NIH JumpStart and Directory. | mac, pc, linux |
has parent organization: National Institutes of Health is parent organization of: ImageJ |
NIMH ; NINDS |
THIS RESOURCE IS NO LONGER IN SERVICE | nlx_156832 | SCR_001633 | Research Services Branch National Institutes of Mental Health National Institutes of Neurological Disorders and Stroke | 2026-08-02 09:03:12 | 547 | ||||||
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MRM NeAt (Neurological Atlas) Mouse Brain Database Resource Report Resource Website 1+ mentions |
MRM NeAt (Neurological Atlas) Mouse Brain Database (RRID:SCR_007053) | MRM NeAt | image collection, reference atlas, database, atlas, data or information resource | Comprehensive three-dimensional digital atlas database of the C57BL/6J mouse brain based on magnetic resonance microscopy images acquired on a 17.6-T superconducting magnet. This database consists of: Individual MRI images of mouse brains; three types of atlases: individual atlases, minimum deformation atlases and probabilistic atlases; the associated quantitative structural information, such as structural volumes and surface areas. Quantitative group information, such as variations in structural volume, surface area, magnetic resonance microscopy image intensity and local geometry, have been computed and stored as an integral part of the database. The database augments ongoing efforts with other high priority strains as defined by the Mouse Phenome Database focused on providing a quantitative framework for accurate mapping of functional, genetic and protein expression patterns acquired by a myriad of technologies and imaging modalities. You must register First (Mandatory) and then you may Download Images and Data. | phenotype, mouse, brain, computational biology, in vivo, mouse brain atlas, magnetic resonance microscopy, mouse brain morphometry, image registration, in vitro, 3d brain atlas, adult mouse, male, c57bl/6j, autosegmentation, probabilistic atlas, t2 weighted protocol |
is related to: Mouse Brain Image Visualizer (MBIV) is related to: MRM NeAt (Neurological Atlas) Mouse Brain Database Image Gallery has parent organization: University of Florida; Florida; USA is parent organization of: MRM NeAt (Neurological Atlas) Mouse Brain Database Image Gallery |
National High Magnetic Field Laboratory ; NIBIB R01 EB 0023304; NCRR P41 RR16105; NIMH P50 MH58911 |
PMID:16165303 PMID:18958199 |
Registration required | nlx_59497 | http://brainatlas.mbi.ufl.edu | SCR_007053 | Magnetic Resonance Microimaging Neurological Atlas Mouse Brain Database, MRM Neurological Atlas Mouse Brain Database, C57BL/6J Mouse Atlas, Atlas of Adult C57BL/6J Mouse Brain, MRM NeAt Mouse Brain Database | 2026-08-03 09:33:20 | 8 | ||||
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NIMH DIRP Scientific and Statistical Computing Core Resource Report Resource Website |
NIMH DIRP Scientific and Statistical Computing Core (RRID:SCR_006958) | SSCC, NIMH DIRP SSCC | topical portal, data or information resource, portal | Scientific and Statistical Computing Core of the NIMH Intramural Research Program supporting functional neuroimaging research at the NIH. This includes development of new data analysis techniques, their implementation in the AFNI software, advising researchers on the analysis methods, and instructing them in the use of software tools. Support methods: A. Provision of software for analysis for FMRI data (AFNI package: http://afni.nimh.nih.gov) * AFNI has been developed for the last 10 years by Dr Cox, et al. (6 years in Milwaukee, 4 years at NIMH) * Formal and informal instruction in the use of AFNI, including outlines of the statistical methods used in the programs * Installation of AFNI on NIH computers (Mac OS X, Unix, Linux) approximately 120 NIH systems have used AFNI in the last month (80 NIMH, 20 NINDS, 20 other) * Realtime monitoring of FMRI data at scanners * Continuing development of new modules for AFNI to meet needs of NIH researchers B. Consulting with NIH researchers about FMRI data analysis issues, concerns, and methods | neuroimaging, functional neuroimaging, research, data analysis, analysis, software, tool, fmri, statistics, computing | has parent organization: NIMH Division of Intramural Research Programs | NIMH | nlx_144305 | SCR_006958 | NIMH DIRP Scientific Statistical Computing Core, Scientific and Statistical Computing Core, DIRP Scientific and Statistical Computing Core, Scientific Statistical Computing Core | 2026-08-03 09:33:18 | 0 | |||||||
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BrainML Resource Report Resource Website |
BrainML (RRID:SCR_007087) | BrainML | data repository, standard specification, data or information resource, database, narrative resource, storage service resource, service resource |
Set of standards and practices for using XML to facilitate information exchange between user application software and neuroscience data repositories. It allows for common shared library routines to handle most of the data processing, but also supports use of structures specialized to the needs of particular neuroscience communities. This site also serves as a repository for BrainML models. (A BrainML model is an XML Schema and optional vocabulary files describing a data model for electronic representation of neuroscience data, including data types, formats, and controlled vocabulary. ) It focuses on layered definitions built over a common core in order to support community-driven extension. One such extension is provided by the new NIH-supported neuroinformatics initiative of the Society for Neuroscience, which supports the development of expert-derived terminology sets for several areas of neuroscience. Under a cooperative agreement, these term lists will be made available Open Source on this site. The repository function of this site includes the following features: * BrainML models are published in searchable, browsable form. * Registered users may submit new models or new versions of existing models to accommodate data of interest. * BrainML model schema and vocabulary files are made available at fixed URLs to allow software applications to reference them. * Users can check models and/or instance documents for correct format before submitting them using an online validation service. To complement the BrainML modeling language, a set of protocols have been developed for BrainML document exchange between repositories and clients, for indexing of repositories, and for data query. |
format, development, information, mechanism, metaformat, model, neuroinformatics, neuroscience, standard, terminology, validation, vocabulary, xml, data sharing, xml schema compact syntax, xml schema, interoperability, semantics |
is used by: Neurodatabase.org has parent organization: Weill Cornell Medical College; New York; USA |
Human Brain Project ; NIMH MH/NS57153; NINDS MH/NS57153 |
Public, The community can contribute to this resource | nif-0000-21070 | http://brainml.org | SCR_007087 | BrainML.org | 2026-08-03 09:33:15 | 0 | |||||
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Computational Neuroanatomy Group Resource Report Resource Website |
Computational Neuroanatomy Group (RRID:SCR_007150) | CNG | topical portal, data or information resource, software resource, portal | Multidisciplinary research team devoted to the study of basic neuroscience with a specific interest in the description and generation of dendritic morphology, and in its effect on neuronal electrophysiology. In the long term, they seek to create large-scale, anatomically plausible neural networks to model entire portions of a mammalian brain (such as a hippocampal slice, or a cortical column). Achievements by the CNG include the development of software for the quantitative analysis of dendritic morphology, the implementation of computational models to simulate neuronal structure, and the synthesis of anatomically accurate, large scale neuronal assemblies in virtual reality. Based on biologically plausible rules and biophysical determinants, they have designed stochastic models that can generate realistic virtual neurons. Quantitative morphological analysis indicates that virtual neurons are statistically compatible with the real data that the model parameters are measured from. Virtual neurons can be generated within an appropriate anatomical context if a system level description of the surrounding tissue is included in the model. In order to simulate anatomically realistic neural networks, axons must be grown as well as dendrites. They have developed a navigation strategy for virtual axons in a voxel substrate. | dendritic morphology, neuronal morphology, neuronal electrophysiology, mammalian brain, neural network, cell, model, morphology, network connectivity, basal ganglia, modeling software, hippocampus, hermissenda learning, caulescence, tree structure, neuron, virtual neural network, morphological class of neuron, virtual neuron, virtual brain, ca3 pyramidal cell, arborvitae, ca1 pyramidal cell, polymorphic cell, dg granule cell, axonal navigation, synaptic connectivity, neuroplasticity, neuroanatomy, neuroinformatics, computation, network model, neural circuit, cellular event, expression, ca3, ca1 pyramidal neuron, digital morphological reconstruction, digital reconstruction, dendrite, axon, neuronal tree, signaling pathway |
has parent organization: George Mason University: Krasnow Institute for Advanced Study is parent organization of: L-Measure is parent organization of: Hippocampus 3D Model |
NINDS ; NIMH ; NSF ; Human Brain Project |
nif-0000-00503 | http://krasnow.gmu.edu/cn3/index3.html | SCR_007150 | Computational Neuroanatomy Group at the Krasnow Institute for Advanced Study | 2026-08-03 09:33:17 | 0 | ||||||
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ModelDB Resource Report Resource Website 100+ mentions |
ModelDB (RRID:SCR_007271) | ModelDB | data repository, data or information resource, database, storage service resource, service resource | Curated database of published models so that they can be openly accessed, downloaded, and tested to support computational neuroscience. Provides accessible location for storing and efficiently retrieving computational neuroscience models.Coupled with NeuronDB. Models can be coded in any language for any environment. Model code can be viewed before downloading and browsers can be set to auto-launch the models. The model source code has to be available from publicly accessible online repository or WWW site. Original source code is used to generate simulation results from which authors derived their published insights and conclusions. | repository, collection, network, neuron, computational, neuroscience, model, simulation, neural, data |
is used by: NIF Data Federation lists: ModelRun is listed by: 3DVC is listed by: Biositemaps is listed by: Integrated Models is related to: SimToolDB is related to: NeuronDB is related to: NeuronVisio is related to: Integrated Manually Extracted Annotation is related to: Allen Institute for Brain Science has parent organization: Yale University; Connecticut; USA works with: MicrocircuitDB |
NIMH ; NINDS ; NCI ; Human Brain Project ; NIDCD P01 DC004732; NIDCD R01 DC009977 |
PMID:15218350 PMID:15055399 PMID:8930855 |
Free, Freely available, Acknowledgement requested | nif-0000-00004, r3d100011330 | https://doi.org/10.17616/R3P61F | SCR_007271 | Model_DB, Model Database, Model DB, Model-DB | 2026-08-03 09:33:19 | 304 | ||||
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National NeuroAIDS Tissue Consortium Resource Report Resource Website 10+ mentions |
National NeuroAIDS Tissue Consortium (RRID:SCR_007323) | NNTC | tissue bank, biomaterial supply resource, material resource, brain bank | Collects, stores, and distributes samples of nervous tissue, cerebrospinal fluid, blood, and other tissue from HIV-infected individuals. The NNTC mission is to bolster research on the effects of HIV infection on human brain by providing high-quality, well-characterized tissue samples from patients who died with HIV, and for whom comprehensive neuromedical and neuropsychiatric data were gathered antemortem. Researchers can request tissues from patients who have been characterized by: * degree of neurobehavioral impairment * neurological and other clinical diagnoses * history of drug use * antiretroviral treatments * blood and CSF viral load * neuropathological diagnosis The NNTC encourages external researchers to submit tissue requests for ancillary studies. The Specimen Query Tool is a web-based utility that allows researchers to quickly sort and identify appropriate NNTC specimens to support their research projects. The results generated by the tool reflect the inventory at a previous time. Actual availability at the local repositories may vary as specimens are added or distributed to other investigators. | human immunodeficiency virus, nervous tissue, cerebral spinal fluid, blood, tissue, brain, neuromedical data, neuropsychiatric data, tissue, plasma, peripheral blood mononuclear cell, serum, urine, spinal cord, nervous tissue, pituitary gland, trigeminal ganglia, dorsal root ganglion, peripheral nerve, lymph node, liver, spleen, adipose tissue, bone marrow, muscle, hair, heart, thymus, kidney, lung, eye, brain, ante-mortem, post-mortem, normal, subsyndromic, minor cognitive motor disorder, hiv - associated dementia, cytomegalovirus encephalitis, neurological impairment, traumatic brain injury, neurocognitive disease, frozen, fixed, aids, one mind tbi, asymptomatic neurocognitive impairment, minor cognitive disorder, gene array, snp |
is listed by: One Mind Biospecimen Bank Listing is related to: Manhattan HIV Brain Bank is related to: CHARTER - CNS HIV Antiretroviral Therapy Effects Research |
Human immunodeficiency virus, Neurocognitive disease, Normal, Subsyndromic, Minor Cognitive Motor Disorder, HIV - Associated Dementia, Cytomegalovirus Encephalitis, Neurological impairment, Infectious disease | NIMH ; NINDS ; NIH Blueprint for Neuroscience Research |
Public: The NNTC encourages external researchers to submit tissue requests for ancillary studies. | nif-0000-00193 | SCR_007323 | nntc.org, nntc | 2026-08-03 09:33:20 | 11 | |||||
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National Institute of Mental Health (NIMH) Human Genetics Initiative Resource Report Resource Website |
National Institute of Mental Health (NIMH) Human Genetics Initiative (RRID:SCR_007436) | data or information resource, software resource, database | The Connectivity Map aims to generate a detailed map that links gene patterns associated with disease to corresponding patterns produced by drug candidates and a variety of genetic manipulations. The Connectivity Map is the most comprehensive effort yet for using genomics in a drug-discovery framework. It allows researchers to screen compounds against genome-wide disease signatures, rather than a pre-selected set of target genes. Drugs are paired with diseases using sophisticated pattern-matching methods with a high level of resolution and specificity. To build a Connectivity Map, the Broad Institute brings together molecular biologists, genomics specialists, computational scientists, pharmacologists, chemists and chemical biologists, as well as expertise from across the breadth and depth of medicine.Connectivity map is a large public database of signatures of drugs and genes, and pattern-matching tools to detect similarities among these signatures.The parent site for the Broad Institute at MIT has a software library of software applications developed for use in genetic analysis. | gene, genome, small molecule | has parent organization: Broad Institute | NIMH | nif-0000-00629 | SCR_007436 | NIMH Human Genetics Initiative | 2026-08-03 09:33:22 | 0 | ||||||||
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Cognitive and Emotional Health Project: The Healthy Brain Resource Report Resource Website |
Cognitive and Emotional Health Project: The Healthy Brain (RRID:SCR_007390) | CEHP | topical portal, data or information resource, database, portal | Trans-NIH project to assess the state of longitudinal and epidemiological research on demographic, social and biologic determinants of cognitive and emotional health in aging adults and the pathways by which cognitive and emotional health may reciprocally influence each other. A database of large scale longitudinal study relevant to healthy aging in 4 domains was created based on responses of investigators conducting these studies and is available for query. The four domains are: * Cognitive Health * Emotional Health * Demographic and Social Factors * Biomedical and Physiologic Factors | healthy aging, cognitive health, demographics, longitudinal study, aging study, late adult human, cognition, emotion, adult human, longitudinal, epidemiology, psychosocial, questionnaire, social factor, physiologic factor | has parent organization: National Institutes of Health | Cognitive impairment, Emotional disorder, Aging | NIA ; NIMH ; NINDS |
nif-0000-00421 | SCR_007390 | Cognitive and Emotional Health Project (CEHP), Cognitive Emotional Health Project: The Healthy Brain, Cognitive Emotional Health Project, Cognitive and Emotional Health Project | 2026-08-03 09:33:27 | 0 | ||||||
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Olfactory Receptor DataBase Resource Report Resource Website 1+ mentions |
Olfactory Receptor DataBase (RRID:SCR_007830) | ORDB | data repository, production service resource, data analysis service, service resource, database, storage service resource, analysis service resource, data or information resource | Database of vertebrate olfactory receptors genes and proteins. It supports sequencing and analysis of these receptors by providing a comprehensive archive with search tools for this expanding family. The database also incorporates a broad range of chemosensory genes and proteins, including the taste papilla receptors (TPRs), vomeronasal organ receptors (VNRs), insect olfaction receptors (IORs), Caenorhabditis elegans chemosensory receptors (CeCRs), and fungal pheromone receptors (FPRs). ORDB currently houses chemosensory receptors for more than 50 organisms. ORDB contains public and private sections which provide tools for investigators to analyze the functions of these very large gene families of G protein-coupled receptors. It also provides links to a local cluster of databases of related information in SenseLab, and to other relevant databases worldwide. The database aims to house all of the known olfactory receptor and chemoreceptor sequences in both nucleotide and amino acid form and serves four main purposes: * It is a repository of olfactory receptor sequences. * It provides tools for sequence analysis. * It supports similarity searches (screens) which reduces duplicate work. * It provides links to other types of receptor information, e.g. 3D models. The database is accessible to two classes of users: * General public www users have full access to all the public sequences, models and resources in the database. * Source laboratories are the laboratories that clone olfactory receptors and submit sequences in the private or public database. They can search any sequence they deposited to the database against any private or public sequence in the database. This user level is suited for laboratories that are actively cloning olfactory receptors. | fungal, pheromone receptor, gene, chemosensory, chemosensory receptor, g protein-coupled receptor, olfaction receptor, protein, receptor, taste papilla receptor, vomeronasal organ receptor, olfactory receptor, nucleotide, amino acid, chemoreceptor sequence, olfactory receptor sequence, chemoreceptor, sequence |
is used by: NIF Data Federation is listed by: 3DVC is related to: Odor Molecules DataBase is related to: Integrated Manually Extracted Annotation has parent organization: Yale School of Medicine; Connecticut; USA |
Aging | Human Brain Project ; NIMH ; NIA ; NICD ; NINDS ; Multidisciplinary University Research Initiative ; National Aeronautics and Space Administration ; NIDCD RO1 DC 009977; NIDCD P01 DC 04732; NLM G08 LM05583 |
PMID:11752336 PMID:9847223 PMID:9218144 |
Public, Private, Acknowledgement requested, The community can contribute to this resource | nif-0000-03213 | SCR_007830 | Olfactory Receptors Database | 2026-08-03 09:33:33 | 4 | ||||
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NIMH Interdisciplinary Behavioral Science Center Resource Report Resource Website |
NIMH Interdisciplinary Behavioral Science Center (RRID:SCR_008085) | IBSC | topical portal, data or information resource, portal | THIS RESOURCE IS NO LONGER IN SERVICE, documented on February 07, 2013. A framework for understanding human cognition, grounded in principles specifying the character of human cognitive processes, and constrained by properties, of the underlying neural mechanisms. The Center will exploit this framework to guide formulation of explicit, testable models of normal and disordered cognition, including models of the development of cognitive functions and of their disintegration as a result of brain damage or disease. This site is intended as a public service and as a focal point for exchange of ideas among the participants in the Interdisciplinary Behavioral Science Center (IBSC). Public areas of the site provide information about the Center as a whole and about the various projects in the Center, as well as web-accessible documents and tools that we are making available as a public service. A fundamental tenet is that cognition is an emergent phenomenon, arising from the interactions of cooperating processing elements organized into specialized populations. One aim of the center will be to investigate the utility of explicit models that are formulated in terms of this approach, addressing many aspects of cognition including semantic knowledge, language processing, cognitive control, perception, learning and memory. A second aim will also investigate the principles that are embodied in the models, including principles of learning, processing and representation. Learning will be a central focus, since it plays a crucial role in cognitive development, acquisition of skills, formation of memories, and remediation of cognitive functions. A third aim of the Center will be to incorporate constraints from neuroscience. Findings from neuroscience will guide the specification of the principles and the formulation of domain-specific details of particular models, and will provide target experimental observations against which to assess the adequacy of the models. In addition, the Center will make use of neurophysiological methods in animals and functional brain imaging in humans to test predictions and generate additional data needed to constrain and inform model development. The Center will provide training funds for interdisciplinary research fellowships, to train junior scientists in the convergent use of behavioral, computational, and neuroscience methodologies. The outcome of the Centers efforts will be a fuller characterization of the nature of human cognitive processes, a clearer formulation of the underlying principles, and a more complete understanding of normal and disordered functions across many domains of cognition. This Center includes eight projects dedicated to various aspects of cognition and various general issues that arise in the effort to build explicit models that capture different aspects of cognition, and also includes an administrative core to help foster integration and provide computing resources. * Project 1: Functional and Neural Organization of Semantic Memory * Project 2: Interactive Processes in Language: Lexical Processing * Project 3: Interactive Processes in Language: Sentence Processing * Project 4: Mechanisms of Cognitive Control * Project 5: Interactive Processes in Perception: Neurophysiology of Figure-Ground Organization * Project 6: Basic Mechanisms and Cooperating Systems in Learning Memory * Project 7: Age and Experience Dependent Processes in Learning * Project 8: Theoretical Foundations * Core: Integration, Computational Resources, and Administration | human, cognition, cognition, neural mechanism, learning, interdisciplinary, behavioral, semantic knowledge, language processing, cognitive control, perception, memory, learning, processing, representation, cognitive development, model development, brain damage, functional brain imaging | has parent organization: Carnegie Mellon University; Pennsylvania; USA | Normal cognition, Disordered cognition | NIMH | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-10757 | SCR_008085 | 2026-08-03 09:33:53 | 0 |
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