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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
GMcloser
 
Resource Report
Resource Website
1+ mentions
GMcloser (RRID:SCR_000646) GMcloser software resource Software that fills and closes the gaps present in scaffold assemblies, especially those generated by the de novo assembly of whole genomes with next-generation sequencing (NGS) reads. Unlike other gap-closing tools that use only NGS reads, GMcloser uses preassembled contig sets or long read sets as the sequences to close gaps and uses paired-end (PE) reads and a likelihood-based algorithm to improve the accuracy and efficiency of gap closure. The efficiency of gap closure can be increased by successive treatments with different contig sets. scaffolding, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:26261222 Free, Available for download, Freely available biotools:gmcloser, OMICS_00042 https://bio.tools/gmcloser SCR_000646 Gmcloser - Closing the gaps in scaffolds with preassembled contigs 2026-08-01 12:01:22 3
clipcrop
 
Resource Report
Resource Website
clipcrop (RRID:SCR_000678) software resource Software tool for detecting structural variations with single-base resolution using soft-clipping information from SAM files. structural variation, detecting structural variations, soft-clipping information, SAM files, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:22373054 Free, Available for download, Freely available biotools:clipcrop, OMICS_00310 https://bio.tools/clipcrop SCR_000678 ClipCrop 2026-08-01 12:01:23 0
TriageTools
 
Resource Report
Resource Website
TriageTools (RRID:SCR_000675) TriageTools software resource A collection of tools for partitioning raw data (fastq reads) from high-throughput sequencing projects. The tools are designed for basic data management as well for prioritizing analysis of certain subsets. matlab, java, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:23408855 Free, Available for download, Freely available biotools:triagetools, nlx_156740 https://bio.tools/triagetools SCR_000675 2026-08-01 12:01:17 0
Opera
 
Resource Report
Resource Website
1+ mentions
Opera (RRID:SCR_000665) software resource A sequence assembly software program that uses information from paired-end reads to optimally order and orient contigs assembled from shotgun-sequencing reads. sequence assembly, paired-end, orient contigs, shotgun-sequencing, shotgun, software program, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:27169502
PMID:21929371
Free, Available for download, Freely available biotools:opera, OMICS_00045 https://bio.tools/opera SCR_000665 OPERA-LG, Optimal Paired-End Read Assembler 2026-08-01 12:01:27 3
pFind Studio: pLink
 
Resource Report
Resource Website
10+ mentions
pFind Studio: pLink (RRID:SCR_000084) pLink software resource Software dedicated for the analysis of chemically cross-linked proteins or protein complexes using mass spectrometry., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. mass spectrometry, proteomics, pFind Studio, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Chinese Academy of Sciences; Beijing; China
PMID:22772728 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02404, biotools:pLink-2 https://github.com/pFindStudio/pLink3/releases http://pfind.ict.ac.cn/software/pLink/index.html SCR_000084 , pLink, pLink (pFind Studio), pLink2 2026-08-01 12:01:09 15
GUARDD
 
Resource Report
Resource Website
GUARDD (RRID:SCR_000040) software resource MATLAB software designed to organize, automate, and enhance the analytical procedures which operate on CPMG RD NMR data. standalone software, matlab, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Google Code
PMID:22160811 Free, Available for download, Freely available biotools:guardd, OMICS_04020 https://bio.tools/guardd SCR_000040 Graphical User-friendly Analysis of Relaxation Dispersion Data 2026-08-01 12:01:07 0
FACS
 
Resource Report
Resource Website
1+ mentions
FACS (RRID:SCR_000055) FACS software resource Software for classification of Sequences using Bloom filters that can accurately and rapidly align sequences to a reference sequence. unix/linux, sequence, bio.tools is listed by: OMICtools
is listed by: GitHub
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: SciLifeLab
PMID:20472541 Free, Available for download, Freely available OMICS_02147, biotools:facs https://bio.tools/facs SCR_000055 Fast and Accurate Classification of Sequences 2026-08-01 12:01:08 5
GEOquery
 
Resource Report
Resource Website
10+ mentions
GEOquery (RRID:SCR_000146) GEOquery software resource Software that establishes a bridge between GEO and BioConductor. microarray, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Expression Omnibus
is related to: GEO2R
has parent organization: Bioconductor
has parent organization: National Institutes of Health
PMID:17496320 Free, Available for download, Freely available biotools:geoquery, OMICS_01972 https://bio.tools/geoquery, https://sources.debian.org/src/r-bioc-geoquery/ SCR_000146 GEOquery - Get data from NCBI Gene Expression Omnibus (GEO) 2026-08-01 12:01:11 18
GemSIM
 
Resource Report
Resource Website
GemSIM (RRID:SCR_000167) GemSIM software resource A software package for generating realistic simulated next-generation genome sequencing reads with quality score values. The software is written in Python with a command-line user interface. bioinformatics, simulation, sequencing, dna, rna, empirical models, Python, command-line, user interface, metagenomic, resequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
is required by: Wessim
PMID:22336055
DOI:10.1186/1471-2164-13-74
Free, Available for download, Freely available OMICS_01507, biotools:GemSIM https://bio.tools/GemSIM SCR_000167 2026-08-01 12:01:12 0
MIMOSA
 
Resource Report
Resource Website
MIMOSA (RRID:SCR_000184) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Software for modeling count data using Dirichlet-multinomial and beta-binomial mixtures with applications to single-cell assays. software package, mac os x, unix/linux, windows, r, cell based assay, flow cytometry, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23887981 THIS RESOURCE IS NO LONGER IN SERVICE biotools:mimosa, OMICS_05642 https://bio.tools/mimosa SCR_000184 MIMOSA - Mixture Models for Single-Cell Assays, MIMOSA: Mixture Models For Single Cell Assays 2026-08-01 12:01:09 0
MODENT - A Tool For Reconstructing Gene Regulatory Networks
 
Resource Report
Resource Website
1+ mentions
MODENT - A Tool For Reconstructing Gene Regulatory Networks (RRID:SCR_000220) ModEnt software resource A computational tool that reconstructs gene regulatory networks from high throughput experimental data. gene regulatory network, experimental data, computation, computational tool, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Tel Aviv University; Ramat Aviv; Israel
PMID:22216865 Free, Available for download, Freely available biotools:modent, OMICS_01685 https://bio.tools/modent SCR_000220 2026-08-01 12:01:09 1
GENIE3
 
Resource Report
Resource Website
10+ mentions
GENIE3 (RRID:SCR_000217) GENIE3 software resource An algorithm for the inference of gene regulatory networks from expression data. javascript, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:20927193 Free, Available for download, Freely available biotools:genie3, OMICS_01683 https://bio.tools/genie3 http://www.montefiore.ulg.ac.be/~huynh-thu/software.html SCR_000217 2026-08-01 12:01:09 10
GraBCas
 
Resource Report
Resource Website
GraBCas (RRID:SCR_000205) GraBCas software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. A software tool for predicting granzyme B and caspase cleavage sites. matlab, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:15980455 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01674, biotools:grabcas https://bio.tools/grabcas SCR_000205 2026-08-01 12:01:13 0
deepSNV
 
Resource Report
Resource Website
10+ mentions
deepSNV (RRID:SCR_006214) deepSNV software resource Software package that provides quantitative variant callers for detecting subclonal mutations in ultra-deep (>=100x coverage) sequencing experiments. The algorithm is used for a comparative setup with a control experiment of the same loci and uses a beta-binomial model and a likelihood ratio test to discriminate sequencing errors and subclonal SNVs (single nucleotide variants). data import, genetic variability, genetics, snp, sequencing, single nucleotide variant, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24443148 GNU General Public License, v3 OMICS_02239, biotools:deepsnv https://bio.tools/deepsnv SCR_006214 deepSNV - Detection of subclonal SNVs in deep sequencing experiments 2026-08-01 12:03:05 34
QCGWAS
 
Resource Report
Resource Website
1+ mentions
QCGWAS (RRID:SCR_006408) QCGWAS software resource Software tools for (automated and manual) quality control of the results of Genome Wide Association Studies. quality control, genome wide association study, windows, os x, r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:24395754 GNU General Public License, v3 or later OMICS_02203, biotools:qcgwas https://bio.tools/qcgwas SCR_006408 QCGWAS: Quality Control of Genome Wide Association Study results, Quality Control of Genome Wide Association Study 2026-08-01 12:03:09 7
Jalview
 
Resource Report
Resource Website
1000+ mentions
Jalview (RRID:SCR_006459) Jalview software resource A free program for multiple sequence alignment editing, visualisation and analysis that is available in two forms: a lightweight Java applet for use in web applications, and a powerful desktop application that employs web services for sequence alignment, secondary structure prediction and the retrieval of alignments, sequences, annotation and structures from public databases and any DAS 1.53 compliant sequence or annotation server. Use it to view and edit sequence alignments, analyse them with phylogenetic trees and principal components analysis (PCA) plots and explore molecular structures and annotation. Jalview has built in DNA, RNA and protein sequence and structure visualisation and analysis capabilities. It uses Jmol to view 3D structures, and VARNA to display RNA secondary structure. edit, analysis, annotation, multiple sequence alignment, wysiwyg, bio.tools, FASEB list is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: University of Dundee; Scotland; United Kingdom
BBSRC BBSB16542 PMID:19151095
DOI:10.1093/bioinformatics/btp033
GNU General Public License, v3, Acknowledgement requested OMICS_00885, biotools:Jalview https://bio.tools/Jalview, https://sources.debian.org/src/jalview/ SCR_006459 2026-08-01 12:03:10 3769
SRAdb
 
Resource Report
Resource Website
10+ mentions
SRAdb (RRID:SCR_006524) SRAdb software resource Software package to make access to the compilation of metadata from NCBI SRA and tools associated with submission, study, sample, experiment and run much more feasible. This is accomplished by parsing all the NCBI SRA metadata into a SQLite database that can be stored and queried locally. Fulltext search in the package make querying metadata very flexible and powerful. fastq and sra files can be downloaded for doing alignment locally. Beside ftp protocol, the SRAdb has funcitons supporting fastp protocol (ascp from Aspera Connect) for faster downloading large data files over long distance. The SQLite database is updated regularly as new data is added to SRA and can be downloaded at will for the most up-to-date metadata. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: NCBI Sequence Read Archive (SRA)
has parent organization: Bioconductor
PMID:23323543 Artistic License, v2 biotools:sradb, OMICS_01032 https://bio.tools/sradb SCR_006524 SRAdb - A compilation of metadata from NCBI SRA and tools 2026-08-01 12:03:09 18
NCBI
 
Resource Report
Resource Website
10000+ mentions
NCBI (RRID:SCR_006472) NCBI nonprofit organization A portal to biomedical and genomic information. NCBI creates public databases, conducts research in computational biology, develops software tools for analyzing genome data, and disseminates biomedical information for the better understanding of molecular processes affecting human health and disease. biomedical, genomic, molecular biology, health, disease, database, computational biology, bio.tools is used by: NIF Data Federation
is listed by: NIDDK Information Network (dkNET)
is listed by: bio.tools
is listed by: Debian
is related to: AmiGO
is related to: NCBI Viral Genomes
is related to: Clone DB
is related to: PubReader
is related to: OMIA - Online Mendelian Inheritance in Animals
is related to: European Nucleotide Archive (ENA)
is related to: Plant Co-expression Annotation Resource
is related to: METAGENOTE
is related to: Phyutility
is related to: CaspBase
is related to: Prokaryotic Genomes Automatic Annotation Pipeline
has parent organization: National Library of Medicine
is parent organization of: MedGen
is parent organization of: dbSTS
is parent organization of: PubMed Health
is parent organization of: BLASTP
is parent organization of: GQuery
is parent organization of: BLASTN
is parent organization of: GTEx eQTL Browser
is parent organization of: BLASTX
is parent organization of: Homology Maps Page
is parent organization of: PEDHUNTER
is parent organization of: Conserved Domain Database
is parent organization of: NCBI Genome Survey Sequences Database
is parent organization of: High Throughput Genomic Sequences Division
is parent organization of: AceView
is parent organization of: dbMHC
is parent organization of: dbSNP
is parent organization of: Entrez Gene
is parent organization of: NCBI Genome
is parent organization of: NCBI database of Genotypes and Phenotypes (dbGap)
is parent organization of: GenBank
is parent organization of: International HapMap Project
is parent organization of: IgBLAST
is parent organization of: Lowes Syndrome Mutation Database
is parent organization of: HomoloGene
is parent organization of: Influenza Virus Resource
is parent organization of: Distant Regulatory Elements
is parent organization of: e-PCR
is parent organization of: MapViewer
is parent organization of: Primer-BLAST
is parent organization of: dbVar
is parent organization of: NCBI Taxonomy
is parent organization of: NCBI Protein Database
is parent organization of: Gene Reference into Function
is parent organization of: Protein Clusters
is parent organization of: RefSeq
is parent organization of: TPA
is parent organization of: GENSAT at NCBI - Gene Expression Nervous System Atlas
is parent organization of: COBALT: Constraint-based Multiple Alignment Tool
is parent organization of: PubMed Central
is parent organization of: UniLib
is parent organization of: NCBI Structure
is parent organization of: PubChem
is parent organization of: Anopheles gambiae (African malaria mosquito) genome view
is parent organization of: UniGene
is parent organization of: NLM Catalog
is parent organization of: Entrez GEO Profiles
is parent organization of: Nucleotide database
is parent organization of: NCBI BioSystems Database
is parent organization of: CBLAST
is parent organization of: NCBI BioProject
is parent organization of: NCBI Probe
is parent organization of: PubMed
is parent organization of: NCBI BioSample
is parent organization of: NCBI Nucleotide
is parent organization of: NCBI Structure: Cn3D
is parent organization of: NCBI BLAST
is parent organization of: IBIS: Inferred Biomolecular Interactions Server
is parent organization of: NCBI Sequence Read Archive (SRA)
is parent organization of: Gene Expression Omnibus (GEO)
is parent organization of: NCBI Popset
is parent organization of: PIE the search
is parent organization of: Genetic Testing Registry
is parent organization of: NCBI Resource List
is parent organization of: NCBI dbRBC
is parent organization of: NCBI YouTube Channel
is parent organization of: NCBI Epigenomics
is parent organization of: ClinVar
is parent organization of: Genome Reference Consortium
is parent organization of: GeneReviews
is parent organization of: Molecular Imaging and Contrast Agent Database
is parent organization of: Consensus CDS
is parent organization of: UniSTS
is parent organization of: HIV-1 Human Protein Interaction Database
is parent organization of: Assay Guidance Manual
is parent organization of: Bookshelf
is parent organization of: COG
is parent organization of: Gene Expression Omnibus
is parent organization of: Molecular Modelling DataBase
is parent organization of: Organelle Genome Resources
is parent organization of: SKY/M-FISH/CGH
is parent organization of: dbEST
is parent organization of: JournalReview.org
is parent organization of: NCBI GenBank via FTP
is parent organization of: PubChem Compound
is parent organization of: Molecular Modeling DataBase
is parent organization of: Vector Alignment Search Tool
is parent organization of: PubChem BioAssay
is parent organization of: NCBI Genome Workbench
is parent organization of: TBLASTN
is parent organization of: TBLASTX
is parent organization of: Mega BLAST
is parent organization of: Genetic Codes
is parent organization of: HIV-1, Human Protein Interaction Database
is parent organization of: PubReader
is parent organization of: PubChem Substance
is parent organization of: OMIA - Online Mendelian Inheritance in Animals
is parent organization of: OMIM
is parent organization of: 1000 Genomes: A Deep Catalog of Human Genetic Variation
is parent organization of: GeneTests
is parent organization of: NCBI Genome Survey Sequences Database
is parent organization of: MagicBlast
is parent organization of: RefSeq
is parent organization of: Sequin
is parent organization of: Batch Entrez
is parent organization of: Entrez
is parent organization of: tbl2asn
is parent organization of: Whole Genome Shotgun (WGS) Project
is parent organization of: Digital Differential Display (DDD)
is parent organization of: BLASTClust
is parent organization of: PASC
is parent organization of: Open Reading Frame Finder
is parent organization of: Genotyping
works with: Human Mouse Disease Connection
works with: A plasmid Editor
works with: Database of genes related to Repeat Expansion Diseases
Public, The community can contribute to this resource nif-0000-00139, biotools:ncbi_resources https://bio.tools/ncbi_resources http://www.ncbi.nih.gov/ SCR_006472 National Center for Biotechnology Information, NCBI - National Center for Biotechnology Information 2026-08-01 12:03:10 25993
casper
 
Resource Report
Resource Website
100+ mentions
casper (RRID:SCR_006613) casper software resource Software to infer alternative splicing from paired-end RNA-seq data. The model is based on counting paths across exons, rather than pairwise exon connections, and estimates the fragment size and start distributions non-parametrically, which improves estimation precision. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
GNU General Public License, v2 or greater biotools:casper, OMICS_01270 https://bio.tools/casper SCR_006613 casper - Characterization of Alternative Splicing based on Paired-End Reads, Characterization of Alternative Splicing based on Paired-End Reads 2026-08-01 12:03:13 149
SpliceTrap
 
Resource Report
Resource Website
10+ mentions
SpliceTrap (RRID:SCR_006728) SpliceTrap software resource A statistic tool for quantifying exon inclusion ratios in paired-end RNA-seq data, with broad applications for the study of alternative splicing. SpliceTrap approaches to exon inclusion level estimation as a Bayesian inference problem. For every exon it quantifies the extent to which it is included, skipped or subjected to size variations due to alternative 3?/5? splice sites or Intron Retention. In addition, SpliceTrap can quantify alternative splicing within a single cellular condition, with no need of a background set of reads. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
has parent organization: Cold Spring Harbor Laboratory
PMID:21896509 biotools:splicetrap, OMICS_01292 https://bio.tools/splicetrap SCR_006728 2026-08-01 12:03:18 16

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