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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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Proteon Therapeutics Resource Report Resource Website 1+ mentions |
Proteon Therapeutics (RRID:SCR_004037) | Proteon | commercial organization | A biopharmaceutical company developing pharmaceuticals for patients with renal and vascular diseases. Their ongoing Phase 3 clinical trial is evaluating whether a single treatment of PRT-201 can reduce vascular access failure, one of the most serious problems experienced by patients with chronic kidney disease (CKD) undergoing hemodialysis. PRT-201 is an investigational drug that may inhibit neointimal hyperplasia, the growth of tissue inside blood vessels that can result in vessel narrowing and reduced blood flow. PRT-201 has received fast track and orphan drug designations for hemodialysis vascular access indications.In September 2019, Proteon Therapeutics merged with ArTara Therapeutics. | biopharmaceutical, pharmaceutical, hemodialysis, prt-201, drug |
is related to: Kidney Health Initiative is related to: Protara Therapeutics |
Kidney disease, Vascular disease, Chronic kidney disease, Neointimal hyperplasia, Peripheral arterial disease | nlx_158465 | SCR_004037 | Proteon Therapeutics Inc. | 2025-02-14 10:30:47 | 1 | |||||||
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Thrasos Therapeutics Resource Report Resource Website |
Thrasos Therapeutics (RRID:SCR_004052) | Thrasos | commercial organization | Private, clinical stage biotherapeutics company focused on delivering new solutions to individuals affected by kidney disease. They are committed to developing novel approaches to protect, treat and restore kidney function for this patient group. Company has designed specific class of peptide compounds that have shown excellent results in controlling experimental kidney diseases, notably, models of diabetic nephropathy (kidney damage associated with diabetes), and acute kidney injury. These proprietary peptides may therefore be able to prevent and treat acute kidney injury, as well as slow and possibly reverse the progression of diabetic nephropathy. They act to control apoptosis (programmed cell death), inflammation and fibrosis (formation of scar tissue). | Controlling experimental kidney diseases, biotherapeutics, clinical, peptide, treat acute kidney injury, reverse progression diabetic nephropathy | is related to: Kidney Health Initiative | Kidney disease, Acute kidney injury, Diabetic nephropathy, Chronic kidney disease | nlx_158489 | http://www.thrasos.com/ | SCR_004052 | Thrasos Innovation Inc. | 2025-02-14 10:30:16 | 0 | ||||||
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Nephropath Resource Report Resource Website 1+ mentions |
Nephropath (RRID:SCR_003995) | Nephropath | commercial organization | Commercial service interpreting renal biopsies using 14 board-certified, fellowship-trained pathologists with decades of experience. They provide doctors with a high quality, clinico-pathologic discussion by the pathologist that read the case. It is their goal to help equip doctors with the results they need to deliver the most effective patient care possible. That is why they deliver same-day biopsy results, including EM, because they know that time often has a critical effect on the outcome of many renal diseases. Nephropath also offers PLA2R serum testing and will soon be offering neuropathology services including muscle and nerve biopsy services.Nephropath is now Arkana Laboratories. | pathology, neuropathology, muscle, nerve, biopsy service, pathologist, kidney, biopsy, renal, serum, neurology | is related to: Kidney Health Initiative | Kidney disease | nlx_158408 | SCR_003995 | 2025-02-14 10:30:15 | 1 | ||||||||
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Arbor Research Collaborative for Health Resource Report Resource Website 1+ mentions |
Arbor Research Collaborative for Health (RRID:SCR_003972) | Arbor Research | nonprofit organization | A not-for-profit research organization committed to improve patient care through research that shapes medical policies and practice. In particular, they conduct health outcomes research on chronic disease and end-stage organ failure, with expertise in biostatistical analysis, clinical practice, health economics, public policy, database management and integration, and project coordination. Through research projects that are national and global in scope, their scientific collaborations provide valuable and timely information to the worldwide health care community. They are a leader in interdisciplinary health outcomes and policy research focused on reducing the health and economic burden of chronic diseases and improving the delivery of care. | health outcome, patient care, clinical, policy, nephrology, statistics, kidney, transplant, dialysis, epidemiology, public health, clinical practice, policy development, medical payment system | is related to: Kidney Health Initiative | Kidney disease, Organ failure, Chronic disease | grid.413857.c, nlx_158379, ISNI: 0000 0004 0628 9837 | https://ror.org/043qmbk61 | SCR_003972 | URREA, University Renal Research and Education Association | 2025-02-14 10:30:06 | 3 | ||||||
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American Nephrology Nurses Association Resource Report Resource Website 1+ mentions |
American Nephrology Nurses Association (RRID:SCR_003966) | ANNA | institution | Non-profit professional association that represents nurses who work in all areas of nephrology including hemodialysis, chronic kidney disease, peritoneal dialysis, acute care, and transplantation. Most members work in freestanding dialysis units, hospital outpatient units, and hospital inpatient units. ANNA develops and updates standards of clinical practice, educates practitioners, stimulates and supports research, disseminates knowledge and new ideas, promotes interdisciplinary communication and cooperation, and monitors and addresses issues encompassing the breadth of practice of nephrology nursing. | clinical, kidney, nephrology, nurse, health care, dialysis, journal, training resource |
is related to: Nephrology Nursing Certification Commission is related to: Kidney Health Initiative |
Kidney disease | grid.469735.a, nlx_158371, ISNI: 0000 0000 9310 7210, Crossref funder ID: 100005526 | https://ror.org/05a8c4g41 | SCR_003966 | American Nephrology Nurses'' Association | 2025-02-14 10:30:06 | 1 | ||||||
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NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases Resource Report Resource Website 100+ mentions |
NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases (RRID:SCR_012895) | NIDDK | government granting agency | Center with mission to conduct and support medical research and research training and to disseminate science-based information on diabetes and other endocrine and metabolic diseases. The NIDDK supports a wide range of medical research through grants to universities and other medical research institutions across the country. | diabetes, metabolic disease, digestive, kidney, endocrine, medical research |
recommends: Cell Image Library (CIL) recommends: Biological General Repository for Interaction Datasets (BioGRID) recommends: NIDDK Central Repository recommends: Accelerating Medicines Partnership Type 2 Diabetes Knowledge Portal (AMP-T2D) recommends: Metabolomics Workbench recommends: PeptideAtlas recommends: Network Data Exchange (NDEx) recommends: Mouse Genome Informatics (MGI) recommends: Zebrafish Information Network (ZFIN) recommends: FlyBase recommends: Database of Interacting Proteins (DIP) recommends: WormBase recommends: PhysioNet recommends: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) recommends: UniProt recommends: dbSNP recommends: DNA DataBank of Japan (DDBJ) recommends: European Nucleotide Archive (ENA) recommends: dbVar recommends: ClinicalTrials.gov recommends: European Variation Archive (EVA) recommends: MGnify recommends: Analysis, Visualization, and Informatics Lab-space (AnVIL) recommends: GenBank recommends: Gene Expression Omnibus (GEO) recommends: miRBase recommends: Database of Genomic Variants Archive (DGVa) recommends: Crystallography Open Database (COD) recommends: Coherent X-Ray Imaging Data Bank (CXIDB) recommends: Biological Magnetic Resonance Data Bank (BMRB) recommends: Worldwide Protein Data Bank (wwPDB) recommends: EMDataResource.org recommends: NCBI Assembly Archive Viewer recommends: Cambridge Crystallographic Data Centre (CCDC) recommends: Inorganic Crystal Structure Database (ICSD) recommends: Structural Biology Grid recommends: ArrayExpress recommends: GenomeRNAi recommends: NCBI database of Genotypes and Phenotypes (dbGap) recommends: Protein Circular Dichroism Data Bank (PCDDB) recommends: Electron Microscopy Data Bank at PDBe (MSD-EBI) recommends: PDBe - Protein Data Bank in Europe recommends: PubChem BioAssay recommends: Japanese Genotype-phenotype Archive (JGA) recommends: ProteomeXchange recommends: IntAct recommends: European Genome phenome Archive recommends: MetaboLights recommends: PubChem Substance recommends: The Immunology Database and Analysis Portal (ImmPort) recommends: STRENDA recommends: Kinetic Models of Biological Systems (KiMoSys) recommends: FLOWRepository recommends: Mass spectrometry Interactive Virtual Environment (MassIVE) recommends: Global Proteome Machine Database (GPM DB) recommends: Cancer Imaging Archive (TCIA) recommends: German Neuroinformatics Node (G-Node) recommends: 1000 Functional Connectomes Project recommends: ChEMBL recommends: Image Data Resource (IDR) recommends: SICAS Medical Image Repository recommends: ZENODO recommends: Dataverse Network Project recommends: NeuroMorpho.Org recommends: Mendeley Data recommends: NIMH Data Archive recommends: NIH Figshare Archive recommends: FigShare recommends: National Addiction and HIV Data Archive Program (NAHDAP) recommends: Dryad Digital Repository recommends: Open Science Framework recommends: OpenNeuro recommends: SPARC Project lists: Mutant Mouse Resource and Research Center lists: NIDDK Research Resources is affiliated with: Cystic Fibrosis Research and Translation Centers is affiliated with: Nutrition and Obesity Research Centers is affiliated with: O'Brien Urology Centers is affiliated with: Hematology Centers is affiliated with: Polycystic Kidney Disease Research and Translation Centers is affiliated with: O'Brien Kidney Centers is affiliated with: Diabetes Research Centers is affiliated with: Digestive Disease Centers is affiliated with: Centers for Diabetes Translation Research is affiliated with: Pediatric Centers of Excellence in Nephrology is affiliated with: Focal Segmental Glomerulosclerosis in Children and Young Adults Interventional Study is related to: Bridging Interventional Development Gaps is related to: Polycystic Kidney Disease Research Resource Consortium has parent organization: National Institutes of Health is parent organization of: MTOPS Prostate Samples Analysis Consortium is parent organization of: Symptom Score for Benign Prostatic Hyperplasia is parent organization of: Type 1 Diabetes - Rapid Access to Intervention Development is parent organization of: National Diabetes Education Program is parent organization of: Family Investigation of Nephropathy of Diabetes is parent organization of: Frequent Hemodialysis Network Daily Trial is parent organization of: HemBase is parent organization of: NIDDK- National Institute of Diabetes and Digestive and Kidney Diseases Obesity Resources is parent organization of: dkCOIN is parent organization of: National Kidney Disease Education Program is parent organization of: Network of Minority Health Research Investigators is parent organization of: National Endocrine and Metabolic Diseases Information Service is parent organization of: National Diabetes Information Clearinghouse is parent organization of: National Digestive Diseases Information Clearinghouse is parent organization of: National Hematologic Diseases Information Service is parent organization of: National Kidney and Urologic Diseases Information Clearinghouse is parent organization of: Type 1 Diabetes Preclinical Testing Program is parent organization of: Frequent Hemodialysis Network Nocturnal Trial is parent organization of: Boston Area Community Health Survey is parent organization of: Minimally Invasive Surgical Therapies Treatment Consortium for Benign Prostatic Hyperplasia is parent organization of: Focal Segmental Glomerulosclerosis in Children and Young Adults Interventional Study |
Type 1 diabetes, Type 2 diabetes, Diabetes, Digestive disease, Kidney disease, Endocrine disease, Obesity, Blood disease, Liver disease, Urologic disease | nlx_inv_1005102 | SCR_012895 | National Institute of Diabetes and Digestive and Kidney Diseases | 2025-02-14 10:32:19 | 132 | |||||||
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George Institute for Global Health Resource Report Resource Website 1+ mentions |
George Institute for Global Health (RRID:SCR_011212) | George Institute | institution | An independent medical research institute dedicated to improving global health that conducts high impact research that targets preventable illnesses and injuries that are the leading causes of death and disability worldwide, including heart and kidney disease, stroke, diabetes, mental illness, falls and traffic crashes. (Adapted from Wikipedia) | is related to: Kidney Health Initiative | Heart disease, Kidney disease, Stroke, Diabetes, Mental illness, Fall, Traffic crash | nlx_158485, grid.452860.d | https://ror.org/05e1zqb39 | SCR_011212 | The George Institute for Global Health | 2025-02-14 10:32:04 | 2 | |||||||
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NIDDK Research Resources Resource Report Resource Website |
NIDDK Research Resources (RRID:SCR_014372) | data or information resource, database | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 29,2023. Registry listing NIDDK resources, such as reagents, data, and protocols. They are derived from publicly available information provided by NIDDK-funded investigators, projects, and publications. | research, registry, diabetes, kidney disease, reagent, data, protocol |
lists: NIDDK Information Network (dkNET) lists: Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study (ACCORDION) lists: Predicting Response to Standardized Pediatric Colitis Therapy (PROTECT) lists: Lifestyle Interventions for Expectant Moms (LIFE-Moms) lists: Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium (HAPO-FUS) lists: Nephrotic Syndrome Study Network (NEPTUNE) lists: CKD Biomarkers Consortium lists: Porphyria Consortium lists: Vitamin D to Prevent Type 2 Diabetes (D2d) lists: Glycemic Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) lists: Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) lists: Clinical Islet Transplantation Consortium (CITC) lists: Restoring Insulin Secretion Consortium (RISE) lists: Assessment Serial Evaluation and Subsequent Sequelae in Acute Kidney Injury (ASSESS-AKI) lists: Integrated Islet Distribution Program (IIDP) lists: Rare Kidney Stone Consortium (RKSC) lists: Evaluating Predictors and Interventions in Sphincter of Oddi Dysfunction lists: Efficacy and Mechanisms of Glutamine Dipeptide in the Surgical Intensive Care Unit lists: Intestinal Stem Cell Consortium lists: RiVuR lists: Gastroparesis Clinical Research Consortium lists: Urologic Diseases in America lists: United States Renal Data System lists: HALT PKD lists: Chronic Renal Insufficiency Cohort Study lists: HEALTHY study lists: Viral Resistance to Antiviral Therapy of Chronic Hepatitis C lists: Peginterferon and Ribavirin for Pediatric Patients with Chronic Hepatitis C lists: HALT-C Trial lists: TRIGR lists: Treatment Options for type 2 Diabetes in Adolescents and Youth lists: Study of Nutrition in Acute Pancreatitis lists: SEARCH for Diabetes in Youth lists: Organ Procurement and Transplantation Network lists: Nuclear Receptor Signaling Atlas lists: NIH Common Fund lists: Mutant Mouse Resource and Research Center lists: GenitoUrinary Development Molecular Anatomy Project lists: National Mouse Metabolic Phenotyping Centers lists: IPD-MHC- Major Histocompatibility Complex lists: High-dose Ursodiol Therapy of Primary Sclerosing Cholangitis lists: Hepatitis B Research Network lists: Functional Dyspepsia Treatment Trial lists: Cooperative Study Group for Autoimmune Disease Prevention lists: Clinical Outcomes Research Initiative lists: BISC lists: The Immunology Database and Analysis Portal (ImmPort) lists: Beta Cell Biology Consortium lists: Autoimmunity Centers of Excellence lists: HemBase lists: Longitudinal Assessment of Bariatric Surgery lists: Minnesota Liver Tissue Cell Distribution System lists: Knockout Mouse Project lists: Immune Tolerance Network (ITN) lists: Multi-Disciplinary Approach to the Study of Chronic Pelvic Pain is listed by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases |
Diabetes, Kidney disease | THIS RESOURCE IS NO LONGER IN SERVICE | SCR_014372 | National Institute of Diabetes and Digestive and Kidney Diseases Research Resources | 2025-03-30 11:12:39 | 0 | ||||||||
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Nephromine Resource Report Resource Website 10+ mentions |
Nephromine (RRID:SCR_003813) | data or information resource, database | THIS RESOURCE IS NO LONGER IN SERVICE; REPLACED BY NEPHROSEQ; A growing database of publicly available renal gene expression profiles, a sophisticated analysis engine, and a powerful web application designed for data mining and visualization of gene expression. It provides unique access to datasets from the Personalized Molecular Nephrology Research Laboratory incorporating clinical data which is often difficult to collect from public sources and mouse data. | kidney, gene expression, visualization, clinical, expression profile, gene, mouse model, microarray |
is listed by: NIDDK Information Network (dkNET) is related to: Nephroseq has parent organization: University of Michigan; Ann Arbor; USA has parent organization: Life Technologies |
Kidney disease, Healthy, Lupus nephritis, Chronic kidney disease, Diabetic nephropathy | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_158114 | SCR_003813 | 2025-03-30 11:03:37 | 20 | ||||||||
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National Renal Administrators Association Resource Report Resource Website |
National Renal Administrators Association (RRID:SCR_003991) | NRAA | community building portal, data or information resource, portal | A nonprofit organization representing dialysis facilities and centers throughout the United States. It supports members from all types of providers including freestanding, hospital-based and national chains through the weekly e-mail newsletter, Renal Watch, the Annual Meeting, periodic workshops and other meetings. NRAA members include dialysis provider companies and management consulting companies and other companies involved in the End Stage Renal Disease (ESRD) industry and supportive of the purposes of NRAA. Individuals not directly employed or otherwise involved in companies that are NRAA members may join as individual Associate Members. The purposes for which the NRAA is organized are as follows: # To provide renal administrators the opportunity for gaining continuing education, obtaining peer recognition and expanding development in the profession. # To promote and encourage education and training for renal administrators. # To recognize individuals who have done or are doing noteworthy service in the field of renal administration. # To educate the public and members of governing bodies of health care organizations to understand the issues surrounding the practice of renal administration. # To represent the professional interests of renal administrators as a national representative spokesperson for the development and implementation of public policy. # To act as a resource on local and national ESRD issues. | kidney, dialysis | is related to: Kidney Health Initiative | Kidney disease, End Stage Renal Disease | nlx_158405 | SCR_003991 | 2025-04-01 11:03:36 | 0 | ||||||||
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Nephrology Nursing Certification Commission Resource Report Resource Website |
Nephrology Nursing Certification Commission (RRID:SCR_003994) | NNCC | training resource, data or information resource, portal, organization portal | Organization that established credentialing mechanisms to promote patient safety and to improve the quality of care provided to nephrology patients. There is a diversity of examinations providing the opportunity for certification at various levels of education, experience, and areas of practice within nephrology nursing. All of the certification examinations are endorsed by American Nephrology Nurses'''' Association (ANNA). The Commission recognizes the value of education, administration, research, and clinical practice in fostering personal and professional growth and currently provides six examinations to validate clinical performance: * The Certified Dialysis Nurse examination * The Certified Dialysis LPN/LVN examination * The Certified Nephrology Nurse examination * The Certified Clinical Hemodialysis Technician * The Certified Clinical Hemodialysis Technician - Advanced * The Certified Nephrology Nurse - Nurse Practitioner | nephrology, kidney, nursing, certification, clinical, dialysis, hemodialysis |
is related to: American Nephrology Nurses Association is related to: Kidney Health Initiative |
Kidney disease | nlx_158407 | SCR_003994 | Nephrology Nursing Certification Board, NNCB | 2025-04-01 11:03:37 | 0 | |||||||
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NephCure Kidney International Resource Report Resource Website 1+ mentions |
NephCure Kidney International (RRID:SCR_003993) | NephCure | topical portal, funding resource, disease-related portal, data or information resource, portal | Nonprofit organization committed exclusively to support research seeking the cause of the potentially debilitating kidney disease Focal Segmental Glomerulosclerosis (FSGS) and Nephrotic Syndrome, improve treatment and find a cure. NephCure Kidney International is: * Committed to funding research around the globe that will continue to move us closer to an improved treatment and a cure. * The primary source of information on Nephrotic Syndrome and FSGS. * Leading the charge for legislative action to provide more federal funding for research into Nephrotic Syndrome and FSGS. * Working to attract researchers to this field. * Educating the public and raising awareness about Nephrotic Syndrome and FSGS. | kidney | is related to: Kidney Health Initiative | Nephrotic Syndrome, Focal Segmental Glomerulosclerosis, Kidney disease | nlx_158406 | SCR_003993 | NephCure Foundation | 2025-04-01 11:03:37 | 1 | |||||||
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ERA-EDTA Resource Report Resource Website 10+ mentions |
ERA-EDTA (RRID:SCR_003982) | ERA-EDTA | community building portal, data or information resource, portal | An association of European kidney specialists whose objective is advancement of medical science and of clinical work in nephrology, dialysis, renal transplantation, hypertension and related subjects. They aim at providing up-to-date knowledge, exclusively based on scientific data, independent from governments'' policies and from any influence of the industry. It is registered in England and Wales, but its area of activity mainly covers Europe and the Mediterranean area. | kidney, dialysis, transplant, nephrology, medical, clinical, renal transplantation, hypertension | is related to: Kidney Health Initiative | Kidney disease | nlx_158389 | SCR_003982 | European Renal Association - European Dialysis and Transplant Association, European Renal Association - European Dialysis & Transplant Association | 2025-04-01 11:03:36 | 22 | |||||||
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American Association of Kidney Patients Resource Report Resource Website 1+ mentions |
American Association of Kidney Patients (RRID:SCR_003965) | AAKP | topical portal, disease-related portal, data or information resource, portal, patient-support portal | Association of kidney patients focused on patient-centered education, advocacy and community. They share educational pieces covering every level of kidney disease, advocate for improved access to high-quality health care through regulatory and legislative reform at the federal level, and make an effort to bring kidney patients together to promote community, conversations and to seek out services that help maximize patients'' everyday lives. | kidney, dialysis | is related to: Kidney Health Initiative | Kidney disease | nlx_158369 | SCR_003965 | 2025-04-01 11:03:35 | 1 | ||||||||
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Jackson Heart Study Resource Report Resource Website 50+ mentions |
Jackson Heart Study (RRID:SCR_009902) | service resource, access service resource, core facility | The JHS is the largest single-site longitudinal, population-based, cohort study of 5,302 persons initiated in the fall of 2000 to prospectively investigate the determinants of CVD among African Americans in the Jackson, MS metropolitan statistical area. The JHS investigates the various genotype and phenotype factors that affect high blood pressure, heart disease, strokes, diabetes and other important diseases in African Americans. The primary objective of the Jackson Heart Study is to investigate the causes of cardiovascular disease (CVD) in African Americans to learn how to best prevent this group of diseases in the future. More specific objectives include: 1. Identification of factors, which influence the development, and worsening of CVD in African Americans, with an emphasis on manifestations related to high blood pressure (such as remodeling of the left ventricle of the heart, coronary artery disease, heart failure, stroke and disorders affecting the blood vessels of the kidney). 2. Building research capabilities in minority institutions at the undergraduate and graduate level by developing partnerships between minority and majority institutions and enhancing participation of minority investigators in large-scale epidemiologic studies. 3. Attracting minority students to and preparing them for careers in health sciences. |
is listed by: Eagle I is related to: A Whole Genome Admixture Scan for Type 2 Diabetes in African Americans has parent organization: Jackson State University; Mississippi; USA |
Diabetes, Cardiovascular disease, Kidney disease, Respiratory disease | nlx_156367 | SCR_009902 | 2025-04-01 11:08:52 | 70 | ||||||||||
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Genetics of Kidneys in Diabetes Resource Report Resource Website |
Genetics of Kidneys in Diabetes (RRID:SCR_000133) | GoKinD, Go KinD | material resource, biomaterial supply resource | Collect, store, and distribute genetic samples from cases and controls of type 1 diabetes and diabetic nephropathy for investigator-driven research into the genetic basis of diabetic nephropathy. As the risk of kidney complications in type 1 diabetes appears to have a considerable genetic component, this study assembled a large data resource for researchers attempting to identify causative genetic variants. The types of data collected allowed traditional case-control testing, a rapid and often powerful approach, and family-based analysis, a robust approach that is not influenced by population substructure. To identify genes that are involved in diabetic nephropathy, a large number of individuals with type 1 diabetes were screened to identify two subsets, one with clear-cut kidney disease and another with normal renal status despite long-term diabetes. Those who met additional entry criteria and consented to participate were enrolled. When possible, both parents also were enrolled to form family trios. As of November 2005, GoKinD included 3075 participants who comprise 671 case singletons, 623 control singletons, 272 case trios, and 323 control trios. Interested investigators may request the DNA collection and corresponding clinical data for GoKinD participants. Participating scientists will have access to three data sets, each with distinct advantages. The set of 1294 singletons has adequate power to detect a wide range of genetic effects, even those of modest size. The set of case trios, which has adequate power to detect effects of moderate size, is not susceptible to false-positive results because of population substructure. The set of control trios is critical for excluding certain false-positive results that can occur in case trios and may be particularly useful for testing gene-environment interactions. Integration of the evidence from these three components into a single, unified analysis presents a challenge. This overview of the GoKinD study examines in detail the power of each study component and discusses analytic challenges that investigators will face in using this resource. Half of the samples were collected at the Joslin Diabetes Center and the other half were collected from around the country by researchers at The George Washington University. DNA samples were processed by scientists at the University of Minnesota and stored at the U.S. Centers for Disease Control and Prevention. Stored samples were available to the research community through a mechanism that has been determined by JDF. Clinical characteristics of patients, which are stored in a central database, are also made available to participating scientists. A similar collection is being carried out in the United Kingdom. This data resource allows researchers to test hypotheses that might explain why diabetic kidney disease clusters in families. This resource also is suitable for studying other complications and type 1 diabetes itself. For example, a total of 1,110 diabetes case trios was available at the end of three years.) | clinical, genetics, genetic variant, gene, data set |
is listed by: One Mind Biospecimen Bank Listing is listed by: NIDDK Information Network (dkNET) has parent organization: George Washington University; Washington D.C.; USA |
Type 1 diabetes, Diabetes, Diabetic nephropathy, Kidney disease | JDRF ; NIH |
PMID:16775037 | To qualified researchers | nlx_152764 | http://www.gokind.org/access | SCR_000133 | Genetics of Kidneys in Diabetes (GoKinD) Study, Genetics of Kidneys in Diabetes Study | 2025-04-01 11:00:10 | 0 | |||
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George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Clinical and Translational Core Resource Report Resource Website |
George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Clinical and Translational Core (RRID:SCR_015295) | service resource, resource, access service resource, core facility | Core whose aim is to translate basic science research into effective diagnostic and therapeutic strategies that will improve the lives of patients by interrupting the pathogenesis of chronic kidney disease and its attendant high risk of cardiovascular disability and death. It combines comprehensive human genetics with phenotyping of subjects. | clinical, translational research, kidney disease, cardiovascular disease |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Texas Southwestern Medical Center; Texas; USA has parent organization: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center is organization facet of: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center |
kidney disease | NIDDK P30DK079328 | Available to the research community, Fee for service | SCR_015295 | 2025-04-01 11:12:38 | 0 | ||||||||
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Duke O'Brien Center for Kidney Research Renal Genomics Core Resource Report Resource Website |
Duke O'Brien Center for Kidney Research Renal Genomics Core (RRID:SCR_015269) | service resource, resource, access service resource, core facility | Core facility that provides resources for investigators researching the genetic mechanisms of chronic kidney disease, cardiovascular disease, and hypertension. Its services include pre-study consultation, standardized services for DNA isolation and storage, and assisstance in carrying out molecular genetic studies. | chronic kidney disease research service, cardiovascular disease research service, hypertensions research service, experimental consultation |
is listed by: NIDDK Information Network (dkNET) has parent organization: Duke O'Brien Center for Kidney Research has parent organization: Duke University School of Medicine; North Carolina; USA has parent organization: Duke University; North Carolina; USA is organization facet of: Duke O'Brien Center for Kidney Research |
kidney disease, heart disease, hypertension, muscle disease | NIDDK P30DK096493 | Available to the research community | SCR_015269 | 2025-04-01 11:12:35 | 0 | ||||||||
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Duke O'Brien Center for Kidney Research Clinical and Translational Core Resource Report Resource Website |
Duke O'Brien Center for Kidney Research Clinical and Translational Core (RRID:SCR_015272) | service resource, resource, access service resource, core facility | Core facility which investigates the connections between chronic kidney disease, cardiovascular disease, and hypertension. It focuses specifically on investigating the pathophysiology, epidemiology, and therapeutic response in on-going studies or existing datasets of one of the three diseases with the aim of relating data from individual diseases to each other. | translational kidney research, translational cardiovascular research, translational hypertension research |
is listed by: NIDDK Information Network (dkNET) has parent organization: Duke O'Brien Center for Kidney Research has parent organization: Duke University School of Medicine; North Carolina; USA has parent organization: Duke University; North Carolina; USA is organization facet of: Duke O'Brien Center for Kidney Research |
kidney disease, heart disease, hypertension, muscle disease | NIDDK P30DK096493 | Available to the research community | SCR_015272 | 2025-04-01 11:12:36 | 0 | ||||||||
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Hematology Centers Resource Report Resource Website |
Hematology Centers (RRID:SCR_015321) | topical portal, disease-related portal, data or information resource, portal, resource, organization portal | Online portal with thorough information about hematology research centers and cores. Each entry details the center's research aims, its activities and core services, and links to pilot programs. | hematology research, online portal, research aims, niddk |
is listed by: NIDDK Information Network (dkNET) is affiliated with: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases has organization facet: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology has organization facet: Center for Iron and Heme Disorders at the University of Utah has organization facet: Indiana University Cooperative Center of Excellence in Hematology has organization facet: Yale Cooperative Center of Excellence in Hematology has organization facet: Boston Children's Hospital Center of Excellence in Molecular Hematology |
Diabetes, digestive disease, kidney disease | NIDDK U54 RFA-DK15-021 | Available to the research community | SCR_015321 | 2025-04-01 11:12:41 | 0 |
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