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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SpliceGrapher
 
Resource Report
Resource Website
10+ mentions
SpliceGrapher (RRID:SCR_006657) SpliceGrapher software resource Software that predicts alternative splicing patterns and produces splice graphs that capture in a single structure the ways a gene''s exons may be assembled. It enhances gene models using evidence from next-generation sequencing and EST alignments. is listed by: OMICtools
has parent organization: SourceForge
PMID:22293517 OMICS_01266 SCR_006657 2026-08-01 12:03:14 22
Bycom
 
Resource Report
Resource Website
Bycom (RRID:SCR_000659) software resource A software which can perform methylcytosine calling from BS-seq (WGBS and RRBS), and permits either unmapped reads (FASTQ) or mapped reads (SAM/BAM) to be used as the input data. Certain SNPs (C>A/G) can also be selected in the output. methylcytosine, bs-seq, fastq, sam, bam, snps, snp, wgbs, rrbs, sorftw is listed by: OMICtools
has parent organization: SourceForge
PMID:25255082 Free, Available for download, Freely available OMICS_00594 SCR_000659 2026-08-01 12:08:11 0
BamView
 
Resource Report
Resource Website
10+ mentions
BamView (RRID:SCR_004207) BamView software resource, source code A free interactive display of read alignments in BAM data files that can be launched with Java Web Start or downloaded. This interactive Java application for visualizing the large amounts of data stored for sequence reads which are aligned against a reference genome sequence can be used in a number of contexts including SNP calling and structural annotation. It has been integrated into Artemis so that the reads can be viewed in the context of the nucleotide sequence and genomic features. The source code is available as part of the Artemis code which can be downloaded from GitHub. bam, next-generation sequencing, java, snp calling, structural annotation, macosx, unix, windows, visualize, analyze, sequence read, reference sequence, single nucleotide polymorphism, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:22253280
PMID:20071372
GNU General Public License biotools:bamview, OMICS_00878, nlx_22933 https://bio.tools/bamview SCR_004207 2026-08-03 09:32:23 21
OWL API
 
Resource Report
Resource Website
10+ mentions
OWL API (RRID:SCR_005734) OWL API software resource, source code The OWL API is a Java API and reference implementation for creating, manipulating and serializing OWL Ontologies. The latest version of the API is focused towards OWL 2. The OWLAPI underpins ontology browsing and editing tools and platforms such as SWOOP and Protege4. Note that this API, or any other OWL-based API, can be used without an integrated OWL parser if you download a pre-converted OWL file generated from OBO. See OBO Ontologies List for all OBO ontologies converted to OWL (we do not list the full complement of OWL-based APIs here, only those of direct relevance to GO). The OWL API includes the following components: * An API for OWL 2 and an efficient in-memory reference implementation * RDF/XML parser and writer * OWL/XML parser and writer * OWL Functional Syntax parser and writer * Turtle parser and writer * KRSS parser * OBO Flat file format parser * Reasoner interfaces for working with reasoners such as FaCT++, HermiT, Pellet and Racer Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible ontology, owl, api, java, software library, parser, writer is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: University of Manchester; Manchester; United Kingdom
has parent organization: SourceForge
Open unspecified license - Free for academic use; available under either the LGPL or Apache Licenses nlx_149195 SCR_005734 The OWL API, OWLAPI 2026-08-03 09:32:55 15
ALCHEMY
 
Resource Report
Resource Website
1+ mentions
ALCHEMY (RRID:SCR_005761) ALCHEMY software resource, source code ALCHEMY is a genotype calling algorithm for Affymetrix and Illumina products which is not based on clustering methods. Features include explicit handling of reduced heterozygosity due to inbreeding and accurate results with small sample sizes. ALCHEMY is a method for automated calling of diploid genotypes from raw intensity data produced by various high-throughput multiplexed SNP genotyping methods. It has been developed for and tested on Affymetrix GeneChip Arrays, Illumina GoldenGate, and Illumina Infinium based assays. Primary motivations for ALCHEMY''s development was the lack of available genotype calling methods which can perform well in the absence of heterozygous samples (due to panels of inbred lines being genotyped) or provide accurate calls with small sample batches. ALCHEMY differs from other genotype calling methods in that genotype inference is based on a parametric Bayesian model of the raw intensity data rather than a generalized clustering approach and the model incorporates population genetic principles such as Hardy-Weinberg equilibrium adjusted for inbreeding levels. ALCHEMY can simultaneously estimate individual sample inbreeding coefficients from the data and use them to improve statistical inference of diploid genotypes at individual SNPs. The main documentation for ALCHEMY is maintained on the sourceforge-hosted MediaWiki system. Features * Population genetic model based SNP genotype calling * Simultaneous estimation of per-sample inbreeding coefficients, allele frequencies, and genotypes * Bayesian model provides posterior probabilities of genotype correctness as quality measures * Growing number of scripts and supporting programs for validation of genotypes against control data and output reformating needs * Multithreaded program for parallel execution on multi-CPU/core systems * Non-clustering based methods can handle small sample sets for empirical optimization of sample preparation techniques and accurate calling of SNPs missing genotype classes ALCHEMY is written in C and developed on the GNU/Linux platform. It should compile on any current GNU/Linux distribution with the development packages for the GNU Scientific Library (gsl) and other development packages for standard system libraries. It may also compile and run on Mac OS X if gsl is installed. diploid, genotype, snp, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: Cornell University; New York; USA
NSF 0606461 PMID:20926420 GNU General Public License biotools:alchemy, nlx_149227 https://bio.tools/alchemy SCR_005761 ALCHEMY - An automated population genetic model driven SNP genotype calling method 2026-08-03 09:32:55 5
Neurofitter
 
Resource Report
Resource Website
1+ mentions
Neurofitter (RRID:SCR_005843) Neurofitter software resource, source code Neurofitter is software for parameter tuning of electrophysiological neuron models. It automatically searches for sets of parameters of neuron models that best fit available experimental data, and therefore acts as an interface between neuron simulators, like Neuron or Genesis, and optimization algorithms, like Particle Swarm Optimization, Evolutionary Strategies, etc. neuron, parameter, tuning, electrophysiology, model, neuron simulator, neuron model has parent organization: SourceForge
has parent organization: University of Antwerp; Antwerp; Belgium
has parent organization: Brandeis University; Massachusetts; USA
has parent organization: Okinawa Institute of Science and Technology
Okinawa Institute of Science and Technology PMID:18974796 GNU General Public License, v2 nlx_149366 SCR_005843 2026-08-03 09:32:48 1
OrChem
 
Resource Report
Resource Website
1+ mentions
OrChem (RRID:SCR_008865) OrChem software resource, source code OrChem is an extension for the Oracle 11G database that adds registration and indexing of chemical structures to support fast substructure and similarity searching. The cheminformatics functionality is provided by the Chemistry Development Kit. OrChem provides similarity searching with response times in the order of seconds for databases with millions of compounds, depending on a given similarity cut-off. For substructure searching, it can make use of multiple processor cores on today''s powerful database servers to provide fast response times in equally large data sets. OrChem is an Oracle chemistry plug-in using the Chemistry Development Kit (CDK). The CDK is an open source Java library for Chemoinformatics and Bioinformatics. OrChem is maintained by the chemoinformatics and metabolism team of the European Bioinformatics Institute. Oracle Data cartridges extend the capabilities of the Oracle server. For chemistry various commercial cartridges exist that facilitate searching and analyzing chemical data. OrChem also provides functionality like this, but is not a cartridge. It doesn''t need Oracle''s extensibility architecture because its Java components run as Java stored procedures inside the Oracle standard JVM (Aurora). OrChem is suitable for Oracle 11G and onwards. Starting with Oracle 11g release 1 (11.1) there is a just-in-time(JIT) compiler for Oracle JVM environment. A JIT compiler for Oracle JVM enables much faster execution because it manages the invalidation, recompilation, and storage of code without an external mechanism. This new Oracle feature makes Java classes perform better than before. oracle, chemistry, cdk, similarity search, chemical structure, cheminformatics, bioinformatics, plugin is listed by: 3DVC
has parent organization: SourceForge
has parent organization: European Bioinformatics Institute
PMID:20298521 GNU Lesser General Public License nlx_149252 SCR_008865 2026-08-03 09:34:14 1
ANDES
 
Resource Report
Resource Website
10+ mentions
ANDES (RRID:SCR_002791) data processing software, data analysis software, software resource, software application, software toolkit Software library and a suite of applications, written in Perl and R, for deep sequencing statistical analyses. deep sequencing, biomarker detection, statistical analysis, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:20633290 Free, Freely available, Available for download biotools:andes, OMICS_01119 https://bio.tools/andes SCR_002791 Statistical tools for the Analyses of Deep Sequencing (ANDES), Statistical tools for the Analyses of Deep Sequencing, Statistical tools for the ANalyses of Deep Sequencing 2026-08-04 09:40:44 25
Rainbow
 
Resource Report
Resource Website
10+ mentions
Rainbow (RRID:SCR_002724) data processing software, data analysis software, software resource, sequence analysis software, software application Software developed to provide an ultra-fast and memory-efficient solution to clustering and assembling short reads produced by RAD-seq. software, tool, clustering, assembling, short, read, restriction, site, DNA, sequence, analysis, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:22942077
DOI:10.1093/bioinformatics/bts482
Free, Freely available, Available for download SCR_015992, OMICS_03722, biotools:rainbow https://bio.tools/rainbow, https://sources.debian.org/src/bio-rainbow/ SCR_002724 RAD-seq: Restriction-site Associated DNA sequencing, Bio-rainbow, RAD-seq 2026-08-04 09:40:43 41
deFuse
 
Resource Report
Resource Website
50+ mentions
deFuse (RRID:SCR_003279) data processing software, data analysis software, software resource, sequence analysis software, software application, software toolkit Software package for gene fusion discovery using RNA-Seq data. It uses clusters of discordant paired end alignments to inform a split read alignment analysis for finding fusion boundaries. rna sequencing, gene fusion, paired end alignment, split read, fusion boundary, bio.tools uses: SAMTOOLS
uses: Bowtie
uses: BLAT
uses: GMAP
uses: R Project for Statistical Computing
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
British Columbia Cancer Foundation ;
Vancouver General Hospital Foundation ;
Genome Canada ;
Michael Smith Foundation for Health Research ;
Canadian Breast Cancer Foundation ;
Canadian Institutes of Health Research's Bioinformatics Training Program
PMID:21625565 Free, Available for download, Freely available biotools:defuse, OMICS_01345 https://sourceforge.net/projects/defuse/, http://compbio.bccrc.ca/software/defuse/, https://bio.tools/defuse http://sourceforge.net/apps/mediawiki/defuse/index.php?title=Main_Page SCR_003279 2026-08-04 09:40:52 95
Clinical Measurement Ontology
 
Resource Report
Resource Website
Clinical Measurement Ontology (RRID:SCR_003291) CMO ontology, data or information resource, controlled vocabulary An ontology designed to be used to standardize morphological and physiological measurement records generated from clinical and model organism research and health programs. obo, phenotype, clinical, measurement, morphology, physiology is listed by: SourceForge
is listed by: BioPortal
is listed by: OBO
has parent organization: Medical College of Wisconsin; Wisconsin; USA
PMID:22654893 Free, Freely available nlx_157364 http://sourceforge.net/projects/phenoonto/, ftp://rgd.mcw.edu/pub/ontology/clinical_measurement/clinical_measurement.obo SCR_003291 2026-08-04 09:40:52 0
Niftilib
 
Resource Report
Resource Website
1+ mentions
Niftilib (RRID:SCR_003355) Niftilib software toolkit, software resource, source code, software library Niftilib is a set of i/o libraries for reading and writing files in the nifti-1 data format. nifti-1 is a binary file format for storing medical image data, e.g. magnetic resonance image (MRI) and functional MRI (fMRI) brain images. Niftilib currently has C, Java, MATLAB, and Python libraries; we plan to add some MATLAB/mex interfaces to the C library in the not too distant future. Niftilib has been developed by members of the NIFTI DFWG and volunteers in the neuroimaging community and serves as a reference implementation of the nifti-1 file format. In addition to being a reference implementation, we hope it is also a useful i/o library. Niftilib code is released into the public domain, developers are encouraged to incorporate niftilib code into their applications, and, to contribute changes and enhancements to niftilib. Please contact us if you would like to contribute additonal functionality to the i/o library. image data, mri, fmri, brain image, image, brain, neuroimaging is related to: NIfTI Data Format Working Group
has parent organization: SourceForge
Free, Available for download, Freely available nif-0000-32011 SCR_003355 The Nifti Libraries, Nifti Libraries 2026-08-04 09:40:53 3
Measurement Method Ontology
 
Resource Report
Resource Website
Measurement Method Ontology (RRID:SCR_003373) MMO ontology, data or information resource, controlled vocabulary An ontology designed to represent the variety of methods used to make qualitative and quantitative clinical and phenotype measurements both in the clinic and with model organisms. obo, phenotype, clinical is listed by: SourceForge
is listed by: BioPortal
is listed by: OBO
PMID:22654893 Free, Available for download, Freely available nlx_157468 http://sourceforge.net/projects/phenoonto/, ftp://rgd.mcw.edu/pub/ontology/measurement_method/measurement_method.obo SCR_003373 2026-08-04 09:40:53 0
Mindtouch DekiWiki
 
Resource Report
Resource Website
1+ mentions
Mindtouch DekiWiki (RRID:SCR_003425) MindTouch commercial organization, software resource, source code A web based social authoring and publishing environment that adheres to open standards and RESTful design principals. It provides wiki-like ease of use with a sophisticated web services framework for rapid application development, creating flexible workflows and rapid integration. MindTouch creates a vibrant real-time information fabric by federating content from across enterprise silos, such as CRM, ERP, file servers, email, databases, web services and more. authoring, publishing, standard, web service, cloud is listed by: FORCE11
is listed by: Biositemaps
has parent organization: University of Wisconsin-Madison; Wisconsin; USA
has parent organization: SourceForge
Free, Freely available nif-0000-33097 http://sourceforge.net/projects/dekiwiki/, https://www.force11.org/node/4733 SCR_003425 MindTouch Core, DekiWiki, MindTouch Deki Wiki, Deki Wiki, MindTouch (frmly deki wiki) 2026-08-04 09:40:54 2
ECHO
 
Resource Report
Resource Website
100+ mentions
ECHO (RRID:SCR_011851) ECHO data processing software, data analysis software, algorithm resource, software resource, sequence analysis software, software application Error correction algorithm designed for short-reads from next-generation sequencing platforms such as Illumina''s Genome Analyzer II. error correction, rnaseq, rna sequence, short-read, next-generation sequencing, ngs, illumina, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21482625
DOI:10.1101/gr.111351.110
Free, Available for download biotools:echo, OMICS_01102 https://bio.tools/echo, https://sources.debian.org/src/uc-echo/ SCR_011851 ECHO: A reference-free short-read error correction algorithm 2026-08-04 09:42:52 310
TagCleaner
 
Resource Report
Resource Website
50+ mentions
TagCleaner (RRID:SCR_011846) web application, software application, standalone software, software resource A software tool which can automatically detect and efficiently remove tag sequences from genomic and metagenomic datasets. tag sequence, standalone software, web application, microbiome, genomic, metagenomic, datasets is listed by: OMICtools
is listed by: Human Microbiome Project
has parent organization: SourceForge
Available for download OMICS_01094 SCR_011846 2026-08-04 09:42:52 63
Multivariate Analysis of Transcript Splicing
 
Resource Report
Resource Website
100+ mentions
Multivariate Analysis of Transcript Splicing (RRID:SCR_013049) MATS data processing software, software application, software resource, data analysis software Software tool to detect differential alternative splicing events from RNA-Seq data. Calculates P value and false discovery rate that difference in isoform ratio of gene between two conditions exceeds given user defined threshold. Can automatically detect and analyze alternative splicing events corresponding to all major types of alternative splicing patterns. Handles replicate RNA-Seq data from both paired and unpaired study design. Differential alternative splicing events, splicing events calculation, RNA-Seq data, gene isoform ratio, alternative splicing patterns, patterns detection, patterns analysis, replicate RNA-Seq data is listed by: OMICtools
is listed by: SourceForge
has parent organization: Childrens Hospital of Philadelphia - Research Institute; Pennsylvania; USA
Free, Available for download, Freely available OMICS_01336, SCR_020941 SCR_013049 RNAseq MATS, RMATS, rMATS, MATS, RNA MATS 2026-08-04 09:43:07 192
Neuroimaging in Python
 
Resource Report
Resource Website
10+ mentions
Neuroimaging in Python (RRID:SCR_013141) NIPY, portal, software development tool, software resource, software application, community building portal, software development environment, data or information resource Community site to make brain imaging research easier that aims to build software that is clearly written, clearly explained, a good fit for the underlying ideas, and a natural home for collaboration. brain, imaging, neuroimaging, analysis, python, fmri, fmri analysis, magnetic resonance is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: Python Programming Language
has parent organization: SourceForge
has parent organization: University of California at Berkeley; Berkeley; USA
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA;
is parent organization of: Dipy
is parent organization of: NiLearn
is parent organization of: NIPY
is parent organization of: NiBabel
is parent organization of: Nipype
is parent organization of: Nitime
NIMH 5R01MH081909-02;
NIBIB 1R03EB008673-01
PMID:21897815 Revised BSD license nlx_149365 http://www.nitrc.org/projects/nipy-community http://www.nitrc.org/projects/nipype SCR_013141 NIPY Community 2026-08-04 09:43:08 24
Comparative Data Analysis Ontology
 
Resource Report
Resource Website
Comparative Data Analysis Ontology (RRID:SCR_010297) CDAO ontology, data or information resource, controlled vocabulary A formalization of concepts and relations relevant to evolutionary comparative analysis, such as phylogenetic trees, OTUs (operational taxonomic units) and compared characters (including molecular characters as well as other types). CDAO is being developed by scientists in biology, evolution, and computer science owl, biology, evolution, computer science, comparative analysis, phylogenetic tree, operational taxonomic unit, compared character, molecular is listed by: BioPortal
is listed by: OBO
is listed by: SourceForge
Public domain nlx_157371 http://purl.bioontology.org/ontology/CDAO, http://purl.obolibrary.org/obo/cdao.owl SCR_010297 2026-08-04 09:42:37 0
BWA
 
Resource Report
Resource Website
1000+ mentions
BWA (RRID:SCR_010910) BWA data processing software, alignment software, data analysis software, software resource, sequence analysis software, software application, image analysis software Software for aligning sequencing reads against large reference genome. Consists of three algorithms: BWA-backtrack, BWA-SW and BWA-MEM. First for sequence reads up to 100bp, and other two for longer sequences ranged from 70bp to 1Mbp. sequence, alignment, reference, genome, human, short, long, read, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: shovill
is related to: Proovread
is related to: BWA-MEM2
has parent organization: SourceForge
is required by: RelocaTE
PMID:19451168
PMID:20080505
DOI:10.1093/bioinformatics/btp324
Free, Available for download, Freely available SCR_015853, biotools:bwa-sw, OMICS_00654 https://sourceforge.net/projects/bio-bwa/files/, https://bio.tools/bwa-sw, https://sources.debian.org/src/bwa/ SCR_010910 Burrows-Wheeler Aligner (BWA), Burrows-Wheeler Aligner 2026-08-04 09:42:48 2291

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